EMBO JOURNAL
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2026
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IF 8.4
Niu Sheng,Tian Yuyang,Nguyen Linh,Bai Chongzhi,Hou Xiaohan,Wang Dan,Niu Ziqian,Liu Zhimin,Ren Jianle,Li Wentao,Wang Qihui,Tian Wen-xia,Sun Junqing,Gao George Fu
Type-II feline infectious peritonitis virus (FIPV-II) is a lethal alphacoronavirus, whose high homology with the human coronavirus CCoV-HuPn-2018 carries the risk of potential zoonotic FIPV-II transmission to humans. FIPV-II infects felids using cat aminopeptidase N (cAPN) as its cell-entry receptor, but the molecular details remain unclear. Here, we resolved cryo-electron microscopy (cryo-EM) structures of the spike (S) trimer of a representative FIPV-II strain 79-1146 (FIPV-1146), and of its complex with cAPN. The reconstructions reveal structural transitions of the S protein between the “standing” and “lying” receptor-binding domain (RBD) conformation upon complex formation with cAPN in its open conformation. Structural and mutational analyses revealed that the cAPN residues R378, D751 and R779, as well as the N748-linked glycan are essential for high-affinity RBD engagement. Cross-species analysis demonstrated narrow tropism of FIPV-1146, limited to felids and canids. Introducing the N595K and Q596R substitutions found in transmissible gastroenteritis virus (TGEV) into the FIPV-1146 RBD expands its binding capacity to APNs from pig, bovine, horse and giant panda. These findings provide insights into the entry mechanism and zoonotic constraints of FIPV-II, with potential relevance for antiviral strategies against coronaviruses.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2026
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IF 3.9
Shucheng Liu,Bo Wang,Ruiheng Lu,Hongxiang Ou,Xuan Zhang
Naringin (NRG) is a bioactive substance with important pharmaceutical and industrial value. However, the major challenges in the separation of NRG arise from the complexity and low concentration of crude extracts. In this work, by integrating the advantages of magnetic separation, MOFs@COFs composite materials, and surface molecular imprinting strategy, a new kind of magnetic MOF@COF-based boronate-affinity molecular imprinted adsorbent (NH2-MIL-68-Fe3O4@COFs@BA-MIPs) was constructed. Magnetic NH2-MIL-68 substrates were prepared by the solvothermal method, aldehyde-functionalized by surface modification with 2,4,6-triformylphloroglucinol (Tp). Then, a covalent organic framework shell was grown on the surface of substrates via the Schiff base reaction. Finally, a boronate-affinity imprinted polymer was prepared via surface-initiated atom transfer radical polymerization (SI-ATRP). The as-prepared adsorbent features rapid magnetic separation. In addition, the high-density boronate-imprinted recognition sites and porous structure endow the material with a fast adsorption rate (reaching equilibrium about 60 min), a high adsorption capacity (57.29 μmol g–1), and good retention performance (92.79%) after six adsorption–desorption cycles at 308 K under pH 8.0. Moreover, the extraction rate of crude NRG by NH2-MIL-68-Fe3O4@COFs@BA-MIPs reached 93.61%. This study provides a design strategy for constructing NRG adsorbents with rapid magnetic response and has important application value in the specific separation and purification of flavonoids.
