MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 8
·1-9
·
IF 5.479
Xie Yu,Tu Xiaolong,Ma Xue,Fang Qingwen,Liu Guangbin,Dai Runying,Qu Fengli,Yu Yongfang,Lu Limin,Huang Xigen
An enzyme-free electrochemical method is described for the determination of trace levels of malathion. It is based on a nanostructured copper-cerium oxide (CuO-CeO 2 ) composite prepared by calcination of a Cu(II)/Ce(III) metal-organic framework. The morphology, crystal structure and elemental composition of composite was studied by scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The principle for malathion determination is based on the fact that the redox signal of CuO (best measured at around −0.1 V vs. SCE) (at 100 mV/s) is inhibited by malathion due to affinity between CuO and the sulfur groups of malathion. The introduction of CeO 2 into the composite system further improves the analytical performance. This is attributed to the unique microstructure and the synergistic effect between CuO and CeO 2 . Experimental parameters like solution pH value, Cu/Ce molar ratio, accumulation potential, accumulation time, and CuO-CeO 2 volume on the electrode were optimized. The assay has a linear range of 10 fM to 100 nM and a 3.3 fM detection limit (at S/N = 3). The electrode is selectively inhibited by malathion even in the presence of potentially interfering substances.
A sensitive and effective enzyme-free electrochemical sensor has been developed for the detection of malathion based on CuO-CeO 2 composite derived from bimetallic metal-organic frameworks.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Yujie Yu,Chao Yu,Rufei Gao,Jun Chen,Hangtian Zhong,Yilin Wen,Xingduo Ji,Jiahao Wu,Junlin He
We fabricate a novel electrochemical biosensor based on the specific thymine-Hg 2+ -thymine (T-Hg 2+ -T) base pair for the highly sensitive detection of mercury ions (Hg 2+ ) and utilize toluidine blue (TB) as a redox indicator that is combined with a hybridization chain reaction (HCR) for signal amplification . The dandelion-like CuO (D-CuO) microspheres that were assembled using Au nanoparticles were first introduced as support materials, which produced more active sites for the thiolated probe (P1) combination. Then, the presence of Hg 2+ induced P1 to hybridize with the other oligonucleotide (P2) through Hg 2+ -mediated T-Hg 2+ -T complexes. In addition, the partial sequence of P2 acted as an initiator sequence, which led the two hairpin DNA (H1 and H2) strands to collectively form the extended double-strand DNA through the HCR process on the electrode surface . TB was employed to interact with the double strands and produce an efficient electrochemical signal. The proposed strategy combined the amplification of the HCR and the inherent redox activity of TB and utilized D-CuO/Au composites, which exhibited high sensitivity for Hg 2+ determination. Under the optimum conditions, the proposed biosensor showed a prominent response for Hg 2+ , including a linear range from 1 pM to 100 nM and a detection limit of 0.2 pM (S/N = 3). Moreover, the new biosensor proved its potential application for trace Hg 2+ determination in environmental water samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Catalysts
·
2019
·Vol. 9
·期 9
·724
·
IF 3.444
Yan Cui,Leilei Xu,Mindong Chen,Chufei Lv,Xinbo Lian,Cai-e Wu,Bo Yang,Zhichao Miao,Fagen Wang,Xun Hu
CuO-based catalysts are usually used for CO oxidation owing to their low cost and excellent catalytic activities. In this study, a series of metal oxide (La2O3, Fe2O3, PrO2, Sm2O3, and MnO2)-doped CuO-based catalysts with mesoporous Ce0.8Zr0.2O2support were simply prepared by the incipient impregnation method and used directly as catalysts for CO catalytic oxidation. These mesoporous catalysts were systematically characterized by X-ray powder diffraction (XRD), N2physisorption, transmission electron microscopy (TEM), energy-dispersed spectroscopy (EDS) mapping, X-ray photoelectron spectroscopy (XPS), and H2temperature programmed reduction (H2-TPR). It was found that the CuO and the dopants were highly dispersed among the mesoporous framework via the incipient impregnation method, and the strong metal framework interaction had been formed. The effects of the types of the dopants and the loading amounts of the dopants on the low-temperature catalytic performances were carefully studied. It was concluded that doped transition metal oxides could regulate the oxygen mobility and reduction ability of catalysts, further improving the catalytic activity. It was also found that the high dispersion of rare earth metal oxides (PrO2, Sm2O3) was able to prevent the thermal sintering and aggregation of CuO-based catalysts during the process of calcination. In addition, their presence also evidently improved the reducibility and significantly reduced the particle size of the CuO active sites for CO oxidation. The results demonstrated that the 15CuO-3Fe2O3/M-Ce80Zr20 catalyst with 3 wt. % of Fe2O3showed the best low-temperature catalytic activity toward CO oxidation. Overall, the present Fe2O3-doped CuO-based catalysts with mesoporous nanocrystalline Ce0.8Zr0.2O2solid solution as support were considered a promising series of catalysts for low-temperature CO oxidation.Keywords:CuO-based catalyst;Fe2O3dopant;mesoporous Ce0.8Zr0.2O2solid solution;low-temperature catalytic activity;CO oxidation
