ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2022
·
IF 7.129
Lin-Lin Hu,Hong-Ge Li,Bi-Yun Liao,Yi Xu,Shao-Chen Sun,Jun-Li Wang
Nonylphenol (NP) is an environmental endocrine disruptor, which is mainly used in the production of surfactants, lubricants, additives, pesticides, and emulsifiers. NP is widely found in sewage and sludge, which has neurotoxicity, immunotoxicity, metabolic toxicity and reproductive toxicity. In this study, we investigated the effects of NP exposure on mammalian oocyte quality from organelle aspects with mouse in vivo model. The results showed that the ovarian weight of mice exposed to 500 μg/L NP for 4 weeks increased and the development ability of oocytes decreased, showing with lower rate of polar body extrusion. Further analysis indicated that exposure to NP caused the abnormal distribution of mitochondria, following with altered membrane potential drop. NP exposure disrupted the spindle periphery localization of ER, and affected the expression of GRP78 for the induction of ER stress. Moreover, Golgi apparatus fragment in the oocytes was observed, and Rab11-based vesicle transport was disturbed. We also found that the protein degradation might be affected since LAMP2 expression increased and LC3 decreased, indicating the lysosome and autophagy dysfunction. Taken together, our findings suggested that the exposure of NP to mice in vivo affected oocyte quality through its effects on the distribution and function of organelles.
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TALANTA
·
2023
·
IF 6.1
Haoyu Long,Yanhao Jiang,Yanjuan Liu,Yuefei Zhang,Wei Chen,Sheng Tang
In this work, 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TAPT) and 1,3,5-tris(4-formylphenyl)benzene (TFPB) were used as monomers to construct a triazine-containing imine-linked covalent organic framework (COF), which was then bonded onto the surface of aldehydized silica (SiO 2 –CHO), and finally a COF@silica composite material (TAPT-TFPB COF@SiO 2 ) was successfully prepared. The chromatographic separation performance of SiO 2 –CHO, TAPT-TFPB COF@SiO 2 and TAPT-TFPB COF@SiO 2 /SiO 2 –CHO (80/20, mass ratio) was evaluated and compared. It was found that separation efficiency was obviously enhanced by adding an appropriate amount of SiO 2 –CHO into TAPT-TFPB COF@SiO 2 . The obtained TAPT-TFPB COF@SiO 2 /SiO 2 –CHO showed more favorable separation ability than SiO 2 –CHO and TAPT-TFPB COF@SiO 2 . Various aromatic compounds including alkylbenzenes , polycyclic aromatic hydrocarbons , environmental endocrine disruptors , foodborne stimulants and phenyl ketones were effectively separated on the TAPT-TFPB COF@SiO 2 /SiO 2 –CHO column in reversed phase chromatography mode. The silica microspheres surface-modified with triazine-containing imine-linked COFs proved to be a new type of promising chromatographic packing materials.
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FOOD AND CHEMICAL TOXICOLOGY
·
2023
·
IF 4.3
Huiying Huang,Jian Shi,Zhongyi Li,Yifeng Rang,Weiye Li,Xueman Xiao,Congying Chen,Chunhong Liu
Nonylphenol (NP) exposure can trigger neurotoxicity and cause learning and memory impairment. Nicotinamide mononucleotide (NMN) has a therapeutic effect on neurodegenerative diseases , but the role of NMN on NP-induced learning and memory impairment is not known. Here, we examined the mitigative effect of NMN on the impaired learning and memory ability of rats exposed to NP. The NP impaired learning and memory in rats, while the low-dose intervention with NMN significantly prolonged the step-through latency of the PAT and improved the NAMPT and NMNAT1 content in brain tissue. At the same time, the NMN intervention also increased the content of 5-HTR 1A , 5-HTR 4 , and 5-HTR 6 related to learning and memory in the hippocampus. In line with this, we found that the NMN intervention activated the SIRT1/MAO-A pathway in brain tissue. NMN intervention, especially at 125 mg/kg doses, may improve rats’ NP-induced learning and memory impairment via the central 5-HT system and the NAD + /SIRT1/MAO-A pathway in the brain.
