RSC Advances
·
2015
·Vol. 5
·期 91
·74629-74637
·
IF 3.84
Yunling Gao,Jieming Shu,Cong Zhang,Xiang Zhang,Haiyan Chen,Kejian Yao
A new coumarin–quinoline based sensor 1 has been synthesized. The paramagnetic Cu2+ ion turned off the fluorescence of sensor 1 with a 1 : 1 binding stoichiometry. The resultant 1–Cu2+ complex could act in situ as an efficient “off–on” fluorescence sensor for the paramagnetic Cr3+ ion triggered by the 1 : 1 replacement of Cu2+ with Cr3+. This selective fluorescence “on–off–on” sensor was used to identify Cu2+ and Cr3+ in living breast cancer MCF-7 cells using confocal fluorescence microscopy, indicating that sensor 1 has a potential application for the selective detection of Cu2+ and Cr3+ in living cells.
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Lelin Zeng,Qin Yi,Xiaohui Peng,Zhi Huang,Bart Van der Bruggen,Yusheng Zhang,Yan Kuang,Yingnan Ma,Kewen Tang
Polymer inclusion membranes (PIMs) have much application potential for metal ion separation. However, its separation selectivity highly depends on the extractant, and new efficient extractants are difficult to develop. This work proposes another approach, i.e., adding a complexing retardant to enhance the selectivity. The impurity ion (e.g., Cu 2+ ) was retarded in the feed solution by the complexing retardant (e.g., citric acid), while the target ion (e.g., Zn 2+ ) was transported across PIM. To reveal the enhancement mechanism, a mass transfer mathematical model was established. Contrast experiments proved that the complexing retardant can significantly enhance the overall separation coefficient β overall,exp . The β overall,exp of a conventional PIM system was 61.80, while β overall,exp increased to 853.45 after the retardant was added. The effects of retardant concentration, initial pH of feed solution, membrane thickness, extractant dosage, and plasticizer dosage on the retardant-enhanced PIM system were investigated. Model calculation results agreed well with the experimental data. The maximal β overall,exp 17525.68 was obtained at the optimal separation conditions of [CA] f,0 = 0.02 M, pH f ,0 = 4.5, [H 2 SO 4 ] s ,0 = 0.5 M, and the optimal composition of the PIM casting solution, i.e., PVC : P507: DBP: THF = 0.125 g: 0.188 mL: 0.032 mL: 10 mL. Further studies indicated that the retardant mechanism was reflected in the difference increase of interfacial partition coefficients P Zn 2 + , f and P Cu 2 + , f . Finally, the optimization strategies of the separation effects for the retardant-enhanced PIM system are discussed in depth based on the simulated calculation.
✓ 已验证
DOI
高影响因子
TALANTA
·
2026
·
IF 6.7
Linying Cheng,Xiang Liu,Zixin Zhang,Jing Liu,Jianru Tang,Xiaohua Zhu,Youyu Zhang,Meiling Liu
Copper ions (Cu 2+ ) are essential micronutrients but become hazardous when accumulated in excess, necessitating reliable, sensitive, and field-deployable detection methods. Herein, we report a fluorescent Mn-based MOF nanozyme (Mn-TCPP) that exhibits intrinsic oxidase-like activity, capable of catalyzing the oxidation of non-fluorescent o -phenylenediamine (OPD) to fluorescent 2,3-diaminophenazine (DAP) with an emission peak at 560 nm, while the Mn-TCPP itself displays characteristic fluorescence at 655 nm. Upon exposure to Cu 2+ , the stronger affinity of Cu 2+ toward the porphyrinic TCPP ligand displaces Mn 2+ from the framework, forming Cu-TCPP. This metal-exchange process simultaneously quenches the 655 nm fluorescence of the MOF and attenuates its oxidase-mimicking activity, whereas free Cu 2+ in solution independently catalyzes OPD oxidation, further enhancing the 560 nm emission. Leveraging this dual-response mechanism, we develop a ratiometric fluorescence sensing strategy for Cu 2+ detection based on the intensity ratio F 560 /F 655 . The calibration curve follows a linear equation: F 560 /F 655 = 0.201x-0.001 (0.2-10 μM, R 2 = 0.985) and y = 0.002x+2.061 (10-100 μM, R 2 = 0.994) with the limit of detection (LOD) of 81 nM (S/N = 3). The sensor exhibits excellent selectivity over competing metal ions, and the method reliability is validated by standard addition recovery experiments in real water and rice samples. Furthermore, the Mn-TCPP nanozyme is embedded into an agarose hydrogel matrix, enabling visual, instrument-free monitoring of Cu 2+ contamination: increasing Cu 2+ concentrations induce a discernible fluorescence color transition from orange to yellow under 365 nm illumination. This work presents a tunable MOF platform that exploits competitive targets synchronous modulation of fluorescence and enzyme-mimicking activity, providing a robust, selective, and field-deployable ratiometric sensor for Cu 2+ .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 10.6
