ACS Sustainable Chemistry & Engineering
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2025
·
IF 7.3
Yi Ma,Huan Ge,Yong Zhang,Ning Jian,Jing Yu,Jordi Arbiol,Canhuang Li,Yue Zhong,Luming Li,Hui Kang,Jun Wang,Andreu Cabot,Junshan Li
The electrocatalytic oxidation of small organic molecules, such as ethylene glycol (EG), can be paired with the hydrogen evolution reaction (HER) to effectively lower the overall cell voltage, thereby enhancing energy efficiency for hydrogen production. Moreover, the anodic EG oxidation reaction (EGOR) can generate valuable C1 and C2 compounds, offering a sustainable approach to greener chemical production. The industrial viability of this process requires nonprecious metal electrocatalysts that demonstrate high performance at low potential and exhibit high selectivity. In this study, we report on a cost-effective electrocatalyst based on a nickel sulfide phase (Ni3S2) heterogeneously nucleated on the surface of nickel–iron-manganese layered double hydroxide (NiFeMn-LDH) nanosheet arrays and supported on nickel foam (NF), demonstrating exceptional activity for the coupled HER and EGOR in alkaline conditions. This Ni3S2@NiFeMn-LDH/NF catalyst achieves an EG-to-formate faradaic efficiency of up to 90% at 1.5 V, with glycolate and oxalate as minor byproducts. Density functional theory calculations reveal that the EGOR was facilitated by the phase-separated Ni3S2, which lowers the energy barrier of the rate-limiting step. This work presents a promising, sustainable pathway for hydrogen production alongside value-added chemical generation from the electrooxidation of EG.
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MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2025
·
IF 2.7
Yunhui Cai,Yixiang Chen,Lijun Fan,Xianhong Zhang,Wantai Yang
Herein, two categories and four kinds of novel eco-friendly plasticizers, cyclohexanecarboxylic acid-based methoxypolyethylene glycols (H-MPEG200 and H-MPEG400) and cyclohexanecarboxylic acid-based polyethylene glycol (H-PEG200 and H-PEG400), are synthesized via the esterification reaction. Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (1H NMR) certified the successful synthesis of precise target structure. Thermogravimetric analysis (TGA) results revealed that both H-MPEG and H-PEG have better thermal stability than dioctyl phthalate (DOP). Subsequently, the plasticization efficiency of H-MPEG and H-PEG is investigated systematically by replacing a portion of DOP in a soft poly(vinyl chloride) (PVC) system. The rheological results indicated that the fusion time, fusion torque, and equilibrium torque of PVC blends have a slight decrease in comparison to that of DOP at a similar content of total plasticizer. The TGA analysis demonstrated the PVC films plasticized with H-PEG400 or H-MPEG exhibited better thermal stability than other plasticizers. Among them, H-MPEG has higher plasticizing efficiency than DOP, in which the glass transition temperature ( T g ) is −2.34 °C for PVC/H-MPEG200 and −6.27 °C for PVC/H-MPEG400, respectively. Meanwhile, the H-PEG and H-MPEG showed outstanding compatibility with the PVC matrix, endowing the PVC blends with high transmittance.
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ACS Biomaterials Science & Engineering
·
2025
·
IF 5.5
Xiaojuan Chen,Bojia Li,Bin Zhou,Bin Li,Hongshan Liang
Bioactive components, especially hydrophobic functional molecules, have inspired various nanobiotechnology approaches to stabilize and further realize their biological functions, particularly in vivo delivery. Desirable features of a delivery system for functional molecules should possess high biocompatibility, favorable encapsulation capacity, and simple fabrication processes without requiring chemical modification of the molecule itself. Herein, we report a facile and low-cost approach, based on tannic acid–polyethylene glycol (TA–PEG)-mediated assembly, for assembling citrus-derived nobiletin into nanoparticles (i.e., NTP NPs) under aqueous conditions. The resulting multifunctional spherical NPs with long-term stability and desirable encapsulation efficacy are mostly facilitated by hydrogen bonding and π interactions, as confirmed by in-depth spectroscopic analyses. Incorporating fluorophores into NTP NPs enables the visualization of intracellular transport and biodistribution at different time points, revealing that most of these NPs achieved enhanced cellular uptake and transport efficiency and prolonged intestinal retention, comparable to that of free nobiletin. This work provides a viable strategy for the rational design of hydrophobic functional molecule nanoparticle delivery platforms tailored for diverse biological applications.
