ULTRASONICS SONOCHEMISTRY
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2016
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IF 4.556
Jingfu Jia,Yanzhe Gai,Wucong Wang,Yaping Zhao
Ultrasound-induced synthesis of chitosan-modified nano-scale graphene oxide (CS-NGO) hybrid nanosheets, which has great potential pharmaceutical applications, in supercritical CO 2 without catalyst was presented for the first time. The preparation process does not require organic solvent and post-processing, and CO 2 easily escapes from the product. The morphology and structure of the CS-NGO, characterized using scanning electron microscopy, transmission electron microscopy, infrared spectroscopy, X-ray photoelectron spectroscopy and thermogravimetric analysis, confirms that it was combined via the amide linkage, and had excellent dispersibility and stability toward acidic and physiological aqueous solution, which implies that it could be used as a drug-carrier. The sonication power played a crucial role in inducing forming amidation, and the conversion rate increased with the sonication time. The mechanism of this reaction was explained.
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JOURNAL OF POWER SOURCES
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2019
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IF 7.467
Hezhen Yang,Xiwei Ji,Yongtao Tan,Ying Liu,Fen Ran
Hydrogel-based electrolytes are becoming generally more preferred for electrolyte materials for quasi-solid-state/flexible supercapacitors due to their shape-controlled, high ionic conductivity , no liquid leakage , certain mechanical strength , and flexibility. Here, we develop a modified supramolecular carboxylated chitosan hydrogel electrolyte (CYCTS- g -PAM-Li 2 SO 4 ) synthesized through a free radical graft copolymerization of acrylamide monomers and chemical crosslinking . Compared with PAM-based hydrogel electrolyte (PAM-Li 2 SO 4 ), the modified hydrogel electrolyte of CYCTS- g -PAM-Li 2 SO 4 exhibits better performance including higher ionic conductivity (1.74 × 10 −2 S cm −1 ), better electrolyte absorbability (280%) as well as improved mechanical properties (2.25 MPa). A symmetric quasi-solid-state EDLC (electronic double layer capacitor) by sandwiching activated carbon film electrodes with CYCTS- g- PAM-Li 2 SO 4 as the electrolyte and carbon cloths as the current collectors. Notably, the device shows a wide potential window of 0–1.4 V and delivers a high energy density of 8.7 Wh kg −1 at a power density of 350.3 W kg −1 . Interestingly, two devices connected in series can light an LED lamp . To our knowledge, this is the first time that reported the modified carboxylated chitosan hydrogel electrolyte for quasi-solid-state supercapacitors , which has application potentials for the modified carboxylated chitosan as hydrogel electrolyte for quasi-solid-state, flexible, and portable energy storage devices.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
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IF 4.784
Zuolong Yu,Guiwei Rao,Yunxiao Wei,Jie Yu,Sihong Wu,Yupei Fang
Of late, the demand for food-packaging materials, in particular, multifunction packaging materials that are biodegradable; antibacterial; have good mechanical and barrier properties; and are edible and transparent, has increased considerably. In this study, we prepared chitosan (CS)/ε-polylysine (PL) biofilms with different CS-to-PL ratios. We studied the preparation, mechanical properties, microstructures, thermal stability, transparency, water-vapor permeability, oil permeability, and antibacterial properties of the composite CS/PL biofilms. The results demonstrate that CS/PL biofilms are mechanically strong, have good thermal stability, high transparency, low water-vapor and oil permeability, and extensive antibacterial properties that act against Escherichia coli , Bacillus subtilis , and yeast. Therefore, we therefore conclude that CS/PL biofilms are promising food-packaging materials.
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FOOD CHEMISTRY
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2025
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IF 9.8
Junhua Lu,Xinyi Yin,Qiu Wu,Mengjiao Wang,Liying Han,Shupeng Su
The fabrication of Pickering nanoemulsions, specifically food-grade ones, is challenging due to the limited availability of particles with appropriate amphiphilic wettability and sufficiently small particle size. Chitosan nanoparticles offer a promising solution due to their adjustable size and amphiphilic properties. The study investigated the effects of pH, oil phase volume fraction, chitosan concentration, and ultrasonic intensity on the formation of chitosan Pickering nanoemulsions. Nanoemulsions with droplet size of approximately 300 nm were achieved under optimal conditions of pH 6.5, oil phase volume fraction of 1 %, chitosan concentration of 1.0 wt%, and 455 W ultrasonic power for 360 min. Stability tests indicated that the nanoemulsions had good pH (2–6), ionic strength (100–500 mM), thermal (60–90 °C), freeze-thaw (3 times) and storage stabilities (0–60 days). The findings highlight the potential of chitosan nanoparticles as effective stabilizers for Pickering nanoemulsions, providing valuable insights for the development of food-grade Pickering nanoemulsions.
