Small
·
2025
·
IF 12.1
Yue Wang,Liguo Jin,Chaofeng Wang,Hanpeng Liu,Congyang Mao,Xiangmei Liu,Zhaoyang Li,Shengli Zhu,Hui Jiang,Zhenduo Cui,Yufeng Zheng,Shuilin Wu
Osteomyelitis caused by Staphylococcus aureus ( S. aureus ) is difficult to cure with antibiotics or phototherapy. Microwave (MW) has become a promising method for treating deep tissue infections due to its strong penetration ability, however, the effects of MW dynamics still need to be improved to achieve rapid and effective treatment. In this work, tin selenide/polypyrrole (SnSe/PPy) nanocomposites with MW thermoelectric catalytic performance are successfully prepared, and their ideal thermal production capability stems from increased dielectric loss, including interfacial polarization and conductive loss, as well as magnetic loss. Furthermore, the enhanced interchain electronic transport of PPy and the phonon scattering effect have improved the thermoelectric performance of SnSe/PPy. Under MW cyclic irradiation, SnSe/PPy can convert the generated temperature difference into electrical energy and further promote the ionization of sodium species, the plasma and electrons react with O 2 to produce superoxide anion (·O 2 − ), enabling SnSe/PPy to rapidly increase the temperature and effectively eliminate S. aureus infection. After irradiated circularly by MW for 20 min, the antibacterial effect of SnSe/PPy can reach 99.46 ± 0.11%. Considering the remarkable antibacterial effectiveness and excellent biosafety, it is believed that it provides new insights into the design of MW thermoelectric catalysis antimicrobial materials.
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LANGMUIR
·
2024
·
IF 3.7
Zhi Li,Minglong Sun,Yalin Li,Ziang Liu,Dongxiang Zhang,Yingmin Liu,Xinghui He,Mo-Jie Sun
Metal–organic frameworks (MOFs) are crystalline porous materials for storage and energy conversion applications with three-dimensional pore structure, high porosity, and specific surface area, which are widely utilized in electrocatalysis. Herein, MoSe2/NiSe composites were synthesized by selenization reaction using NiMOF as the precursor. The composites were hollow nanoflower structures with a synergistic effect between MoSe2 and NiSe to promote rapid electron transfer, which exhibited good hydrogen evolution reaction performance in an alkaline medium. At a current density of 10 mA/cm2, the HER overpotential reaches 80 mV, the Tafel slope is 33.86 mV/dec, and the material has good stability, with polarization curves remaining essentially unchanged after 3000 cycles. These results indicate that the method has a promising application in the preparation of efficient and sustainable catalysts for hydrogen production in alkaline medium.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
·
IF 8.1
Wenyue Jiang,Bingxin Zhao,Ziting Li,Peng Zhou,Yuxin Zhao,Xiaoshuang Chen,Jinping Wang,Rui Yang,Chunling Zuo
The investigation of cost-effective and highly efficient electrocatalysts for alkaline water and simulative seawater oxidation is essential to the conversion and storage of renewable energy . In this paper, the Ce–NiSe 2 /CoP catalyst with multihole and ultrathin nanosheet structure is generated. The unique structural characteristics of Ce–NiSe 2 /CoP heterojunction nanosheets contribute the excellent OER performance under different alkaline 1 M KOH and simulated seawater (1 M KOH + 0.5 M NaCl) electrolytes. Specifically, this catalyst exhucture is generated. The unique structural characteristics of Ce–NiSe 2 /CoP heterojunction nanosheets conibits the low overpotentials of 287 and 304 mV at the current density of 10 mA cm −2 , along with the Tafel slopes of 87.1 and 78.8 mV dec −1 in two solutions, respectively. Moreover, the Ce–NiSe 2 /CoP target product also displays good stability. The present study introduces a promising strategy for the advancement of high-performance electrocatalysts in green energy field.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Danyang He,Liyun Cao,Jianfeng Huang,Xiaoyong Zhang,Changcong Wang,Kaikai Zhao,Koji Kajiyoshi,Liangliang Feng
Developing highly active and stably non-precious metal electrocatalysts for hydrogen production in alkaline conditions is of paramount importance to hydrogen economy. Herein, nanosheet-assembled hollow nitrogen-doped carbon nanospheres confined with ultrasmall NiSe nanoparticles (NiSe@NC) are synthesized by employing a SiO 2 template-assisted approach. As expected, the as-prepared NiSe@NC electrocatalyst delivers an overpotential of 169 mV at the current density of 10 mA/cm 2 without iR -correction, and sustains at least 80 h for continuous operation, far outperforming the NiSe-p catalyst in 1 M KOH medium toward hydrogen evolution reaction (HER). The appealing HER performance is mainly ascribed to the synergy effect between hollow nitrogen-doped carbon and highly active NiSe nanoparticles, which improves catalytically active sites, expedites electron transfer rate and optimizes the electronic structure of NiSe@NC nanomaterial. More strikingly, this study presents the feasible insights for constructing robust cost-effective electrocatalysts towards efficient HER in harsh alkaline media.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
