Frontiers in Chemistry
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2018
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IF 4.155
Jiang Zi-Min,Xu Ting-Ting,Yan Cong-Cong,Ma Cai-Yun,Dai Shu-Ge
Here, we report our finding in the fabrication of novel porous urchin-like Ni2/3Co1/3(CO3)1/2(OH)·0. 11H2O (denoted as NC) nanomaterial composed of numerous nanoneedles through an one-step hydrothermal method, which deliveres a high specific capacity of 318 C g−1 at a current density of 1 A g−1. Moreover, an architectural composite electrode consisting of the porous NC nanoneedles wrapped by reduced graphene oxide (rGO) nanosheets exhibits large specific capacity (431 C g−1 at 1 A g−1), high rate capability and long cycling life (94% capacity retention after 5,000 cycles at 20 A g−1). The presence of rGO in the composite electrode greatly improves the electronic conductivity, providing efficient current collection for fast energy storage.
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ACS Sustainable Chemistry & Engineering
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2021
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IF 8.198
Liqing Li,Luo Feng,Yu Xiao,Wenqi Xie,Xiaoqi Sun
In this work, a new type of near-infrared (NIR) reflective yellow pigment with a general formula of [(Li0.4RE0.6Al0.6)x/2Bi1–x][MoxV1–x]O4 was prepared by a solid-phase reaction calcined at a high temperature of 700 °C. X-ray diffraction (XRD), scanning electron microscope (SEM), a UV–vis–NIR spectrophotometer, and other methods were used to characterize the structure, morphology, and optical properties of synthetic pigments. For a series of [(Li0.4RE0.6Al0.6)x/2Bi1–x][MoxV1–x]O4 pigments, when x > 0.2, bismuth vanadate changes from the monoclinic phase (space group I2/b(15)) to the tetragonal scheelite phase (space group I41/a(88)). The structures of the pigments are all tetragonal scheelite phases, and the difference in their color rendering is mainly due to the differences between the valence band and the conduction band and the difference in the band gap caused by different rare earth elements. The NIR reflectance (R %) and NIR solar reflectance (R* %) of [(Li0.4La0.6Al0.6)0.1Bi0.8][Mo0.2V0.8]O4 pigments are 96.64 and 93.10% (b* = 77.13, C* = 77.6), respectively. In the acid and alkali resistance test, the color difference values ΔE* of the pigment before and after soaking are less than 5. Finally, the thermal infrared test of the synthetic pigments and commercial pigments on galvanized plates without or with TiO2 was performed. The experimental results show that the temperature difference between the synthetic pigment and commercial bismuth yellow can reach 11 °C. Therefore, it is believed that the synthetic pigment can reflect more heat radiation from sunlight and has better heat insulation performance. The synthetic pigment has higher reflectivity than the commercially available bismuth vanadate pigment, showing its application potential.
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INTERNATIONAL IMMUNOPHARMACOLOGY
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2025
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IF 4.7
Yuanyuan Wang,Ruibo Guo,Baoli Xu,Ming Zou,Liang Kong,Chuan Tang,Runchao Jiang,Wei Wang,Xuan Zhang,Guangyao Lv
Introduction: Rheumatoid arthritis (RA) is an autoimmune disease characterized by persistent synovitis and the formation of pannus, leading to proliferation of synovial tissue and destruction of bone and cartilage. Traditional drug therapy is often limited by the lack of drug targeting and the continuous synovial angiogenesis. Herein, a dual-targeted micelles for macrophages and vascular endothelial cells with excellent anti-inflammatory and anti-angiogenic properties was constructed to effectively treat RA. Methods: We developed vascular cell adhesion molecule-1 (VCAM-1) binding peptide modified polyphyllin I (PPI) loaded micelles (VM-PE@Ms) in which eucommia ulmoides polysaccharide (EUP) was used as the hydrophilic parts of the hybrid micelles. The targeting, ROS scavenging effect, anti-inflammatory activity, and inhibition of angiogenesis of the micelles were assessed in vitro. Collagen-induced arthritis (CIA) rats model was employed to explore targeting, impact on inflammatory cytokine levels, and cartilage protective effect of the micelles in vivo. Results: VM-PE@Ms. exhibited targeting to both activated RAW264.7 cells and human umbilical vein endothelial cells (HUVECs), and strong inhibitory effect of inflammatory cytokine secretion, ROS generation, and angiogenesis. In vivo assays demonstrated that VM-PE@Ms. displayed desirable pharmacodynamics property, which was confirmed by precise inflammatory joint targeting and retention capacity and bone erosion remission effects and was related to suppression of inflammation and synovial angiogenesis. Conclusion: In summary, the proposed dual-targeted hybrid micelles have the potential role for anti-inflammatory and anti-angiogenic therapy of RA.
