Food Bioscience
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2025
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IF 5.9
Lingling Bai,Yurui Wu,Huijin Xu,Jiyuan Yang,Yiting Lu,Wenge Yang,Yonghong Hu
In this study, K-carrageenan (KC)/poly(lactic acid) (PLA) composite nanofiber membranes loaded with vitamin C (VC)/2-hydroxypropyl-β-cyclodextrin (HP-β-CD) inclusion complexes were prepared by electrostatic spinning for blueberry preservation. A scanning electron microscope, electronic universal testing machine, and other instruments were used to analyze the apparent and mechanical properties of the membrane as well as the physicochemical indexes of blueberries during the preservation process. The loading of the inclusion raised the average diameter of the nanofibers membrane, reduced the crystallinity, and hydrophobicity, and improved the thermal stability of the fibers membrane. The release curves showed that encapsulating the inclusion complex in KC/PLA significantly prolonged the release time of VC. The membranes exhibited better antimicrobial properties as well as higher antioxidant properties in vitro and in vivo . These results indicate that the developed antimicrobial membrane has good application prospects in food packaging.
研究领域:
食品科学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF CATALYSIS
·
2020
·
IF 7.888
Jichang Lu,Jian Fang,Zhizhi Xu,Dedong He,Siyou Feng,Yubei Li,Gengping Wan,Sufang He,Hua Wu,Yongming Luo
Supported MoS 2 based materials are widely used as heterogeneous catalysts. In this work, we propose a rapid and facile method (ultrasound-induced impregnation assisted by microwave thermal treatment) to synthesize mesoporous silica (SBA-15)-supported, few-layer, ordered and K-promoted MoS 2 nanosheets with different K/Mo ratios. The prepared catalysts are characterized by various physical and chemical techniques. Their catalytic performance is evaluated by methyl mercaptan (CH 3 SH) synthesis from CO/H 2 /H 2 S. The results show that our catalysts exhibit a much higher CO conversion and selectivity to CH 3 SH than the catalysts prepared using the conventional impregnation and reported in the literature. The good performance arises because of two main factors: MoS 2 nanosheets of only 2–4 layers and K promotion. Experimental characterizations and (density functional theory) calculations show that the former is the typical nano-size effect, and the latter stabilizes C S bonds when activating COS molecules.
研究领域:
催化材料
·
物理化学
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产品关联
DOI
高影响因子
Materials Today Communications
·
2025
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IF 4.5
Jiwei Yao,Weijun Ren,Qing Guo,Ziqi Guan,Dongliang Zhao,Jun He,Bing Li
The development of ultra-low-temperature magnetocaloric materials (MCMs) is crucial for advanced cryogenic refrigeration technologies. Rare-earth fluorides exhibit promising magnetocaloric properties, but the high magnetic ordering temperatures ( T 0 ) limit their performance below 2 K. Single-phase KLnF 4 (Ln = Tb, Dy, Ho, Er, Tm) compounds with a trigonal structure were successfully synthesized by introducing the diamagnetic K⁺ ions into LnF 3 via solid-state sintering. Structural analysis confirms that the K⁺ incorporation increases the distance between Ln 3+ ions, suppressing dipolar interactions and reducing T 0 to below 2 K. Notably, KHoF 4 exhibits a 16.5 % higher magnetic entropy change (-∆ S M ) than HoF 3 , attributed to the lower magnetic anisotropy of the trigonal KHoF 4 with higher symmetry. The effects of these two aspects overcome the negative impact caused by the decrease of the magnetic ion concentration. These findings demonstrate that K⁺ incorporation is a dual-functional strategy for simultaneously modulating transition temperatures and magnetocaloric performance of rare-earth fluorides. This work provides a scalable approach to designing ultra-low-temperature MCMs with various refrigeration windows.
研究领域:
材料科学
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凝聚态物理
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低温工程
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磁性材料
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产品关联
DOI
高影响因子
APPLIED GEOCHEMISTRY
·
2017
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IF 2.581
Wei Zhang,Li Zhou,Hongfeng Tang,Heping Li,Wenlei Song,Gang Xie
The solubility of fluorite in hydrothermal conditions is important in ore forming and geothermal processes and groundwater utilization. However, a quantitative description of the geochemical behavior of fluorite under hydrothermal conditions has not been previously reported. In this work, the solubility of fluorite in Na-K-Cl solutions at temperatures up to 260 °C and ionic strengths up to 4 M was determined by experiments and modeling. The solubility products obtained in this work at 30 and 50 °C under ambient pressure and those from literature were used to regress the density model parameters for fluorite solubility product calculation at high temperature. The Pitzer interaction model was adopted to calculate the activity coefficient . The fluorite solubility determined in KCl solution at 250 °C under vapor saturated pressure and that from the literature were combined with the low-temperature thermodynamic properties of heat capacity and osmotic coefficient to obtain the binary parameters of NaF and KF at temperatures up to 260 °C. A thermodynamic model was then developed for calculating the fluorite solubility in Na-K-Cl solution at temperatures up to 260 °C, under vapor saturated pressure and ionic strengths up to 4 M. As calculated from this model, fluorite solubility measured at 200 °C and 0.1 M NaCl was well predicted. Both temperature and ionic strength had significant effects on fluorite solubility, and fluorite exhibited a similar dissolution pattern in both NaCl and KCl solution. When the concentration was lower than 2 M, the solubility of fluorite first increased with temperature, reached a maximum at approximately 100 °C, and then decreased. When the concentration was higher than 2 M, the solubility of fluorite increased monotonically with temperature.
