NEW JOURNAL OF CHEMISTRY
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2026
·
IF 2.6
Tao Zhou,Kun-Lang Lu,Tao Li,Rui Xiao
Decoupled water splitting offers a safe and efficient route for hydrogen production. However, its practical application remains constrained by issues such as low electrode discharge capacity and poor structural stability. In this study, framework-integrated Ni(OH)2 anodes for membrane-free decoupled water splitting are fabricated. The framework-integrated electrode structure with a carboxymethyl cellulose-based binder affords a well-developed conductive network and robust interfacial contact. This architecture delivers higher discharge capacity and enhanced cycling stability relative to conventional coated electrodes. In addition, the use of nickel powder as the conductive additive improves electronic conductivity, resulting in higher discharge capacity and excellent hydrogen-production performance. The framework-integrated Ni(OH)2 anode maintains a stable structure and electrochemical performance over 100 decoupled cycles, achieving a Faradaic efficiency of 97.3%. The electrical energy consumption for hydrogen production is 3.40 kWh m-3 H2 at 50 mA cm-2.
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高影响因子
CORROSION SCIENCE
·
2026
·
IF 10.3
Changli Fu,Donald B. Dingwell,Hairong Mao,Pengfei Wei,Wenjia Song
Gd 2-x Zr 2+x O 7+x/2 ceramics were used to determine how nonstoichiometry in ceramic phases governs CMAS corrosion. All compositions retained a fluorite average structure, but Raman spectroscopy, sintering behaviour and grain growth revealed composition-dependent non-stoichiometry-driven disorder before CMAS contact. During heating, characteristic CMAS spreading temperatures depended only slightly on nonstoichiometric composition, whereas spreading rate and final spreading extent vary markedly with nonstoichiometry. After exposure at 1300 °C, all samples developed a dense inner layer and a fully reacted layer, following approximately linear and square-root time dependences of layer thicknesses, respectively. All nonstoichiometric ceramic compositions outperformed the stoichiometric composition, but the mechanistic origins of these effects were distinctly different depending on the type of nonstoichiometry, defined by different reaction products and layer-specific chemical partitioning. CMAS resistance is therefore strongly influenced by how nonstoichiometry directs competition between corrosion layers.
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高影响因子
TETRAHEDRON
·
2026
·
IF 2.1
Long Yao,Nan Wang,You Zi
A general and mild strategy for the regioselective synthesis of N-alkenyl 2-pyridones via N–C(β) bond formation is reported. Using readily available β-iodovinylsulfones as alkenylating agents, the reaction affords a diverse array of products in moderate to high yields with moderate to excellent Z -selectivity. Various 2-pyridones and β-iodovinylsulfones bearing different functional groups are well tolerated. Notably, this protocol provides an alternative to conventional N–C(α) bond-forming approaches. Gram-scale experiments demonstrate the practical applicability and scalability of this transformation.
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2026
·
IF 9.2
Shuhua Li,Yaxing Li,Shilin Liu,Hao Ye,Yuxiu Wang,Yu Xie,Jiansheng Zhang
ZnIn 2 S 4 is a highly promising photocatalyst, but its rapid carrier recombination remains the core bottleneck. Constructing band-matched heterojunctions to promote charge separation is currently the most effective strategy to address this issue. Herein, a Co 3 (PO 4 ) 2 /ZnIn 2 S 4 (CPO/ZIS) type-II heterojunction photocatalytic system is designed. The intimate coupling between CPO and ZIS is achieved via electrostatic self-assembly. Studies show that this system follows a type-II charge transfer mechanism, and owing to the strong affinity of phosphate groups for protons in aqueous solution and the electron-trapping function of cobalt active centers, the hydrogen production efficiency is synergistically enhanced. The optimal 10-CPO/ZIS composite achieves a HER of 8.87 mmol g −1 h −1 , which is 8.53 times that of pristine ZIS, and also exhibits excellent photocorrosion resistance.
