查找使用阿拉丁产品的科研文献

Imidazolium-Based Polymeric Ionic Liquids with Short Alkyl Chains as Green Corrosion Inhibitors for Mild Steel in 1 M HCl: Experimental and Theoretical Investigations

Haidong Jia,Han Jia,Qiuxia Wang,Yingbiao Xu,Bowen Wang,Qiang Wang,Xu Li,Zhe Wang,Kaihe Lv,Pan Huang

A novel polymeric ionic liquid (PDBA-IL-NH2) using imidazolium ionic liquids with short alkyl chains as monomers and two control ionic liquids (PDBA-IL-OH and PIL-NH2) were synthesized. Their inhibition properties and mechanisms were explored via surface analysis, weight loss tests, electrochemical studies, and adsorption isotherm analysis. The corrosion inhibition efficiency (CIE) of PDBA-IL-NH2 gradually increased with increasing concentration, and the largest efficiency was 94.67% at 100 ppm. At the same concentration (50 ppm), the corrosion inhibition abilities of inhibitors were in the order of PDBA-IL-NH2 > PDBA-IL-OH > PIL-NH2 > IL-NH2. Based on the experimental investigation, the synergistic effect of electrostatic interaction, protonation, and electron donor–acceptor interaction facilitated the intensive entanglement and coverage of PDBA-IL-NH2 with the reticulated form on the metal, and the generated densest films protected the metal from the corrosive media. Ultimately, the theoretical results of molecular dynamics simulations and quantum chemical study were in high agreement with the experimental data, which confirmed the proposed inhibition mechanisms on the microscopic scale. This study contributed valuable perspectives to the design of efficient and ecofriendly corrosion inhibitors.

Low MWCO non-polyamide nanofiltration membranes synthesized in aqueous by coupling with catechol-amine chemistry and the oxidation-induced self-polymerization of m-phenylenediamine

Runkai Su,Guoying Feng,Man Xu,Cunwen Wang,Yanbo Li

Catechol-amine coatings offer versatile routes for surface modifications and nanofiltration (NF) membrane preparations. However, the formation of the selective layer is time-consuming and often deficient, rendering it unsuitable for large-scale applications. In this work, oxidation-induced self-polymerization and catechol-amine chemistry were combined to rapidly construct nanofiltration membranes in an aqueous medium . M -phenylenediamine (MPD) underwent oxidation and self-polymerized on a polysulfone (PSF) support. The addition of sodium periodate facilitated the subsequent tannic acid (TA) coating. The catechol-amine reaction between oxidized TA and poly-MPD forms crosslinked poly TA-MPD complexes, offering the resulting membrane a high selectivity. The role of NaIO 4 in the selective layer formation and the influences of the synthesis parameters on the membrane performance were discussed. Utilizing the facile method enabled the achievement of a low molecular weight cut-off (MWCO) NF membrane (180 Da). The membrane exhibited a high water permeance (10.9 Lm −2 h −1 bar −1 ) and good salt rejections (93 % for Na 2 SO 4 ). The filtration of the bovine serum acid (BSA) solution demonstrated the membrane has good antifouling performance with a flux recovery ratio (FRR) of 95.1 %. The proposed method offers a straightforward and rapid approach to fabricating low MWCO NF membranes in an aqueous medium, which has potential in large-scale applications.

A novel near-infrared AP-M@AntiACLY detection probe based on SERS to trace detection of serum ACLY for early diagnosis of pediatric sepsis

Yilin Zhao,Amin Zhang,Shuyun Feng,Tiantian Liu,Jingjing Ning,Yucai Zhang,Jin Cheng,Qian Zhang,Chunxia Wang

