INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Tengfei Xiong,Mingyue Yu,Mei Li,Christopher A. Reilly,Xinghui Qiu
Capsaicin and dihydrocapsaicin are the principal pungent compounds in hot peppers. The generalist Helicoverpa armigera and the specialist H. assulta are two of the few insects that can feed on hot pepper fruits. To further understand the mechanisms behind physiological adaptation to capsaicinoids in the two agricultural pests, we investigated the transcriptional response and metabolism capacity of CYP6B6 orthologs from the two closely related species to the capsaicinoids. The results showed that the expression of CYP6B6 was either weakly or moderately induced by capsaicin in a tissue-specific and dose-dependent manner. CYP6B6 induction to greater extent was observed in the larval midguts of the cotton bollworms, indicating that inducible defense is more robust in the generalist. The two CYP6B6 enzymes were able to efficiently metabolize both capsaicin and dihydrocapsaicin, and HassCYP6B6 exhibit a slightly higher activity towards capsaicin than HarmCYP6B6, as evaluated by the specific activity and Vmax values. Multiple known and yet to be elucidated metabolites were detected in the reactions catalyzed by CYP6B6s, with dehydrogenation at the terminal carbon followed by N-macrocyclization and aliphatic hydroxylation being the dominant pathways. The data support the hypothesis that these two Helicoverpa species have well adapted to capsaicinoids via their high P450-mediated detoxification ability.
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DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 32
·期 51
·2208676
·
IF 19.924
Bo Pang,Zuquan Jin,Yunsheng Zhang,Zhiyong Liu,Wei She,Penggang Wang,Yong Yu,Xiaoying Zhang,Chuansheng Xiong,Ning Li,Guowen Sun,Peng Zhao,Guojian Liu,Xiaoyun Song,Song Gao
Cement-based sensors (CBSs) have demonstrated potential in structural health monitoring (SHM) despite rare applications due to their poor flexibility and sensing accuracy/protection with robustness. Herein, a promising strategy is reported to design a waterborne epoxy resin (WEP)-modified cement-based composite coating sensorcapable of simultaneous stable SHM and durable protection. The interpenetrating network (IPN) formed by WEP within cement paste is bionic to the toughness and crack resistance of biological muscle tissue and balances the ion permeation performance and polarization of hydration products. The polymerization-redispersion progress and mechanism of calcium silicate hydrate (C-S-H) gel modified with [3-(2-aminoethylamino)-propyl]trimethoxysilane silsesquioxane (C-POSS) are characterized and revealed. The results show that the muscle-like IPN increases the cement-based coatings’ maximum deflection angle to 30° and improves the monitoring accuracy of compressive, tensile, and fatigue microchanges of concrete structures to more than 95%. The POSS···Ca 2+ ···C-S-H interaction in C-POSS partially transferred the intra-adhesive hydrogen bonds surrounding the nanoconducer into electrostatic bridging ones to maintain an excellent electromechanical conductive dispersion.
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高影响因子
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2017
·
IF 3.471
Yunwu Zheng,Fei Wang,Xiaoqin Yang,Yuanbo Huang,Can Liu,Zhifeng Zheng,Jiyou Gu
The main objective of this work was to study aromatics production via the catalytic pyrolysis upgrading of biomass using metal-loaded modified H-ZSM-5. M-ZSM-5 catalysts were prepared through the impregnation method with Zn, Ga, Ni, Co, Mg and Cu. The prepared M-ZSM-5 catalysts were evaluated by x-ray diffraction, thermal desorption spectroscopy and scanning electron microscopy. The properties, composition and product distribution of bio-oil were also analysed. Results showed that the M-ZSM-5 catalysts yielded a higher amount of non-condensable gas at the expense of the liquid yields. The Ga-ZSM-5 catalysts produced the highest yields of bio-oil (25.76 wt%), but the lowest amount of coke (22.08 wt%) compared with the unmodified ZSM-5 catalyst (33.38 wt%). The content of the single-ring aromatics prepared by using the Zn-ZSM-5 catalysts was the highest at 90.28 wt%, whereas that of the polycyclic aromatic hydrocarbon prepared by the Ni-ZSM-5 catalysts was the highest at 31.36 wt%. Moreover, the selectivity of the single-ring aromatic hydrocarbons, such as C7 and C8, were significantly affected by the use of the M-ZSM-5 catalysts. The Zn-ZSM-5 catalysts were the most selective for toluene and xylenes with contents of 36.52 wt% and 35.32 wt%, respectively, whereas the Co-based catalysts were the most selective for indene. The Ni-based catalysts can obviously improve the selectivities of benzene production and C10+ polycyclic aromatic hydrocarbons. Zn-ZSM-5 was the most effective catalyst that can be used in the production of aromatic hydrocarbons.
