CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhichao Sun,Songyin Yu,Yuhang Gong,Changhai Liang,Chuang Li
Different from the dehydration of ethanol, the catalytic dehydration of long-chain fatty alcohols to linear α-olefins with the low selectivity arises from a complex reaction network, particularly the secondary isomerization to internal olefins. This study aimed to elucidate the fundamental mechanisms governing selectivity in the catalytic dehydration of n-octanol to 1-octene over conventional γ-Al 2 O 3 catalysts. The combination of kinetic analysis, in situ infrared spectroscopy, and density functional theory (DFT) calculations, we demonstrated that the reaction primarily proceeded via a dioctyl ether intermediate, which rapidly decomposed into olefin and alcohol. In contrast, the isomerization of 1-octene followed a water-assisted re-adsorption and hydration pathway: 1-octene re-adsorbed onto surface acid sites, hydrated to form 2-octanol, and subsequently underwent secondary dehydration, preferentially yielding internal olefins in accordance with Saytzeff's rule. Based on these mechanistic insights, an integrated reaction-separation process was designed using Aspen Plus simulation. Employing a dual-column distillation scheme with heat integration, the process achieved a 1-octene product purity exceeding 98% with ~5.9% lower overall energy consumption. This work provided systematic insights and a feasible strategy, that bridges molecular-scale mechanisms with process engineering, facilitating the highly selective production of α-olefins from biomass-derived long-chain alcohols.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2026
·
IF 2.4
Long He,Lei Qin,Liang Chen,Lifang Chen,Zhiwen Qi
The removal of γ-butyrolactone (GBL) from N-methyl-2-pyrrolidone (NMP) to produce electronic-grade NMP is a significant challenge to meet the rigorous purity standards of semiconductor manufacturing. Therefore, reliable thermodynamic data and models are essential for designing an intensified separation process. Herein, isobaric vapor–liquid equilibrium (VLE) data for the {NMP + GBL} binary system at 10.0, 20.0, and 101.3 kPa were determined by a Fischer Labodest VLE 602 ebulliometer. The results show that the {NMP + GBL} system is a close-boiling nonazeotropic mixture over the investigated pressure ranges. To verify the reliability of the experimental data, Herington area and Van Ness point tests used to determine the thermodynamic consistency of VLE data illustrate that all of the data have passed the test. In addition, the VLE data measured in the experiment are correlated with nonrandom two-liquid (NRTL), Wilson, and UNIQUAC activity coefficient models, and all three models show good agreement with the experimental data for this binary system. This study provides essential thermodynamic data and model parameters to support the development of purification processes for electronic-grade NMP.
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JOURNAL OF MATERIALS SCIENCE
·
2025
·
IF 3.9
Wu Yue,Yuchao Qi,Xue Ying,Hao Xiaonan,Sun Shulin,Zhao Jingxuan
The escalating industrial activities in metal processing, textile manufacturing, petroleum refining, leather production, and pulp industries have generated substantial amounts of industrial wastewater, presenting critical environmental challenges that require immediate attention. In this study, we developed a novel polyacrylonitrile grafted ionic liquid (PAN-g-IL) membrane through γ-ray irradiation-induced grafting of 1-vinyl-3-ethylimidazolium bromide onto polyacrylonitrile, followed by non-solvent induced phase separation (NIPS) membrane fabrication [1] . The developed membrane exhibited exceptional separation performance for both dye-laden and oil-contaminated wastewater systems. The PAN-g-IL membrane demonstrated a pure water flux of 358.1 L m −2 h −1 with remarkable rejection rates exceeding 98% for cationic dyes, and for oil–water emulsions has a very good retention performance [2] , indicating superior antifouling properties and long-term operational stability.
