Journal of Materials Chemistry A
·
2014
·Vol. 2
·期 37
·15495-15501
·
IF 0
Guangdi Nie,Xiaofeng Lu,Junyu Lei,Ziqiao Jiang,Ce Wang
V2O5-doped α-Fe2O3 composite nanotubes have been successfully fabricated via a simple one-step electrospinning technique followed by calcination treatment. For the first time, we found that the magnetic properties of the as-prepared samples were significantly dependent on the contents of the dopant. In comparison with pristine α-Fe2O3, perfect reversibility, more excellent capacitance and better cycling stability were simultaneously observed for the hybrid metal oxide with an appropriate mass ratio of V2O5 (VFNT1) when it was utilized for supercapacitor electrodes, indicating that the doped α-Fe2O3 tubular nanostructures are fairly promising for practical applications not only in magnetic recording but also in the energy storage field.
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JOURNAL OF PHYSICAL CHEMISTRY B
·
2014
·
IF 3.377
Long Huang,Lili Zhang,Xinan Huang,Tao Li,Bo Liu,Dan Lu
In this work, the α-conformation (individual locally separated chain) of the conjugated polymer poly(9,9-dioctylfluorene) (PFO) in dilute solution is studied by the following three points: the Mark–Houwink exponent a, the fractal dimension D, and the form factor Rg/Rh. From the result of a, the α-conformation of PFO is considered to have a semirigid chain conformation in dilute solution. We establish the mathematical relationship between the Mark–Houwink exponent a and the fractal dimension D in dilute solution. To prove the rationality of this mathematical relationship, the classic polymer polystyrene (PS) is used for comparison. According to the result of D, it can be known that the α-conformation of PFO has a relatively loose and extended chain conformation. Moreover, we use light scattering to get the form factor Rg/Rh of the PFO solution in which the α-conformation and β-conformation coexist. It is found that Rg/Rh increases with the proportion of α-conformation, which indicates that the α-conformation of PFO has a loose and extended chain conformation, and this result agrees well with the conclusions drawn from a and D. On the basis of the fact that the β-conformation (ordered conformation) and α-conformation of PFO can transform into each other in solution, this work is significant for the control of the β-conformation and will have a potential meaning to increase the charge carrier mobility and efficiency from the PFO solution to films.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
He Xu,Yanhao Hu,Mian Wei,Jiahao Wang,Enpei Zhang,Dechao Gu,Chengyu Liu,Jiajun Huang,Youmei Ma,Wei Yan,Jiahai Zhou,Yonghao Ye,He Bo
Dihydroxy acid dehydratase (DHAD) is a promising herbicide target, but no commercial DHAD inhibitors exist yet. The natural product aspterric acid (AA) has been shown to act on DHAD, inspiring us to discover novel cycloheptanone-pyrrole compounds (6aa-6ay) featuring α-hydroxycarboxylate fragments as potential DHAD-targeting herbicides. In Arabidopsis thaliana seed germination assays, most compounds demonstrated 100% inhibition at 200 μg/mL, comparable to that of the positive control penoxsulam. In greenhouse herbicidal activity tests, compound 6ag demonstrated over 85% control effectiveness against Eclipta prostrata, Amaranthus retroflexus, and Setaria viridis at a dosage of 150 g ai/ha, while also showing safety for rice. The binding model of 6ag with DHAD is similar to that of AA with DHAD, and the Kd value of 6ag binding to DHAD is 20 μM, indicating that 6ag acts with DHAD. With both herbicidal efficacy and crop safety, 6ag represents a promising novel lead compound for DHAD inhibitors.
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INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
·
2026
·Vol. 57
·期 4
·1-13
·
IF 8.5
Peng-Yao Lin,Jia-Rong Xie,Tian-Chen Qian,Shi-Song Wang,Si-Yi Yu,Wen-Bo Shi,Ying Wang,Lu-Ze Cen,Qing-Jing Zhu,Yi-Yang Zheng,Hui Gao,Rong Fang,Zhao-Xia Xia,Ai-Ming Liu,Lei Xu
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.5
Guangai Sun,Shijie Guo,Yuanyuan Yao,Zeyu Lin,Hui Gao,Roland H. Stauber,Bin-Chun Li,Guo-Bin Ding
α-L-Rhamnosidase is a significant biocatalyst that specifically cleaves terminal α-L-rhamnose group from natural flavonoid diglycosides, enabling the biocatalytic production of high-value flavonoid glucosides like prunin from naringin. Compared to its precursor naringin, prunin exhibits superior solubility and bioavailability, making this enzymatic conversion commercially valuable for the food and pharmaceutical industry. However, the industrial application of free α-L-rhamnosidases faces significant challenges, including enzyme instability, difficulty in recovery, and unsatisfactory reusability. To address these issues, this study developed an innovative magnetically recoverable biocatalyst (Fe₃O₄-Rha) through covalent immobilization of recombinant α-L-rhamnosidase from human fecal metagenome onto Fe₃O₄ nanoparticles using EDC/NHS chemistry, and the immobilization parameters were systematically optimized. The successful preparation of Fe₃O₄-Rha was verified by TEM, FTIR, TGA, and SQUID analysis. Fe₃O₄-Rha retained the catalytic property of free Rha in terms of optimal pH and temperature but exhibited superior tolerance on organic solvent especially ethanol and isopropanol. Moreover, Fe₃O₄-Rha could effectively biotransform naringin to prunin and maintained 61.34% of initial activity after 5 cycles. In a scaled-up reaction system, Fe₃O₄-Rha also efficiently converted naringin into prunin and the complete conversion was achieved within 10 h. This work successfully developed a magnetically recoverable immobilized α-L-rhamnosidase system for the efficient and reusable biotransformation of naringin, offering a promising approach for the enzymatic modification of bioactive small molecules using biological macromolecular catalysts.