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高影响因子
ADVANCED SYNTHESIS & CATALYSIS
·
2017
·Vol. 359
·期 13
·2215-2221
·
IF 5.646
Wenhui Zhu,Yingcai Ding,Zhaogang Bian,Ping Xie,Baojun Xu,Qiujie Tang,Wei Wu,Aihua Zhou
Sulfenylation is an important transformation to generate C−S bonds in organic synthesis. Here, two three-component synthetic protocols have been developed by using imidazo[1,2- a ]pyridine, inorganic, odorless S 8 and alcohols or arylboronic acids as reactants to make alkylthio-/arylthio-substituted imidazo[1,2- a ]pyridine derivatives via C( sp 2 )–H functionalization. The reactions proceeded with high efficiency and broad functional group tolerance, affording the products regioselectively and in good yields.
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高影响因子
BMC Chemistry
·
2019
·Vol. 13
·期 1
·1-15
·
IF 0
Guo J.,Ma Yu L.,Yu Jia Y.,Gao Yu J.,Ma Ning X.,Wu Xiao Y.
Herein, 2-(2-methoxyphenoxy)-1-phenylethanol (β- O -4), 2-methoxyphenyl anisole (α- O -4) and 4-phenoxyphenol (4- O -5) were selected as typical lignin model compounds. Given the effectiveness of traditional acid–base catalysts for lignin depolymerisation, a novel Ni/CaO–H-ZSM-5(60) catalyst was prepared to investigate the difficulty level of C–O bond of three model compounds cleavage in ethanol. It was observed that Ni/CaO–H-ZSM-5(60) had prominent performance on the C–O bond cleavage at very mild conditions (140 °C, 1 MPa H 2 ). Among them, the C–O bond of α- O -4 and β- O -4 could be completely cleaved within 60 min. Although the C–O bond of 4- O -5 had high bond energy, 41.2% of conversion was occurred in 60 min. The introduction of CaO could regulate the acidity of H-ZSM-5 to enhance the ability to break C–O bonds. Moreover, the possible pathways of C–O ether bonds in three lignin model compounds cleavage were proposed in order to selectively obtain target products from the raw lignin degradation.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2021
·
IF 3.764
Jianchuan Liu,Yunbo Zhang,Yao Miao,Ying Yang,Ping Li
The mechanism of lithium ion-sieve adsorbing Li+ ions from brines is based on the Li+/H+ ion exchange, where Li+ ions in brines are adsorbed on ion-sieves to displace H+ ions, and the displaced H+ ions are released in brines in turn. If the released H+ ions are accumulated in brines, then brines become acidic, not conducive to Li+ ions adsorption on ion-sieves. Therefore, it is important to regulate the pH value in brines to be more than 7 during the lithium recovery from brines using ion-sieves. Instead of the addition of the traditional ammonia buffer solution, the alkaline anion exchange resins are used to regulate the pH value of brines in this work since the addition of ammonia buffer solution in brines would cause the secondary pollution in Salt Lake with a high ammonia nitrogen emission value. The alkaline anion exchange resins contain the amine functional groups to neutralize the released H + ions in brines that enhance the adsorption performance of lithium ion-sieves. Like ammonia buffer, the amine functional groups of alkaline resins without more free OH– ions in brine will avoid the precipitation of high content of magnesium in brines. Here, seven kinds of alkaline anion exchange resins are used to neutralize the released H+ ions during lithium recovery from brines using homemade granular titanium-type lithium ion-sieves (PVB-HTO ion-sieves). The process intensification for lithium recovery from brine by lithium ion-sieves with the addition of alkaline anion exchange resins is evaluated based on experimental results, and a green lithium recovery technology from brine with a high Mg/Li ratio will be developed.
