Nano-Micro Letters
·
2025
·Vol. 17
·期 1
·1-14
·
IF 36.3
Zhong Yihong,Yuan Guotao,Bao Dequan,Tao Yi,Gao Zhenqiu,Zhao Wei,Li Shuo,Yang Yuting,Zhang Pingping,Zhang Hao,Sun Xuhui
The heteroatom atomically doping strategy was reported to construct highly
efficient sites on metal oxides for the detection of low-concentration gas.
The atomically dispersed Sn atoms were intentionally incorporated into the Fe 2 O 3
lattice during the oxidative annealing of Fe-based metal organic framework,
leading to specific Sn–O–Fe sites, porous structures, and abundant oxygen
vacancies.
The optimized Sn-Fe 2 O 3 exhibited exceptional sensing performance for NO 2
detection: ultra-high sensitivity ( Rg / Ra =2646.6 to 1 ppm NO 2 ), ultra-low limit of
detection (10 ppb), and high selectivity.
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PLoS One
·
2025
·Vol. 20
·期 5
·e0322056
·
IF 2.6
Wenyue Hou,Ting Zou,Yichao Yan,Yaolong Zhuang,Shaomei Gao,Huijun Ju,Fei Yao,Qin Yuan,Liang Zhou,Guoqiang Liang,Xiudao Song,Lurong Zhang
5-O-Methylvisammioside (5OMV), a flavonol compound derived from the traditional Chinese medicine plant Saposhnikovia divaricat , has been shown to inhibit vasospasm induced by High Mobility Group Box 1 (HMGB1) protein. However, its therapeutic potential and molecular mechanisms in HMGB1-induced tumor angiogenesis remain unexplored. Through comprehensive in vitro assays, we demonstrated that 5OMV significantly attenuates HMGB1-induced proliferation, migration, tube formation, and angiogenic activity in human umbilical vein endothelial cells (HUVECs). Parallel in vivo studies using an orthotopic hepatocellular carcinoma model in C57BL/6 mice revealed that 5OMV treatment markedly reduced tumor progression and microvascular density. Mechanistic studies identified that 5OMV downregulates both total and phosphorylated forms of RAGE, MEK, and ERK in HUVECs and tumor tissues. These findings collectively establish that 5OMV exerts anti-tumor effects in hepatocellular carcinoma through targeted modulation of the HMGB1/RAGE/MEK/ERK signaling axis.
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FOOD CHEMISTRY
·
2020
·
IF 6.306
Yuting Li,Haiping Qi,Meiqi Fan,Zixing Zhu,Shijie Zhan,Lin Li,Bing Li,Xia Zhang,Xianglong Zhao,Jingjing Ma,Lifeng Wang
The reaction efficiency of o -benzoquinones with amines (L-lysine, Nα-acetyl-L-lysine, glycine, L-methionine and L-arginine), thiols (L-cysteine and Nα-acetyl-L-cysteine) and protein (bovine serum albumin) were determined at pH 5.0, 7.0 and 8.0 and scan rate of 10, 50 and 100 mV/s by cyclic voltammetry. Nucleophiles containing multiple nucleophilic groups and nucleophilic group possessing low pKa value would enhance the reactivity of nucleophiles towards o -benzoquinones. The reactivity of different o -benzoquinones with L-lysine/L-cysteine followed the order: protocatechuic acid quinone ≈ catechol quinone > 4-methylbenzoquinone ≈ caffeic acid quinone > rosmarinic acid quinone > chlorogenic acid quinone. The reactivity of quinones would be decreased by the steric hindrance of substituents on quinone ring, and it would also be weakened by enhancing electron cloud density of quinone ring. Adducts generated by the interaction of 4-methylbenzoquinone with amines and thiols were tentatively identified as amine-quinone adduct and thiol-phenol adduct respectively by UPLC-QTOF-MS/MS and cyclic voltammetry.
