OPTICAL MATERIALS
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2022
·
IF 3.754
Yuanjie Wang,Tengfei Cao,Zhihuang Xu,Liwang Ye,Xinxin Zhuang
Organic-inorganic hybrid halides (OIHs) have attracted widespread attention because of their exceptional optoelectronic properties. In particular, Mn 2+ -based hybrid halides show intense green or red emission, which benefit from distinct d-d optical transition in Mn 2+ . This work deals with the dual-emission in two novel hybrid single-crystals (N-AEP)[MnCl 3 (H 2 O) 3 ] 2 ·Cl ( 1 ) and [(N-AEP) 2 MnCl 6 ]·2Cl ( 2 ) (N-AEP 3+ = C 6 H 18 N 3 3+ ). Luminescence properties studies indicate that the low-energy emission is assigned to the Mn 2+ -based octahedron , while the high-energy emission ascribes to the organic cation [N-AEP] 3+ . Inorganic polyhedron transformation ([MnCl 3 (H 2 O) 3 ] - to [MnCl 6 ] 4- ) increased the luminescent intensity, which benefited from the weaker nonradiative transition in [MnCl 6 ] 4- octahedron. Significantly, by finely adjusting the excitation wavelength, complex 2 showed tunable emission properties, realizing the transition from “warm” white light (0.40, 0.33) to “cold” white light (0.28, 0.28). This paper offers a new example on the effective design of dual-emission materials.
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ACTA DIABETOLOGICA
·
2024
·
IF 3.1
Zhang Ling,Zhao Jing,Peng Zhou,Zhang Zhongxiao,Huang Shan,Dong Xiaohua,Gao Jianfang,Guo Xirong
Background Obesity, defined as excessive or abnormal body fat accumulation, which could significantly increase the risk of cardiovascular disease, type 2 diabetes mellitus (T2DM) diseases and seriously affect people’s quality of life. More than 2 billion people are overweight, and the incidence of obesity is increasing rapidly worldwide, it has become a widely concerned public health issue in the world. Diverse evidence show that active metabolites are involved in the pathophysiological processes of obesity. Aims However, whether the downstream catabolite of tryptophan, 3-indole acrylic acid (IA), is involved in obesity remains unclear. Methods We collected the samples of serum from peripheral blood of obesity and health controls, and liquid chromatography–mass spectrometry (LC-MS) was performed to identify the plasma levels of IA. Additionally, we verified the potential benefits of IA on human preadipocytes and HFD- induced zebrafish by cell viability assay, flow cytometry assay, Oil red O staining, total cholesterol (T-CHO), triglyceride (TG) and nonesterified free fatty acids (NEFA) measurements and Nile Red staining. RNA-Seq, functional analysis and western blot revealed the mechanisms underlying the function of IA. Results We found that the content of IA in peripheral blood serum of overweight people was significantly lower than that of normal people. In addition, supplementation with IA in zebrafish larvae induced by a high fat diet (HFD) dramatically reduced HFD induced lipid accumulation. IA had no effect on proliferation and apoptosis of preadipocytes, but significantly inhibited adipogenesis of preadipocytes by down-regulate CEBPα and PPARγ. RNA-Seq and functional analysis revealed that IA regulated the adipogenesis of preadipocytes through stimulate the phosphorylation of STAT1. Conclusions Taken together, IA has been identified as a potent metabolite for the prevention or treatment of obesity. Graphic Abstract
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POULTRY SCIENCE
·
2025
·
IF 4.2
Qiyue Zhang,Yue Wang,Yanwei Wang,Jielu Yuan,Yaru Wang,Yongqi Zeng,Haihua Zhang,Hui Yang,Qiugang Ma,Donghui Shi,Shimeng Huang