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 9
·1-7
·
IF 5.479
Zhang Bing,Jia Yejing,Wang Jing,Hu Xing,Zhao Zhihuan,Cheng Yan
A sensitive photoelectrochemical (PEC) immunoassay for the carcinoembryonic antigen (CEA) is described that is based on the use of C 3 N 4 -BiOCl semiconductor on an ITO electrode. The photocurrent of the modified electrode was measured under visible light illumination. It increased in presence of L-cysteine due to rapid separation of the photoexcited electrons and holes. A sandwich-type immunoassay in a 96-well microtiter plate format used CuO nanoparticles as label for the secondary antibody. The Cu 2+ is released from the CuO in the sandwich complex by treatment with acid. The free Cu 2+ combined with both the cysteine and the electron receptors of C 3 N 4 and BiOCl. Under optimal conditions, this dual action immensely decreases the photocurrent of the PEC system, and the response is inversely proportional to the CEA concentrations from 0.1 pg mL −1 to 10 ng mL −1 at the working voltage of 0 V (vs. SCE). The detection limit is 0.1 pg mL −1 , and the method is exhibited satisfactory selective, repeatable and stable.
Schematic representation of an immunoassay based on cysteine-assisted C 3 N 4 -BiOCl photoelectrochemical platform. CuO nanoparticles were utilized as labels in immunocomplex to release Cu 2+ in acidic condition. Carcinoembryonic antigen in sample was detected sensitively by dual function of Cu 2+ with cysteine and C 3 N 4 -BiOCl semiconductor.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Weigang Cui,Churu Zhang,Shuangjiang Li,Yi Liu,Long Tian,Mengrui Li,Yunfei Zhi,Shaoyun Shan
In this study, copper oxide (CuO) was prepared by the microwave-assisted hydrothermal technique subsequently, CuO was grown in situ onto different rare metal compounds to prepare Z-scheme heterojunctions to improve the degradation efficiency of tetracycline (TC) in water environments. Various characterization proved the successful synthesis of all composite materials, and the formation of tight heterojunction interfaces, among which, the core–shell structure ZnIn 2 S 4 @CuO exhibited excellent photocatalytic degradation capability. Research results indicated that the degradation efficiency of ZnIn 2 S 4 @CuO for TC (50 mg/L) in the water environment reached 95.8 %, and the degradation rate is 2.41 times and 12.93 times that of CuO and ZnIn 2 S 4 alone, respectively, the reason is because of the introduction of ZnIn 2 S 4 , Z-scheme heterojunction structures and internal electric field (IEF) is constructed and formed to extend the visible light response range of photocatalysts to improve electron-hole separation efficiency, and enhance charge transfer. In addition, ZnIn 2 S 4 @CuO-2 exhibited good stability and reproducibility, with no significant loss of activity after five cycles. Finally, the precise locations of free radical attack on TC were investigated by the combined use of high-resolution mass spectrometry (HR-MC) and frontier electron densities (FEDs), and a reasonable degradation pathway was provided. The results of this research provide a new and viable approach to overcome the limitations of conventional photocatalytic materials in terms of limited visible light absorption range and fast carrier recombination rates, which offers promising prospects for a wide range of applications in the field of wastewater purification.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WATER RESEARCH
·
2022
·
IF 13.4
Jun Hu,Jiajia Qu,Lin Deng,Huiyu Dong,Liying Jiang,Jianming Yu,Siqing Yue,Haifeng Qian,Qizhou Dai,Zhimin Qiang
Cupric oxide (CuO) is able to catalyze the reactions among disinfectant, extracellular polymeric substances (EPS) and bromide (Br − ) in copper pipes, which may deteriorate the water quality. This study aimed to investigate the metabonomic and transcriptomic modulations of HepG2 cells caused by the CuO-catalyzed formation of disinfection byproducts (DBPs) from EPS. The presence of CuO favored the substitution reactions of chlorine and bromine with EPS, inducing a higher content of total organic halogen (TOX). In addition, DBPs were shifted from chlorinated species to brominated species. A total of 182 differential metabolites (DMs) and 437 differentially expressed genes (DEGs) were identified, which were jointly involved in 38 KEGG pathways. Topology analysis indicates that glycerophospholipid and purine metabolism were disturbed most obviously. During glycerophospholipid metabolism, the differential expression of genes GPATs, AGPATs, LPINs and DGKs impacted the conversion of glycerol-3-phosphate to 2-diacyl- sn -glycerol, which further affected the conversion among phosphatidylcholine, phosphatidylserine and phosphocholines. During purine metabolism, it was mainly the differential expression of genes POLRs, RPAs, RPBs, RPCs, ENTPDs and CDs that impacted the transformation of RNA into guanine-, xanthosine-, inosine- and adenosine monophosphate, which were further successively transformed into their corresponding nucleosides and purines. The study provides an omics perspective to assess the potential adverse effects of overall DBPs formed in copper pipes on human.