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Journal of Inorganic and Organometallic Polymers and Materials
·
2025
·
IF 4.9
Wang Chiyuan,Long Xin,Shao Changwei,Huang Jiawei,Ren Jiaqi
Si–B–N–O ceramics are promising materials for wave-transparent windows of hypersonic vehicles due to the excellent thermal stability and low dielectric constant. The polymer-derived ceramics (PDC) route is widely adopted for flexible compositional control of the Si–B–N–O covalent ceramics. In this study, a novel borazine-modified polysilazoxane (RBOSZ) was synthesized using trichlorosilane, tert -butanol, trichloroborazine, and ammonia as starting materials. RBOSZ features a Si–N–Si backbone and borazine rings. The Si–B–N–O ceramic was derived from RBOSZ with a ceramic yield of 61 wt% after pyrolysis under nitrogen atmosphere. Boron facilitates the formation of Si 2 N 2 O nanograins at elevated temperatures and enhances the ceramic’s high-temperature stability. By switching nitrogen to ammonia during organic-inorganic transformation, a low-carbon Si–B–N–O ceramic was obtained and retained its amorphous structure up to 1400 °C. After annealing at 1600 °C, Si 2 N 2 O/β-Si 3 N 4 nanocrystals participated in the Si–B–N–O matrix. This work establishes a facile precursor for high-performance Si–B–N–O ceramics to meet the application demands of heat-resistant wave-transparent windows.
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2025
·
IF 6.2
Weijia Guo,Yutian Lu,Chongyang Zhang,Zhenxing Yue
Low-loss (high- Q × f , where Q = 1/tan δ ) dielectric ceramics can help achieve efficient microwave signal transmission and reduce heat generation. In the traditional Ca-Ln-Ti-O perovskite system (where Ln = rare earth) with the general formula of Ca 1– x Ln 2 x /3 TiO 3 (CST x ), the sharp decline in the Q × f value when x > 0.5 remains unexplained, posing a challenge for designing low-loss ceramics. In this study, CST x ceramics ( x ≤ 0.7) are synthesized via the solid-state reaction method, with a focus on their structure, defects, and broadband dielectric properties. A significant discrepancy between the Q × f values in the microwave and terahertz bands is found when x ≥ 0.6, suggesting the presence of additional loss mechanisms in the microwave band beyond ion displacement depolarization. Meanwhile, the low-frequency dielectric spectra show a weak dielectric relaxation in the low-temperature region, attributed to the partially ordered A -site vacancies. Therefore, this relaxation can act on the microwave frequency band at room temperature, resulting in a sharp decline in Q × f values. Such low-frequency and low-temperature dielectric relaxation should not be ignored in the research of microwave dielectric ceramics. These findings provide a crucial theoretical reference for developing low-loss microwave dielectric ceramics.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2025
·
IF 14.3
Hongxiang Chen,Zhilong Zhang,Xiaochun Wen,Ze Zhang,Fa Chang,Jianeng Huang,Yunfeng Su,Hengzhong Fan,Bing Xiao,Yongsheng Zhang
The discovery of out-of-plane ordered (o-MAX) phases has been largely confined to Al-containing systems, leaving a critical gap in understanding chemical ordering mechanisms across other A-element families. Meanwhile, the 413-type Ge-based MAX phases in bulk form are still lacking. Here, we report the first synthesis of bulk Ge-based 413-type MAX phases: Cr 2 Ti 2 GeC 3 , (Cr 1/3 Ti 1/3 Mo 1/3 ) 4 GeC 3 , and (CrTiVMo)GeC 3 , thereby expanding both structural complexity and chemical ordering paradigms in nanolaminate ceramics, and introducing the second series of o-MAX phases. Through combined Rietveld refinement and atomic-resolution elemental mapping, we demonstrate robust Ti-Cr out-of-plane chemical ordering in these phases, with Ti preferentially occupying the inner metal layers adjacent to Ge atoms and Cr populating the outer layers. This chemical ordering pattern is preserved even in quaternary metal compositions. In contrast, the introduced Mo and V are distributed almost randomly at both sites. First-principles calculations demonstrated the thermodynamic stability and electronic structure, and quantified the mechanical properties of Ge-based 413 phases, revealing enhanced mechanical moduli and tunable ductility through V/Mo incorporation. This work expands the o-MAX family beyond Al-based systems, establishing Ge-containing high- n phases as a platform for designing chemically ordered nanolaminates with tailored stiffness-ductility balance.