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高影响因子
Journal of Energy Chemistry
·
2026
·
IF 15.6
Shuangting Ren,Tian Han,Ruijing Zhang,Ruimin Xing,Rohit Jasrotia,Hamid Zouggari,Abdallah Albourine,Shanhu Liu
Alkaline hydrogen evolution reaction (HER) is constrained by the Sabatier principle, making it challenging to simultaneously optimize water dissociation and hydrogen desorption. Here, we report a spatially decoupled tandem catalyst, Co(OH) 2 @Mo 2 C, that circumvents this constraint via a hydroxyl-mediated hydrogen spillover pathway. Mo 2 C serves as the *H generation site via rapid water dissociation, while adjacent Co(OH) 2 functions as the *H acceptor and recombination center, with abundant surface hydroxyl groups on Co(OH) 2 accelerating hydrogen spillover from Mo 2 C to Co(OH) 2 and sustaining water dissociation kinetics. CH 3 I poisoning experiments, corroborated by in situ Raman spectroscopy and density functional theory calculations, reveal the critical mediating role of hydroxyl groups in hydrogen migration. The optimized catalyst achieves only 43 mV overpotential to reach 10 mA cm −2 in 1 M KOH, and durability over 150 h at 0.5 A cm −2 in an anion exchange membrane water electrolyzer. This work establishes a generalizable interfacial engineering strategy to circumvent the Sabatier limitation by accelerating hydrogen migration on spatially segregating elementary steps. A spatially decoupled Co(OH) 2 @Mo 2 C tandem electrocatalyst shows that Mo 2 C rapidly dissociates water while Co(OH) 2 efficiently shuttles *H to accelerate H 2 release, where Co(OH) 2 abundant surface hydroxyl groups accelerate hydrogen spillover from Mo 2 C to Co(OH) 2 and maintain water dissociation kinetics. Download: Download high-res image (179KB) Download: Download full-size image
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2026
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IF 6.7
Zheng Bian,Jiaxin Xiong,Bowen Li,Cailian Wang,Chunyang Wang,Benzhong Zhu
Abstract Tomato fruit ripening is a critical developmental process that determines the fruit quality. However, the regulatory mechanisms underlying the ripening initiation remain incompletely understood. Here, we characterized SlVTE3(2), a tocopherol-biosynthesis-related methyltransferase, and investigated its role in tomato fruit ripening. CRISPR/Cas9-mediated mutation of SlVTE3(2) accelerated ripening initiation, resulting in earlier ethylene production, faster softening, and an earlier color transition, whereas overexpression delayed these processes. Transcriptome analysis showed that SlVTE3(2) affected multiple ripening-related pathways, including ethylene biosynthesis and signaling, carotenoid metabolism, and cell wall modification. Although SlVTE3(2) significantly altered the tocopherol composition in tomato fruits, exogenous tocopherol treatment did not affect ripening initiation. These findings provide new insights into the regulation of tomato fruit ripening by the metabolic enzymes.
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高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2025
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IF 4.7
Pei-hui Shan,Tai-bai Jiang,Hang Zhao,Xiao-yan Wu,Carl Redshaw,Zhu Tao,Xin Xiao
The interaction between 1-(2-hydroxyphenyl)piperazine (HPP) and cucurbit[6]uril (Q[6]) has been explored via 1 H NMR spectroscopy and X-ray crystallography. The results show that the guest molecule 1-(2-Hydroxyphenyl)piperazine hydrochloride is not encapsulated within the Q[6] cavity in both aqueous solution and the solid state. Instead, it resides at the portal of Q[6], forming a highly stable exclusion complex, designated HPP 2 @Q[6]. Notably, ion-dipole and hydrogen-bonding interactions play key roles in stabilizing this complex.
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高影响因子
Journal of Agriculture and Food Research
·
2025
·
IF 6.2
Ziyang Wang,Qinqin Ouyang,Xiaolin Liang,Hongxia Li,Haiying Guo,Rong Liu
Traditional Chinese medicine polysaccharides (TCMPs) have attracted growing attention due to their multi-target and multi-level therapeutic effects in the treatment of diabetes. In this study, we systematically evaluated the antidiabetic effect of three TCMPs, including Moringa oleifera Lam. polysaccharide (MOP), Morus alba L. polysaccharide (MLP) and Lycium barbarum polysaccharide (LBP) in T2DM mouse model. Among the three, MLP exhibited the most pronounced therapeutic efficacy, markedly alleviating hyperglycemia, insulin resistance, hepatic steatosis, and pathological lesions in the liver, pancreas. Liver metabolomic profiling revealed that MLP significantly modulated key glucose and lipid metabolic pathways, particularly bile acid and glycerolipid metabolism. Furthermore, we found MLP exerted its antidiabetic action through inhibition of the mTORC1 signaling pathway, leading to suppressed lipogenesis and enhanced fatty acid oxidation. Notably, MLP-mediated mTORC1 inhibition activated the PPARα–SIRT1 axis, thereby downregulating FOXO1-driven gluconeogenesis and promoting GLUT4-mediated glucose uptake. These findings suggest that MLP exerts comprehensive antidiabetic effects by targeting mTORC1-mediated metabolic reprogramming, offering promise as a natural therapeutic agent for T2DM.
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高影响因子
Journal of Cleaner Production
·
2024
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IF 9.7
Zhonghua Niu,Taoshan Xu,Licheng Zhang,Lianmin Ji,Lijuan Li
With the increasing demand for lithium resources, recovery of lithium from solution with high Na/Li ratio is an effective way to meet the growing demand. Salicylate extraction system has been found to be an effective system for Li/Na separation. In this work, the studies of equilibrium, process and mechanism were carried out for the 2-ethylhexyl salicylate (ES) and trialkyl phosphine oxide (TRPO) co-extraction system. The factors affecting lithium extraction such as composition of the organic phase, the conditions of aqueous phase, extraction time and acid-alkali tolerance of the ES extraction system were systematically investigated; According to the equilibrium study, a series of process studies were carried out for lithium recovery from mother solution of lithium carbonate, and the whole process including extraction, elution, stripping and regeneration was designed, and through the process, 99% of lithium was recovered and lithium-rich solution containing 25.85 g/L Li and 0.08 g/L Na was obtained. In the mechanism study, the extraction process was proved as a thermodynamic spontaneous entropy increase process; At the molecular level, the coordination mechanism was first expounded by ultraviolet–visible (UV–Vis) and fluorescence spectrum (Fl), which was further confirmed by 1 H NMR and Fourier transform infrared (FT-IR). The current study points a way to separation of lithium from alkaline solutions, which will support the future supply of lithium in a more economical and sustainable manner.