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POLYMER COMPOSITES
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2026
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IF 4.9
Lin Jiang,Xiansheng Liu,Yunhui Yang,Zhengqiang Huang,Shihua Liu,Zhongwei Zhang,Tie Geng,Maning Liu
Insufficient interfacial compatibility and inherent flammability of polymer matrices are two critical factors that limit the practical application of basalt fiber–reinforced polymer composites (BFRPs). In this study, an interfacial engineering strategy based on the in situ growth of nano-SiO 2 is proposed. DOPO-functionalized linear and cage-like interfacial structures are then constructed on the basalt fiber surface using silane coupling agent (KH560) and polyhedral oligomeric silsesquioxane (POSS), respectively. Our results demonstrate that interfacial modification remarkably strengthened fiber–resin interfacial bonding, leading to significant improvement in tensile and flexural properties. Additionally, the modified composites exhibit substantially increased limiting oxygen index values and both achieve a UL-94 V-0 rating, accompanied by effective suppression of heat release during the combustion. Mechanistic analysis reveals that the enhanced flame retardancy originates from the synergistic action of radical quenching by DOPO in the gas phase as well as the formation of a compact, insulating char layer promoted by silicon-based structures in the condensed phase. Notably, the DOPO-POSS system exhibits more pronounced advantages in interfacial reinforcement and char-layer stability owing to its three-dimensional cage architecture. This work offers an effective interfacial engineering strategy for the design of BFRPs with simultaneously enhanced mechanical performance and fire safety. Highlights Phosphorus-functionalized interfaces enable mechanical–flame synergy. In situ nano-SiO 2 anchoring ensures robust DOPO grafting. DOPO-POSS forms a rigid interfacial structure for improved load transfer. Phosphorus–silicon synergy promotes char formation and suppresses heat release.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124035
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IF 7.5
Li Xue,Yin Wang,Nanya Zhong,Yukun Xue,Li Wu,Kama Huang,Jiesi Luo
Microwave plasma technology, particularly the three-layer coaxial low-temperature atmospheric pressure microwave plasma jet, offers a promising solution for pollutant degradation due to its electrode-free design and low microwave energy consumption. However, a comprehensive evaluation of its performance in antibiotic degradation has been lacking. To tackle this challenge, this study evaluates the effectiveness of this microwave plasma jet in degrading two widely used antibiotics, sulfamethoxazole and oxytetracycline, as well as their combined mixture. The results show that the proposed technology achieves excellent degradation and mineralization efficiencies. The removal rates for the mixed antibiotic solution are 11.13% and 26.28% higher than those for sulfamethoxazole and oxytetracycline individually. In order to optimize the experimental design, explainable artificial intelligence models were developed to predict degradation efficiency and identify key influencing factors. The computational models demonstrated high predictive accuracy, with Pearson correlation coefficients ranging from 0.978 to 0.991 when validated on independent datasets. Furthermore, free radical capture experiments revealed the critical role of hydroxyl radicals in the degradation process. Bio-toxicity assessments confirmed the ecological safety of the microwave plasma treatment. Finally, the analysis of reaction intermediates proposed potential degradation pathways, providing a molecular-level understanding of the degradation process. In conclusion, this study highlights the three-layer coaxial low-temperature atmospheric pressure microwave plasma as a highly effective technology for antibiotic removal and offers valuable insights for its application in wastewater treatment.
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JOURNAL OF POWER SOURCES
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2026
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IF 8.4
Fangyu Meng,Ziheng Liu,Daxin Shi,Yaoyuan Zhang,Kangcheng Chen,Qin Wu,Hansheng Li
Homogeneous and transparent proton exchange membranes (PEMs) denoted as HBPPQ/PPQ-x are fabricated via in situ combination of hyperbranched polyphenylquinoxaline (HBPPQ) and linear polyphenylquinoxaline (PPQ). The rigid hyperbranched structure generates stable nanocavities, giving HBPPQ/PPQ-50 high fractional free volume (FFV) of 37%. Moderate main-chain basicity provides favorable phosphoric acid (PA) affinity, leading to the PA uptake of 334%. HBPPQ/PPQ-x membranes exhibit pronounced anisotropic swelling and proton conduction behavior. HBPPQ/PPQ-50 delivers the σ ⊥ of 76 mS cm −1 at 180 °C, 3.1 times the in-plane conductivity ( σ // ). It shows an open-circuit voltage of 1.004 V, higher than commercial PBI (0.977 V), and maximum power density of 1122 mW cm −2 , twice that of PBI at 180 °C without back pressure. No obvious voltage decay is observed during 200 h durability test at 160 °C and 0.2 A cm −2 . These results demonstrate that constructing high free volume hyperbranched/linear composite membranes is an effective strategy to simultaneously enhance PA uptake, proton conduction, and HT-PEMFC performance.