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高影响因子
MACROMOLECULAR BIOSCIENCE
·
2015
·Vol. 15
·期 10
·1411-1422
·
IF 3.851
Yan-Ling Luo,Mei Han,Feng Xu,Ya-Shao Chen,Yong-Qin Zhang
pH-Responsive H-type poly(methylacrylic acid- block -four hydroxyl terminated poly(butadiene-acrylobitrile)- block -poly(methylacrylic acid (PMAA 2 - b -HTPBN- b -PMAA 2 ) block copolymers were synthesized via atom transfer radical polymerization and the follow-up hydrolysis, and characterized by 1 H NMR, FT-IR and SEC . The block copolymers could self-assemble into nanoscale spherical core-shell micelle aggregates in aqueous solution, and the physicochemical properties depended on the system composition and pH media, with pH phase transition at 5.7–6.1. The copolymer micelle aggregates exhibited pH-triggered drug release and cytotoxicity, and could potentially be used as drug targeting release carriers.
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高影响因子
Journal of Materials Chemistry C
·
2021
·Vol. 9
·期 25
·8020-8028
·
IF 7.393
Minghao Yi,Xunjun Chen,Peter S. Shuttleworth,Lewen Tan,Yunqing Ruan,Yixin Xu,Jiefeng Zheng,Shufang Wu,Sen Hu,Simin Xie,Zhixing Guan,Guoqiang Yin,Yingde Cui
Transparent and easily fabricated films were obtained through the coupling of eugenol, a bio-sourced feedstock, and poly(methylhydrosiloxane), via the Piers–Rubinsztajn reaction and Pt-catalysed hydrosilylation. The precursor reagents are readily available and economical, and the reaction process used was mild and easily undertaken. Additionally, poly(methylhydrosiloxane), having an abundant source of pendant Si–H groups, can be cross-linked with eugenol at multiple juncture points, and thus the eugenol content in these films ranges from 13.12 to 45.42 wt%. It was found that as the eugenol content increased, the thermal stability of the films also improved, with T10% and Rw at 700 °C ranging from 350.1 to 584.3 °C and 46.41 to 86.63%, respectively, which is higher than other analogous biomass-derived polysiloxanes. Crucially, the prepared films also exhibited suitable optical properties, with a >90% transmittance within the 430–1100 nm region and near 100% absorbance in the UV region (<350 nm), verifying their potential applications as optical encapsulants. Aside from good light transmittance, the refractive index of the films increased from 1.44 to 1.52 (at 450 nm) with higher ratios of eugenol. This demonstrates their suitability for use as high-refractive index (>1.5) LED encapsulants and also in stacked multi-layer reflectors. In addition, to protect the encapsulated chips from moisture erosion, these films exhibit good water vapour barrier properties and water repellence.
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高影响因子
CELL BIOLOGY INTERNATIONAL
·
2024
·
IF 3.3
Guang Yang,Xin Shi,Meixia Zhang,Kaiwen Wang,Xin Tian,Xiaofeng Wang
Oral squamous cell carcinoma (OSCC) is the most common oral malignancy. DEAD/H-box helicase 11 (DDX11), a DNA helicase, has been implicated in the progression of several cancers. Yet, the precise function of DDX11 in OSCC is poorly understood. The DDX11 expression in OSCC cells and normal oral keratinocytes was evaluated in the Gene Expression Omnibus database (GSE146483 and GSE31853). SCC-4 and CAL-27 cells expressing doxycycline-inducible DDX11 or DDX11 shRNA were generated by lentiviral infection. The role of DDX11 in OSCC cells was determined by 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay, colony formation assay, flow cytometry assay, TUNEL staining, and western blot. The effects of DDX11 on tumor growth were explored in a xenograft nude mouse model. The relationship between DDX11 and transcription factor Yin Yang-1 (YY1) was researched using the dual luciferase report assay and chromatin immunoprecipitation assay. DDX11 expression was significantly upregulated in OSCC cells. Knockdown of DDX11 inhibited cell proliferation, induced cell cycle arrest, and suppressed PI3K-AKT pathway, while DDX11 overexpression showed opposite effects. The number of apoptotic cells was increased in DDX11 silenced cells. DDX11 upregulation or knockdown accelerated or suppressed tumor growth in vivo, respectively. Moreover, the YY1 bound and activated the DDX11 promoter, resulting in increasing DDX11 expression. Forced expression DDX11 reversed the anticancer effects of YY1 silencing on OSCC cells. DDX11 has tumor-promoting function in OSCC and is transcriptionally regulated by YY1, indicating that DDX11 may serve as a potential target for the OSCC treatment.