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MICROPOROUS AND MESOPOROUS MATERIALS
·
2021
·
IF 5.455
Jie Liu,Ziqian Wang,Qiuliang Wang,Kailai Zhang,Yali Luo,Yunfei Liu,Yinong Lyu,Bei Huang
Porous carbon with abundant nitrogen doping (C-PCTF) was obtained by using porphyrin-based covalent triazine framework (PCTF) as the carbonization precursor. As expected, C-PCTF inherits the porous structure and the chemical composition of the PCTF . Due to the high surface area and accessible nitrogen sites, the carbon material can be employed as a superior supporting substrate to immobilize Au and Ag nanoparticles . Both the Au@C-PCTF and Ag@C-PCTF nanocatalysts show good catalytic activity in the reduction of 4-nitrophenol. Especially for Ag@C-PCTF, the catalytic activity is higher than most of other metal-catalysts reported previously. This study would provide a new strategy to use various porous organic polymers in fabricating carbon-supported heterogeneous catalysts.
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Polymer Chemistry
·
2021
·Vol. 12
·期 47
·6903-6913
·
IF 5.582
Si Wu,Lei Lei,Yuzheng Xia,Susan Oliver,Xiaonong Chen,Cyrille Boyer,Zhiyong Nie,Shuxian Shi
Multifunctional hybrid particles have been attracting tremendous interest over decades. Herein we demonstrated the functionality of poly(N-isopropylacrylamide) immobilized gold nanoparticles (PNIPAMs-AuNP) as both colorimetric temperature-sensors and reusable temperature-switchable catalysts. The hybrid nanoparticles composed of a gold core (diameter = 14.8 ± 0.2 nm) and a PNIPAM shell (thickness = 2.6 ± 0.2 nm) exhibit reversible color changes and size adjustment in aqueous dispersion upon salt and environment temperature variation. Visual observation or colorimetric monitoring of the PNIPAMs-AuNP dispersion through a UV-vis spectrometer, we were able to detect and calibrate the changes in color between red–purple–red as the environmental temperature changes. The synergetic effect of different types of salt has been systematically investigated. It is observed that the sensitivity of the colorimetric temperature-sensor could be significantly improved by adding salts (NaCl < KCl < MgCl2) or controlling salt concentrations. Moreover, the temperature-switchable PNIPAMs-AuNP hybrid nanoparticles were applied to catalyze the reduction reaction of 4-nitrophenol to 4-aminophenol. The reduction process can be sped-up or slowed-down by controlling the system temperature, which switches the catalytic AuNPs surface on and off as the reversible PNIPAM chains collapse (hydrodynamic size = 41 ± 1 nm) and expand (49 ± 1 nm). Moreover, the switchable catalysts can be recycled through centrifugation and reused. The polymer-engineered core–shell PNIPAMs-AuNP hybrid nanoparticles are promising to enrich the development of temperature-responsive systems such as ambient temperature alarms and smart catalysts.
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Materials Today Chemistry
·
2021
·
IF 8.301
X. Jiao,H. Li,X. Cheng
This article deals with three cellulose-based fluorescent macromolecular sensors by introducing 1,8-naphthalimide fluorophore to cellulose . First, through the etherification reaction of cellulose with BrCH 2 CH 2 NH 2 , –NH 2 group–bearing cellulose CS 1 was obtained. Then, the –NH 2 group reacts with 4-bromo-1,8-naphthalic anhydride to synthesize a naphthalimide cellulose derivative ( CS 2 ). Finally, the recognition group was introduced by substituting Br atoms, and three cellulose fluorescent probes ( CS 3 , CS 4 , and CS 5 ) were obtained eventually. Structure and fluorescence properties of the macromolecular sensors were characterized and confirmed. Fluorescence detection measurements show that these probes can be used as selective and sensitive fluorescent sensors to 2,4,6-trinitrophenol (TNP). The detection limits are 0.52 μM, 0.76 μM, and 0.81 μM, indicating good detection performance. This work provides a new method for the selective detection of TNP and also a method to enlarge the application scope of cellulose.