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Guixia Wang,Yao Lei,Liqiang Yang,Zhuo Yang,Ruting Zheng,Xianming Liu,Min Wang
The phosphatase-like activity of UiO-66 was improved by introducing OMS. • UiO-66-OMS exhibited twice the catalytic activity of pristine UiO-66. • This enhanced activity results from enlarged pores and boosted Lewis acidity. • A sensitive colorimetric immunoassay was developed for the detection of CEA. UiO-66 with open metal sites (UiO-66-OMS) nanozymes were synthesized via defect engineering through the introduction of benzoic acid as a modulator during UiO-66 synthesis. As a monocarboxylic acid analogous to the organic ligand 1,4-benzenedicarboxylic acid (BDC), benzoic acid competes with BDC for coordination to Zr O clusters, thereby creating abundant coordinatively unsaturated open metal sites while preserving the crystal structure of UiO-66. Using 4-nitrophenyl phosphate ( p -NPP) as the model colorimetric substrate, UiO-66-OMS exhibited enhanced phosphatase-like catalytic activity, which was twice that of pristine UiO-66. Mechanistic investigations revealed that the increased activity stems from the enlarged pore size and specific surface area of the nanozyme, as well as its enhanced Lewis acidity. By employing UiO-66-OMS as an antibody label, a sensitive colorimetric immunoassay was developed for the detection of carcinoembryonic antigen (CEA), with a linear range of 10–400 ng/mL and a limit of detection of 1.17 ng/mL. This study offers a new strategy for the development of highly active MOF-based nanozymes. Download: Download high-res image (111KB) Download: Download full-size image
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CERAMICS INTERNATIONAL
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2026
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IF 6
Qiang Liu,Kai Cui,Zihang Liao,Changyi Wu,Longhui He,Shuwei Yao
Electrospun alumina-mullite ceramic nanofibrous membranes show great potential for high-temperature thermal insulation applications. However, the influence of scandium oxide (Sc 2 O 3 ) addition on their phase evolution and high-temperature stability has rarely been investigated. Herein, the concentration-dependent effect of Sc 2 O 3 (0–5 wt.%) on these membranes was systematically studied. Microstructural and crystallization kinetics analyses reveal a non-monotonic doping behavior. A Sc 2 O 3 content of 1 wt.% delays mullitization and retains a fine-grained, flexible nanofiber architecture after calcination at 1400 °C. In contrast, Sc 2 O 3 additions of 3 wt.% and 5 wt.% induce excessive lattice distortion, accelerate mullite crystallization, and promote abnormal grain growth. These findings demonstrate that the Sc 2 O 3 doping concentration determines the transition from grain refinement to coarsening, providing a basis for designing durable ultra-high-temperature ceramic nanofibrous membranes.
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APPLIED SURFACE SCIENCE
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2026
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IF 6.6
Shaofei Song,Pengfei Li,Fulin Zhou,Yang Deng,Xu Wu
TD-COF/NiFe-LDH heterojunction photocatalyst was in situ constructed on floatable carbonized wood. • Efficient degradation of broad-spectrum pollutants is achieved through pollutant enrichment and dual-pathway electron/energy transfer. • Active oxygen species are selectively generated, enabling highly efficient degradation of various antibiotics and dyes. Hierarchical TD-COF/NiFe-LDH heterojunction photocatalytic materials were constructed using natural wood‑derived carbonized wood as a carrier. The anisotropic macroporous channels of the carbonized wood serve as an efficient “water transport system,” and the heterojunction was prepared via an in‑situ growth method. The material achieves a dual synergy between mass transfer and catalysis: the vertically aligned through‑channels of the carbonized wood promote rapid adsorption and enrichment of pollutants, while its three‑dimensional conductive framework provides an efficient electron transport network. Simultaneously, the TD-COF/NiFe-LDH heterojunction interface significantly enhances the separation efficiency of photogenerated charge carriers. Mechanistic studies reveal that under visible