研究领域:
地球化学
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热液地质学
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DOI
高影响因子
FEBS Journal
·
2018
·Vol. 285
·期 12
·2292-2305
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IF 4.53
Jin-Hua Guo,Ren-Wang Jiang,Jacob Lauwring Andersen,Mikael Esmann,Natalya U. Fedosova
The information obtained from crystallized complexes of the Na + ,K + -ATPase with cardiotonic steroids (CTS) is not sufficient to explain differences in the inhibitory properties of CTS such as stereoselectivity of CTS binding or effect of glycosylation on the preference to enzyme isoforms. The uncertainty is related to the spatial organization of the hydrophilic cavity at the entrance of the CTS-binding site. Therefore, there is a need to supplement the crystallographic description with data obtained in aqueous solution, where molecules have significant degree of flexibility. This work addresses the applicability of the electron paramagnetic resonance (EPR) method for the purpose. We have designed and synthesized spin-labeled compounds based on the cinobufagin steroid core. The length of the spacer arms between the steroid core and the nitroxide group determines the position of the reporting group (N-O) confined to the binding site. High affinity to Na + ,K + -ATPase is inferred from their ability to inhibit enzymatic activity. The differences between the EPR spectra in the absence and presence of high ouabain concentrations identify the signature peaks originating from the fraction of the spin labels bound within the ouabain site. The degree of perturbations of the EPR spectra depends on the length of the spacer arm. Docking of the compounds into the CTS site suggests which elements of the protein structure might be responsible for interference with the spin label (e.g., steric clashes or immobilization). Thus, the method is suitable for gathering information on the cavity leading to the CTS-binding site in Na + ,K + -ATPase in all conformations with high affinity to CTS .
研究领域:
生物化学
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药理学
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DOI
高影响因子
International Journal of Electrochemical Science
·
2023
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IF 1.5
Shaohua Luo,Yuxia Liu
Poly(acid chrome blue K) modified glassy carbon electrode (GCE) was electropolymerized by cyclic voltammetric sweep in the potential range from –0.2 to 0.9 V. The characteristic of Poly(acid chrome blue K) film was studied by different methods such as electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. This modified electrode showed excellent electrocatalytic response to vanillin with the increase of the electrochemical responses. Under the optimal conditions a good linear voltammetric response could be obtained over the range of 1.0×10 -7 ~ 7.0×10 -5 mol dm -3 and the detection limit was got as 3.2×10 -8 mol dm -3 (3σ). The proposed method was successfully applied to biscuits and dark-chocolate samples with satisfactory results.
研究领域:
分析化学
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电化学
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食品分析
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传感器
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分子检测
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DOI
高影响因子
Advanced Science
·
2023
·Vol. 10
·期 13
·2207329
·
IF 15.1
Zhi-Qiang Wang,Hong-Ming Chen,Xiao-Dong Liu,Li-Ying Song,Bu-Sheng Zhang,Yun-Guo Yang,Zhao-Cheng Zhang,Qian Li,Tian-Qi Gao,Jing Bai,Woon-Ming Lau,Dan Zhou
Aqueous Zn-ion batteries (AZIBs) and Zn-ion hybrid supercapacitors (AZHSCs) are considered promising energy-storage alternatives to Li-ion batteries due to the attractive merits of low-price and high-safety. However, the lack of suitable cathode materials always hinders their large-scale application. Herein, amorphous K-buserite microspheres (denoted as K-MnO x ) are reported as cathode materials for both AZIBs and AZHSCs, and the energy-storage mechanism is systematically revealed. It is found that K-MnO x is composed of rich amorphous K-buserite units, which can irreversibly be transformed into amorphous Zn-buserite units in the first discharge cycle. Innovatively, the transformed Zn-buserite acts as active materials in the following cycles and is highly active/stable for fast Zn-diffusion and superhigh pseudocapacitance, enabling the achievement of high-efficiency energy storage. In the AZIBs, K-MnO x delivers 306 mAh g −1 after 100 cycles at 0.1 A g −1 with 102% capacity retention, while in the AZHSCs, it shows 515.0/116.0 F g −1 at 0.15/20.0 A g −1 with 92.9% capacitance retention at 5.0 A g −1 after 20 000 cycles. Besides, the power/energy density of AZHSCs device can reach up to 16.94 kW kg −1 (at 20 A g −1 )/206.7 Wh kg −1 (at 0.15 A g −1 ). This work may provide some references for designing next-generation aqueous energy-storage devices with high energy/power density.
