CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Haijun Sun,Baohao Zhang,Lu Lu,Ziyan Chen,Yaqing Huo,Wenqing Li,Bao Zhang,Jian Song
Eutectogel-based soft materials demonstrate great potential for application in the field of wearable devices. However, the development of multifunctional eutectogel materials as versatile sensors for wearable devices with excellent stretchability, self-healing, stability over a wide temperature range, and adhesion remains a challenge. In this study, we construct a novel dual-network (DN) eutectogel comprising a d -gluconic acetal-based supramolecular network and a polymer network in a deep eutectic solvent. The DN eutectogel exhibited excellent comprehensive properties, such as remarkable stretchability (elongation at break over 4300 %, tensile fracture strain of 0.21 MPa), self-recovery and fatigue resistance, rapid self-healing, outstanding stability over a wide range of temperatures (−20–100 ℃), robust adhesion, and good conductivity. Based on these comprehensive properties and thermosensitive capacity, a temperature sensor based on the DN eutectogel was developed with a high sensitivity of 8.1–65.0 % °C −1 . In addition, wearable strain and pressure sensors based on this eutectogel with high sensitivity, wide monitoring range, and excellent stability were fabricated for precise real-time monitoring of human activities. This study paves the way for the design of multifunctional wearable devices in the future.
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CHEMISTRY & BIODIVERSITY
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2022
·Vol. 19
·期 10
·e202200648
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IF 2.745
Xiao-San Li,Mao-Xun Yang,Yu-Hao Luo,He-Hui Zhan,Mei-Fang Chen,Yong-Mei Huang,Li Liu,Xue-Mei Yang
A series of novel D-ring fused or substituted steroidal N-heterocycles were synthesized, and their chemical structures were characterized by spectroscopic analysis. The anticancer activity of these compounds against four human cancer cell lines (MCF-7, H1299, HeLa and HepG2) were evaluated and the structure-activity relationship (SAR) was also investigated. Compound 3c displayed significant inhibitory activity on the four cancer cells with IC 50 values ranging from 3.88 to 10.05 μM. Overall, these studies indicated that construction of N-heterocyclic system with D-ring substituted containing a double bond at C-16 and C-17 or D-ring fused with [17,16-d]azolo[1,5-a]pyrimidine could be a promising strategy to improve antitumor activity for steroids deserved further investigation. Graphical
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PubMed
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Polymer-Plastics Technology and Materials
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2022
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IF 2.439
Wenqiang Wang,Yiming Gong,Qingxia Huang,Liuzemu Li,Airong Xu,Rukuan Liu
Green polyvinyl alcohol/poly(D,L-lactide-co-glycolide) (PVA/PLGA) composite materials were developed by dissolving PVA and PLGA in hexafluoroisopropanol (HFIP), followed by the subsequent layout of PVA/PLGA/HFIP liquid film and the removal of HFIP. Interestingly, the PVA/PLGA composite materials display remarkedly enhanced tensile strength, elongation at break, biodegradability and biocompatibility. Systematic investigations have been completed to reveal the effects of PVA/PLGA mass ratio on the tensile strength, elongation at break, biodegradability and biocompatibility. Meanwhile, the morphology, crystallinity and chemical structure of the PVA/PLGA material and possible interaction between PVA and PLGA are also investigated using scanning electron micrograph, infrared spectra and X-ray diffraction techniques.
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FOOD CHEMISTRY
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2022
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IF 9.231
Dongbo Wang,Ying Wang,Yuan Li,Ting Shi,Dandan Han,Junbo Gong
Impurity sugars produced in upstream process of functional sugars are significantly impacting the product quality. In this work, the effect of congeners ( d -maltose ( d -MAL), d -fructose ( d -FRU), d -glucose ( d -GLU)) on primary and secondary nucleation of d -tagatose ( d -TAG) crystals was investigated. The impurity sugars showed an inhibition on primary nucleation of d -TAG crystals, while a promotion on the secondary nucleation of d -TAG. Interestingly, the impact of impurity sugars on d -TAG crystal growth was similar to that on primary nucleation. The diffusion ability, hydrogen bonding forming ability, interaction energy of d -TAG crystal surfaces and impurity sugars were evaluated by molecular dynamics (MD) simulations to reveal the nucleation and growth behavior. Based on the above findings, we designed the d -TAG crystallization experiments, and obtained d -TAG crystals with uniform particle size distribution and regular morphology. This study helps to understand the influence of impurity sugars on crystallization, guiding the industrial manufacturing of functional sugars.