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NANOTECHNOLOGY
·
2014
·Vol. 25
·期 35
·355702
·
IF 3.672
Dongyue Su,Xin Yang,Qingdong Xia,Qi Zhang,Fang Chai,Chungang Wang,Fengyu Qu
In this research, folic acid functionalized silver nanoparticles (FA-AgNPs) were selected as a colorimetric and a 'turn on' fluorescent sensor for detecting Hg2+. After being added into Hg2+, AgNPs can emit stable fluorescence at 440 nm when the excitation wavelength is selected at 275 nm. The absorbance and fluorescence of the FA-AgNPs could reflect the concentration of the Hg2+ ions. Thus, we developed a simple, sensitive analytical method to detect Hg2+ based on the colorimetric and fluorescence enhancement of FA-AgNPs. The sensor exhibits two linear response ranges between absorbance and fluorescence intensity with Hg2+ concentration, respectively. Meanwhile, a detection limit of 1 nM is estimated based on the linear relationship between responses with a concentration of Hg2+. The high specificity of Hg2+ with FA-AgNPs interactions provided the excellent selectivity towards detecting Hg2+ over other metal ions (Pb2+, Mg2+, Zn2+, Ni2+, Cu2+, Co2+, Ca2+, Mn2+, Fe2+, Cd2+, Ba2+, Cr6+ and Cr3+). This will provide a simple, effective and multifunctional colorimetric and fluorescent sensor for on-site and real-time Hg2+ ion detection. The proposed method can be applied to the analysis of trace Hg2+ in lake water. Additionally, the FA-AgNPs can be used as efficient catalyst for the reduction of 4-nitrophenol and potassium hexacyanoferrate (III).
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Science Bulletin
·
2016
·
IF 0
Lidan Xu,Min Hong,Yongliang Wang,Ming Li,Haibo Li,Madhavan P.N. Nair,Chen-Zhong Li
In this work, we demonstrated a simple and efficacious two-step method for the synthesis of Ag@Au core–shell nanoparticles (Ag@AuNPs) and the Ag/Au hollow nanocages (Ag/AuNCs) with Ag nanoparticles (AgNPs) as seeds by adjusting pH, and the preparation of hybrid Ag@AuNPs- or Ag/AuNCs-graphene oxide nanocomposites (Ag@AuNPs-GO or Ag/AuNCs-GO) based on the self-assembly. It was noticed from the electrostatic assembly experiment that the loading amount of Ag/AuNCs on GO nanosheet was more than that of Ag@AuNPs. The as-synthesized hybrid materials were characterized by transmission electron microscopy , atomic force microscopy , ζ-potential, high-angle annular dark-field scanning transmission electron microscopy, thermogravimetric analyzer and X-ray diffraction. Catalytic activities of Ag@AuNPs, Ag/AuNCs and Ag/AuNCs-GO nanostructures were investigated in the reduction of 4-, 3- or 2-nitrophenol to 4-, 3- or 2-aminophenol, and on the basis of comparative kinetic studies the following trend was obtained for the related catalytic activity: Ag/AuNCs-GO > Ag/AuNCs > Ag@AuNPs. These observations were attributed to the simultaneous effects of surface area available for catalytic reaction and composition of the hybrid nanostructures.
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APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Yan-Feng Huang,Xiao-Yi Sun,Shu-Hui Huo,Ying Li,Chongli Zhong
The high performance of catalysts relies largely on the meticulous design of hierarchical hollow micro/nanostructures with more active sites and superb structural tenability. Herein, we developed a simple strategy to design and fabricate CoFe 2 O 4 /CuO (sub)microcages using core-shell dual-MOF heterostructures (Fe II -Co PBAs@HKUST-1) as both the precursor and self-sacrificing template. The derivation of metal oxide composites from dual-MOF heterostructures is challenging, and this method could overcome the difficulty caused by the possible lattice mismatch between the different MOFs . Uniform core-shell dual-MOF structures Fe II -Co PBAs@HKUST-1 were first fabricated and then converted to CoFe 2 O 4 /CuO (sub)microcages by thermal annealing in air. The resulting CoFe 2 O 4 /CuO (sub)microcages were extensively characterized and exhibited remarkable catalytic performance with an excellent stability and magnetic recyclability for the reduction of 4-nitrophenol to 4-aminophenol by NaBH 4 . In addition, CoFe 2 O / CuO (sub)microcages were also found to be highly active for catalytic reduction of methylene blue (MB) by NaBH 4 in an aqueous solution. The results show that CoFe 2 O 4 /CuO (sub)microcages have potential application for organic pollutants degradation and environmental rehabilitation.