Sepsis is a critical condition characterized by high morbidity and mortality. The development of technologies for early recognition of sepsis is essential for enhancing patient outcomes. Our original finding indicates that ATP-citrate lyase (ACLY) holds promise as a diagnostic biomarker for sepsis; however, sensitive methods for detecting trace levels of ACLY in serum are currently lacking. We have therefore developed a novel AP-M@Anti ACLY detection probe based on surface-enhanced Raman scattering (SERS) for the detection of serum ACLY. The AuNBPs@MBA was synthesized using gold nanobipyramids (AuNBPs) as the base and 4-mercaptobenzoic acid (4-MBA) as a reflective indicator for ACLY activity. Specifically, the Raman signal of 4-MBA decreases proportionally with an increase in ACLY concentration. ACLY antibodies were subsequently linked to AuNBPs@MBA via the gold-sulfur bonds and blocked with bovine serum albumin (BSA). Under optimized conditions, the probe exhibits a strong linear correlation between Raman signal and ACLY concentrations, ranging from 1 pg/mL - 0.5 ng/mL (R 2 = 0.998) and 0.1–500 ng/mL (R 2 = 0.999), with a remarkable limit of detection (LOD) of 1.0 pg/mL. AP-M@Anti ACLY detection probe surpasses enzyme-linked immunosorbent assay (ELISA) when testing septic children's serum samples in terms of its detection range, accuracy, and analysis time. Recovery rates ranged from 96.80 % to 102.52 %. In conclusion, all results suggest that AP-M@Anti ACLY detection probe is a promising tool for the early diagnosis of sepsis and offers new insights into the development of preclinical approaches.

Study on the reaction selectivity and hazard of m-xylene nitration catalyzed by SO3H-functionalized ionic liquids with different anions: Experimental and theoretical approaches

Hang Yao,Jialei Huang,Yuqing Ni,Zhen Cheng,Gang Fu,Lei Ni,Juncheng Jiang,Yong Pan

Five imidazole based SO 3 H-functionalized ionic liquids (SFILs) with different anions were selected as catalysts to achieve efficient m-xylene nitration. The acidity and thermal stability of the ILs were characterized by UV–vis and thermogravimetry. The reaction selectivity of the m-xylene nitration catalyzed by five ILs was compared. [MIMBs]HSO 4 had the best catalytic activity with the maximum yield of 98.1 %. The effect of ILs on the exothermic behavior of m-xylene nitration was explored by reaction calorimeter. The reaction enthalpy (Δ H ) and adiabatic temperature rise (Δ T ad ) were calculated to evaluate process hazards. The reaction order for the decomposition of different nitration products under adiabatic conditions was essentially close to 1. The process risk level for m-xylene nitration with the introduction of selected ILs was essentially downgraded from conditionally acceptable to acceptable, and the criticality was reduced from class 3 to 1. Furthermore, the acidic active sites of the ILs were predicted by the electrostatic potential. The solubility of m-xylene in the IL was investigated through the calculation of interaction energy. The roles of ILs as solvents and catalysts in nitration were resolved by density functional theory calculations. These findings could contribute to the understanding of the effect of ILs in modulating the process hazards and improving the selectivity of m-xylene nitration, and provide theoretical guidance for elucidating the catalytic mechanism of ILs in nitration.

Hypoxia-inducible factor-1 alpha (HIF-1α) inhibitor AMSP-30 m attenuates CCl4-induced liver fibrosis in mice by inhibiting the sonic hedgehog pathway

Lili Lu,Yuchen Ma,Qing Tao,Jing Xie,Xiao Liu,Yongkang Wu,Yang Zhang,Xiuli Xie,Mingming Liu,Yong Jin