This study investigates the effects of 3-indoleacrylic acid (IAA), a bacterial metabolite of tryptophan, on LPS-induced liver injury in laying hens. The aim is to explore the potential hepatoprotective mechanisms of IAA, particularly through the modulation of inflammatory and antioxidant pathways. A total of 48, 24-week-old No. 6 Jingfen laying hens were randomly divided into four groups of 12 hens each: the CON group (basal diet), IAA group (basal diet + 150 mg/kg IAA), LPS group (basal diet), and IAA+LPS group (basal diet + 150 mg/kg IAA). The feeding period lasted 8 weeks, and at the end of the 8th week, the laying hens in the LPS and IAA+LPS groups were intraperitoneally injected with 0.5 mg/kg LPS. The four groups were uniformly slaughtered and sampled 12 hours after LPS injection. The expression of pro-inflammatory cytokines (IL-1β, TNF-α, IL-6) was significantly alleviated ( P < 0.05), and antioxidant enzymes (T-SOD, CAT, GSH-PX) were significantly elevated ( P < 0.05) in the serum and liver of the IAA+LPS group. Histological analysis revealed reduced hepatocyte necrosis and inflammation in the IAA-treated groups ( P < 0.05). Additionally, the activation of MAPK and Toll-like receptor (TLR) signaling pathways was modulated through transcript analyses, thereby reducing inflammation and oxidative stress. In summary, IAA effectively mitigates liver inflammation and oxidative stress through the regulation of MAPK and TLR signaling pathways, providing a promising strategy for improving liver health in hens. This study represents the first report on the application of IAA in poultry, demonstrating its potential as a novel therapeutic agent for alleviating liver injury.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2022
·
IF 5.895
Xiankun Liu,Shiqiang Wen,Weichen You,Xiaofei Wang,Qing X. Li,Qiang Bian,Pei Lv,Rimao Hua
An efficient synthesis method will allow a large number of tetramic acid analogues to be synthesized for property and potency optimization. In this study, a facile and efficient method was described for the synthesis of 3-acyltetramic acids. The synthesis was accomplished mainly via (1) mild intramolecular cyclization and (2) the formation of β-ketoamides between nucleophiles and acyl Meldrum’s acids. 3-Acyltetramic acid exhibited phytotoxicity against Echinochloa crusgalli and Portulaca oleracea. At a dosage of 750 g ha–1, 6k and 6a showed high herbicidal activity against E. crusgalli, Digitaria sanguinalis and P. oleracea, Amaranthus retroflexus, respectively. 6k inhibited the synthesis of endogenous abscisic acid, thus seedling germination and plant growth. The incorporation of various acyl Meldrum’s acids and amino acid esters was applicable to the parallel synthesis of 3-acyltetramic acids. The mode of action and herbicidal activity indicate that 3-tetramic acid had good herbicidal performance and was a promising herbicide candidate. This study will provide a reference for novel herbicide development.
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高影响因子
MOLECULES
·
2016
·Vol. 21
·期 3
·299
·
IF 2.465
Bo Jin,Rongzong Zheng,Rufang Peng,Shijin Chu
Five new bis(3-hydroxy-4-pyridinone) tetradentate chelators were synthesized in this study. The structures of these tetradentate chelators were characterized by1H-NMR,13C-NMR, FT-IR, UV-vis, and mass spectral analyses. The binding abilities of these tetradentate chelators for uranyl ion at pH 7.4 were also determined by UV spectrophotometry in aqueous media. Results showed that the efficiencies of these chelating agents are dependent on the linker length. Ligand4bis the best chelator and suitable for further studies.Keywords:chelating agent;3-hydroxy-4-pyridinone;uranium;tetradentate chelator
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LUMINESCENCE
·
2019
·Vol. 35
·期 2
·203-207
·
IF 1.691
Junfeng Qu,Han Jiang,Shuhong Xu,Chunlei Wang,Dayan Ban
The emission wavelength of organic–inorganic hybrid perovskite quantum dots (QDs) can be tuned by controlling reaction time relevant to the halide exchange. It is because halide exchange with different time would lead to different molar ratio of halides in perovskite QDs such as Cl and Br. Here, to research the ligand's effect on the halide exchange, this work synthesized 3-mercaptopropionic acid (MPA)-capped CH 3 NH 3 PbBr x Cl 3-x QDs. It was found that SH − of MPA appeared to inhibit the halide exchange during the reation. Moreover, although the MPA-capped CH 3 NH 3 PbBr x Cl 3-x QDs did not contain the chiral centre, they exhibit the optical rotation. This may provide a method for chirality manipulation of perovskite.