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POLYMER COMPOSITES
·
2026
·
IF 4.7
Mengfei Du,Enhao Zhu,Xilai Yan,Zhe Wang,Ke Wang
Enhancing the durability of ultraviolet-cured-in-place pipe (UV-CIPP) in alkaline environments remains challenging due to its long-term exposure to concrete pore solution from the original pipe. Herein, a novel strategy that γ-AlOOH coating assists to immobilize Irganox 1010 onto glass fibric (GF) was proposed for simultaneously improving alkaline corrosion resistance and mechanical properties of UV-CIPP. Through the beneficial bridging of γ-AlOOH with the coupling agent, Irganox 1010 was immobilized on the GF (GF-Al-g-1010) surface through hydrogen bonding and covalent bonding. The leaching of Si 2+ from the GF backbone of unsaturated polyester resin (UP)/GF-Al-g-1010 composite was reduced by 40.60% and the hydrolyzed alcohol products decreased by 47.1%. Meanwhile, the mechanical properties of UP/GF-Al-g-1010 remained well preserved. The flexural and tensile modulus retained at 99.0% and 96.3%, respectively. The immobilization of Irganox 1010 at the UP/GF interface formed a protective hydrophobic layer and stabilized free radicals, which together inhibited resin degradation and reduced interface debonding. Moreover, the flexural strength and modulus of composites increased by 36.5% and 38.4%, respectively. The chemical bonding between GF-Al-g-1010 and UP chains enhanced interfacial adhesion. In summary, this work will facilitate the design of UV/thermal dual-cured composites with high strength and alkaline corrosion resistance for pipeline rehabilitation. Highlights A novel AlOOH coating assists to immobilize Irganox 1010 onto glass fabric. The flexural strength and modulus increased 36.5% and 38.4%, respectively. The Si 2+ leaching and hydrolyzed alcohol products were reduced by 40.60% and 47.1%. The flexural and tensile modulus retention reached 99.0% and 96.3%, respectively. The AlOOH-1010 coating improved both durability and mechanical properties.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2022
·
IF 9.463
Linlin Wang,Fenghua Zhang,Shanyi Du,Jinsong Leng
The cross-linking degree is a significant factor affecting the thermodynamic properties of resins, the cross-linking degree of photosensitive resins is limited during Digital Light Procession (DLP) printing. We present a strategy for double networks in epoxy resin to further improve the performances of printed structures via two different processing methods. Epoxy acrylates and polyethylene glycol dimethacrylates crosslink by UV-light radiation forming a light-induced network structure, and epoxy molecules crosslink under γ-ray radiation forming a ray-induced network structure. The two kinds of networks interpenetrate to form the interpenetrating polymer network (IPN). The printed IPN specimens have the characteristics of high Young’s modulus (up to 4.89 GPa) and fracture strain (as high as 30.4 %). The printed flowers and canister reinforced by short glass fibers (GFs) exhibited rapid shape recovery behaviors. The IPN epoxy/GFs composites have good values in manufacturing smart deployable structures , medical devices , and automobile shell parts.
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BIOMACROMOLECULES
·
2012
·
IF 5.479
Longlong Chang,Liandong Deng,Weiwei Wang,Zesheng Lv,Fuqiang Hu,Anjie Dong,Jianhua Zhang
A novel biodegradable amphiphilic diblock copolymer methoxy poly(ethylene glycol)-b-poly(ε-caprolactone-co-γ-hydroxyl-ε-caprolactone) (mPEG-b-P(CL-co-HCL)) bearing pendant hydroxyl groups on the PCL block was prepared. The hydroxyl groups were formed through the reduction of ketones by sodium borohydride without protection and deprotection. The obtained polymers were well characterized by 1H NMR, Fourier transform infrared (FT-IR), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), X-ray diffraction (XRD), and contact angle measurement. mPEG-b-P(CL-co-HCL) could self-assemble into stable nanoparticles (NPs) with critical micellar concentrations (CMC) of 6.3 × 10–4 ∼ 8.1 × 10–4 mg/mL. The NPs prepared from mPEG-b-P(CL-co-HCL) were spherical in shape with diameters about 100 to 140 nm. The hydrophobic doxorubicin (DOX) was chosen as a drug model and successfully encapsulated into the NPs. The encapsulation efficiency and release kinetics of DOX were investigated. The results indicated that the introduction of hydroxyl groups onto the core-forming block could decrease the hydrophobicity of copolymers, thus improving the storage stability of NPs in aqueous solution. Moreover, higher loading capacity and slower in vitro release of DOX were observed, which was due to the hydrogen-bonding formation between DOX and hydroxyl groups. Meanwhile, the MTT assay demonstrated that the blank NPs were biocompatible to HepG2 cell,s while free DOX and DOX-loaded NPs showed significant cytotoxicity against the cells. Moreover, Compared to the free DOX, the DOX-loaded NPs were more efficiently internalized by HepG2 cells. In sum, the introduction of hydroxyl groups on the polyester block in mPEG-b-P(CL-co-HCL) exhibited great potentials for modifications in the stability, drug solubilization, and release properties of NPs.