Liver fibrosis is a passive and irreversible wound healing process caused by chronic liver injury. Research has shown that the upregulation of hypoxia inducible factor-1 alpha (HIF-1α) is closely related to the occurrence and development of liver fibrosis and HIF-1 α may be a promising target for the treatment of liver fibrosis. AMSP-30 m is a newly developed novel HIF-1α inhibitor by our group, which has strong anti-tumor and anti-inflammatory effects. In this study, we described the therapeutic effect and specific mechanism of AMSP-30 m on carbon tetrachloride (CCl 4 ) induced liver fibrosis in mice. Liver fibrosis induced by CCl 4 in mice and liver fibrosis induced by cobalt dichloride (CoCl 2 ) in LX-2 cells (human hepatic stellate cell (HSC) line) were studied. Hematoxylin & eosin (H&E)and Masson's trichrome staining were used to observe pathological conditions. Western Blot, immunofluorescence and immunohistochemistry were used to detect protein expression and localization in cells, and quantitative real-time PCR analysis (qRT-PCR) was used to detect mRNA expression. Biochemical detection kits were used to detect alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. The results demonstrated that AMSP-30 m significantly alleviated pathological symptoms, reduced ALT and AST levels, and inhibited the expression of alpha-smooth muscle actin (α-SMA) and collagen type I (COL1α1) in CCl 4 -induced liver fibrosis in mice. AMSP-30 m could significantly reduce the expression of HIF-1α and sonic hedgehog (Shh) pathway related proteins (Smoothened (Smo), Shh, and glioma-associated oncogene-1 (Gli-1)) in CCl 4 induced liver fibrosis mice. AMSP-30 m also played a similar role in the CoCl 2 -induced anoxic liver fibrosis model of LX-2 cells . Further experiments showed that Cyclopamine (a Shh inhibitor) could significantly inhibit the increase of α-SMA and COL1α1 resulting from HIF-1α but not significantly inhibit HIF-1α induced by CoCl 2 in LX-2 cells. And the combination of Cyclopamine and AMSP-30 m further reduced the expression of α-SMA and COL1α1 induced by HIF-1α. In summary, this study demonstrates that the HIF-1α inhibitor AMSP-30 m exerts a robust anti-fibrotic effect by inhibiting the Shh pathway, which is identified as a critical underlying mechanism. These findings suggest a promising therapeutic strategy for the treatment of liver fibrosis.

Preparation of BaAl2-xGaxSi2O8:Ce3+, M+ (Li, Na, K) blue-cyan phosphors based on charge compensation and cation substitution strategies and luminescence performance study

Halizati Abulimiti,Aierken Sidike,He Jiuyang

Highly efficient blue-cyan phosphors can fill the cyan gap in conventional white light-emitting diode (LED) devices to improve the spectral continuity while effectively increasing the white LED colour rendering index (Ra). In this study, Ba 0·94 Al 2- x Ga x Si 2 O 8 :0.06Ce 3+ , M + (Li, Na, K, x  = 0–0.8) blue-cyan phosphors with a feldspar structure were prepared by a high-temperature solid-phase method using charge compensation and cation substitution strategies. The barium (Ba) vacancy due to the charge-imbalance substitution of Ce 3+ is compensated by the different charge compensators Li + , Na + , and K + . The charge compensators affect the luminescence performance of the samples, with the K + -compensated samples showing the greatest enhancement, with intensities up to 1.8 times that of the uncompensated samples. The cation substitution strategy using Ga 3+ to partially replace Al 3+ further improves the luminescence performance of the Ba 0·94 Al 2 Si 2 O 8 :0.06Ce 3+ , 0.04 K + sample, and the excitation band is also improved. In this case, the luminescence intensity of the Ba 0·94 Al 2 Si 2 O 8 :0.06Ce 3+ luminescent material is increased by a factor of 6, and a broadband blue-cyan phosphor with a full-width at half-maximum of 118 nm containing blue, cyan and green is obtained. The co-doping of charge compensators and partial cation substitution improved the luminescence performance of phosphors. The representative sample Ba 0·94 Al 1.6 Ga 0.4 Si 2 O 8 :0.06Ce 3+ , 0.04 K + has a luminescence intensity at a temperature of 150 °C that is 83.2% of that at room temperature and good thermal stability . The combination of 365 nm near-ultraviolet (NUV) LED chips with Ba 0·94 Al 1.6 Ga 0.4 Si 2 O 8 :0.06Ce 3+ , 0.04 K + and the commercial red powder (Ca, Sr)AlSiN 3 :Eu 2+ yields a white LED device with an Ra of up to 93 and a correlated colour temperature (CCT) of 4825 K. These results show that the blue-cyan phosphor complements the cyan component while simplifying the manufacturing process of white LEDs.