Yu Liu,Xue Li,Junfeng Su,Yihan Bai,Yue Wang,Xuan Li
As the complexity of industrial wastewater pollution continues to increase, the simultaneous removal of nitrogen, metal contaminants, and persistent organic pollutants under low carbon conditions has become a key challenge for biological treatment systems. To address the operational instability and dependence on carbon sources observed in immobilized systems when exposed to copper (Cu 2+ ) and bisphenol A (BPA), the Pseudoalteromonas japonicus strain LY0623 was integrated into a hydrogel-biochar-AQDS composite carrier to construct a multifunctional immobilized biofilm system. Notably, under conditions containing only NaHCO 3 , the R4 system achieved an NH 4 + -N removal rate of 89%. Under conditions where Cu 2+ and BPA coexist, the R4 system achieved removal of NH 4 + -N (89%), NO 3 - -N (100%), Cu 2+ (85%), and BPA (88%). Sediment characterization confirmed that Cu 2+ was immobilized through adsorption, complexation, and microbiologically induced carbonate precipitation (MICP). Metagenomic analysis further indicated that the Pseudomonadota phylum remained the dominant phylum, while functional pathways associated with inorganic carbon assimilation, HNAD nitrogen metabolism, endogenous carbon transformation, biomineralization, electron transfer, and aromatic compound degradation were preserved. By combining ammonia oxidation driven energy production, inorganic carbon utilization, redox mediated processes, and biomineralization, this study provides a highly promising low carbon strategy for treating industrial wastewater containing mixed pollutants.
✓ 已验证
产品关联
DOI
高影响因子
MINERALS ENGINEERING
·
2026
·
IF 6
Wentao Li,Hongxiang Xu,Erfeng Zhang,Zechao Huangfu,Jiushuai Deng
Copper site differences determine CuFeS 2 –MoS 2 flotation selectivity in Cu 2+ -containing systems. • ADT forms chelate coordination with surface Cu sites but not lattice Cu sites. • Monodentate ligands provide better CuFeS 2 –MoS 2 separation than bidentate ligands in Cu 2+ -containing systems. Interfaces involving Cu 2+ solutions play a critical role in CuFeS 2 -MoS 2 separation, and the differences among copper sites at the atomic scale are essential for understanding and controlling their separation in Cu 2+ -containing systems. Herein, sodium thioglycolate (STC) and amidinothiourea (ADT) were selected to systematically investigate the effects of copper site differences and inhibitor coordination modes on the selective separation of CuFeS 2 and MoS 2 in Cu 2+ -containing systems. The results suggest that the copper sites within the crystal lattice may be unable to form chelate rings with ADT, possibly due to geometric constraints imposed by the lattice coordination environment. In contrast, coordinated copper sites on the surface of CuFeS 2 may form chelate rings with ADT, thereby enhancing the inhibitory effect. The coordinated copper sites on the surface of MoS 2 may also exhibit a strong affinity for ADT, which hinders the selective separation of CuFeS 2 and MoS 2 . In comparison, STC exhibited a relatively weaker inhibitory effect on MoS 2 . Therefore, selecting reagents with appropriate structures may mitigate the adverse effects of Cu 2+ to some extent. These results suggest that monodentate ligand-based inhibitors containing multiple polar functional groups could be promising candidates for CuFeS 2 -MoS 2 separation in Cu 2+ systems. In addition, since Cu 2+ adsorbs more strongly to the surface of CuFeS 2 than to MoS 2 , and in combination with the control of Cu 2+ concentration, it is expected that the interference from Cu 2+ can be further reduced. This study provides new insights into the selection and design of MoS 2 -CuFeS 2 separation inhibitors in Cu 2+ -containing systems. Download: Download high-res image (300KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