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IF 9.7
Hongxiu Yin,Ying Gao,Xue Zhou,Xiangjun Chen,Zhichao Hu,Lingyu Zhang,Lu Li,Chungang Wang
The oral administration of drugs for cancer therapy can maintain optimal blood concentrations, is biologically safe and simple, and is preferred by many patients. However, the complex lumen environment, mucus layer, and intestinal epithelial cells are biological barriers that hinder the absorption of orally administered drugs. In this study, sea urchin-like manganese-doped copper selenide nanoparticles (Mn-Cu 2−x Se NPs) were designed using an anion exchange method and coated with calcium alginate and chitosan (AC) to form Mn-Cu 2−x Se@AC capsules. The pH-responsive swelling behavior of the AC protective layer aided doxorubicin (DOX)-loaded Mn-Cu 2−x Se NPs in overcoming multiple biological barriers, maintained their stability in gastric acid, and facilitated the release of the NPs in the small intestine. The intestinal epithelial cell permeability of DOX/Mn-Cu 2−x Se NPs was confirmed using a monolayer absorption model involving Caco-2 human epithelial cells. The released DOX/Mn-Cu 2−x Se NPs smoothly passed through the mucus layer, and were absorbed by intestinal epithelial cells. In mice, the NPs circulated in the blood and passively targeted the tumors through blood circulation by enhancing the permeability and retention effect to achieve significant tumor suppression and reduce damage to normal tissues. In addition, the unique sea urchin-like morphology of Mn-Cu 2−x Se NPs enhanced the absorption in the near-infrared-II (NIR-II) window for photothermal therapy, realized the near-infrared-stimulated response release of DOX for increased chemotherapy, and promoted the Fenton-like effect because of the doping of manganese ions for chemodynamic therapy. These effects could permit the development of various synergistic cancer treatments. The use of DOX/Mn-Cu 2−x Se@AC capsules as a multistage oral drug delivery system may overcome the sequential absorption barriers that currently hinder chemotherapy, chemodynamic, and photothermal therapies.
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Materials
·
2024
·Vol. 17
·期 7
·1509
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IF 3.1
Fan Xie,Zhiyao Ma,Jian Zhou
In addressing the global need for sustainable energy conversion, this study presents a breakthrough in thermoelectric materials research by optimizing the Bi2O2Se1–xTexsystem in the Bi2O2Se/Bi2O2Te pseudobinary series. Leveraging the principles of innovative transport mechanisms and defect engineering, we introduce tellurium (Te) doping into Bi2O2Se to enhance its thermoelectric properties synergistically. With the help of various advanced characterization tools such as XRD, SEM, TEM, XPS, FTIR, TGA, LFA, and DSC, combined with relevant resistance and density measurement techniques, we conducted an in-depth exploration of the complex interactions between various factors within thermoelectric materials. We recognize that the balance and synergy of these factors in the thermoelectric conversion process are crucial to achieving efficient energy conversion. Through systematic research, we are committed to revealing the mechanisms of these interactions and providing a solid scientific foundation for the optimal design and performance enhancement of thermoelectric materials. Finally, the advantage coefficient (ZT) of the thermoelectric material has been significantly improved. The crystallographic analysis confirms the formation of a continuous series of mixed crystals with varying Te concentrations, adhering to Vegard’s law and exhibiting significant improvements in electrical and thermal conductivities. The Bi2O2Se1–xTexcrystals, particularly the Bi2O2Se0.6Te0.4composition, demonstrate a peak ZT of 0.86 at 373 K. This achievement aligns with recent advancements in defect-enabled mechanisms and band convergence and sets a new standard for high-performance thermoelectrics. The study’s findings contribute significantly to the ongoing quest for efficient thermal-to-electrical energy conversion, offering a promising avenue for future sustainable energy technologies.