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Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 40
·19810-19816
·
IF 9.931
Bingcheng Yu,Huiyin Zhang,Jionghua Wu,Yusheng Li,Hongshi Li,Yiming Li,Jiangjian Shi,Huijue Wu,Dongmei Li,Yanhong Luo,Qingbo Meng
All-inorganic perovskites have aroused great interest recently because of their prominent photoelectric properties and thermal stability for stable, highly efficient perovskite solar cells. Herein, a two-step multiple spin coating method has been developed for the first time to prepare cesium halide perovskite films. In particular, dimethyl sulfoxide (DMSO) is introduced into CsBr/methanol precursor solution to increase the solubility of CsBr; in the meantime, it can also remarkably influence the morphologies, optical properties and photovoltaic performance of CsPb(IxBr1−x)3 (0 < x < 1) films. By regulating the content of DMSO, as high as 13.27% power conversion efficiency (PCE) has been achieved with a steady-state PCE of 12.5% under optimal conditions, which can maintain 98% of the initial PCE for 480 h under ambient conditions without encapsulation. The synergistic effect of the solvent-engineering method can provide a new access for good quality all-inorganic perovskite thin films for high performance optoelectronic devices.
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MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 6
·1-7
·
IF 5.479
Xiong Huayu,Wang Bei,Wen Wei,Zhang Xiuhua,Wang Shengfu
Water-soluble cadmium telluride quantum dots capped with 3-mercaptopropionic acid were synthesized and further modified with 3-aminophenylboronic acid to form boronic acid-functionalized quantum dots (QDs). Under excitation at 350 nm, the modified QDs display yellow fluorescence with a peak at 566 nm. On exposure to copper(II), the fluorescence of the QDs is quenched. Under optimal conditions, fluorescence drops linearly in the 0.01 to 20 μM Cu(II) concentration range, and the detection limit is 7.6 nM. This fluorescent probe was applied to the determination of Cu(II) in spiked human serum and water samples and gave satisfactory results.
Schematic presentation of the principle for fluorometrice detection of copper(II) based on the use of boronic acid-functionalized cadmium telluride quantum dots (CdTe QDs).
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International Journal of Applied Ceramic Technology
·
2023
·Vol. 20
·期 4
·2125-2130
·
IF 2.1
Jinghua Wu,Milad Kermani,Lei Cao,Bohan Wang,Zhiquan Dai,Le Fu,Chunfeng Hu,Salvatore Grasso
Lithium aluminum germanium phosphate solid electrolyte is a promising candidate for all-solid-state batteries. The currently available processing techniques based on melting-quenching require a rather lengthy crystallization step lasting up to 8 hours. In this work, the newly emerged ultra-fast high-temperature sintering (UHS) was proposed to achieve in a single step reactive consolidation of powder mixture (GeO 2 , Al(PO 3 ) 3 , LiPO 3 ) and crystallization of the electrolyte within 16 minutes. Samples produced using UHS had a better phase purity, reduced Li loss, and improved ionic conductivity when compared to the counterparts prepared using conventional crystallization at 850°C for 6 h. In fact, specimens prepared by UHS achieved a crystallinity of 90% and ionic conductivity as high as 1.31 × 10 −4 S cm −1 .