Arabian Journal of Chemistry
·
2021
·Vol. 14
·期 10
·103351
·
IF 5.165
Deqiang Wang,Xin Zhou,Chong Ma,Meiying Liu,Hongye Huang,Xiaoyong Zhang,Yen Wei
Fluorescent sensor has demonstrated to be a facile and effective method to detect heavy metal ions owing to its unique characteristics such as simplicity, ease of operation and cost-effectiveness. In this work, a novel fluorescent probe with aggregation-induced emission (AIE) feature that contains an amide ligand base on the tetraphenylethylene (TPE) dye was designed and successfully synthesized. The utilization of the AIE-active fluorescent probe (named as FDPA) for detection of Cu 2+ in aqueous solution has also been examined. We demonstrated that the resultant AIE-active molecule displays amphiphilic property and can self-assemble in aqueous solution with remarkable enhancement of fluorescent intensity owing to its AIE feature. The detection limit of probe for Cu 2+ determination is 6.11 × 10 −9 M and shows excellent selectivity in the presence of competitive ions. This work provides a useful route to overcome the fluorescence quenching of conventional fluorescent probes in aqueous solution and an elegant way to prepare fluorescent probes with better fluorescence properties.
研究领域:
分析化学
·
生物医学工程
·
分子影像
·
环境毒理学
·
化学生物学
·
药物分析
·
纳米医学
✓ 已验证
DOI
高影响因子
LANGMUIR
·
2026
·
IF 3.9
Lijuan Qin,Hongshuai Gao,Chenguang Wang,Yatao Zhang,and Yi Nie
While ionic liquids (ILs) hold significant promise for diverse applications, their sustainable recycling or regeneration is hindered by the persistent challenge of removing metal-ion impurities such as Cu2+. To address this, we attempted to develop a novel polymer adsorbent, carboxyl-functionalized polymers of intrinsic microporosity (PIM-COOH) beads, for the selective separation and elucidating their underlying adsorption mechanisms. The beads not only inherited a hierarchical structure with the macropores, mesopores, and micropores, facilitating the rapid adsorption of ILs and Cu2+ within 30 min (>95% at their equilibrium capacity), but also possessed the enriched −COOH accessible sites to selectively adsorb Cu2+. A high molar adsorption capacity of Cu2+ (∼0.74 mmol/g) relative to that of ILs (∼0.05 mmol/g) at 313 K was achieved, giving a separation factor of 26.9. Mechanistic studies revealed that the hierarchical pores govern the similar mass transfer and adsorption kinetics for both species, whereas the functional sites dictate their distinct adsorption capacities and thermodynamic behaviors. Both theoretical and experimental analyses suggested that IL adsorption proceeds mainly through physical interactions (ion exchange and π–π stacking), while Cu2+ adsorption involves a combined physicochemical mechanism dominated by ion exchange and coordination.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Wei Qi,Shufang Liu,Menghao Li,Qing Su,Qiaolin Wu
Heavy metal pollution is of great threat to public health and the environment, and an effective method to detect and remove toxic heavy ions from water is highly desirable. The emerging covalent organic frameworks (COFs) with well-defined pore structures and specific functional units provide an excellent platform for fluorescent sensing. The hydrazone-linked framework material SH-COF with excellent hydrophilicity and abundant chelating sites was synthesized by bottom-up strategy under solvothermal conditions. The resultant SH-COF with specific binding sites was proposed to detect and remove Cu 2+ and Hg 2+ . The SH-COF also exhibited the characteristics of high selectivity, high sensitivity, a lower limit of detection (0.244 μM for Cu 2+ and 0.239 μM for Hg 2+ ), and real-time response. Furthermore, the highly selective interaction of Cu 2+ or Hg 2+ with SH-COF was confirmed by X-ray photoelectron spectroscopy, energy dispersive X-ray spectroscopy and Fourier transform infrared spectra. A proposed sensing mechanism of COF for Cu 2+ and Hg 2+ was presented. This research also demonstrates the great potential of COFs in practical sensing applications.