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WATER RESEARCH
·
2025
·
IF 12.4
Lingyu He,Xin Zhang,Yang Lei
This study proposes a hybrid electrochemical oxidation-coagulation (EOC) system that integrates a Ti₄O₇ anode with a cathode fabricated from waste aluminum cans, enabling the simultaneous degradation of phosphonates and removal of hardness ions from cooling water. Compared to standalone electrooxidation (EO) and conventional chemical coagulation (CC), the EOC system achieved 41.9% Ca²⁺ removal, 91% total soluble phosphorus (TSP) elimination, and 67.2% conversion of phosphonate to phosphate within 2 hours. Mechanistic studies revealed that the hybrid EOC system performs a synergistic effect, including anodic oxidation of antiscalant (nitrilotris methylene phosphonic acid, NTMP), and the cathodic dissolution of aluminum, generating coagulants that facilitate the concurrent removal of hardness ions and residual phosphorus. The presence of chloride ions enhanced NTMP degradation via the generation of reactive chlorine species (RCS) without impacting Ca²⁺ removal efficiency, whereas the presence of magnesium ions promoted Ca²⁺ removal via Mg(OH)₂ formation, which provides nucleation sites for co-precipitation. On top of mechanical insights, practical validation with real cooling water confirmed the practical effectiveness and robustness of the EOC system. Moreover, energy consumption analysis revealed that the EOC system significantly reduced energy demand for calcium and TSP removal by 91% and 76%, respectively, compared to the EO system. Overall, this work underscores an efficient and cost-effective electrochemical approach for industrial cooling water treatment, establishing foundational insights for scalable implementation.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Ying Yu,Gengwei Lin,Huilin Dai,Qingsong Li,Chao Huang,Yunbo Song
Caffeine (CAF), a compound with stimulant and antimicrobial properties, exhibits widespread environmental distribution due to incomplete wastewater treatment. To address this issue, this study systematically evaluated the removal efficiency and mechanisms of CAF using a vacuum ultraviolet/peracetic acid/MnFe₂O₄ (VUV/PAA/MnFe₂O₄) system. The magnetic MnFe₂O₄ catalyst, synthesized via a hydrothermal method, enabled near-complete CAF removal (>99 % within 20 min) in VUV/PAA/MnFe₂O₄ system under neutral conditions (PAA: 2.0 mM; MnFe₂O₄: 0.25 g∙L −1 ). The assessment of water quality effects indicated that humic acid (HA), CO₃²⁻, Cl⁻, and SO 4 ²⁻ inhibited CAF degradation, while NO₃⁻ demonstrated a slight concentration-dependent influence. Mechanistic studies identified hydroxyl radical (•OH) as the primary reactive species (95 % contribution), with secondary roles played by organic radical (R-C•) and direct VUV photolysis. The sustained •OH generation was facilitated by oxygen vacancies (V O ) and cyclic redox conversion of Mn²⁺/Mn³ ⁺ and Fe²⁺/Fe³ ⁺ on the MnFe₂O₄ surface under VUV irradiation. The system exhibited excellent regenerability, maintaining high removal efficiencies over five consecutive cycles. Importantly, toxicity assessment revealed that the degradation process preferentially transformed CAF into less toxic end products, demonstrating the inherent ecological safety of the system. This study provides insights for designing efficient catalytic systems for CAF-contaminated wastewater treatment.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qiaolan Shi,Lu Yuan,Joop de Vries,Brandon W. Peterson,Jian Liu,Yijin Ren,Henny C. van der Mei
Due to the high resistance and complexity of biofilms, alternatives to traditional antibiotic treatments are urgently needed. Here, we investigated whether Pt nanoparticles grown on Bi 3 O 4 Br nanosheets (Pt NP /Bi 3 O 4 Br) can enhance the efficacy of the antibiotic ampicillin against biofilm-associated infections. X-ray photoelectron spectroscopy revealed abundant oxygen vacancies in the Bi 3 O 4 Br nanosheet creating an ideal surface for Pt nanoparticles growth. The obtained Pt NP /Bi 3 O 4 Br nanozyme had a uniform Pt nanoparticle distribution confirmed by X-ray powder diffraction and transmission electron microscopy with high-angle annular dark-field scanning. Compared to Bi 3 O 4 Br nanosheets alone, the nanozyme demonstrated significantly higher catalytic activity for reactive oxygen species generation facilitated by efficient electron transfer from Pt nanoparticles. When combined with ampicillin, Pt NP /Bi 3 O 4 Br nanozyme significantly enhanced bactericidal efficacy against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli biofilms in vitro as shown by reduction in biofilm thickness and colony-forming units. In a murine skin infection model, the combination accelerated wound healing following S. aureus infection. Additionally, the combined treatment selectively reduced the pathogen Streptococcus mutans in human ex vivo oral biofilms while preserving the healthy human microbiome indicating potential applications in dental care. In conclusion, this work demonstrates that nanozyme-enhanced antibiotic therapy offers a promising strategy to combat biofilm-associated infections and antibiotic resistance.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Yiting Zhang,Siyu Li,Yu Chen,Lixia Guo,Zhijia Liu,Shengbao Cai