✓ 已验证
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2019
·
IF 5.589
Xiaojing Zhang,Zhao Chen,Yongpeng Ma,Nan Zhang,Denghui Wei,Hongli Zhang,Hongzhong Zhang
Considering the inevitable release of antibiotics and nanoparticles (NPs) into the nitrogen containing wastewater, the combined impact of CuO NPs and sulfamethoxazole (SMX) antibiotic on partial nitrification (PN) process was investigated in four identical reactors. Results showed that the bioactivity of the aerobic ammonia-oxidizing bacteria (AOB) decreased by half after they were exposed to the combination of CuO NPs and SMX for short-term; however, there was no obvious variation in the bioactivity of AOB when they were exposed to either CuO NPs or SMX. During long-term exposure, the ammonia removal efficiency (ARE) of CuO NPs improved whereas that of SMX decreased, while the combination of CuO NPs and SMX significantly decreased ARE from 62.9% (in control) to 38.2% and had an unsatisfactory self-recovery performance. The combination of CuO NPs and SMX significantly changed the composition of microbial community, decreased the abundance of AOB, and significantly suppressed PN process. Reegarding the resistance genes, the CuO NPs-SMX combination did not improve the expression of copA , cusA , sul1 and sul2 ; however, it significantly induced the expression of sul3 and sulA .
✓ 已验证
DOI
PubMed
高影响因子
FUEL
·
2017
·
IF 4.601
Dongjing Liu,Weiguo Zhou,Jiang Wu
CuO-based and MnO x -based sorbents modified with Ce and La using sol-gel method, were employed for elemental mercury removal at 120–240 °C. The Hg 0 removal activity of Mn 2 O 3 /ZSM-5 can be significantly enhanced by doping 50 at.% Ce or 10 at.% La, the Hg 0 removal efficiency increased by 94% and 71%, respectively. The Hg 0 removal ability of CuO/ZSM-5 subtly improved by addition of 50 at.% Ce or 10 at.% La, the Hg 0 removal efficiency ascended only by 6% and 18%, respectively. The XPS results revealed that Hg 0 transformed to HgO, and CuO (or Mn 2 O 3 ) was reduced to Cu 2 O (or Mn 3 O 4 ), which is in agreement with Mars-Maessen mechanism.
✓ 已验证
DOI
高影响因子
ACS Sensors
·
2025
·
IF 9.1
Yaming Hu,Wenshuo Xie,Zhizhi Wang,Jinlong Ma,Linlin Hou,Qi Wang,Feng Xiong,Guanglan Liao,Tielin Shi,Hu Long
The introduction of oxygen vacancies (OVs) into metal oxide micro/nanostructures significantly enhances both catalytic performance and electrical conductivity, thereby boosting their gas-sensing capabilities. However, conventional approaches for engineering oxygen vacancies typically require specialized equipment (e.g., autoclave reactors) and extreme operational conditions (e.g., high temperature and high vacuum), posing substantial challenges for practical applications. Herein, a novel single-step laser-induced technique is developed for fabricating CuOx-based room-temperature acetone sensors under ambient conditions. The technique enables mask-free fabrication of tunable sensing films spanning morphologies from porous networks to nanospheres by precisely modulating the film thickness. Furthermore, oxygen-vacancy self-doping is inherently coupled with the micro/nanostructure growth mechanism, bypassing conventional postsynthesis treatments while preserving process simplicity. The as-prepared CuOx gas sensors with distinct morphologies manifest exceptional room-temperature acetone sensing with a wide response range spanning 0.1–10 ppm. Comparative analysis of nanosphere-based gas sensors conclusively demonstrates that oxygen vacancies constitute a key structural determinant, enabling room-temperature sensing capability in CuOx-based sensors. Moreover, both gas sensors exhibit outstanding selectivity toward acetone against common interferents (NO2, H2, CO2, and CO) and a low detection limit, highlighting their potential for trace acetone gas detection applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Haoheng Wu,Yanyan Yu,Ying He,Yun Liu