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DOI
PubMed
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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
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2015
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IF 2.101
Xiu-Rong Zhang,Nian-Qiu Shi,Yang Zhao,He-Yun Zhu,Jiao Guan,Ying Jin
Mitomycin C (MTC) was incorporated to a micelle system preparing from a polymer named deoxycholic acid chitosan-grafted poly(ethylene glycol) methyl ether (mPEG-CS-DA). mPEG-CS-DA was synthesized and characterized by 1H nuclear magnetic resonance (1H-NMR) and Fourier transform infrared spectroscopy. mPEG-CS-DA formed a core-shell micellar structure with a critical micelle concentration of 6.57 µg/mL. The mPEG-CS-DA micelles were spherical with a hydrodynamic diameter of about 231 nm. After poly(ethylene glycol)ylation of deoxycholic acid chitosan (CS-DA), the encapsulation efficiency and drug loading efficiency increased from 50.62% to 56.42% and from 20.51% to 24.13%, respectively. The mPEG-CS-DA micelles possessed a higher drug release rate than the CS-DA micelles. For pharmacokinetics, the area under the curve (AUC) of the mPEG-CS-DA micelles was 1.5 times higher than that of MTC injection, and these micelles can enhance the bioavailability of MTC. mPEG-CS-DA micelles reduced the distribution of MTC in almost all normal tissues and had the potential to improve the kidney toxicity caused by MTC injection.
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DOI
PubMed
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LWT-FOOD SCIENCE AND TECHNOLOGY
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2025
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IF 6.6
Linling Li,Wenxin Guo,Lu Wang,Shuiyuan Cheng,Hua Cheng
Chitosan (CTS) exhibits notable moisturizing and film-forming capabilities, whereas nano selenium (SeNPs) demonstrates antioxidant and antibacterial properties. In the present study, a CTS/Se film-forming agent was prepared by dissolving CTS, glycerol, and SeNPs in 1% (v/v) glacial acetic acid through heating and ultrasonic treatment. The results revealed that SeNPs fused with CTS via intermolecular forces, thereby enhancing the tensile strength of the CTS film. The water contact angle of the CTS film increased with an increase in SeNPs concentration. The thermal stability and water retention properties of CTS/Se were superior than CTS. In a storage experiment, the content of soluble solids in tomatoes coated with CTS/Se was higher than that in tomatoes coated with CTS and the control. The CTS/Se coating inhibited gas exchange both inside and outside the film, leading to increased activities of antioxidant enzymes. This reduced the oxidation of vitamin C in the tomatoes and decreased the content of malondialdehyde. The CTS/Se film inhibited the growth of bacteria on the tomato surface and mitigated the decline of aldehyde, alcohol and ketone aroma compounds. Consequently, the CTS/Se coating alleviated the softening, aging and rotting of tomatoes. Feeding experiments conducted on mice verified the food safety of the CTS/Se.