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Xiaoyan Sun,Yuxin Guo,Ruizhi Wen,Hongchang Li
Cu 2+ is a major environmental pollutant. An efficient measurement for Cu 2+ is urgently needed. In this report, we have developed a new sensitive and selective ratiometric sensing platform using 7-amino-4-methylcoumarin (AMC) for detecting Cu 2+ in real samples. In the presence of Cu 2+ , o-phenylenediamine (OPD) could be catalytically oxidized to 2,3-diaminophenazine (DAP), which could react with AMC, leading to quench the fluorescence intensity of AMC at 438 nm. Meanwhile, DAP provided a new emission peak at 557 nm. Based on the efficient overlapped spectrum of AMC and DAP, a ratiometric sensing platform through fluorescence resonance energy transfer (FRET) was carried out. Furthermore, the as-proposed strategy displayed the linear relationship in the wide range from 6 to 250 μM with a low detection limit of 0.059 μM, and the recoveries of the spiked samples in real samples ranged from 86.5% to 110.1%. Moreover, comparing the visual fluorescence colors of the real samples with the standard colorimetric card, we used the as-proposed strategy as a solid-based platform for realizing an efficient semi-quantitative detection of Cu 2+ via naked-eye visual fluorescence mode without any complicated instrument and operation. The above results implied that the as-proposed strategy could be used in the practice determination of Cu 2+ .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Ya Yuan Zhang,Qiao Jing Lin,Ding Ling Gao,Yu Xiang Liu,Na Qin,Yan Xue Xue,Fei Fei Dai,Jian Hua Chen,Qian Yang
NHC/Co-MOF-Cu 2+ composite adsorbent materials were prepared through the in-situ synthesis of nitrogenous heterocyclic compounds (NHC) on Co-containing metal–organic framework (Co-MOF) using terephthalaldehyde (C 8 H 6 O 2 ) and p-Phenylenediamine (C 6 H 8 N 2 ) at room temperature. Subsequently, further modification with Cu 2+ was carried out. These materials were then utilized for the removal of dibenzothiophene (DBT) from simulated gasoline. The samples were analyzed using scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR) and other methods. The results indicated the uniform attachment of NHC and Cu 2+ metal particles onto Co-MOF, confirming the successful synthesis of NHC/Co-MOF-Cu 2+ adsorption materials. The introduction of Cu 2+ enhanced the π-complexation between NHC/Co-MOF-Cu 2+ and DBT. The introduction of NHC brought heteroatoms and ring structures to the composite, increasing the electron cloud density of the NHC/Co-MOF-Cu 2+ composite and thereby amplifying the π-complexation with DBT. The adsorption capacity of NHC/Co-MOF-Cu 2+ for DBT (150.4 mg/g) is significantly larger than that of Co-MOF (102.5 mg/g). The adsorption process of NHC/Co-MOF-Cu 2+ for DBT followed the pseudo-second-order kinetic model and Langmuir model. Additionally, the adsorption process was found to be spontaneous and exothermic. Over five consecutive adsorption–desorption cycles, the efficiency of NHC/Co-MOF-Cu 2+ decreased by only 10 %, indicating its excellent regeneration performance.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Xingxi Feng,Jiaxiao Niu,Jiang Cao,Xue Mi,Xin Di