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Desalination and Water Treatment
·
2016
·
IF 1.272
Yong-Sheng Lu,Zhan Wang,Yun-Feng Xu,Qiang Liu,Guang-Ren Qian
Iron molybdate (Fe2(MoO4)3) was used as a novel heterogeneous catalyst to activate persulfate () for rhodamine B (RhB) degradation. Results indicated 10 mg/L RhB can be completely removed under the addition of 4 mM and 0.4 g/L Fe2(MoO4)3 within 240 min. Fe2(MoO4)3 can be repeatedly used for six cycles and showed high stability with Fe leaching amounts less than 2.9% in each run. Possible catalytic mechanism was proposed as follows: RhB degradation intermediate products such as hydroxybenzene, quinone compounds and organic compound radicals acted as electron transfer agents to reduce Fe3+ to Fe2+, which reacted with persulfate to form Fe3+ creating the redox cycling of iron, the RhB and those intermediate products are oxidized directly by the molybdenum peroxo complexes which forming probably with and persulfate, and the synergy between Fe3+ and occurring the catalytic effect on the persulfate. Additionally, the major intermediates of RhB were identified according to GC/MS and the possible degradation pathway was proposed.
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DALTON TRANSACTIONS
·
2023
·Vol. 52
·期 31
·10918-10926
·
IF 4
Yu Zhang,Xia Liu,Qian-Yan Liu,Jian-Hua Wang,Ting Hu,Yan-Mei Lin,Jian-Han Zhang
Two novel alkaline-earth zincophosphites, namely CaZn(HPO3)2 and Ba2Zn(HPO3)3, were successfully synthesized under hydrothermal conditions. CaZn(HPO3)2 exhibits a three-dimensional (3D) anionic framework with a 6-connected uni-nodal pcu α-Po primitive cubic topology, constructed by unique Zn2O8 dimers and HPO3 pseudo-tetrahedra, while Ba2Zn(HPO3)3 displays one-dimensional (1D) [Zn(HPO3)3]4− anionic chains. It is worth mentioning that CaZn(HPO3)2 represents the first example of an alkaline-earth zincophosphite compound with a 3D framework structure. Our research also revealed the importance of both alkaline earth cation sizes and Zn/P ratios in anionic open-framework formation. The crystal structures of both compounds were further verified by energy dispersive spectroscopy, IR spectroscopy and Raman spectroscopy. Optical diffuse reflectance spectra, coupled with Tauc's fitting, revealed direct bandgaps with energy values of 4.33 and 4.48 eV for CaZn(HPO3)2 and Ba2Zn(HPO3)3, respectively, which differ from the prediction of theoretical calculations. Density of states calculations were conducted to reveal the origin of the bandgaps and bond interactions. Both compounds exhibited moderate birefringence values. This work may have implications for the design and synthesis of novel metal phosphites with desired properties.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2013
·
IF 2.906
Jianxia Sun,Shun Bai,Weibin Bai,Feiyan Zou,Lei Zhang,Zhijian Su,Qihao Zhang,Shiyi Ou,Yadong Huang
3-Monochloropropane-1,2-diol (3-MCPD) is a well-known food processing contaminant that has been shown to impede the male reproductive function. However, its mechanism of action remains to be elucidated. In this study, the effects of 3-MCPD on progesterone production were investigated using R2C Leydig cells. 3-MCPD caused concentration-dependent inhibition of cell viability at the IC25, IC50, and IC75 levels of 1.027, 1.802, and 3.160 mM, respectively. Single cell gel/comet assay and atomic force microscopy assay showed that 3-MCPD significantly induced early apoptosis. In addition, 3-MCPD significantly reduced progesterone production by reducing the expression of cytochrome P450 side-chain cleavage enzyme, steroidogenic acute regulatory protein, and 3β-hydroxysteroid dehydrogenase in R2C cells. The change in steroidogenic acute regulatory protein expression was highly consistent with progesterone production. Furthermore, the mitochondrial membrane potential and cAMP significantly decreased.
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