JOURNAL OF MATERIALS SCIENCE
·
2015
·Vol. 51
·期 3
·1363-1375
·
IF 2.371
Luo Yan-Ling,Bai Rui-Xue,Xu Feng,Chen Ya-Shao,Li Hua,Dai Si-Si,Ma Wen-Bo
Novel multiwalled carbon nanotube graft polyethylene glycol -block -polystyrene copolymer nanohybrids (MWCNTs- g -PEG- b -PS) were prepared via atom transfer radical polymerization using carboxylated MWCNTs (MWCNTs–COOH) as a conductive carrier. The chemical structure and the compositions of graft copolymer nanohybrids were characterized by Fourier transform infrared spectroscopy, Raman spectroscopy, thermogravimetry, and gas chromatography, and the morphologies and dispersion behavior were observed by ultraviolet visible spectrophotometer, scanning electron microscope, and transmission electron microscope etc. The MWCNTs- g -PEG- b -PS-grafted copolymer nanohybrids were fabricated into conductive composite thin film sensors to investigate their responsiveness to benzene vapor. The influence of the molecular weights or compositional ratios of PEG and PS blocks on the conductivity of the conducting polymer nanohybrids and responsibility towards benzene vapor was investigated. The conducting polymer nanohybrid film sensors were demonstrated to possess the characteristics of quick response and good restorability, repeatability, and stability.
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Materials Science & Engineering C-Materials for Biological Applications
·
2016
·
IF 3.42
Ruixue Yin,Nan Zhang,Wentao Wu,Kemin Wang
Cyclic acetals based biomaterial without acidic products during hydrolytic degradation is a promising candidate for tissue engineering applications; however, low hydrophilicity is still one limitation for its biomedical application. In this work, we aim to achieve non-water-swellable cyclic acetal networks with improved hydrophilicity and surface wettability by copolymerization of cyclic acetal units based monomer, 5-ethyl-5-(hydroxymethyl)-β,β-dimethyl-1, 3-dioxane-2-ethanol diacrylate (EHD) and methoxy poly(ethylene glycol) monoacrylate (mPEGA) under UV irradiation, to avoid swelling of conventional hydrogels which could limit their applicability in particular of the mechanical properties and geometry integrity. Various EHD/mPEGA networks were fabricated with different concentrations of mPEGA from 0 to 30%, and the results showed photopolymerization behavior, mechanical property and thermal stability could not be significantly affected by addition of mPEGA, while the surface hydrophilicity was dramatically improved with the increase of mPEGA and could achieve a water contact angle of 37° with 30% mPEGA concentration. The obtained EHD/mPEGA network had comparative degradation rate to the PECA hydrogels reported previously, and MTT assay indicated it was biocompatible to L929 cells.
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RSC Advances
·
2016
·Vol. 7
·期 1
·318-326
·
IF 3.289
Pham Van Trinh,Nguyen Ngoc Anh,Bui Hung Thang,Le Dinh Quang,Nguyen Tuan Hong,Nguyen Manh Hong,Phan Hong Khoi,Phan Ngoc Minh,Phan Ngoc Hong
In this study, nanofluid based ethylene glycol (EG) containing Cu nanoparticles decorated on a Gr–MWCNT hybrid material (Gr–MWCNT/Cu) was synthesized successfully for the first time via a chemical reduction method. The SEM, HRTEM, FTIR and XRD studies revealed that Cu nanoparticles with an average diameter of 18 nm were well decorated on the surface of both MWCNTs and graphene sheets. The nanofluids containing Gr–MWCNT/Cu material showed good stability and a maximum thermal conductivity enhancement of 41% at 60 °C for the nanofluid containing 0.035 vol% material compared to EG alone. The enhancement is due to the combination of the high thermal conductivity of graphene, CNT and Cu nanoparticles as well as the higher surface area of the Gr–MWCNT/Cu hybrid structure. Experimental results of thermal conductivity were evaluated using different theoretical models, amongst which the Hamilton–Crosser model was found suitable for predicting the thermal conductivity of the nanofluid.