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FOOD CHEMISTRY
·
2026
·
IF 9.8
Qin Zhou,Yushi Wei,Yijing Liao,Deming Gong,Guowen Zhang
This study investigated the inhibitory effect of vitamin B6 (VB6) on α-glucosidase (Glu) and its synergistic inhibition mechanism with liquiritigenin (LTG). VB6 was identified as a weak mixed-type inhibitor of α-Glu (IC 50 = 2.76 ± 0.95 mM). VB6 quenched the endogenous fluorescence mainly through hydrogen bonding, reducing surface hydrophobicity and loosening the structure of α-Glu. Furthermore, the combination of 6 μM LTG and 0.5 mM VB6 produced the strongest synergistic inhibition on α-Glu without changing the mixed-inhibition pattern. Computer simulation results showed that VB6 reversibly occupied the allosteric cavity of α-Glu, causing structural rearrangements and conformational changes, which allowed LTG to penetrate deeper into the active center, forming hydrogen bonds with the residues Asp69, Asp352 and Arg442, thereby enhancing LTG's binding affinity and inhibitory effect. These findings provided the potential of VB6 in enhancing LTG's anti-α-Glu activity and a basis for the formulation design of hypoglycemic functional food.
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FOOD CHEMISTRY
·
2026
·
IF 9.8
Naymul Karim,Ke Zhang,Mohammad Rezaul Islam Shishir,Mohammad Nasiruddin Rana,Gobinath Marappan,Muhammad Arslan,Haroon Elrasheid Tahir,Li Zhihua,Xiaodong Zhai,Isam A. Mohamed Ahmed,Jitbanjong Tangpong,Xiaobo Zou
α-mangostin (αM), a poorly soluble xanthone, was encapsulated in cocoa butter emulsions stabilized by xanthan gum (XG; 0–0.5%) to enhance its stability and control its gastrointestinal release. The emulsions exhibited high encapsulation efficiency (77–85%) with submicron droplet sizes (440–540 nm), low polydispersity index (<0.3), and negative zeta potential (> −20 mV). Increasing XG concentration enhanced viscosity, shear-thinning behavior, centrifugal stability, and thermal resistance, while ensuring excellent stability over 21 days of storage without oxidative/microbial degradation. Structural analyses (FTIR, XRD) confirmed successful αM encapsulation in a semi-crystalline matrix (crystallinity >60%). Microscopy (CLSM, FESEM) revealed near-spherical droplets with reduced porosity. During simulated digestion, XG-stabilized emulsions provided concentration-dependent control over droplet behavior, αM bioaccessibility, and antioxidant retention, attributed to increased aqueous-phase viscosity and steric hindrance. These findings establish xanthan gum-stabilized cocoa butter emulsions as a promising vehicle for enhancing the stability and controlled intestinal delivery of hydrophobic bioactives like αM.
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Inorganic Chemistry Frontiers
·
2026
·
IF 6.4
Qianwei Li,Daoqing Liu,Wei Yan,Hao Liu,Chunmao Chen
Oxygen vacancies (OVs) play a critical role in enhancing the catalytic performance of transition-metal oxides in advanced oxidation processes (AOPs). However, the effect of OVs on the activation of different persulfates, peroxymonosulfate (PMS) and peroxydisulfate (PDS), is still not well understood. Here, we employ ultrasonic defect engineering to adjust the OV content of α-MnO2 and systematically benchmark its activation of PMS and PDS. XPS, EPR, and electrochemical analyses revealed that the ultrasound-treated α-MnO2 exhibited a significantly increased proportion of Mn(III) and a markedly higher OV concentration, thereby creating densely populated redox-active sites for persulfate adsorption and electron transfer. Mechanistic investigations indicated that in the PMS system, the oxidation pathway was closely associated with OVs: at low OV densities, radical oxidation (SO4˙−/˙OH) predominates, whereas at high OV densities, a non-radical route dominated by singlet oxygen (1O2) prevails. In contrast, the oxidation pathway in the PDS system exhibited a weak correlation with OV content, implicating distinct adsorption/activation motifs for PMS versus PDS on α-MnO2. Radical scavenging experiments and EPR analyses provided supportive, semi-quantitative evidence for these mechanistic trends, within the acknowledged limitations of current ROS identification methods. Collectively, this work establishes a clear structure–reactivity correlation and provides a defect-engineering blueprint for tailoring targeted reactive oxygen species in water purification applications.