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Applied Materials Today
·
2024
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IF 7.2
Jingyue Wang,Yilei Ding,Jianan Liu,Yian Chen,Yuanfeng Wang,Ansha Zhao
While revascularization is acknowledged as a critical process in wound healing, the scenario becomes more complex when considering diabetic wounds. In such cases, oxidative stress introduces two primary challenges that impede the healing process: ensuring the directional movement of functional cells to the wound site and combating the heightened risk of infection. These challenges underscore the need for innovative therapeutic strategies that can effectively address these restrictions in the context of diabetic wound healing. Hydrogen sulfide (H 2 S) acts as a signaling gas and shows significant therapeutic potential in biomedical research. In this study, we encapsulate Allicin, a natural H 2 S donor, in selenium micelles that specifically respond to oxidative stress. To create the GMA (Allicin@Micelle-GelMA) Composite hydrogel system, we utilize Methacrylic anhydride gelatin (GelMA) hydrogel as a matrix and form it through in-situ light curing. This composite system effectively addresses the problem of healing deep, narrow, and lengthy wounds that pose a challenge, as well as preventing nonspecific sudden release of H 2 S. Additionally, the composite hydrogel system promotes angiogenesis, anti-inflammatory, antibacterial, and antioxidant properties. It also facilitates the directional movement of stem cells and macrophages, as demonstrated through the chicken embryo chorioallantoic membrane vascular test and the establishment of a diabetes wound model that is difficult to heal. Consequently, we conclude that the GMA composite hydrogel has the potential to serve as a versatile skin wound dressing that can effectively respond to oxidative stress.
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Journal of Energy Chemistry
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2018
·
IF 3.886
Yanghui Deng,Cui Ye,Guo Chen,Baixiang Tao,Hongqun Luo,Nianbing Li
Hydrogen evolution reaction (HER) is a prospective method to generate pure hydrogen. The development of superior electrocatalysts based on earth-abundant materials, plays a critical role in the future. CoSe 2 , one of the earth-abundant electrocatalysts, has been proved to be a promising catalyst for hydrogen generation . In our work, flower-like CoSe 2 nanorods with high quality are successfully synthesized through a facile ethylenediaminetetraacetic acid ligand (EDTA)-assisted hydrothermal process. The flower-like CoSe 2 nanorods show the brilliant electrochemical HER performance with 100 mA cm −2 at overpotential of 273 mV, a small Tafel slope of 35 mV dec −1 and strong durability in acid solution. The sparkly HER catalytic activity of CoSe 2 can be ascribed to its particular structure with large surface area and abundant active sites. Therefore, this work offers an outstanding candidate for improving hydrogen production capabilities by water electrolysis .
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JOURNAL OF POWER SOURCES
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2017
·
IF 6.395
Jiabin Qi,Hao Xiong,Gang Wang,Huaqing Xie,Wei Jia,Qinghong Zhang,Yaogang Li,Hongzhi Wang
Crystallization and interface engineering of perovskite are the most important factors in achieving high-performance perovskite solar cells (PSCs). Herein, we construct an ultrathin CdSe quantum dots (QDs) underlayer via a solution-processable method, which acts as a seed-mediated layer for perfect perovskite film, with both uniform morphology and better absorption capacity . In addition, CdSe QDs and perovskites form a fully crystalline heterojunction , which is beneficial to minimizing the defect and trap densities . Then, an Ostwald ripening process is adopted to fabricate large-grain, pinhole-free perovskite thin film , by a simple methylammonium bromide treatment. Besides, the first principle is applied in calculating organic/inorganic hybrid perovskite, confirming that electrons can move even quicker and more effectively, as a result of our work. Due to these treatments, representing a very simple method to simultaneously control perovskite crystallization and optimize the interfaces in PSCs, a maximum power conversion efficiency of 15.68% is achieved, 35% higher than the PSC both without CdSe and MABr treatment (11.57%), indicating better performance.