研究领域:
高分子科学
·
药物递送
·
纳米医学
·
生物材料
·
制药技术
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CARBON
·
2026
·
IF 11.6
Wenjun Zhang,Youhai Huang,Sifan Zhang,Sanqiang Zhang,Zhaohua Fang,Meng Chen
As a rising new member of carbon allotropes, graphdiyne has shown great potential in various fields due to its fascinating properties. Herein, a controlled two-step hydrothermal route was employed to convert hydrogen-substituted γ-graphdiyne into two functional derivatives: graphdiyne oxides (OGDY) and graphdiyne oxide quantum dots (OGDYQD). Systematic characterization revealed distinct differences in morphology, chemical structure, and optical properties between precursors and derivatives. Especially, the existence of alkyne bonds was demonstrated through evidence from Fourier transform infrared spectroscopy (FTIR), photoluminescence spectroscopy (PL), and selective oxidation experiments, which provides new insights for the characterization of graphdiyne materials. Moreover, we identified an oxidation-locking phenomenon governing selective alkyne oxidation at specific sites during synthesis. The oxidation-locking feature endowed significant application potential upon both derivatives: OGDY exhibited excellent photocatalytic ability in the degradation of cationic dyes, achieving efficiency ∼5–200 higher than those of other carbon-based materials; while OGDYQD could achieve ultrasensitive electrochemical detection of methyl orange with a limit of detection (LOD) as low as 0.032 μM, as well as serve as an excellent catalyst, which was comparable to metal catalysts, for the hydrogenation of 4-nitrophenol. This work provides fundamental insights into sp-carbon reactivity while delivering practical platforms for multiple applications.
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Materials Today Bio
·
2026
·
IF 11
Caifeng Guo,Xin Shen,Rui Wang,Zhijie Bai,Lin Lin,Jiading Weng,Ningning Wang,Pan Shen,Lei Zhou,Shaoyun Guo,Xianlong Zhang,Wei Zhou,Yue Gao
With the widespread application of nuclear energy, the associated risks of nuclear accidents and radiation leakage have increased considerably. To address potential acute radiation injuries and reduce the toxicity burden posed by conventional radioprotective agents, the development of novel therapeutic strategies is urgently needed. In this study, we designed a γ-radiation-responsive drug delivery system by encapsulating the radioprotective agent cannabidiol (CBD) into amphiphilic polymer micelles (denoted as mPEG-SeSe-St@CBD) incorporating diselenide bonds as radiation-sensitive units. The resulting micelles exhibited a small particle size (≈155 nm), negative surface charge (zeta potential = −14.5 mV), and a stable spherical morphology. In vitro drug release studies demonstrated that the CBD-loaded micelles responded sensitively to low-dose γ-irradiation, achieving over 60% cumulative release within 6 h, with release kinetics governed by Fick diffusion. In vivo evaluations revealed that the polymeric micelles not only promoted body weight recovery in irradiated mice, but also facilitated cellular and tissue uptake, alleviated intracellular oxidative stress, and conferred multi-organ protection. As a result, the 30-day post-irradiation survival rate was enhanced to over 50%. In the absence of radiation, the micelles can remain intact spherical structure, thereby reducing the risk of drug exposure. Collectively, this study presents a radiation-sensitive nanoplatform with radioprotective efficacy, offering a promising new approach for the prevention and treatment of acute radiation injuries.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
·
IF 4.2
Zhiyuan Yu,Chengyu Guo,Xinmei Pang,Yuge Shen,Mingtang Gao,Shenyuan Zhao,Yujun Wang,Guangsheng Luo
A coprecipitation method was developed for the synthesis of fibrous γ-alumina using serial membrane dispersion microreactors with a circulating continuous phase and high concentrations of NaAlO2 and Al2(SO4)3 as reactants. Owing to the ultra-high mixing intensity and reduction of supersaturation due to the large circular phase ratio, a large pore volume and specific surface area and an extremely narrow pore diameter distribution were realized using the high-concentration and high-viscosity precipitation system. The influence of the phase ratio, dispersion order of reactants, Al2(SO4)3 residence time, and the precipitation reaction pH and time were investigated, and the nanofiber formation mechanism was explored employing theoretical calculations. By controlling the Al2(SO4)3 residence time of 3 s, phase ratio of 16, and pH of 8.0, γ-Al2O3 nanofibers with a pore volume of 1.36 cm3/g, a specific surface area of 376 m2/g, and a length/diameter ratio in the range of 30–54 were obtained without any organic reagents. This study provides an economical and readily scalable method for the synthesis of fibrous γ-Al2O3 with excellent pore properties and a large specific surface area, which can potentially be applied as an excellent catalyst support for diesel and bio-oil hydrogenation.