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JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
·
2015
·
IF 3.615
Lian-wei Shan,Gui-lin Wang,Li-zhu Liu,Ze Wu
In order to develop low-cost photocatalyst, commercial Bi 2 O 3 was utilized as raw material to prepare α-Bi 2 O 3 /BiOCl core-shell heterojunction via a facile in situ chemical transformation method. To clarify experimentally the band alignment relationships between the α-Bi 2 O 3 and BiOCl (0 0 1), the α-Bi 2 O 3 /BiOCl (0 0 1) core–shell heterojunction band offsets were analyzed by X-ray photoelectron spectroscopy (XPS). Here based on energy gaps, valence band values of α-Bi 2 O 3 and BiOCl (0 0 1), core levels difference of Bi 4f in α-Bi 2 O 3 /BiOCl (0 0 1) heterojunction , we demonstrate that band alignment of ∼0.28 eV exists between α-Bi 2 O 3 and BiOCl with α-Bi 2 O 3 possessing the higher valence band potential or electron affinity which is a driving force of valence band holes from α-Bi 2 O 3 to BiOCl (0 0 1). While, the electrons in conduction band were driven to migrate through conduction band potential difference (0.49 eV) from BiOCl (0 0 1) to α-Bi 2 O 3 .
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Results in Physics
·
2023
·
IF 5.3
Meijie Zhu,Hua Xu,Zuoquan Tan,Le Wang
Large-area and uniform two-dimensional (2D) non-layered α-MnSe was successfully synthesized via the molecular sieve modified chemical vapor deposition (CVD). The molecular sieve serves both as a filter and a container to controllable release the Mn precursor in a stable and much lower concentration, leading to the uniform growth of 2D α-MnSe flakes. The thickness, crystalline quality and uniformity of the as-grown α-MnSe are further characterized. Our study validated the positive role of molecular sieve in the controllable growth of 2D α-MnSe, which is believed to be applicable to other non-layered transition metal chalcogenides (TMCs) and will be beneficial for their further applications in electronics, optoelectronics and spintronics.
研究领域:
材料科学
·
纳米科技
·
凝聚态物理
·
无机化学
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JOURNAL OF ORGANIC CHEMISTRY
·
2019
·
IF 4.745
Yu Shangguan,Fazhou Yang,Hao Deng,Hao Liu,Ziyan Liu,Wanyue Zhuang,Chenxi Qiao,Aizheng Wang,Yumei Xiao,Cheng Zhang
A copper-catalyzed three-component difunctionalization of aromatic alkenes to access 1,4-naphthoquinone derivatives with diverse structures is described. Experiments show that the difunctionalization reaction is accompanied by ester exchange reaction with the solvent. In this method, α-bromocarboxylates are used as radical precursors and 2-amino-1,4-naphthoquinones as radical trapping reagents. The substrate scope is broad because various aromatic alkenes, 2-amino-1,4-naphthoquinones, and α-bromocarboxylates are employed in the reaction, and corresponding products are obtained in moderate to good yields.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2015
·
IF 4.152
Tao Feng,Bin Pi,Bin Li,Lei Jiang,Yi-Meng Wang,Xue-Song Zhu,Hui-Lin Yang
Calcium phosphate cements (CPCs) are popular bone filling materials and drug carriers. However poor mechanical properties and lack of osteoinduction restrict their clinical applications. Recent studies suggested the osteogenic properties of NAC. In our study, we incorporated NAC with α-TCP/SF. We found that the compressive strength of α-TCP/SF-NAC composites increased with increase in NAC concentration, possibly due to complex three-dimensional networks of SF induced by NAC, which was large and chemically heterogeneous and induced compact oriented growth of HA crystals. However the setting time increased slightly with the addition of NAC, due to the ruptured disulfide bonds in SF. The α-TCP/SF-NAC composites also showed decent biocompatibility in vitro. As a result, these composites hold great potential as bone filling materials for clinical applications, including minimally invasive surgeries.
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