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PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
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2022
·Vol. 46
·期 21
·10062-10066
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IF 3.925
Yongrui He,Bing Zheng,Meiling Qi,Lijun Huo
This work reports the separation performance of a new π-conjugated copolymer (PBDB-T) with alternating electron-donor and electron-acceptor units as the stationary phase for capillary gas chromatography (GC). To date, they have not been explored in the field of chromatography. The PBDB-T column exhibited a column efficiency of 3850 plates m−1 determined by n-dodecane at 120 °C and high-resolution performance toward a wide range of aromatic isomers, particularly halobenzenes, phenols, anthracene and phenanthrene. Moreover, it showed excellent separation repeatability and reproducibility in terms of run-to-run, day-to-day and column-to-column and good thermal stability. This work demonstrates the good potential of the indicated D–A copolymer as a new class of stationary phase for chromatographic analyses.
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NEW JOURNAL OF CHEMISTRY
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2022
·Vol. 46
·期 17
·8029-8036
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IF 3.925
Qingju Liu,Saixue Tang,Hui Wang,Ping Han
The current luminescent metal–organic framework (MOF) based fluorescence detection mostly focuses on achiral molecules. The stereospecific recognition and determination of MOF-based detection remain challenging. A novel luminescent terbium-based MOF (Tb-MOF) based biosensing system with excellent performance for stereoselective detection of D-amino acids (D-AAs) was introduced in this paper. D-Amino acid oxidase catalyzes stereospecific oxidative deamination of D-AAs, producing H2O2. The generated H2O2 effectively quenches the fluorescence of Tb-MOF. Under optimum conditions, the D-AAs were detected with excellent efficiency. The linear working range was 0.5–100 μM for D-Alanine (D-Ala) and 0. 5–5 μM for D-Proline (D-Pro), respectively. The limit of detection (Ksv detection) for D-Ala and D-Pro was 0.09 μM and 0.14 μM, respectively. The detection can be performed within 30 min with high selectivity and long-term stability. The fluorescent sensing platform required simple fabrication and operation and was free from complicated reaction processes and expensive reagents. The present sensing system was successfully applied in D-AA detection in human serum with good recovery, indicating its potential application in detection in biological samples.
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Journal of Inorganic and Organometallic Polymers and Materials
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2022
·Vol. 32
·期 2
·572-582
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IF 3.518
Liu Tingting,Zhou Zhiping,Zhang Liming,Zhang Wenwen,Yang Wenming
In this study, we introduced molecular imprinting combined with electrochemical method to determine trace 2,4-dichlorophenoxyacetic acid (2,4-D) herbicide in standard solution and actual samples. For this purpose, we synthesis of vinyl silica coated MWCNTs in alkaline environment with surfactant, molecularly imprinted polymers were prepared on the surface of MWCNTs by free radical polymerization, following the composite materials were dissolved in chitosan solution and dropped on the glassy carbon electrode. The functionalized materials were characterized by fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, thermogravimetry and nitrogen adsorption desorption. Electrochemical performance of molecularly imprinted membrane was characterized by cyclic voltammetry, electrochemical impedance spectroscopy and differential pulse voltammetry. Selectivity, stability and reproducibility of the sensors were also studied and discussed. A good linear relationship for supervising 2,4-D from 1.0 × 10 −4 to 1.0 × 10 −8 mol L −1 with the correlation coefficient of 0.994 and a low LOD of 4.270 nmol L −1 (S/N = 3). The electrochemical sensor has been successfully applied to detect 2,4-D with a recovery rate ranges from 96.2 to 102.4% and a relative standard deviation of less than 4.74%. This work provides potential ideas for detection of trace 2,4-D in real samples.