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Journal of Materials Chemistry B
·
2022
·Vol. 11
·期 3
·667-674
·
IF 7.571
Zheng Zhang,Weichen Yan,Yuanhui Ji
Cisplatin (CDDP) is one of the most frequently used chemotherapeutic drugs due to its broad-spectrum and potent antitumor activity. Unfortunately, inactivation due to glutathione (GSH) substances and insufficient cellular uptake of CDDP greatly hinder its clinical applications. Herein, manganese dioxide (MnO2) was reported as an efficient glutathione (GSH) consumption material for promoting the accumulation and preventing premature leakage of CDDP in tumor cells. In this work, γ-polyglutamic acid/cisplatin (PGA/CDDP) conjugates and PGA/CDDP nanoparticles (NPs) were respectively constructed via the ligand exchange reaction and electrostatic interaction. Furthermore, PGA/CDDP NPs were in situ coated with MnO2 (PGA/CDDP@MnO2 NPs) through the redox reaction of the residual carboxyl group (–COOH) and potassium permanganate (KMnO4). As a result, the PGA/CDDP@MnO2 NPs achieved a satisfactory drug-loading efficiency (ca. 37.26%) and multi-responsive controlled drug release. Remarkably, the MnO2 shells exhibited excellent performance for efficient glutathione (GSH) consumption and significantly enhanced the killing effect (ca. 2–3 times) in human lung cancer cells (A549) compared with pure CDDP. Moreover, it was observed that PGA/CDDP@MnO2 NPs could also inhibit the migration and invasion of A549 cells. Overall, these remarkable performances of PGA/CDDP@MnO2 NPs make MnO2 promising for controlled drug release and intelligent anticancer therapy.
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FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Ling Zheng,Jinfeng Zhong,Xiong Liu,Qiang Wang,Xiaoli Qin
With an aim to prepare a novel formula for healthy oleogel, diacylglycerol (DAG)-rich oil as a continuous oil phase, ethyl cellulose (EC) as a gelator and γ-oryzanol (GO) as an antioxidant were used. Effects of EC viscosity and EC/GO mass ratio on the physicochemical properties were studied. Besides, interactions between the components were analyzed by Fourier transform infrared spectroscopy and molecular dynamics (MD) simulation. The EC with a viscosity of 18–22 mPa s resulted in slightly higher oil binding capacity (99.84% vs 98.55% at 10% EC, and 99.92% vs 99.49% at 12% EC) and significantly stronger hardness and gel strength of DAG oil oleogels than EC with a viscosity of 45–55 mPa s. Moreover, the hardness and rheological properties of oleogels were negatively correlated to GO addition. MD simulation was used to understand this effect of GO addition, showing that EC-GO complex had lower binding energy (−107.14 kJ/mol) than the complexes of GO-DAG (−105.64 kJ/mol) and EC-DAG (−101.96 kJ/mol), leading to the disruption of the capacity of EC to structure DAG-rich oil. Interactions between the components were mainly governed by van der Waals interactions. The peroxide value of the oleogels decreased by 1.89 mmol/kg as EC18/GO mass ratio changed from 12:0 to 12:4, indicating good antioxidant activity of GO. Overall, the characteristics of DAG oil oleogels could be modulated by the addition of GO. The study may provide considerable potential to develop healthy and stable oleogels with high DAG, low saturated and trans -fatty acids for food industry.
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JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Zongping Jia,Chengying Du,Lulu Zhu,Zhonglai Wang
An alumina porous layer open-tubular (Al 2 O 3 PLOT) column coated with γ–alumina nanoparticles (20 nm) for highly volatile hydrocarbons (C1 to C5) separation was described. Relative to the coating of bulk alumina, this column was easily coated with dynamic method under 0.4 or 0.6 MPa for 0.53 mm or 0.32 mm capillary, respectively. And the thickness of coating layer could be tuned by repeating the coating process after column was dried and activated at 300 °C for 3 h. The effect of deactivation agents on the physicochemical properties of nano γ–alumina was characterized by X–ray diffraction (XRD) measurement and nitrogen adsorption–desorption isotherms. The influences of deactivation agents, film thickness, conditioning and column dimensions on the inertness, polarity, selectivity and elution order of C1 to C5 separation were investigated in detail. The crystallite structure and size of nano alumina were not affected by the deactivation agents and remained constant during the column making processes, whereas specific surface area, pore volume and average half pore width altered significantly. The specific surface area decreased to 125.4 m 2 g –1 or 174.0 m 2 g –1 and the average half pore size distributions decreased to 1.6–8.4 nm or 2.4–14.3 nm when it was deactivated with potassium chloride or sodium sulfate solution, respectively. The deactivation agents and its concentrations impacted significantly on the retention performance of column. The column deactivated with sodium sulfate solution exhibited stronger polarity and lower selectivity than which deactivated with potassium chloride solution although both columns showed good inertness. The length, internal diameter and film thickness of the column had less influence on the selectivity and resolution for C1 to C5 hydrocarbons separation, whereas the conditioning temperature and time had an obvious influence. The column had distinguished polarity and selectivity which was different from either bulk or commercial alumina columns. Typically, the hydrocarbons were baseline separated with resolutions ranging from 1.65 to 15.33 within 9 min under programmed temperature below 100 °C, and the tailing factors ranging from 1.02 to 1.07.
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