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JOURNAL OF POWER SOURCES
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2020
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IF 8.247
Ze Wang,Jiantuo Gan,Xiaodong Liu,Hangbo Shi,Qi Wei,Qiugui Zeng,Liang Qiao,Yonghao Zheng
All-inorganic cesium lead halide perovskites (CsPbX 3 , X = Cl, I, Br) have attracted great attention for developing high-performance photovoltaics due to their superb thermal stability. However, the short electron-hole diffusion lengths ( L D s) in CsPbI 2 Br perovskite are the primary limiting factor for further improvement of the power conversion efficiencies (PCEs) of the CsPbI 2 Br solar cells. Herein, a simple yet effective method is reported to prolong the L D s in CsPbI 2 Br via codoping of Zn 2+ and acetate (Ac − ) ions (i.e., using Zn(Ac) 2 as dopant). It is demonstrated that Zn 2+ partially replaces Pb 2+ to form a more stable black phase, and Ac − coordinates with Pb 2+ to passivate the defects at the perovskite grain boundaries which reduces electron-hole recombination within the perovskite. As a result, the L D s of Zn(Ac) 2 doped CsPbI 2 Br are greater than 1 μm, which is the first report on all-inorganic perovskites. The champion PCE of the CsPbI 2 Br solar cells is drastically increased from 12.31% to 14.93% upon doping with Zn(Ac) 2 , stemming mainly from the increased open-circuit voltage and fill factor. Furthermore, the non-encapsulated devices with Zn(Ac) 2 doped CsPbI 2 Br show less than 10% efficiency loss after storage in dry air for 30 days.
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iScience
·
2021
·
IF 5.458
Dejun Zeng,Liyong Yuan,Pengcheng Zhang,Lin Wang,Zijie Li,Youqun Wang,Yunhai Liu,Weiqun Shi
HKUST-1@CMC (HK@CMC) composites that show good acid and alkali resistance and radiation resistance were successfully synthesized by introducing carboxymethyl cellulose (CMC) onto the surface of HKUST-1 using a foaming strategy. For the first time, the composites were explored as efficient adsorbents for U(VI) trapping from aqueous solution, with encouraging results of large adsorption capacity, fast adsorption kinetics, and desirable selectivity toward U(VI) over a series of competing ions. More importantly, a hybrid derivative film was successfully prepared for the dynamic adsorption of U(VI). The results show that ∼90% U(VI) can be removed when 45 mg L −1 U(VI) was passed through the film one time, and the removal percentage is still more than 80% even after four adsorption-desorption cycles, ranking one of the most practical U(VI) scavengers. This work offers new clues for application of the Metal-organic-framework-based materials in the separation of radionuclides from wastewater.
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JOURNAL OF HAZARDOUS MATERIALS
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2024
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IF 12.2
Mingliang Zhang,Weihao Zhu,Hongfei Liu,Kaihua Pan,Qian Li,Qian Zhu,Yanni Huang,Changchang Wang,Junqiang Hu,Mingli Jiang,Xin Yan,Qing Hong
Acetaminophen (APAP), an analgesic and antipyretic drug, is commonly detected in wastewater treatment plant (WWTP) effluents, surface water, and soil, indicating its status as an emerging environmental contaminant. In this study, we isolated a bacterium, Pseudomonas taiwanensis AP-1, capable of completely mineralizing APAP and utilizing it as the sole carbon source for growth. A newly identified metabolite, γ-glutamyl-4-aminophenol (γ-G4AP), was reported for the first time in the degradation of APAP by strain AP-1. Two amidases (ApaH1 and ApaH2), responsible for the conversion of APAP to 4-aminophenol (4-AP), were identified through a combination of genomic comparison, heterologous expression, and gene knockout. Notably, ApaH1 played a pivotal role in the degradation of APAP by strain AP-1. The catalytic triad of ApaH1 (K82-S161-S185) and ApaH2 (K85-S160-S184) were identified as by molecular docking and site-directed mutagenesis. Additionally, a gene cluster apd for the metabolism of 4-AP was also successfully identified in strain AP-1, consisting of the aniline dioxygenase gene cluster apdBCD1D2EF and the BT catabolic gene apdGH . Interestingly, the 4-AP metabolic gene cluster apd was highly conserved among other Pseudomonas strains capable of APAP degradation. Our results provide new insights into the mechanism of APAP biodegradation and strain AP-1 may be a promising bacterium for the bioremediation of APAP pollutions.