Triple functions: Cu 2+ coordination, CMCD inclusion and polarity switchable. • Selective for 4‑carbonyl-5-hydroxy flavonoids; baicalin yield 160 mg/g. • Higher extraction yield than conventional methods/organic solvents. • Mechanism clarified by DFT/docking/IGMH. To address the inherent limitations of conventional deep eutectic solvents, such as poor selectivity and tedious separation procedures, this study prepared a novel Cu 2+ -functionalized metal-supramolecular deep eutectic solvent (MSDES) for the efficient and highly selective extraction of flavonoids from Scutellaria baicalensis Georgi. The MSDES integrates three synergistic mechanisms: Cu 2+ coordination for specific molecular recognition, carboxymethyl-β-cyclodextrin host-guest inclusion for enhanced compatibility, and the combination of decanoic acid with N , N -dimethylcyclohexylamine for polarity-switchable phase separation. This design not only improves extraction yield but also simplifies recovery, eliminating the need for distillation. Under the optimized conditions, the extraction yield of baicalin reached 160 mg/g, which was significantly higher than those obtained with conventional DESs and organic solvents. The system was characterized by UV–Vis, 1 H NMR and FT-IR spectroscopies, and the extraction mechanism was elucidated by DFT calculations and molecular docking. This study addresses the critical issue of insufficient molecular recognition precision in conventional DESs, providing an efficient novel strategy for the extraction of bioactive components from traditional Chinese medicinal materials. Download: Download high-res image (179KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
Chemosensors
·
2023
·Vol. 11
·期 11
·556
·
IF 4.2
Juan Liu,Peng-Yu Cheng,Sai Chen,Meng Wang,Kai Wei,Yuan Li,Yao-Yao Cao,Xing Wang,Hong-Lei Li
A fluorescent probe,N′-((3-methyl-5-oxo-1-phenyl-4, 5-dihydro-1H-pyrazol-4-yl) methylene)-2-oxo-2H-chromene-3-carbohydrazide (MPMC), was synthesized and characterized. Characterizations of the synthetic MPMC were conducted via proton nuclear magnetic resonance (1HNMR) spectroscopy and carbon-13 nuclear magnetic resonance spectroscopy (13C NMR). The fluorescence emission behaviors of the MPMC probe towards diverse metal ions were detected, and the probe exhibited high sensitivity and selectivity towards Cu2+over other metal ions via the quenching of its fluorescence. Furthermore, the existence of other metal actions made no apparent difference to the fluorescence intensity of the MPMC-Cu2+system; that is, MPMC displayed a good anti-interference ability. Job’s plot of the MPMC and copper ions indicated that the detection limit was 10.23 nM (R2= 0.9612) for the assayed actions, with a stoichiometric ratio of 1:1 for MPMC and Cu2+. Additionally, the color of the MPMC probe solution changed from nearly colorless to yellow in the presence of Cu2+in visible light, and the color change could be observed by the naked eye. Similarly, the color resolved from bright yellow into blue in ultraviolet light. Moreover, reusability studies indicated that the MPMC probe was reusable. The pH effect of the MPMC probe on Cu2+had a broad range of pH detection, i.e., from 4.0 to 11.0. The response time of the MPMC probe for determining Cu2+was within 1 min. The recognition of Cu2+via MPMC performed on pre-treated paper under sunlight and UV light both had a distinct colour change. Thus, the solid-state method for detecting Cu2+with the naked eye was both economical and convenient.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）