The development of high-performance, multifunctional catalysts capable of effectively addressing nitroarene hydrogenation remains a significant challenge. In this study, we present a novel approach to catalyst design through the controlled carbonization of a copper–furan dicarboxylate metal–organic framework (Cu-FDCA MOF), resulting in two distinct nanocomposites: oxygen-vacancy-rich Cu/Cu 2 O/CuO@C (synthesized in an argon atmosphere) and conventional CuO (prepared by air calcination). Advanced characterizations, including TEM, XPS, EPR, and BET, reveal that Cu/Cu 2 O/CuO@C possesses 2.3 times more oxygen vacancies and a surface area 97 times greater (106.21 m 2 /g vs. 1.09 m 2 /g) than CuO, which directly correlates with its superior catalytic performance. In the context of nitroarene hydrogenation, Cu/Cu 2 O/CuO@C demonstrates an exceptionally high rate constant (k app = 25.33 × 10 -2 s -1 ), outperforming CuO by a factor of 40. Furthermore, Cu/Cu 2 O/CuO@C maintains 90 % of its catalytic activity after five reaction cycles and can be fully regenerated upon treatment at 400 °C. Through a combination of experimental studies and density functional theory (DFT) calculations, we propose a novel water-derived hydrogen transfer mechanism that challenges conventional understanding of the role of NaBH 4 . Notably, Cu/Cu 2 O/CuO@C also exhibits impressive versatility, efficiently degrading organic dye (Congo red/methylene blue/methyl blue) within three minutes. This work establishes MOF-derived oxygen-deficient nanocomposites as promising platforms for both amine synthesis and environmental decontamination.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2026
·Vol. 61
·期 35
·26387-26402
·
IF 4.4
Cai Shenao,Yang Yurui,Yao Lirong,Xu Sijun,Zhang Chengjiao
Traditional copper oxide nanoparticles (CuONPs) for antimicrobial textiles face significant challenges. First, the synthesis is reagent-intensive, requiring hazardous substances such as sodium hydroxide. Second, the resulting CuONPs usually exhibit poor aqueous dispersibility and low affinity for fabrics. Herein, an amino-terminal hyperbranched poly(amide–amine) and Cu 2+ complex (HBPAA-Cu 2+ ) was developed. This complex can be coated to cotton fabric via a conventional dipping-rolling-drying process and converted in situ into HBPAA-capped CuONPs (HBPAA-CuO) through thermal oxidation. This approach avoided the need for additional alkaline precipitants and surfactants during the formation of CuO and was expected to reduce the amount of CuONP-containing wastewater generated compared to conventional wet-chemical synthesis routes. Owing to the combined effect between the antimicrobial cationic HBPAA and the CuONPs, no colonies of E. coli and S. aureus were detected for the treated fabric even after 50 laundering cycles (Cu content > 100 mg/kg). Furthermore, cell viability remained above 80% with Cu content below 300 mg/kg, indicating low cytotoxicity. The treatment also preserved the fabric’s original wearability, including tensile strength, air permeability, and flexural stiffness. This strategy offers a facile and sustainable pathway for the large-scale production of washable, low-cytotoxicity, and antimicrobial textiles.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 3
·1-10
·
IF 6.408
Xu Yaxin,Li Peipei,Zhu Yu,Tang Ying,Chen Haoyu,Zhu Xiaohua,Wu Cuiyan,Zhang Youyu,Liu Meiling,Yao Shouzhuo
A novel nanocomposite of CuO nanoparticle-modified Zr-MOF (CuO/UiO-66) was synthesized and developed as a fluorescence nanoplatform for H 2 O 2 and adenosine triphosphate (ATP) via the “turn-on–off” mode in the presence of terephthalic acid (TA). The structure of CuO/UiO-66 was thoroughly characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques. The CuO/UiO-66 with enhanced peroxidase-like (POD) activity obtained due to the Zr 4+ in UiO-66 is beneficial to the aggregation of CuO NPs on its surface. As a result, the strengthened fluorescence at 425 nm with the excitation of 300 nm was found due to the highly fluorescent species of TAOH. This is produced by the oxidation of TA by ·OH that came from the catalysis of H 2 O 2 via the peroxidase mimic of CuO/UiO-66. Hence the modification of CuO NPs on porous UiO-66 can provide a friendly and sensitive physiological condition for H 2 O 2 detection. However, upon addition of ATP, the fluorescence intensity of TAOH at 425 nm effectively declined owing to the formation of complexation of Zr 4+ -ATP and the interaction of CuO to ATP which hampers the catalytic reaction of CuO/UiO-66 to H 2 O 2 . The specific interaction induced “inhibition of the peroxide-like activity” endows the sensitive and selective recognition of ATP. The detection limits were 16.87 ± 0.2 nM and 0.82 ± 0.1 nM, and linear analytical ranges were 0.02–100 μM and 0.002–30 μM for H 2 O 2 and ATP, respectively. The novel strategy was successfully applied to H 2 O 2 and ATP determination in serum samples with recoveries of 97.2–103.8% for H 2 O 2 and 97.6–101.7% for ATP, enriching the avenue to design functional MOFs and providing new avenue of multicomponent bioanalysis. Graphical abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）