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DRUG DELIVERY
·
2016
·
IF 4.843
Chang Li,Yan Shen,Chunmeng Sun,Nihad Cheraga,Jiasheng Tu
To investigate the physicochemical properties, immunosafety and chronic toxicity of monomethoxypoly(ethylene glycol)-b-poly(lactic acid) (mPEG-PLA), a copolymer used as a carrier for paclitaxel (PTX) delivery. The H-Nuclear Magnetic Resonance (H-NMR), dynamic light scattering and fluorescence probe technique were conducted to determine the physicochemical properties of mPEG-PLA copolymer. PTX-loaded polymeric micelles were characterized regarding their particle size, entrapment efficiency (EE), drug loading (DL), in vitro drug release and hemolysis rate. The complement activation in human serum and mast cells degranulation were performed by ELISA and RBL-2H3 cell line in vitro, respectively. The chronic toxicity study was carried out on beagle dogs. The optimized PTX-loaded mPEG-PLA (40/60) micelles showed a particle size of 37 nm and EE of 98.0% with a DL of 17.0% w/w. Transmission electron microscopy (TEM) analyses showed that mPEG-PLA (40/60) micelles have spherical shape with dense core. In vitro release study showed a sustained release for 24 h, and the hemolysis study revealed that mPEG-PLA (40/60) was a safe nanocarrier for intravenous administration. mPEG-PLA (40/60) showed a lower complement activation ability compared to mPEG-PLA (50/50) and Cremophor® EL (Cr EL). Furthermore, the chronic toxicity of PTX-loaded mPEG-PLA (40/60) micelles was significantly lower than those of mPEG-PLA (50/50) and Cr EL.
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POLYMER INTERNATIONAL
·
2016
·Vol. 65
·期 10
·1172-1178
·
IF 2.414
Shuyan Yang,Wenjian Wu,Yuanqi Jiao,Hongbo Fan,Zhuodi Cai
The plasticizing and thermostabilizing effect of poly(ethylene glycol)–polyhedral oligomeric silsesquioxane (PEG-POSS) on poly(vinyl chloride) (PVC) is discussed thoroughly in this work. As PEG-POSS content increases, PVC becomes more flexible and the decomposition temperature of PVC increases slightly. Meanwhile, the temperature of maximum HCl emission is elevated from 265.3 °C in neat PVC to 285.7 °C in PVC nanocomposites, with the peak intensity of HCl emission decreased by 30.8%, and a new lower intensity of HCl emission peak appearing at much higher temperature (around 370 °C), which is in accordance with the maximum degradation temperature of PEG-POSS. Thereby, a possible dehydrochlorination mechanism is suggested according to the fact that the electron donor effect of ether groups would stabilize the C Cl bonds by means of more electron cloud stacked in those bonds, which agrees with Fourier transform infrared and X-ray photoelectron spectroscopy experiments in terms of hydrogen bonds. © 2016 Society of Chemical Industry
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
·
2016
·Vol. 105
·期 7
·1737-1746
·
IF 2.881
Weiping Wang,Zhi Zheng,Xin Huang,Wenling Fan,Wenkui Yu,Zhibing Zhang,Lei Li,Chun Mao
Polyethylene glycol (PEG) and heparin (Hep) were grafted onto polysulfone (PSF) membrane by plasma-induced surface modification to prepare PSF–PEG–Hep membranes used for artificial lung. The effects of plasma treatment parameters, including power, gas type, gas flow rate, and treatment time, were investigated, and different PEG chains were bonded covalently onto the surface in the postplasma grafting process. Membrane surfaces were characterized by water contact angle, PEG grafting degree, attenuated total reflectance-Fourier transform infrared spectroscopy, ultraviolet–visible spectrophotometry, X-ray photoelectron spectroscopy, critical water permeability pressure, and scanning electron microscopy. Protein adsorption, platelet adhesion, and coagulation tests showed significant improvement in the hemocompatibility of PSF–PEG–Hep membranes compared to pristine PSF membrane. Gas exchange tests through PSF–PEG6000–Hep membrane showed that when the flow rate of porcine blood reached 5.0 L/min, the permeation fluxes of O 2 and CO 2 reached 192.6 and 166.9 mL/min, respectively, which were close to the gas exchange capacity of a commercial membrane oxygenator. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1737–1746, 2017.