light, the material selectively generates singlet oxygen ( 1 O 2 ) and superoxide radicals (•O 2 – ). In this process, TD-COF primarily drives the energy transfer pathway for 1 O 2 , while the heterojunction structure facilitates the efficient reduction of O 2 via electron transfer. The experimental results indicated that a variety of antibiotics and dyes, including ciprofloxacin (CIP), tetracycline (TC), rhodamine B (RhB), and methylene blue (MB), could be efficiently degraded through the synergistic mechanism of the material, which demonstrated excellent catalytic performance. This work provides a new strategy for designing photocatalysts based on natural biomass. Download: Download high-res image (204KB) Download: Download full-size image
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·123941
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IF 7.5
Mengyuan Yang,Yanling Li,Temitope Fausat Ajibade,Ziang Zhou,Zhaoping Cai,Lixiang Li,Huali Tian
Covalent organic frameworks (COFs) are effective materials for water treatment membranes due to their tunable pore structures and high compatibility. While composite modification strategies combining plant polyphenol tannic acid (TA)-Fe³⁺ and COFs show great promise for TFC membranes, they typically involve organic solvents or complex pre-modification of the fillers. In this study, a green, fully-aqueous layer-by-layer (LbL) self-assembly strategy was employed to prepare TA-Fe(COF-LZU1)/PES membranes. By exploiting the inherent synergy between the rigid crystalline channels of COF-LZU1 and the adhesive TA-Fe network, this approach directly utilizes pristine COF-LZU1 without secondary modification. Unlike conventional methods, the entire process avoids organic solvents, offering a highly sustainable technical alternative. The incorporation of COF-LZU1 significantly enhanced the membrane surface properties, with surface roughness increasing from 17.0 ± 2.2 nm to 43.8 ± 8.5 nm and the water contact angle decreasing from 77.0 ± 1.6° to 20.0 ± 1.0°, thereby substantially improving the membrane’s hydrophilicity. The TA-Fe(COF-LZU1)/PES membrane achieved a pure water permeance of 35.85 L·m - ²·h - ¹·bar - ¹, representing a 11.5% increase over the TA-Fe/PES membrane. It exhibited excellent separation performance, achieving high rejections of 98.3% for Direct Red 80, and further demonstrated robust stability in mixed dye/salt solutions. In five-cycle bovine serum albumin (BSA) tests, the membrane exhibited improved antifouling durability, yielding a flux recovery ratio of 75.5%. Additionally, it operated stably across a pH range of 4–8. This green self-assembly approach provides a practical strategy for preparing composite membranes for dye wastewater treatment.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Xinxin Liang,Yongqian Cui,Ning Liu,Qibing Dong,Ximing Li,Ying Wang,Chao Ma,Chuanyi Wang
Sulfur vacancies increase Cd site charge density, favoring end-on O 2 adsorption. • End-on adsorption inhibits O O bond cleavage, suppressing •OH radical formation. • Overoxidation of pyruvic acid is prevented, leading to 91.4% selectivity. The photocatalytic valorization of polylactic acid (PLA) into high-value pyruvic acid (PA) represents a sustainable pathway toward a circular carbon economy. However, the generation of non-selective reactive oxygen species (ROS) typically compromises product selectivity. Herein, we report a sulfur-vacancy-modified CdS photocatalyst (CdS v ), which was synthesized via a facile co-precipitation method and engineered to precisely regulate ROS generation. Experimental and theoretical analyses reveal sulfur vacancies (S v ) enrich the localized electron density at adjacent Cd sites. This electronic modulation promotes molecular oxygen (O 2 ) capture at these Cd centers and concurrently drives a shift in the binding geometry from a side-on to an end-on orientation. The specific adsorption configuration significantly inhibits O O bond cleavage to form hydroxyl radicals (•OH) through the oxygen reduction reaction, thereby effectively suppressing the overoxidation of PA. Consequently, remarkable PA generation efficiency is achieved over the optimized CdS v catalyst, yielding 13.2 mmol g −1 h −1 with a high selectivity of 91.4%, which significantly surpasses most previously reported