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DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2022
·Vol. 33
·期 22
·17587-17598
·
IF 2.779
Yu Bo,Miao Chun,Wang Dandan,Li Hongji,Sun Dongshu,Jiang Wei,Liu Chunbo,Che Guangbo
The development of high-efficiency heterojunction with improved photocatalytic property is regarded as a promising way to decontaminate wastewater. In this study, Z-Scheme g-C 3 N 4 /H-TiO 2 heterojunctions with different proportions were synthesized. The photocatalytic degradation of rhodamine B (RhB) was studied under visible light irradiation. Among them, 10% g-C 3 N 4 /H-TiO 2 photocatalyst had the best performance, and the degradation rate of RhB was 65% within 120 min. In addition, 10% g-C 3 N 4 /H-TiO 2 photocatalyst had high stability, and its photocatalytic activity did not decrease significantly after four cycles. Through photocurrent analysis, it is found that the photogenerated carriers have obviously excellent separation and transfer characteristics, which makes the 10% g-C 3 N 4 /H-TiO 2 photocatalyst have good degradation performance. Electron paramagnetic resonance (ESR) experiments showed that ·OH and ·O 2 − were active radicals during degradation.
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高影响因子
Bioresources and Bioprocessing
·
2018
·Vol. 5
·期 1
·1-11
·
IF 0
Liu Xin,Wang Weiwei,Hu Haiyang,Lu Xinyu,Zhang Lige,Xu Ping,Tang Hongzhi
Background Benzofuran and its derivatives contain central pharmacophores and are important structures in medicinal chemistry. Chemical synthesis of benzofuran rings often requires expensive catalysts and stringent operational conditions. Biosynthesis is recognized as a promising way to save energy and produce valuable compounds. Dioxin biodegradation pathways can form several benzofuran derivatives, and these pathways may be a better choice for further synthesis of important biological compounds. 2-Hydroxy-4-(3′-oxo-3′ H -benzofuran-2′-yliden)but-2-enoic acid (HOBB), a benzofuran derivative, can be biosynthesized from dibenzofuran (DBF) through co-metabolic degradation in a lateral dioxygenation pathway. Results Efficient biosynthesis of HOBB was observed using whole cells of Pseudomonas putida strain B6-2. After cultivation in LB medium containing biphenyl, the cells were suspended to an OD 600 of 5 to conduct biosynthesis in the presence of 0.5-mM DBF at pH 7 for 8 h. The bacterial cells were used twice to degrade approximately 0.70-mM DBF, and in batch process, accumulated about 0.29-mM HOBB. HOBB could be easily purified from the reaction with ethyl acetate using the neutral-acid extraction method, and 13.58 ± 0.31 mg of HOBB was obtained from 22.49 ± 0.74-mg DBF with an overall production yield of 60.4% (w/w). The product HOBB, which is a yellow powder, could be detected and identified by LC–MS, GC–MS, and NMR. Conclusions In this study, a new biological route was developed to produce HOBB from DBF using whole cells of P. putida B6-2 (DSM 28064). The biosynthesis of HOBB may contribute to studies of the DBF lateral pathway and provide a new green route for synthesizing benzofuran derivatives with pharmacological activities.
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ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Shuai Han,Cai Xu,Jun Li,Jia Guo,Jianhai Yang,Xiaozhong Wang,Liyan Dai
The selective C−H bond oxidation of toluene to benzaldehyde using molecular O2 with non-noble metal catalysts is challenging but desirable. Herein, a series of high-entropy oxides (FeCoNiCrMn)3O4 supported on mesoporous N-doped carbon was fabricated via a reverse impregnation and calcination method (denoted as HEOs@NC). It was found that high-entropy oxides (FeCoNiCrMn)3O4 nanoparticles were distributed well onto the surface of N-doped carbon, and a distinct interface between them was observed, contributing to the formation of metal-support electronic interaction. XPS and Bader charge results verified that an electron was transferred from (FeCoNiCrMn)3O4 to N-doped carbon. Under the optimized reaction conditions, 12.2% of toluene conversion and 2.0 ×10−4 mmol mg−1cat. h−1 of benzaldehyde formation rate could be obtained with 1.5HEOs@NC catalyst. Moreover, DFT calculations revealed that the supported (FeCoNiCrMn)3O4 displayed stronger adsorption ability toward N-hydroxyphthalimide, and the formation of *PhCH2OH was determined as the rate-determining step. A lower energy barrier was achieved over the supported HEOs owing to the interfacial interaction between (FeCoNiCrMn)3O4 and N-doped carbon. This work developed a supported high-entropy oxides catalyst by rational design of interfacial engineering for the aerobic C−H bond oxidation of toluene.
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高影响因子
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