This study developed a plant-based W1/O/W2 double emulsion stabilized by potato protein (PP) to improve probiotic viability during storage and gastrointestinal transit. Emulsion was optimized by adjusting polyglycerol polyricinoleate, internal water phase ratio, and PP concentration, and the impact on structural stability and encapsulation efficiency was evaluated. Increasing PP concentration significantly enhanced emulsion stability. At 1.5 % PP, the system exhibited high viscosity, strong strain resistance, and excellent thermal stability, achieving an encapsulation efficiency of 93.99 ± 0.29 % for Lacticaseibacillus paracasei . After 35 days at 4 °C, the encapsulated probiotics maintained 8.06 log 10 CFU/mL, compared with 4.35 log 10 CFU/mL in the free-cell group. Under simulated gastrointestinal digestion, the survival rate reached 86 %, nearly three times higher than unencapsulated probiotics (27.57 %). These findings demonstrate that potato protein-based double emulsions offer an effective and sustainable approach for enhancing probiotic stability, while promoting the high-value utilization of potato processing by-products in plant-based, food-grade delivery systems.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 36
·期 31
·1-22
·
IF 2.8
Guo Yiting,Hao Jingyi,Wang Tian,Su Shen,Yang Shuangshuang,Wang Xingwei,Yu Qiangliang
To investigate the electromagnetic wave absorption performance of electromagnetic-regulated materials and copolymerized composite aerogels with polymer materials, this study loaded nano-Fe 3 O 4 onto modified CNTs through a hydrothermal reaction. The resulting material was then added to a prepolymer solution of acrylic acid and acrylamide monomers for copolymerization, followed by the preparation of composite aerogels using freeze-drying technology (Fe 3 O 4 -CNTs/P(AA-AM)). The influence of the addition amount of nano-Fe 3 O 4 -loaded modified CNTs on the electromagnetic wave absorption performance of the composite aerogels was systematically studied. Notably, the Fe 3 O 4 -CNTs/P(AA-AM)-5 aerogel exhibited the optimal wave-absorbing performance, achieving a minimum reflection loss of −35.5 dB and an effective absorption bandwidth of 5.04 GHz below −10 dB. This is primarily attributed to the excellent dual electromagnetic loss of Fe 3 O 4 -CNTs and the multiple reflection, polarization, and relaxation processes induced by the three-dimensional conductive network constructed within the aerogel skeleton. The performance relationships revealed in this study are of significant importance for the design and preparation of polymer aerogels with effective electromagnetic wave absorption capabilities.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Long Geng,Yun Zhou,Yaowen Zhang,Lipeng Han,Yuankun Liu,Kesheng Hu,Yun Zhou,Fei Wu,Tonghuan Liu,Junqiang Yang,Keliang Shi,Xiaolin Hou
Uranium-235 enrichment generates highly alkaline effluents rich in fluoride and uranyl species, which pose significant challenges to conventional treatment technologies. Herein, we report a polyamine-amide adsorbent (MF-PAA) obtained by densely grafting amide units and multi-level amine groups onto a fluoride-inert, macroporous MA-DVB scaffold, creating a surface rich in O, N multidentate binding sites. MF-PAA exhibits an exceptional adsorption capacity 1.43 × 10 3 mg·g −1 for U(VI), and retains 625 mg·g −1 capacity even under 8000 ppm F − . Even in 0.50 mol·L −1 competing anions, the material removes 80–90% of U(VI) and achieves a distribution coefficient of 5.0 × 10 5 mL·g −1 under cationic competition conditions, confirming outstanding anion tolerance and selectivity. Mechanistic studies combining spectroscopy and density functional theory (DFT) calculations reveal the most stable uranyl-MF-PAA complex (ΔG = −115.66 kJ/mol), in which uranyl coordinates with O and N atoms of two amide groups in adjacent chains, forming six coordination bonds with mixed ionic-covalent character dominated by U 5f/6d, N 2p, and O 2s/2p orbital interactions. In column operation with a continuous 8000 ppm F − influent, MF-PAA recovered 94% of U(VI), and its capacity maintained after 15 days of high-fluoride exposure, confirming its long-term engineering viability. These results underscore MF-PAA as a robust, renewable, and high-capacity adsorbent with strong potential for uranium recovery from fluoride-rich wastewater.
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