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CARBON
·
2016
·
IF 6.198
Nan Wang,Hai Fan,Jianchao Sun,Zhenwei Han,Jing Dong,Shiyun Ai
Fluorine-doped carbon nitride (F C 3 N 4 ) quantum dots were successfully synthesized on a large scale by a facile ethylene glycol-assisted ultrasonic method using bulk F C 3 N 4 powder as the precursor and ethylene glycol as the solvent. Characterization results show that high-quality F C 3 N 4 quantum dots with a uniform size of 1.5–2.0 nm were successfully prepared in ethylene glycol. Ethylene glycol is found to play an important role in the synthesis of quantum dots. Doping of fluorine in C 3 N 4 could adjust the band gap structure of C 3 N 4 , resulting in altering the emission peak position and increasing the fluorescent intensity. The as-prepared F C 3 N 4 quantum dots in ethylene glycol show much higher fluorescent intensity with the quantum yield of 39.03%. The prepared F C 3 N 4 quantum dots were successfully applied as a fluorescent probe for bacterial imaging.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 43
·45446
·
IF 1.86
Haiquan Zhang,Qinrong Sun,Yanping Yuan,Xiaoling Cao
Poly(ethylene glycols) (PEGs) are phase change materials (PCMs) that exhibit undesirable heat transfer properties, which restrict their industrial utility. Apart from the intrinsic material properties, a large quantity of micropores in the crystalline PEG polymers cause poor heat transfer performance. In this work, the formation and growth of micropores are reported through in situ characterization. The addition of a nanoscale thermal-energy-conducting medium into PCMs has been proposed for reducing their porosity. The mechanism for reducing porosity is reported for prepared composite PCMs. The intrinsic causes are thought to be the following. Metal oxide nanoparticles can migrate with the liquid PEG flow, which can reduce the thermal stresses in the crystal growth process. In addition, the nanoscale medium promotes heterogeneous nucleation. The results of this study show that reducing the porosity of the polymer crystals is an important approach for improving the heat transfer properties of the PEG PCMs. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 45446.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Dongsheng Zhao,Jiyu Song,Ruohan Liang,Junxia Liu,Jun Xu,Guicai Liu,Xiaohang Ma,Zonghua Wang,Kang Xie
The low permeability and high fouling susceptibility of nanofiltration (NF) membranes limit their widespread application in water treatment. In this study, a polyethylenimine (PEI)-based NF membrane was synthesized via interfacial polymerization with a mixture of PEI and the polyethylene glycol derivative Jeffamine (JA) as the aqueous phase comonomer and trimesoyl chloride as the organic phase monomer. A 1/1 mass ratio of PEI to JA with a total aqueous phase monomer concentration of 1.00 % (weight/volume) yielded NF membranes with optimal water permeance and satisfactory salt exclusion. Compared with the pristine membrane, the JA-doped PEI-based (JA/PEI) membrane exhibited enhanced surface hydrophilicity, a more positively charged surface, an enlarged effective pore size, a thinner polyamide layer, and greater surface roughness. Furthermore, the optimal JA/PEI membrane was more resistant to protein fouling because of the lower adhesion energy between it and protein molecules. Additionally, the optimal JA/PEI membrane exhibited excellent permeation flux and comparable retention performance in the treatment of actual drinking water. This JA-doping strategy provides a facile avenue to fabricate NF membranes with higher permeability and better antifouling ability for water treatment applications.