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JOURNAL OF ELECTRONIC MATERIALS
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2024
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IF 2.2
Cao Yang,Zhang Yong,Wei Wei,Wang Chen,Zhao Xiaoyu,Chen Xudan,Lu Zhenhao
Organic–inorganic metal halides have recently garnered significant interest owing to their excellent photoluminescence performance and high stability. Therefore, a synthetic procedure was designed here to obtain (PPZ)ZnBr 4 (PPZ = 1-phenylpiperazine) nanocrystals (NCs) incorporating Pb 2+ and Sn 2+ ions, obtaining blue and orange light emitters, respectively. Photoluminescence quantum yields of blue and orange emissions were up to 43.2% and 29.9%, respectively, under 365-nm excitation. The prepared NCs also demonstrated long-term stability and humidity resistance. This study not only provided a deep comprehension of low-dimensional perovskites, but also established an avenue for the strategic design of high-performance light-emitting perovskites.
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INORGANIC CHEMISTRY COMMUNICATIONS
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2024
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IF 4.4
Yujuan Sun,Jun Wu,Xiashi Zhu
A novel poly[1-vinyl-3-benzyltriethylammonium proline ionic liquid] membrane(PIL/PVDF membrane) were prepared through the blending poly[1-vinyl-3-benzyltriethylammonium proline ionic liquid](P[Pro][TEA])-poly(vinylidene fluoride)(PVDF) phase inversion method. A series of PIL/PVDF membrane characterization (NMR, FT-IR, SEM, EDS, and XPS) was performed. The properties of PIL/PVDF membrane (contact angle, water flux, mechanical properties, thermal stability,electric charge property, specific surface area and pore diameter) were evaluated. A solid phase extraction − high performance liquid chromatography (SPE-HPLC) method for separation/analysis of quercetin was developed. The factors affecting the adsorption and elution (time, dosage, pH etc.) were investigated. Under optimal conditions, the method has been successfully applied to the separation/analysis of quercetin in tea, and the recovery rates are satisfactory (86.4–106.0 %). The concentration factor of quercetin was 10. The adsorption capacity of PIL/PVDF membrane towards quercetin was 22.1 mg g −1 . The extraction mechanism was preliminarily discussed. The established SPE-HPLC method was simple and reliable, which provided application prospects for extraction and detection of quercetin.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2025
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IF 6.2
Jing Huang,Siyi Chen,Weipeng He,Yinan Xiao,Nana Wang,Lili Huang
Phenazine-1-carboxylic acid (PCA), as a broad-spectrum antifungal agent, showed significant resistance against the Apple Valsa canker caused by Valsa mali (V. mali). Therefore, it is of great importance to reveal the functions and mechanisms of PCA in plant pathogens, which would provide potential targets for crop disease control. In this study, we identified the major contribution of PCA in the resistance of Pseudomonas chlororaphis subsp. aureofaciens W9-1 to V. mali by gene knockout and high-performance liquid chromatography. Subsequently, we demonstrated that PCA could target isocitrate lyase (ICL) to exert a broad-spectrum antifungal effect by molecular docking, microscale thermophoresis, and isothermal titration calorimetry. Furthermore, lipidomics analysis shows that PCA alters the lipid balance at the cell membrane of V. mali. In summary, this study demonstrates that PCA has a broad-spectrum antifungal effect by targeting the ICL, which may be a potential target for the development and utilization of fungicides.