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ACS Applied Materials & Interfaces
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2023
·
IF 9.5
Xiaohui Niu,Simeng Yan,Rui Zhao,Hongxia Li,Xiaoyu Liu,Kunjie Wang
In the pursuit of chiral materials with significant chiral recognition effects and stability, various strategies have been explored, among which the integration of metal nanoparticles and chiral metal–organic frameworks (CMOFs) is highly promising. However, metal nanoparticles (MNPs)/CMOFs show high chiral properties but inferior stabilities due to the MNPs being easily detached from the outside layer under certain conditions. Sandwich MOFs@MNPs@CMOF chiral materials can overcome this dilemma because the sandwich structure can maximize the regulation of the chiral interface activity, while the controlled outer layer can stop the MNPs from falling off in the procedure of chiral recognition. Here, a novel sandwich chiral material (d-His-ZIF-8@Au@ZIF-8) was synthesized by a ligand-assisted strategy with a well-defined sandwich morphology and chiral recognition capabilities. The electrochemical chiral recognition showed that d-His-ZIF-8@Au@ZIF-8 was the most efficient for the enantiomer of phenylalanine (Phe). This experiment presents a novel perspective for the fabrication of a chiral electrochemical sensing platform based on a solid sandwich chiral nanocomposite.
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MOLECULAR NUTRITION & FOOD RESEARCH
·
2021
·Vol. 66
·期 4
·2101002
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IF 5.82
Cui-Cui Sun,Zhong-Ping Yin,Ji-Guang Chen,Wen-Jun Wang,Guo-Dong Zheng,Jing-En Li,Ling-Li Chen,Qing-Feng Zhang
Scope Alzheimer's disease (AD) is a neurodegenerative disease with phenomena of cognitive impairments. Oxidative stress and cholinergic system dysfunction are two widely studied pathogenesis of AD. Dihydromyricetin (DMY) is a natural dihydroflavonol with many bioactivities. In this study, it is aimed to investigate the effects of DMY on cognitive impairment in d -galactose ( d -gal) induced aging mice. Methods and Results Mice are intraperitoneally injected with d -gal for 16 weeks, and DMY is supplemented in drinking water. The results show that DMY significantly improves d -gal-induced cognitive impairments in novel object recognition and Y-maze studies. H&E and TUNEL staining show that DMY could improve histopathological changes and cell apoptosis in mice brain. DMY effectively induces the activities of catalase, superoxide dismutase and glutathione peroxidase, and reduces malondialdehyde level in mice brain and liver. Furthermore, DMY reduces cholinergic injury by inhibiting the activity of Acetylcholinesterase (AChE) in mice brain. In vitro studies show that DMY is a non-competitive inhibitor of AChE with IC50 value of 161.2 µg mL −1 . Conclusion DMY alleviates the cognitive impairments in d -gal-induced aging mice partly through regulating oxidative stress and inhibition of acetylcholinesterase.
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Biomass Conversion and Biorefinery
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2023
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IF 4
Gao Xin,Xu Tingting,Shi Yunlin,Bai Zhongzhong,Zhou Jun,Wu Hongli,Cao Fei,Wei Ping
Roots and stems comprise a large proportion of traditional Chinese medicines and often serve as the energy storage units of plants. However, their decoction residues still contain a significant amount of starch, and direct landfilling, incineration, or carbon disposal results in a wastage of resources. In this study, five types of starch-rich traditional Chinese medicine decoction residues (TCMDRs)c, namely, Radix Isatidis Rhizoma Dioscoreae , Rhizoma Corydalis and Fritillaria Thunbergii . Radix Paeoniae Alba were screened and hydrolyzed using amylase-glucoamylase to produce fermentable sugar. The resulting glucose yields were 87.54%, 84.51%, 85.14%, 82.55%, and 87.75%, respectively. The enzymatic hydrolysate, after flocculation-decolorization treatment, was used to produce D-lactic acid and ethanol, resulting in a concentration and yield of 121.11 g/L (0.97 g/g) and 54.17 g/L (0.49 