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BIOMACROMOLECULES
·
2024
·
IF 5.5
Weiling Lu,Xianjin Wang,Changchang Kong,Shijunyin Chen,Chengtao Hu,Jianfa Zhang
Hydrogels composed of natural polysaccharides have been widely used as filling materials, with a growing interest in medical cosmetology and skin care. However, conventional commercial dermal fillers still have limitations, particularly in terms of mechanical performance and durability in vivo. In this study, a novel injectable and implantable hydrogel with adjustable characteristics was prepared from succinoglycan riclin by introducing PEG diglycidyl ether as a cross-linker. FTIR spectra confirmed the cross-linking reaction. The riclin hydrogels exhibited shear-thinning behavior, excellent mechanical properties, and cytocompatibility through in vitro experiments. Furthermore, when compared with subcutaneous injection of a commercial hyaluronic acid hydrogel, the riclin hydrogels showed enhanced persistence and biocompatibility in Balb/c mice after 16 weeks. These results demonstrate the great potential of the riclin-based hydrogel as an alternative to conventional commercial soft tissue fillers.
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Polymers
·
2025
·Vol. 17
·期 7
·888
·
IF 4.9
Muzammil Hussain Memon,Md. Asraful Alam,Qiyuan Xie,Abdul Rahman Abbasi,Lele Wang,Jingliang Xu,Wenlong Xiong
Multi-component electrolyte additives may significantly contribute to improving the performance of rechargeable aqueous zinc-ion batteries. Herein, we propose a mixed electrolyte system employing polyethylene glycol 200 (PEG200) and quaternized kraft lignin (QKL) as co-additives in Zn//MnO2batteries. Reduced corrosion and the suppression of the hydrogen evolution reaction on the zinc electrode were achieved when 0.5 wt.% of PEG200 and 0.2 wt.% of QKL were added to the reference aqueous electrolyte. This optimized electrolyte, 0.5% PEG200 + 0.2% QKL, was conducive to improving Zn reversibility in Zn//Zn symmetric batteries and resulted in higher cycling stability, with a coulombic efficiency of 98.01% under 1 mA cm−2and 1 mAh cm−2for Zn//Cu cells. Furthermore, Zn//MnO2full batteries with 0.5% PEG200 + 0.2% QKL presented good overall electrochemical performance and exhibited a decent discharge capacity of around 85 mAh g−1after 2000 cycles at 1.5 A g−1. As confirmed by X-ray diffraction and scanning electron microscopy, a dominant (002) oriental dendrite-free Zn deposition was achieved on the zinc anode of the battery using 0.5% PEG200 + 0.2% QKL, and the byproducts were also reduced significantly. This study has contributed to the development of electrolyte co-additives for zinc-ion batteries.
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JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Yutong Sun,Qi Liu,Zhe Wang,Jinlan Zhang
Polyethylene glycol (PEG) is one kind of polymeric pharmaceutical excipient widely used in pharmaceutics. The critical quality attributes (CQAs) are essential to their physicochemical properties and functions. However, there is no effective strategy to rapidly and simply analyze PEG multi-CQAs. Herein, a novel strategy was developed to simultaneously evaluate four PEG CQAs including average degree of polymerization, average molecular weight, weight-average molecular weight and polydispersity based on comprehensive identification and mathematical models of PEG components. In this strategy, an ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MS) method was established and different types and concentrations of mobile phase additives were optimized to overcome the mass discrimination effect of PEG components. MS data was deconvoluted by molecular feature extraction to identify PEG components with multi-charged quasimolecular ions. A total of 168 PEG components were identified in PEG mixture samples. Mathematical models were established based on the logarithmic relation between the degree of polymerization and retention time and a theoretical database including 220 detected and predicted PEG components was constructed to rapidly recognize and identify PEG components in PEG excipients and preparations samples. The calculation formulae for multi-CQAs using UHPLC-Q-TOF/MS analysis results were created, then the strategy workflow to evaluate multi-CQAs was established and validated by PEG standards, showing high efficiency for quality control of PEG excipients and their preparations.
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