研究领域:
材料科学
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电化学
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产品关联
DOI
PubMed
高影响因子
Chinese Medicine
·
2022
·Vol. 17
·期 1
·1-12
·
IF 4.546
Wang Li,Shao Li,Chen Man-Yun,Wang Lin,Zhang Wei,Tan Feng-Bo,Huang Wei-Hua
Background Ginsenoside compound K (GC-K) potentially alleviates ulcerative colitis involved in gut microbiota, which is significantly associated with the occurrence and development of colitis. However, the effect and mechanism of GC-K on anti-colitis in relation to gut microbiota are not clear. This study focused on the prevention and mechanism of GC-K on Dextran sulfate sodium (DSS)-induced colitis of mice pertinent to gut microbiota. Methods DSS was used to establish a chronic colitis mouse model. Body weight analysis, colon length measurement, HE staining, and inflammatory factors levels were processed in animal experiments. Flow cytometry was employed to analyze Th17/Treg cells in the mouse spleen and blood. 16S rRNA sequencing was utilized to analyze gut microbiota. Fecal microbiota transplantation (FMT) experiment was employed to verify the anti-colitis efficacy of GC-K by reshaping gut microbiota. Results GC-K significantly relieved colitis-related symptoms due to decreased disease activity index (DAI) scores, spleen weight, and increased colon length. Additionally, the tight junction proteins were increased, and the pro-inflammatory cytokines, such as TNF-α, IL-6, IL-1β and IL-17, were decreased after GC-K treatment. Furthermore, Bacteroides spp. significantly increased after modeling. Moreover, FMT experiments confirmed that GC-K-driven gut microbiota greatly relieved DSS-induced colitis. Conclusion GC-K alleviated colitis via the modulation of gut microbiota. Graphical Abstract
研究领域:
药理学
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免疫学
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微生物学
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胃肠病学
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产品关联
DOI
PubMed
高影响因子
Advanced Science
·
2023
·Vol. 10
·期 32
·2304067
·
IF 15.1
Lin-Rong Wu,Yu-Han Zhang,Zhen Wu,Jinlv Tian,Haorui Wang,Haijun Zhao,Shoudong Xu,Liang Chen,Xiaochuan Duan,Ding Zhang,Huijuan Guo,Ya You,Zhi Zhu
High-capacity O3-type layered sodium oxides are considered one of the most promising cathode materials for the next generation of Na-ion batteries (NIBs). However, these cathodes usually suffer from low high-rate capacity and poor cycling stability due to structure deformation, native air sensitivity, and interfacial side reactions. Herein, a multi-site substituted strategy is employed to enhance the stability of O3-type NaNi 0.5 Mn 0.5 O 2 . Simulations indicate that the Ti substitution decreases the charge density of Ni ions and improves the antioxidative capability of the material. In addition, the synergistic effect of K + and Ti 4+ significantly reduces the formation energy of Na + vacancy and delivers an ultra-low lattice strain during the repeated Na + extraction/insertion. In situ characterizations verify that the complicated phase transformation is mitigated during the charge/discharge process, resulting in greatly improved structure stability. The co-substituted cathode delivers a high-rate capacity of 97 mAh g −1 at 5 C and excellent capacity retention of 81% after 400 cycles at 0.5 C. The full cell paired with commercial hard carbon anode also exhibits high capacity and long cycling life. This dual-ion substitution strategy will provide a universal approach for the new rational design of high-capacity cathode materials for NIBs.