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PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Haotian Tang,Mengwei Guo,Rongrong Deng,Mingyuan Gao,Qibo Zhang
This study investigates the electrorefining of zinc derived from hot-dip galvanizing (HDG) slag, employing a deep eutectic solvent (DES) composed of choline chloride and ethylene glycol, commonly referred to as Ethaline DES. A thorough electrochemical analysis was carried out to examine the oxidative dissolution behaviors of metallic zinc and associated impurity metals, along with the reduction behavior of Zn(II) ions. These findings demonstrate that, in the Ethaline-ZnCl 2 DES system, zinc undergoes oxidation preferentially compared to impurities, enabling selective extraction of zinc from HDG slag. Furthermore, the reduction potential of Zn(II) is observed to be more positive than that of the impurity metal ions, favoring its preferential deposition at the cathode. Increasing the temperature and incorporating an appropriate quantity of water significantly reduce the viscosity and improve conductivity of the Ethaline DES system, thereby enhancing charge transfer and diffusion of Zn(II) ions while lowering the energy barrier for Zn(II) reduction. Under optimized electrorefining conditions, the resulting cathodic zinc achieves a purity of 99.967 %, with a current efficiency of 95.14 % and an energy consumption of 787 ± 26 kWh/t. This work proposes a sustainable and energy-efficient method for the electrorefining of zinc from HDG slag, presenting a viable pathway for the valorization of this metallurgical byproduct.
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高影响因子
BIOSENSORS & BIOELECTRONICS
·
2016
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IF 7.476
Min Cui,Zhiling Song,Yumin Wu,Bing Guo,Xiaojian Fan,Xiliang Luo
Biocompatible polymers, such as poly(ethylene glycol) (PEG), are of great significance in the development of bio-interfaces and biosensors, as they possess excellent biocompatibility and are easy for modification. A novel highly biocompatible polymer composite was synthesized herein through electrochemical polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) and a PEG derivative, 4-arm PEG terminated with thiol groups . The electrodeposited conducting polymer composite of PEG doped PEDOT (PEDOT/PEG) exhibited flake-like nanostructure , large surface area and outstanding stability. In order to further immobilize antibodies, gold nanoparticles (AuNPs) were introduced to the PEDOT/PEG composite surface through their unique interaction with the thiol groups . AuNPs modified PEDOT/PEG provided a desirable support for the immobilization of various biomolecules such as antibodies for alpha fetoprotein (AFP), a vital tumor biomarker for liver cancer. The fabricated AFP biosensor demonstrated favorable selectivity, high sensitivity, and ultralow detection limit. Furthermore, owing to the presence of PEG polymers that are highly hydrophilic , such AuNPs/PEDOT/PEG based AFP biosensor also exhibited good anti-fouling ability, and it was capable of assaying target AFP in 10% (V/V) human serum samples, indicating highly feasible potential for clinical diagnosis.
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高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2019
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IF 2.29
Hui Guo,Xiaoqin Shi,Shufeng Shen
Non-aqueous mixtures of monoethanolamine (MEA) with glycol ethers as low viscosity absorbents have potential advantages for CO 2 capture. In this work, physical solubility of N 2 O and CO 2 in glycol ethers (2-methoxyethanol and 2-ethoxyethanol) and their blends with MEA was measured and correlated at temperatures ranging from (293.15 to 333.15) K. Physical solubility of CO 2 in the blends was also estimated by N 2 O/CO 2 analogy method. A mathematic model based on the reaction mechanism was proposed to interpret the vapour-liquid equilibrium data for the systems of CO 2 /MEA/glycol ether solution. Results show that glycol ethers have greater ability to dissolve CO 2 than glycols and water. The apparent chemical equilibrium constant was obtained and correlated as a function of temperature by non-linear regression. The proposed model could reasonably fit the experimental data with an average absolute deviation within 10%. The heat of absorption of CO 2 in MEA/glycol ether systems was also calculated.