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International Journal of Nanomedicine
·
2025
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IF 6.5
Ren Na,Jianmei Jing,Hua Yang,Ye Li,Xiaofeng Yuan,Xue Sun,Jiangfan Han,Jiajun Wang,Zhenhua Tong,Guangbin He,Weiliang Ye
Objective Methotrexate (MTX) is widely used for rheumatoid arthritis (RA) but has poor targeting and significant side effects. This study developed MTX-loaded lipid nanoparticles modified with PVCAM-1 peptide (MTX@LNP-PVCAM-1) to enhance targeting and reduce toxicity.Methods MTX@LNP-PVCAM-1 was prepared using the thin-film dispersion method. Particle size and morphology were assessed by dynamic light scattering (DLS) and transmission electron microscopy (TEM). Biocompatibility was tested using human umbilical vein endothelial cells (HUVEC) and hemolysis assays. Cellular uptake was examined via fluorescence microscopy, while cytotoxicity and cell migration inhibition were evaluated using CCK-8 and scratch assays. Inflammatory cytokines (IL-1β, IL-6) were measured by ELISA. Distribution in adjuvant-induced arthritis (AIA) rats was observed using in vivo imaging, and safety and anti-inflammatory effects were assessed through blood tests, paw volume, joint scores, and histology.Results MTX@LNP-PVCAM-1 had an average particle size of 168.5 nm, PDI of 0.142, and zeta potential of −12.1 mV, with spherical morphology. It exhibited pH responsiveness and good biocompatibility. Compared with unmodified MTX@LNP, PVCAM-1 surface modification significantly increased cellular uptake efficiency (p<0.05) and more effectively inhibited the growth (p<0.05), migration (p<0.05), and secretion of inflammatory cytokines (significantly reduced levels of IL-1β and IL-6, p<0.05) of synovial fibroblasts. In animal experiments, the accumulation of MTX@LNP-PVCAM-1 in inflamed sites was significantly higher than that of MTX@LNP (p<0.05), demonstrating good targeting. Moreover, it enhanced the anti-inflammatory effects of methotrexate in AIA rats, significantly reducing paw swelling (p<0.05) and joint clinical scores (p<0.05). Importantly, it had no significant effect on the blood routine indicators of rats (p>0.05), indicating no obvious toxicity.Conclusion MTX@LNP-PVCAM-1 combines passive and active targeting, delivering MTX efficiently to inflamed sites and reducing toxicity. This approach enhances anti-inflammatory effects in AIA rats, offering a potential strategy for low-toxicity RA treatment.
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Joule
·
2024
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IF 38.6
Qiaonan Zhu,Dandan Yu,Jiangchun Chen,Liwei Cheng,Mengyao Tang,Yingyu Wang,Yuting Li,Jie Yang,Hua Wang
High-energy cryogenic batteries have been pursued throughout the past decades. Anode-free batteries offer a promising avenue to boost energy density because they comprise weightless anodes. However, their low-temperature operation is challenged by poor metal plating/stripping reversibility and unstable solid electrolyte interphase (SEI). Herein, the first low-temperature anode-free sodium battery is fabricated by simultaneous surface modification of the current collector and electrolyte design. The plasma-treated current collector (p-Al@C) possesses a sodiophilic N-doped carbon surface, enabling uniform sodium nucleation and growth; meanwhile, the optimized weak-solvation electrolyte facilitates Na + desolvation and the formation of a B/F inorganic-contained SEI. Na||p-Al@C half cells exhibit an ultrahigh average Coulombic efficiency of 99.88%, and p-Al@C||Na 3 V 2 (PO 4 ) 3 batteries achieve an energy density of 250 Wh kg −1 cathode + anode at −40°C. More interestingly, Ah-level anode-free pouch cells deliver a remarkable energy density of 110 Wh kg −1 entire cell at −40°C. This work represents a critical step for low-temperature sodium batteries.
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RSC Advances
·
2015
·Vol. 6
·期 4
·3393-3398
·
IF 3.84
Yusheng Yuan,Xin Huang,Shaopu Liu,Jidong Yang,Ruilin Duan,Xiaoli Hu
In neutral conditions, hypochlorite-assisted oxidative conversion of 1-pyrenylboronic acid into 1-hydroxypyrene, which leads to 1-pyrenylboronic acid fluorescence quenching, was used as the signaling tool. Compared with 1-pyrenylboronic acid, the maximum excitation (λex = 347 nm) and emission (λem = 392 nm) wavelength of 1-hydroxypyrene had no obvious change. The surfactant Triton X-100, as a micellar additive, was not only used to enhance the stability of the fluorescence probe, but also to improve its sensitivity. When using Triton X-100, the signaling of 1-pyrenylboronic acid was markedly enhanced. Herein, a spectrofluorimetric method for highly selective and sensitive hypochlorite determination has been performed. It can be noted that the fluorescence intensities positively correlated with the hypochlorite concentration over the range of 0.69–6.0 μmol L−1. The detection limit was 0.21 μmol L−1, which is lower than for most of the recently published methods. The experimental conditions were optimized and the effects of coexisting substances are evaluated. The results showed excellent priority because a certain amount of ions, including SO32−, NH4+, Cu2+ and other acid radicals, would not interfere with the measurement. The accuracy and reliability of the method was further ensured by recovery studies using the standard-addition method. In addition, the quenching mechanism, which was proven to be static quenching, has been investigated systematically by the linear plots at varying temperatures based on the Stern–Volmer equation, fluorescence lifetime, and UV-visible absorbance spectra. This method was finally used to detect hypochlorite in local water samples.
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