研究领域:
材料科学
·
电化学
·
电池技术
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DOI
高影响因子
CHEMOSPHERE
·
2019
·
IF 5.108
Nannan He,Shihai Cao,Lihao Zhang,Zhidan Tian,Huan Chen,Fang Jiang
The porous graphitic carbon nitride nanosheets (PCNSs) with high yields were synthesized by using one–step chemical exfoliation method. PCNSs accelerated separation efficiency of photo-generated electron−hole pairs in comparison to bulk graphitic carbon nitride. The PCNS5 (exfoliation for 5 h) exhibited optimal photocatalytic disinfection capability towards Escherichia coli K-12 under simulated solar light irradiation with complete disinfection of 6.5 log 10 cfu/mL of E. coil K-12 within 2 h. The enhanced photocatalytic activity of PCNS5 originated from mesoporous nanosheet structure. The possible mechanism of photocatalytic disinfection has proposed that intracellular reactive oxygen species levels and the activities of antioxidant enzymes (e.g., catalase and superoxide dismutase) were enhanced. Transmission electron microscope images observed during photocatalytic disinfection process suggested that the cell membrane was regarded as the first target for oxidation, resulting in a faster leakage of cytoplasmic content and finally degradation of DNA leading to bacterial death. Furthermore, the trapping experiment showed that superoxide radical (•O 2 − ) and holes (h + ) were responsible for E. coli K-12 disinfection by PCNS5.
研究领域:
微生物学
·
环境科学
·
材料科学
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DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2022
·
IF 3.119
Yanjuan Peng,Ziteng Wang,Wenhao Jiao,Xinxin Cheng,Jingjing Yang,Yonghong Hu,Li Mi
This article deals with the saturated solubility and solvation behavior of 2-bromo-9-fluorenone in 10 industrial common solvents and three binary mixed solvents by means of experimental and mathematical correlations. Solubility experiments were investigated using the static equilibrium method combined with high-performance liquid chromatography (HPLC) from 278.15 to 323.15 K at atmospheric pressure. The results showed that the maximum and minimum solubility of 2-bromo-9-fluorenone was 0.0526 (mole fraction) in 1,4-dioxane at 323.15 K and 0.0002 (mole fraction) in methanol at 278.15 K, respectively, and the solubility increased with the increase in temperature in all solvents. Furthermore, the solubility data of 2-bromo-9-fluorenone was analyzed using the Apelblat model, the Buchowski–Ksiazaczak λh model in pure solvents, CNIBS/R-K model, and the Jouyban–Acree model in binary solvent mixtures. By error comparison, the Apelblat model and the CNIBS/R-K model can better predict the solubility of 2-bromo-9-fluorenone. In addition, the solvation behavior was illustrated by the KAT-LSER model in pure solvents, and the result shows that the cohesive energy density in the solution is the main factor affecting 2-bromo-9-fluorenone. Therefore, the solubility data is very important for optimizing the extraction process and recrystallizing 2-bromo-9-fluorenone to obtain a higher yield in industry production.
研究领域:
化学工程
·
物理化学
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产品关联
DOI
高影响因子
BRITISH JOURNAL OF PHARMACOLOGY
·
2022
·Vol. 179
·期 18
·4563-4574
·
IF 9.473
Rongcai Ye,Chunlong Yan,Huiqiao Zhou,Chuanhai Zhang,Yuanyuan Huang,Meng Dong,Hanlin Zhang,Jun Lin,Xiaoxiao Jiang,Shouli Yuan,Li Chen,Rui Jiang,Ziyu Cheng,Kexin Zheng,Anni Yu,Qiaoli Zhang,Lin-hu Quan,Wanzhu Jin
Background and Purpose Polycystic ovary syndrome (PCOS) is a common metabolic and endocrine disease affecting women of reproductive age. Due to its complex aetiology, there is no currently effective cure for PCOS. Brown adipose tissue (BAT) activity is significantly decreased in PCOS patients, and BAT activation has beneficial effects in animal models of PCOS. Here, we investigated the effect of ginsenoside compound K (CK) in an animal model of PCOS and its mechanism of BAT activation. Experimental Approach Primary brown adipocytes, Db/Db mice and dehydroepiandrosterone (DHEA)-induced PCOS rats were used. The core body temperature, oxygen consumption, energy metabolism related gene and protein expression were assessed to identify the effect of CK on overall energy metabolism. Oestrous cycle, serum sex hormone, ovarian steroidogenic enzyme gene expression and ovarian morphology were also evaluated following CK treatment. Key Results Our results indicated that CK treatment could significantly protect against body weight gain in Db/Db mice via BAT activation. Furthermore, we found that CK treatment could normalize hyperandrogenism, oestrous cyclicity, normalize steroidogenic enzyme expression and decrease the number of cystic follicles in PCOS rats. Interestingly, as a potential endocrine intermediate, C-X-C motif chemokine ligand-14 protein (CXCL14) was significantly up-regulated following CK administration. In addition, exogenous CXC14 supplementation was found to reverse DHEA-induced PCOS in a phenotypically similar manner to CK treatment. Conclusion and Implications In summary, CK treatment significantly activates BAT, increases CXCL14 expression and ameliorates PCOS. These findings suggest that CK might be a potential drug candidate for PCOS treatment.
研究领域:
内分泌学
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代谢学
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药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）