Iron/silicon oxy-hydroxide co-precipitate trace-incorporated [-Fe-O]m-[Si-O-]n colloids: A facile strategy for silica xerogel strengthening and toughening

Chengdong Li,Yuxiang Wang

Significant volume shrinkage during the ambient pressure drying is a common defect in the synthesis of silica xerogels, leading to densification, collapse of pore structure, and a decline in mechanical properties. Conventional methods struggle to produce silica xerogels with both low bulk density and high mechanical properties without additional post-treatment. Herein, we introduce a novel approach by ultilizing trace amounts of iron/silicon oxy-hydroxide co-precipitate trace-incorporated [-Fe-O] m -[Si-O-] n colloids as the foundational building blocks for polymethylsilsesquioxane (PMSQ) xerogels. These colloids were synthesized through the condensation of hydrated iron cations with methyltriethoxysilane (MTES) hydrolysates, which also influence the aggregation and sedimentation of MTES sols. The impact of the hydrolysis time of MTES on the chemical compositions, phase structures, microstructures of the iron/silicon oxy-hydroxide co-precipitates, and mechanical properties of PMSQ xerogels were investigated. The optimal hydrolysis time of MTES in the cetyltrimethylammonium bromide/ferric chloride (CTAB/FeCl 3 ) aqueous solution was 5.0 h, endowing MTES sols containing a trace of ∼0.046 mg/mL iron/silicon oxy-hydroxide co-precipitates. This process yielded PMSQ xerogels with a high compression strength of 0.316 MPa and maximum compression strain of 79.3 %. Deviating from this optimal hydrolysis time by 1.0 h might significantly reduce the compression strength of the as-synthesized PMSQ xerogels by 18.0 %-58.5 % and decrease the maximum compression strain by 6.6 %-15.4 %. Notably, the tiny incorporation of the iron phase (∼0.1 mol%) into the Si-O-Si backbone endowed the PMSQ xerogels with a minimal volume shrinkage ratio of 5.5 %, an ultra-low bulk density of 69.8 mg/cm 3 , and the highest specific strength of 4.527 kPa·m 3 /kg recorded among all aerogels and xerogels in the literature. The strategy of forming iron/silicon oxy-hydroxide co-precipitates to strengthen and toughen silica xerogels by modulating the hydrolysis/condensation kinetics of hydrated iron cations and silica sources holds promise for maximizing mechanical properties and minimizing bulk density under industrially relevant conditions.

A G2/M-phase specific drug delivery system based on increased exposure of phosphatidylethanolamine on mitotic cancer cells and low pH in tumor tissues

Wenxiu Hong,Siyu Guan,Qianqian Zhang,Jianwei Bao,Haoran Dai,Lele Liu,Wenqiang Li,Weichao Kong,Rongfeng Hu,Jihui Tang

It is a challenge to carry G2/M-phase specific antitumor drugs into G2/M phase of cancer cells. For this purpose, we set up a pH-sensitive mixed micellar system based on poly(ethylene glycol)-b-poly( l -histidine) (PEG-PHIS) and poly(ethylene glycol)-b-poly(D, l -lactide) (PEG-PDLLA), and we used duramycin , a highly specific phosphatidylethanolamine-binding peptide, as a G2/M-phase specific targeting ligand to modify PEG-PDLLA. The mixed micelles were characterized by dynamic light scattering , electron microscopy and the pyrene fluorescence probe method. The G2/M-phase specific anti-cancer drug paclitaxel was loaded with a size of 189 ± 5  nm . And the drug-loading content and encapsulation efficiency were 14.7 ± 0.3% and 89.1 ± 2.5%, respectively. In addition, cytotoxicity assay showed that paclitaxel-loaded mixed micelles had effective antitumor effects, and the blank mixed micelles were safe. Importantly, the micelles showed pH sensitivity and G2/M-phase specific uptake. What's more, pharmacokinetic and in vivo imaging study showed that the mixed micelles displayed a prolonged circulation time and improved targeted accumulation at tumor sites. All these results suggest that the mixed micelle was a promising G2/M-phase specific drug delivery system .