g/g), respectively. When single or mixed starch-rich TCMDRs were directly used as feedstocks for ethanol production via simultaneous saccharification and fermentation (SSF), they exhibited similar ethanol fermentability, with yields ranging from 0.33 to 0.43 g/g. The SSF residues were thermochemically transformed into biochar with a specific surface area of 89–459 m 2 /g to reduce secondary waste generation. The utilization value of starch-rich TCMDRs was significantly improved through the implementation of enzymatic hydrolysis to produce fermentable sugars, anaerobic fermentation to produce D-lactic acid and ethanol, and the utilization of fermentation residues for biochar production. Graphical abstract
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DYES AND PIGMENTS
·
2023
·
IF 4.5
Yonghe Zhang,Ruonan Zhou,Jie Sun,Peixuan Li,Deyi Wu,Chunyan Yang,Peng Zhang,Zhenghua Ju
A donor-acceptor (D-A) phenothiazine derivative(PZQ) was designed and synthesized. The PZQ was characterized utilizing infrared (FTIR) and 1 H/ 13 C nuclear magnetic resonance. The fluorescence spectra of PZQ were investigated in various solvents with differing polarities to demonstrate the presence of positive solvatochromism was attributed to the intramolecular charge transfer. It was observed that the Stokes’ shifts increased proportionally with the polarity of the solvents, exhibiting a maximum value of 11420 cm −1 in the highly polar solvent (ACN). Moreover, a porous composite (PZQ@ZIF-8) was fabricated by encapsulating PZQ into the metal-organic framework (ZIF-8) to respond to the organic solvent vapors. The PZQ@ZIF-8 was characterized using infrared, X-ray diffraction (XRD). The fluorescence spectra of the PZQ@ZIF-8 displayed significant solvent-dependent emission. Most importantly, the PZQ@ZIF-8 exhibited high reusability, and a specific response to methanol vapor. The emission intensity of the PZQ@ZIF-8 was correlated with methanol vapor concentration negatively, which was essential for the practical sensing application.
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Cai-Fang Liu,Xiao-Yan Ran,Cheng Liu,Yu-lan Zhu,Yan-Rui Lu,Yu-Ping Yang,Bang-Jin Wang,Jun-Hui Zhang,Sheng-Ming Xie,Li-Ming Yuan:
Chiral metal–organic frameworks, an emerging type of chiral porous materials, possess many outstanding characteristics such as high surface area, tunable pore sizes, and good chemical stability. Herein, we prepared a chiral [Zn 2 (D-Cam) 2 (4,4′-bpy)] n @SiO 2 core–shell composite on the SiO 2 -NH 2 microspheres by an in-situ growth method. The prepared [Zn 2 (D-Cam) 2 (4,4′-bpy)] n @SiO 2 -packed column exhibited high-resolution separation of racemic compounds and positional isomers at a low column backpressure (9–12 bar). Twelve pairs of enantiomers including alcohols, amines, epoxides, ketones, and esters were well resolved with sharp peak shapes on the [Zn 2 (D-Cam) 2 (4,4́-bpy)] n @SiO 2 chromatographic column. Compared the separation performance of [Zn 2 (D-Cam) 2 (4,4́-bpy)] n @SiO 2 -packed column and two chromatographic columns (commercial Chiralpak AD-H column and as-prepared SiO 2 -NH 2 column), the [Zn 2 (D-Cam) 2 (4,4′-bpy)] n -packed column and the commercial Chiralpak AD-H column have a good complementarity in chiral separation, and it also offered better separation performance compared to the SiO 2 -NH 2 column for separating positional isomers. The effects of column temperature and analyte mass on the HPLC separation were investigated. Additionally, the [Zn 2 (D-Cam) 2 (4,4́-bpy)] n @SiO 2 packed column has good repeatability and stability for HPLC separation of enantiomers and positional isomers. The relatvive standard deviations (RSDs) for repeated separations of 2,2,2-trifluoro-1-(9-anthryl)ethanol and o , m , p -bromoaniline were less than 0.8 % and 1.2 % for the retention time and peak area, respectively. After continuous use for one month, the RSDs for the retention time and peak area of them were in the range of 1.1–1.3 % and 1.5–1.8 % (inter-day and intra-day, n = 5), respectively. This work also indicates that the chiral MOFs@SiO 2 composites are promising for HPLC separation.
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