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高影响因子
Polymers
·
2021
·Vol. 13
·期 15
·2388
·
IF 4.329
Meina Xie,Daikun Jia,Jin Hu,Jiyu He,Xiangmei Li,Rongjie Yang
In this study, the aromatic acetylene compound 4-(phenylethynyl) di(ethylene glycol) phthalate (PEPE) was used as a chain extender, partially replacing 1,4-butanediol. To synthesize an intrinsic flame-retardant thermoplastic polyurethane elastomer (TPU) with an aromatic acetylene structure, PEPE was synthesized by a two-step polymerization. The flame retardancy, thermal stability, and mechanical properties of TPU were studied. The microstructure of TPU char was investigated by scanning electron microscopy to analyze the flame-retardant mechanism. The tensile strength of TPU containing 1.35 wt% PEPE was 39.2 MPa, which was almost twice as much as neat TPU, showed a dramatic decrease in the peak heat release rate and total heat release, and declined by 46.2% and 24.5%, respectively. After the flame-retardant TPU burned, a cross-linked network foaming char structure was formed. The results showed that PEPE improved the mechanical properties of TPU and conferred good stability that promoted the formation of charcoal and reduced heat release during the combustion of TPU.
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高影响因子
Science China-Materials
·
2020
·Vol. 63
·期 9
·1731-1740
·
IF 6.098
Zhan Changhong,Yu Zijia,Liu Zheng,Chen Yong,Chen Delun,Tu Jinchun,Wu Qiang,Zhang Xiaolin,Cao Yang
As a half-reaction to obtain high-efficiency and stable water-splitting, oxygen evolution reaction (OER) is a slow-kinetics process involving a four-electron (4e - ) transfer process and therefore requires catalysts to fasten electron transfer. Here, we rationally optimized an interface material of ceria nanoparticles and nickel hydroxide by adsorbing ethylene glycol (EG-Ni(OH) 2 @CeO 2 ), which produced ultrasmall nanosheets uniformly attached onto carbon cloth substrate. According to the characterization and density functional theory (DFT), the ethylene glycol-induced nickel-cerium interface had strong electron interaction, generating numerous of Ni (3-δ)+ active sites, reducing the energy reaction barrier, and promoting the electron-transport kinetics in the catalytic system. EG-Ni(OH) 2 @CeO 2 showed excellent OER performance, with a low overpotential (335 mV) at 50 mA cm -2 and a small Tafel slope (67.4 mV dec -1 ). And the EG-Ni(OH) 2 @CeO 2 also maintained stable for up to 60 h at 10, 20, and 30 mA cm -2 . Overall, this research shows the significance of the interface engineering of metal materials based on organic-solvent adsorption to improve the electrocatalytic OER process.
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高影响因子
CELLULOSE
·
2024
·
IF 4.9
Tang Ruihua,Yan Xueyan,Hu Jie,Luo Yining,Giesy John P.,Xie Yuwei,Yin Huancai
Rapid nucleic acid testing (NAT) technology as an effective tool for point-of-care testing (POCT), has been widely used for health, food additive, and environmental pollution monitoring. Nucleic acid extraction (NAE) is a vital first step of NAT technology, including sample lysis, washing and elution. At present, storage of sample lysis solution for rapid NAE methods is expensive, complex and environmentally unfriendly. To address these drawbacks, a low-cost, rapid, simple, and portable material is urgently needed. Herein, we developed a pH-responsive carboxymethyl chitosan/sodium alginate/polyethylene glycol (CMCS/SA/PEG) composite hydrogel that works as a physical crosslink, then used it to store sample lysis solutions for the dry immersion method for NAE. Results showed that the CMCS/SA/PEG6000 composite hydrogel had large pore size (256.58 ± 5.58 μm), good wet strength (282.3 Kpa), excellent swelling rate (706.91 ± 6.69%), high loading capacity (90.46 ± 1.13%), good degradation capacity (77.87 ± 1.45%), and rapid response time (15 s). The CMCS/SA/PEG6000 composite hydrogel could be loaded into a syringe and combined with filter paper to function as a simple NAE device. Efficiency of lysis of nucleic acid of saliva, whole blood, E.coli and S.aureus was 20.71 ± 0.12%, 9.59 ± 0.12%, 16.57 ± 0.19%, and 29.16 ± 0.07%, respectively. Also, nucleic acid was successfully extracted from a 30 μL sample of saliva so the method has potential to be integrated into other platforms for NAT.