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ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Xianwen Wang,Fei Li,Xu Yan,Yan Ma,Zhao-Hua Miao,Liang Dong,Huajian Chen,Yang Lu,Zhengbao Zha
Large-size-induced long-term retention in the body has hampered the translational applications of many reported nanomedicines. Herein, we reported a multifunctional theranostic agent composed of ultrasmall poly(acrylic acid)-functionalized Ni0.85Se nanoparticles (PAA–Ni0.85Se NPs), which were successfully obtained through a facile ambient aqueous precipitation strategy. Without exhibiting any noticeable toxicity, the as-prepared PAA–Ni0.85Se NPs (average diameter of 6.40 ± 1.89 nm) showed considerable absorption in near-infrared (NIR) region and high photothermal conversion efficiency of 54.06%, which could induce remarkable photoacoustic signals for tumor imaging and heat for localized ablation of cancerous cells upon exposure to NIR light. Notably, the ultrasmall PAA–Ni0.85Se NPs, unlike conventional nanomaterials with larger sizes, showed reasonable body clearance within 8 h after intravenous injection. Furthermore, ascribed to protonation process of amino groups in DOX molecules and carboxyl groups in PAA molecules in an acidic microenvironment, the drug-loaded (doxorubicin hydrochloride, DOX·HCl) PAA–Ni0.85Se NPs (PAA–Ni0.85Se–DOX NPs) revealed promoted drug release at acidic pH, which could be useful for acidic tumor microenvironment responsive drug delivery. Evident from the results of cell-killing assay in vitro and tumor treatment study in vivo, PAA–Ni0.85Se–DOX NPs exhibited evident synergistic effects on killing 4T1 breast cancer cells. Thus, this study presents a multifunctional theranostic agent composed of ultrasmall PAA–Ni0.85Se NPs for potential cancer treatment without long-term toxicity concerns.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2018
·
IF 3.997
Xijian Liu,Yeying Wang,Qiyang Yu,Guoying Deng,Qian Wang,Xinhui Ma,Qiugen Wang,Jie Lu
A multifunctional selenium nanocomposite (selenium@silica core-shell nanoshperes for loading indocyanine green(ICG)/Doxorubicin(DOX)) was fabricated to reach visible and efficient cancer treatment. The Se@SiO 2 -ICG nanocomposites could be used not only as excellent photothermal agents but also as carriers for DOX delivery. In addition, the Se@SiO 2 -ICG/DOX nanocomposites exhibited excellent fluorescence imaging and infrared imaging performance. Tumor could be effectively inhibited by Se@SiO 2 -ICG/DOX due to the triple treatment of photothermal effect and chemotherapy of selenium and DOX. Thus, the Se@SiO 2 -ICG/DOX nanocomposites have a great potential in imaging guiding synergistic treatment of cancer.
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BIOSENSORS & BIOELECTRONICS
·
2017
·
IF 7.78
Yu-ping Wei,Xing-Pei Liu,Chang-jie Mao,He-Lin Niu,Ji-Ming Song,Bao-Kang Jin
An electrochemical biosensor was developed based on a steric hindrance hybridization assay to allow the highly sensitive detection of streptavidin . In the steric hindrance hybridization assay, the signaling strand DNA (sig-DNA) was labeled at the 3′ end with CdSe quantum dots (QDs) and at the 5′ end with biotin , and capturing strand DNA (the complementary strand of sig-DNA) was labeled at the 5′ end with thiol. The steric hindrance effect generated by streptavidin which was bound with the signaling DNA strand. The streptavidin limited the ability of the sig-DNA to hybridize with the cap-DNA, which were linked on the surface of a gold electrode. Therefore, the concentration of streptavidin was detected indirectly based on the concentration of CdSe QDs on the electrode surface . The concentration of CdSe QDs on the electrode surface was detected by differential pulse anodic stripping voltammetry . Under optimal conditions, the streptavidin detection range using the as-prepared biosensor was 1.96 pg/mL to 1.96 µg/mL and the detection limit was 0.65 pg/mL. The experimental results showed that the electrochemical biosensor could detect streptavidin rapidly and accurately.
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