results. This work provides a molecular-level paradigm for the selective upcycling of plastic waste by regulating the formation of specific ROS through vacancy engineering. Sulfur vacancies intrinsically enrich the electron density at proximal Cd centers, thereby favoring molecular oxygen (O 2 ) adsorption and shifting its adsorption configuration from side-on to end-on. This specific adsorption configuration of O 2 suppresses O O bond cleavage during the oxygen reduction reaction, thereby steering the pathway toward preferential superoxide radicals (•O 2 − ) generation and mitigating the hydroxyl radical (•OH)-induced over-oxidation. Download: Download high-res image (160KB) Download: Download full-size image
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CHEMICAL ENGINEERING JOURNAL
·
2026
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IF 12.5
Jiahui Li,Fulin Li,Yunzheng Li,Yuqing Wan,Xingran Xu,Xiang Zou
[diOTMG]Cl@Zr-bptc porous liquid (PL) was successfully prepared. • PL enhanced succinic acid yield 8.71-fold compared to organic amine. • 99.98% pure succinic acid was obtained by PL extraction and crystallization. • Carboxylic acids are separated via affinity and molecular size differences. Global environmental deterioration and plastic pollution drive the demand for biodegradable polymers, which rely on ultrapure monomer, such as succinic acid (SA). However, current bio-SA purification suffers from low purity (94–98%) and complex multistep processes due to similar affinity of homologues. Here, we introduce a type III porous liquid (PL) composed of ionic liquid [diOTMG]Cl and metal-organic framework Zr-bptc for SA purification, achieving 99.98 ± 0.01 wt% SA purity with 84.15% yield after crystallization. This represents an 8.71-fold yield increase in yield and 6.55-fold improvement in selectivity over tri-n-octylamine. Laboratory-scale assessment confirms the PL solution as a sustainable process. Mechanistically, carboxylic acids are extracted synergistically through hydrogen bonding/anion exchange, while Grand Canonical Monte Carlo (GCMC) simulations showed selective adsorption of acetic acid in Zr-bptc pores. Weak interactions and kinetic size sieving ensure high SA purity. This PL provides an efficient solution for producing polymer-grade monomers, addressing the long-standing challenge in fermented homologue separation. Download: Download high-res image (122KB) Download: Download full-size image
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INORGANIC CHEMISTRY
·
2026
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IF 4.6
Junhui He,Mingming Zhang,Xiaochu Zheng,Jianfeng Li,Linjuan Yang,Cong Luo,Xudong Cui,Zhuoyu Ji,Daopeng Sheng,Xiaofang Feng,Tao Chen,Wenkun Zhu
The synergistic coupling of nonthermal plasma (NTP) with catalysts offers a promising route for converting CO2/H2O into high-value-added chemicals, but its efficiency is hindered by low-activity catalysts and electron quenching by gaseous H2O. Herein, we propose a “surface electron-enriched microenvironment” strategy to construct a UiO-66(SH)2 catalyst to boost NPT CO2 conversion. Under dielectric barrier discharge (DBD) plasma conditions, the UiO-66(SH)2 catalytic system achieves a CO2 conversion rate of 42.19%, which is 1.88 and 38.87 times higher than that of the unmodified UiO-66 system and plasma-only system, respectively. CO was identified as the dominant carbon-containing product with a selectivity of 82.39%, along with CH4 and trace C2–C3 hydrocarbons. Theoretical calculations and experimental results confirm that the thiol groups in UiO-66(SH)2 create an electron-enriched microenvironment, which significantly enhances the adsorption and activation of CO2 while effectively suppressing the electron quenching effect of gaseous H2O on a plasma-induced CO2 dissociation process. Furthermore, thiol functional groups create an electron-rich microenvironment, effectively reducing the free-energy barrier for the formation of the key intermediate *COOH and thereby accelerating CO2 conversion kinetics. This research provides a rational strategy for achieving efficient and highly selective plasma catalytic CO2 conversion through the metal–organic frameworks (MOFs) functionalization.
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危险品化学品经营许可证（带存储）