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PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
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2020
·
IF 2.169
Yutong Wang,Yanfang Ding,Changyuan Wang,Meng Gao,Youwei Xu,Xiaodong Ma,Xinyi Ma,Hongxia Cui,Lei Li
Fenretinide (4-HPR), a synthetic retinoid, has shown its antitumor activity in many tumor types with low cytotoxicity to normal cells and high clinical safety. However, the low water solubility limits its further biological applications. To increase solubility, 4-HPR was conjugated with methoxy polyethylene glycol carboxylic acid (mPEG2K-COOH) by an ester linkage between the phenol hydroxyl of 4-HPR and the carboxyl of mPEG2K-COOH. The 4-HPR-PEG2K conjugate micelles had mean size of 76.70 ± 1.248 nm with a narrow distribution and a low critical micelle concentration. In vitro cytotoxicity studies showed the micelles have higher cytotoxicity to A2780s and MCF-7 cells. Its IC50 was 4.7 and 4.1-fold lower than the free 4-HPR, respectively. Importantly, in vivo pharmacokinetic studies, the AUC of 4-HPR was found to be 2.3-fold higher in 4-HPR-PEG2K micelles compared to free 4-HPR. And the 4-HPR-PEG2K micelles had higher antitumor activity. Meanwhile, the histopathology analysis exhibited that the micellar treatment decreased the viability of A2780s cells and increased the level of induced apoptosis. Therefore, the enhanced activity of 4-HPR by the method of conjugation with mPEG2K-COOH could hopefully provide new insights into the matter of ovarian cancer and breast cancer treatment.
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PubMed
高影响因子
Polymers
·
2024
·Vol. 16
·期 24
·3516
·
IF 4.7
Jia Li,Shu Li,Aozhen Zhong,Jun Xing,Ling Li,Cai Wang,Min Zheng
Powder-based hemostatic materials have offered unprecedented opportunities for the effective sealing and repair of irregularly shaped wounds and high-pressure, noncompressible arterial bleeding wounds caused by surgeries, traffic accidents, and wartime injuries. However, inadequate adhesion to bleeding wounds and poor hemostasis in biological tissues remains challenging. Herein, we report a self-gelling hemostatic powder based on polyacrylic acid/polyethyleneimine/polyethylene glycol (named PPG) for rapid hemostasis and effective antibacterial ability. When deposited on bleeding wounds, PPG powder can absorb interfacial liquid and rapidly swell into a physically cross-linked hydrogel in situ within 2 s to form a pressure-resistant physical barrier. Furthermore, the in vivo and in vitro results indicate that, as an effective sealant, the PPG powder possesses ease of use, excellent hemocompatibility, strong antibacterial abilities, and superior blood clotting abilities. The effective hemostatic sealing capability of the PPG powder is demonstrated in a variety of injury models in rats and rabbits. All of these factors show that, with its superior wound treatment abilities, PPG powder is a profound biomaterial for surgical applications.
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ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Zelun Zhi,Yajuan Su,Yuewei Xi,Liang Tian,Miao Xu,Qianqian Wang,Sara Padidan,Peng Li,Wei Huang
In recent years, microbial colonization on the surface of biomedical implants/devices has become a severe threat to human health. Herein, surface-immobilized guanidine derivative block copolymers create an antimicrobial and antifouling dual-functional coating. We report the preparation of an antimicrobial and antifouling block copolymer by the conjugation of polyhexanide (PHMB) with either allyl glycidyl ether or allyloxy polyethylene glycol (APEG; MW 1200 and 2400). The allyl glycidyl ether modified PHMB (A-PHMB) and allyloxy polyethylene glycol1200/2400 modified PHMB (APEG1200/2400-PHMB) copolymers were grafted onto a silicone rubber surface as a bottlebrush-like coating, respectively, using a plasma-UV-assisted surface-initiated polymerization. Both A-PHMB and APEG1200/2400-PHMB coatings exhibited excellent broad-spectrum antimicrobial properties against Gram-negative/positive bacteria and fungi. The APEG2400-PHMB coating displayed an improved antibiofilm as well as antifouling properties and a long reusable cycle, compared with two other coatings, due to its abundant PEG blocks among those copolymers. Also, the APEG2400-PHMB-coated silicone coupons were biocompatible toward mammalian cells, as revealed by in vitro hemocompatibile and cytotoxic assays. An in vivo study showed a significant decline of Escherichia coli colonies with a 5-log reduction, indicating the APEG2400-PHMB coating surface worked effectively in the rodent subcutaneous infection model. This PHMB-based block copolymer coating is believed to be an effective strategy to prevent biomaterial-associated infections.
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高影响因子
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