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RSC Advances
·
2015
·Vol. 5
·期 126
·104239-104244
·
IF 3.84
Lei Liu,Yili Zhao,Qian Chen,Xiangyang Shi,Mingwu Shen
A facile approach to assembling polyethyleneimine (PEI)-entrapped gold nanoparticles (Au PENPs) onto filter paper is reported. In this work, Au PENPs with an Au core size of 3.2 ± 0.8 nm were formed using PEI as a template, followed by adsorption onto filter paper. The formed Au PENP-containing filter paper was characterized by various techniques. We show that the Au PENPs are able to be adsorbed onto filter paper likely due to the microfibrous structure of the paper and the electrostatic interaction between the positively charged Au PENPs and the negatively charged filter paper. Furthermore, we demonstrate that the Au PENP-assembled filter paper displays an excellent catalytic activity and reusability to converting 4-nitrophenol to 4-aminophenol. Such a development of Au PENP-assembled filter paper may be applicable for the immobilization of other metal NPs onto filter paper for various applications in catalysis, sensing, and biomedical sciences.
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INDUSTRIAL CROPS AND PRODUCTS
·
2022
·
IF 6.449
Run-Ze Hu,Xiao-Qi Zhang,Xiao-Hui Yao,Jia-Xin Yang,En-Jiang Liu,Tao Chen,Yu-Jie Fu,Wei-Guo Zhao,Dong-Yang Zhang
To remove the pollutants nitrophenol in wastewater, a bio-inspired dynamic filter (CE-Pd-EPI) with in-situ synthesized palladium nanoparticles (PdNPs) was prepared via chemical cross-linking and freeze casting. This bio-inspired filter has a hierarchical dual-porous structure with micron-scale unidirectional channels and nanoscale pores. This hierarchical porous structure facilitates rapid mass transfer of the liquid. Therefore, this filter can completely reduce 4-nitrophenol (4-NP, 2 mM) in 3 min. The rate constant ( k ) and turnover frequency (TOF) are 2.42 min −1 and 13.17 min −1 , respectively, which are better than most reports so far. Moreover, this filter can also instantaneously catalyze the reduction of methylene blue (MB) to colorless. After five cycles, the conversion of 4-NP and MB by the filter still reaches 99.9%, demonstrating its excellent catalytic stability and reusability. In addition, in a continuous fluid catalytic system this filter has a low pressure (only 0.84 kPa) due to its bio-inspired unidirectional channel structure, which is extremely important for continuous industrial application. This bio-inspired dynamic filter has a guiding significance for the removal of organic pollutants in wastewater in industrial applications. Therefore, the bio-inspired dynamic filter described in this study has a great potential in the field of water treatment and environmental protection.
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CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Yuanqing Luo,Xiaoyong Zhao,Pengfei Cai,Yuanjiang Pan
A facile one-pot synthetic method for preparing gold nanoparticles by employing sugammadex (SUG), a carboxylic acid functionalized γ -cyclodextrin derivative, as reducing-cum-stabilizing agent herein was reported for the first time. The SUG protected gold nanoparticles (SUG-AuNPs) can work as a colorimetric sensor for visual chiral recognition of α -amino acids enantiomers, especially for lysine (Lys) and asparagine (Asn) enantiomers. The chiral recognition assay was successfully applied to determining the enantiometric excess of L-Lys and L-Asn ranging from −100 % to 100 % respectively. Moreover, the prepared SUG-AuNPs was found to exhibit efficient catalytic activity towards the reduction of toxic 4-nitrophenol by NaBH 4 and the efficiency of the system was further demonstrated through the reduction of other typical nitroaromatics under mild condition. The as-synthesized SUG-AuNPs shows good performance for both chiral sensing and reduction activity and thus may facilitate the practical application in the area of both chiral discrimination and catalysis.
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