Livistona Chinensis leaf as bioorganic frame for porous carbon support and metal corrolate as M-N-C active site to construct oxygen reduction reaction electrocatalyst

Yun-Rui Lv,Jia-Hui Zhang,Kun Fang,Duo-Duo Liu,Nan Li,Li-Ping Si,Hai-Yang Liu

Achieving low-cost and scalable fabrication of oxygen reduction reaction (ORR) catalysts remains one of the central challenges for the commercialization of high-performance energy conversion devices. In this work, Livistona chinensis leaves (LCL) are used as the sustainable bioorganic frame (BOF) precursor for constructing the carbon material LCLC. After doping transition metal (Fe, Co, Mn) 1, 10, 15-tris(pentafluorophenyl)corrole (TPFC) complexes and followed by pyrolysis, the carbon based ORR electrocatalysts MTPFC/LCLC bearing the metal-nitrogen-carbon (M-N-C) active site were prepared. Of all prepared MTPFC/LCLC, the iron corrole doped carbon material FeTPFC/LCLC exhibited the best electrocatalytic ORR activity, featuring a half-wave potential ( E 1/2 ) of 0.877 V (Vs the reversible hydrogen electrode, RHE). The constructed zinc-air battery (ZAB) by using FeTPFC/LCLC cathode achieved an open-circuit voltage of 1.48 V and a specific capacity of 809.9 mAh g -1 (based on consumed Zn), both surpassing the commercial Pt/C catalyst. Our work proved the tremendous potential of Bioorganic frame derived carbon and metal corrolates for practical ORR catalysts.

Effect of polyethylene glycol on corrosion of fresh macroporous silicon in 1.0 M NaOH and application in determination of porosity and thickness by gravimetric measurement

Chuan Lai,Xiaogang Guo,Mingfeng Wang,Jiajun He,Zhuli Wang,Bin Xie

Dry reforming of methane over Co-Ce-M/AC-N catalyst: Effect of promoters (Ca and Mg) and preparation method on catalytic activity and stability

Yinghui Sun,Guojie Zhang,Ying Xu,Riguang Zhang

The catalytic activity of DRM reaction over 1M-1Co-1Ce/AC-N (M = Ca and Mg) catalysts was investigated at 800 °C and under atmospheric pressure. By promoting N-doped activated carbon supported Co-Ce catalysts with alkaline-earth metals to obtain catalysts with better catalytic performance is the main purpose of study. The catalysts were prepared by wet-impregnation method and the influence of impregnation sequence on catalytic performance was also studied. The characterization was conducted using TPR, TPD , XPS, TEM and Raman. The catalyst 1Ca-1Co-1Ce/AC-N promoted with Ca and prepared by co-impregnation exhibited higher catalytic activity than unmodified. This was mainly due to the stronger interaction between metal and support as well as better active metals dispersion. The 1Ca-1Co-1Ce/AC-N catalysts also displayed excellent stability and XPS results indicated that higher Ce 3+ /Ce 4+ and O β /(O α +O β ) ratios were observed on this catalyst. However, the catalyst 1Co-1Ce/1Ca/AC-N prepared with sequential impregnation exhibited poor stability. In addition, the TEM of the spent catalysts revealed that there were a large number of carbons were generated on active metal surface.

Phase Equilibrium of the RbCl–RbBr–H2O System at 298.15 K and Molecular Dynamics Simulations of MCl–MBr–H2O (M = Li+, Na+, K+, Rb+, NH4+)

Ya-Li Wang,Rui-Zhi Cui,Hong-Bao Ren,Qiu-Ye Yang,Wu Li

This study addresses the unclear crystallization behavior of rubidium in chlorobromine coexisting brine systems through experimental and simulation approaches. First, the phase equilibrium data of the ternary system RbCl–RbBr–H2O at 298.15 K were determined using the isothermal dissolution equilibrium method, and the corresponding phase diagram was constructed. The solid phase was characterized by XRD and SEM-EDS, and solubility was theoretically calculated and validated using the Pitzer model. To further elucidate the solid-solution formation behavior of rubidium in chlorobromine coexisting brine systems at the microscopic level, molecular dynamics simulations were performed. Combined with the previously reported phase diagrams of MCl–MBr–H2O systems (M = Li+, Na+, K+, NH4+), the radial distribution functions, coordination numbers, and mean square displacements of different systems were systematically analyzed to examine the differences in ionic hydration structures and migration behavior. From macroscopic phase equilibria to microscopic ion dynamics, this study systematically clarifies the common patterns of formation of continuous solid solutions in chlorobromine coexisting brine systems.