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高影响因子
RSC Advances
·
2026
·Vol. 16
·期 9
·8166-8177
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IF 6.1
Yifei Meng,Xuan Ou,Zhenghui Liu,Shun Yao,Chuxiao Hu,Qiuchi Yu,Wenjie Xia
Achieving sustainable and cost-effective production and modulating the structure of biosurfactants is increasingly obtaining attention due to carbon neutrality and eco-safety. Nanotechnology-assisted approaches have been emerging as a promising strategy for this purpose. Here, we investigated the effect of metal oxide nanoparticles on the yield and molecular structure of trehalose lipids produced by Rhodococcus erythropolis WJ-2. Sunflower oil was identified as the optimal carbon source against other oils, yielding 12.60 g L−1. Subsequent optimization of four key medium components (sunflower oil, ZnSO4, (NH4)2SO4, and yeast extract) using a Box–Behnken design elevated the baseline yield to 24.75 g L−1. Interestingly, the trehalose lipid yield was further enhanced to 28.12 g L−1 compared to the optimized medium without NPs when supplemented with 0.5 g per L Fe2O3 NPs (≈20 nm). Furthermore, structural diversity analyzed by FTIR and HPLC-MS showed the obvious m/z value shifts of trehalose lipids with NPs comprising longer hydrophobic fatty acid chains and more unsaturated fatty acid derivatives. In the absence of Fe2O3 NPs, the main m/z peaks were detected at m/z 496, 694, 877, and 1044 (relative abundances: 14.19%, 27.08%, 44.18%, 14.55%), corresponding to short-to-medium-chain fatty acid derivatives (e.g., methyl hexanoate, methyl octanoate). In contrast, the dominant peaks shifted to m/z 673, 807, 874, and 1043 (relative abundances: 22.21%, 18.39%, 47.64%, 11.76%) with Fe2O3 NP supplementation. These findings suggest that the unique redox properties and high surface area of Fe2O3 nanoparticles could enhance the yield and modulate the structures to enable the tailored biosynthesis of glycolipids by influencing key-enzyme activity and metabolic flux. This nanoparticle-assisted fermentation strategy offers a promising route for the scalable production of designer biosurfactants for diverse industrial applications.
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PubMed
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2026
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IF 1.5
Guoqiang Song,Tongtong Zhou,Qiulin Hu,Ming Ni,Xiaoqing Feng,Long Tang
The level of phosphodiesterase type 2 (PDE2) in the body is closely associated with human health. From the L6000 natural compound library, the natural coumarin compound coumestrol was identified as possessing PDE2 inhibitory activity. Using computer-aided drug design software, we modified and synthesized coumestrol derivatives and subsequently evaluated their PDE2 inhibitory activity. Among the synthesized compounds, B2-1 exhibited the strongest activity, with an IC₅₀ value of 1.09 ± 0.07 μM, approximately 7 times higher than that of coumestrol. Finally, ADMET prediction of coumestrol and B2-1 found that B2-1’s ability is equal to or better than coumestrol in terms of intestinal absorption, hepatotoxicity, protein binding, and so on.
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高影响因子
Microorganisms
·
2026
·Vol. 14
·期 6
·1220
·
IF 4.7
Chen Yao,Zhi-Cheng Li,Ruo-Hang Li,Peng-Xiang Liu,Hong-Yun Yang,Hang Liu,Bo Ding,Heng Wang,He-Ping Li,Yue-Ying Wang,Sheng-Li Ming,Li-Jun Shi,Meng-Di Wang
The 3,4-dihydropyrimidin-2(1H)-one (DHPM) scaffold possesses diverse biological activities and chemical tunability, allowing structural modifications to modulate antiviral, anticancer, and anti-inflammatory effects. In this study, a series of DHPM derivatives with varied substituents were designed and synthesized, and their structures were characterized by1H NMR,13C NMR and HRMS. Their antiviral activities against pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) were evaluated. In vitro assays revealed that several compounds exhibited significant antiviral effects, with4bf(SI = 243.08 against PRV),4ce(SI = 196.4 against VSV), and4be(SI = 124.2 against PRV; SI = 181.1 against VSV) showing the most potent activity. Further studies demonstrated effective inhibition of viral titers, and Western blot and qRT-PCR analyses confirmed downregulation of viral proteins and related genes. Cytotoxicity tests indicated that4bf,4ce, and4behad CC50values of 270.0, 147.1, and 190.9 μg/mL, respectively, suggesting favorable safety profiles. In vivo experiments showed that4bf, without affecting normal growth, alleviated PRV-induced pulmonary inflammation and tissue damage, and improved survival in mice. Taken together, DHPM-based compounds demonstrate promising potential as candidate antiviral agents, warranting further development.
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