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Journal of Water Process Engineering
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2025
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IF 6.7
Mingi Ko,Jin-Hyuk Choi,Taesoon Jang,Soyeong Yoon,Jae-Woo Choi,Jeong-Ann Park
The interconnected macroporous graphene oxide-chitosan (GO-CS) sponge endowed the ability to simultaneously remove diclofenac (DCF), triclosan (TCS), and polystyren microplastics (PS MPs). Compared to the adsorption capacity for a single pollutant, the adsorption capacity for TCS and PS MPs was slightly decreased, indicating the partial competition of adsorption sites; however, the major adsorption sites for each pollutant differed. Fourier transform infrared and X-ray photoelectron spectroscopy analyses revealed that the adsorption of the pollutants onto the GO-CS sponge was influenced by electrostatic interactions, hydrogen bonding, and π-π interactions. The GO-CS sponge effectively removed DCF, TCS, and PS MPs even in real water samples. While DCF removal decreased in effluent and river water due to elevated pH and ion competition, TCS and PS MPs removal remained stable, driven by hydrophobic and π-π interactions. Under the flow-through condition, the highest adsorption capacities for DCF (20.49 mg/g), TCF (18.15 mg/g), and PS MPs (6.43 mg/g) were observed at the lowest flow rate (1.52 mL/min). All the breakthrough curves for the adsorption of the pollutants were described well by the Clark model, indicating their favorable and multilayer adsorption. Further, the sponge maintained its morphology and adsorption capacity (> 90.4 %) after three cycles of adsorption/desorption. Additionally, the GO-CS sponge exerted no toxicity on Daphnia magna (48 h of exposure) and no growth inhibition effect on Pseudokirchneriella subcapitata (72 h of exposure). The sponge lost 54.28 % of its total weight after being buried in the soil for 35 days, verifying its biodegradability.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Chen Shao,Mengxin Wang,Xiaohe Li,Yanhui Kong,Ao Li,Xiulian Li,Chaoqi Zhang,Yunfan Wang,Xiangquan Zeng,Hansheng Gong,Xinguang Fan
In this study, natamycin nanoparticles were prepared by anti-solvent method, and natamycin nanoparticles/chitosan coating was prepared and investigated for the preservation of sweet cherry. The results of particle size showed that the prepared natamycin nanoparticles were nano-sized, with a particle size of 209 ± 10 nm. The results of scanning electron microscope (SEM) showed that the apparent morphology was a uniform spherical structure. Fourier transform infrared spectroscopy (FTIR) proved that the prepared natamycin after the combination of Polyvinylpyrrolidone (PVP) and natamycin still had its own functional groups without new chemical bond. Compared with the control samples the solubility of natamycin increased to 1 mg/mL, leading to the enhanced antifungal activity of natamycin nanoparticles/chitosan. Natamycin nanoparticles/chitosan effectively maintained the color of sweet cherry fruits and delayed the decline of firmness, total soluble solids (TSS) and titratable acidity (TA) during storage. In particular, it effectively delayed the decay of sweet cherries, with the lowest decay rate of 10.1 %, which was 66.4 % lower than that of the control group, and there wasn't decay of sweet cherry in 35 d storage. Therefore, natamycin nanoparticles/chitosan was effectively to delay cherry fruit senescence and improved the quality of sweet cherry during the storage period.
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PubMed
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FOOD HYDROCOLLOIDS
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2025
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IF 12.4
Haifeng Mai,Xinqi Liang,Baoyi Zhang,Weijuan Huang
Emulsion gels are typically prepared via a two-step process involving emulsification followed by gelation. However, this approach is complex, as emulsion droplets may aggregate before gelation, and harsh gelation conditions may disrupt the emulsion structure and degrade encapsulated bioactive components. Recently, one-step methods have emerged, particularly under high oil content or by inducing a transition from emulsion to gel. In this study, we propose a facile one-step method to prepare uniform and stable low-oil emulsion gels. A carboxymethyl chitosan (CMC) solution and an oil phase containing cinnamon essential oil (CEO) were homogenized using a high-speed disperser at 10,000 rpm for 2 min under 23 °C, inducing a transition from solution to gel. Schiff base reactions between the amino groups of CMC and the aldehyde groups of cinnamaldehyde occurred simultaneously at the oil-water interface and in the aqueous phase, enabling concurrent emulsification and gelation. Increasing CMC concentration (1–2 wt%) and CEO content significantly reduced droplet size, accelerated gelation, and improved structural uniformity. Confocal laser scanning microscopy (CLSM) and cryo-scanning electron microscopy (cryo-SEM) analyses revealed that higher CMC concentrations promote denser gel networks, while increased CEO concentrations yield smaller and more uniformly dispersed oil droplets. Stability assessments demonstrated that emulsion gels prepared with 2 wt% CMC exhibited superior storage stability, freeze-thaw resistance, and centrifugal stability. This facile one-step method for preparing low-oil emulsion gels holds promise for applications in low-fat substitutions development and the encapsulation of sensitive bioactive compounds.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Yanhao Liu,Shubin Li,Jiang Zhu,Lili Fan,Lu Wang
Excessive blood loss caused by severe trauma is often life-threatening, so a kind of hemostatic material with superior performance is urgently needed to achieve rapid hemostasis of wounds. Here, we prepared CDCS/PF/PVA/Agar hydrogels by blending chitosan modified by catechol groups, PF127-NH 2 micelles, PVA and agarose. The hydrogel showed adjustable swelling and degradation properties. The CDCS/PF/PVA/Agar hydrogel exhibited exceptional mechanical properties with an elastic modulus of 351.4 kPa after four freeze-thaw cycles, surpassing traditional polysaccharide hydrogels by 7–20 fold. Its tissue adhesion strength reached 16.24 kPa in air and 11.23 kPa under wet conditions, enabled by catechol-mediated covalent bonding and amino group interactions. In vivo experiments demonstrated rapid hemostasis within 170 s in mouse liver injury models, reducing blood loss by 75.4 % compared to untreated controls. This study provides a robust strategy for designing polysaccharide hydrogels integrating mechanical resilience, rapid hemostasis, antibacterial activity, and biosafety, offering significant potential for clinical wound management.
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DOI
PubMed
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INDUSTRIAL CROPS AND PRODUCTS
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2025
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IF 6.2
Jing Zhou,Rourou Wang,Ming Niu,Zhenghua Zhang,Minrui Zhu,Lumei Pu,Weibing Xu,Runtian Ma
The infection caused by Fusarium oxysporum severely threatens cotton production. Herein, carvacrol-chitosan nanoparticles (CS@CAR) are facilely fabricated using tripolyphosphate as a crosslinker. When the initial mass ratio of chitosan to carvacrol is 1:0.4, the nanoparticles show the best stability and drug loading. Morphological analysis reveals that the CS@CAR nanoparticles possesses a uniform spherical structure with an average diameter of approximately 150 nm. About 51.23 % of total CAR is released within the 48 h in the simulated fungal infection environment. The contact angle of drug-loaded particles decreases by 12.2 and 6.6 ° compares with that of pure water and unloaded particles. The fluorescence intensity of leaves before and after rain erosion is 1.3 times and 1.2 times that of the pure water control group by fluorescence imaging analysis. The bacteriostatic activity of drug-loaded nanoparticles is 6–7 times that of non-drug-loaded nanoparticles. The contents of nucleic acid, protein, and malondialdehyde leaked by spores after treatment with drug-loaded particles are 1.4, 1.5 and 2.3 times those in the non-drug-loaded particle treatment group, respectively. The CS@CAR entirely prevents Fusarium oxysporum from infecting cotton leaves in spore inoculation experiments. The CS@CAR nanoparticles are expected to be used to prevent and control the infection of Fusarium oxysporum on cotton.
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ELECTROCHIMICA ACTA
·
2025
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IF 5.6
Dianhao Zhao,Ao Wang,Ziyi Wang,Yuchao Wang,Shi Chen,Shiqing Zeng,Min Zhang,Ping Zong
In traditional Si-based anodes, bio-based binders can partially address the inherent drawbacks of silicon anodes. However, plenty of inactive materials hinder the improvement of the electrochemical performance of traditional Si-based anodes. To settle the issues above, sodium alginate (SA)/chitosan (CS) double-network is constructed to design a free-standing Si anode. The two physically cross-linked networks, reinforced by carbon nanotubes (CNTs), form a 3D-structured electrode that firmly anchors Si nanoparticles via forming dynamic hydrogen bonds. Furthermore, the in-situ -reduced copper particles act as the point-like conductive agent, CNTs function as the connecting conductive networks, and SA/CS aerogel sheets serve as the conductive plane, synergistically forming a three-dimensional conductive network (points-lines-planes) around Si particles. This double-network structure effectively alleviates Si volume expansion and endows the free-standing electrode with a high capacity of 1194 mAh/g (based on the whole weight of the electrode) and an excellent capacity retention rate of 85.1% after 100 cycles at 0.5 A/g. This strategy is anticipated to produce high-performance free-standing silicon anodes, therefore supporting lightweight and high-capacity electronics.
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