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Foods · 2025 ·Vol. 14 ·期 11 ·1894 · IF 5.1

Flavor Quality and Lipid-Lowering Function of Mixed Fermented Pu-erh Tea with Various Monascus Species

Xiaomin Chen,Yao Hu,Zhen Zeng,Xu Zhang,Yahui Huang

As a potential raw material with a variety of bioactive compounds, Pu-erh raw tea can produce rich flavor and health benefits through natural fermentation or microbial fermentation in traditional processing. However, the traditional fermentation process has some problems such as a long fermentation period and unstable quality. Monascus, a kind of fungus used in both medicine and food, has been proved to have many beneficial effects such as lowering cholesterol and regulating blood lipids. Therefore, in this study we investigated whether the fermentation of mixed monascus could significantly improve the flavor quality and lipid-lowering activity of Pu-erh raw tea. We added four kinds of monascus to unfermented Pu-erh raw tea (UT) to obtain a fermented Pu-erh raw tea (FT). The quality of the two tea samples was determined and an in vitro lipid-lowering experiment was conducted. The results show that the contents of water extractives, flavone, trans-catechins (GCG and CG), theabrownins, and caffeine in FT are significantly higher than those in UT, increasing by 19.41%, 14.47%, 18.76%, 29.82%, and 10.67%, respectively. In terms of aroma, linalool was the characteristic compound of UT, presenting a floral note. D-Limonene was the key characteristic substance of FT, manifested as lemon, toast, and wood. In terms of taste, FT has a high content of bitter amino acids and caffeine, a low content of catechins, and is rich in carbohydrate substances, forming a characteristic mild and mellow slightly bitter taste with reduced astringency. In addition, the relative contents of active substances with lipid-lowering effects such as quercetin, quercitrin, ascorbic acid, and sorbitol in FT were higher than those in UT, increasing by 83.09%, 81.73%, 89.86%, and 92.76%, respectively. The effect of FT on regulating cellular lipid metabolism was superior to UT based on cell experiments. The research results provide a scientific basis for the deep processing and functional development of Pu-erh raw tea.

CAS / MDL: 67-56-1 67-63-0
研究领域: 食品科学 · 微生物学 · 生物化学
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY · 2021 · IF 5.302

Effect of SiCnws on flexural strength of SiCf/HfC-SiC composites after impact and ablation

Tao Feng,Wanbo Hou,Mingde Tong,Hejun Li,Hongjiao Lin,Shifeng Wen

SiC nanowires (SiC nws ) modified SiC f /HfC-SiC composites were prepared by precursor infiltration and pyrolysis (PIP) and chemical vapor infiltration (CVI) methods. The microstructure, flexural strengths, impact and impact-ablation tests of the composites with and without SiC nws were investigated. The results showed that after introducing SiC nws , not only the retention rate of HfC ceramic produced by PIP was increased obviously, but also the fracture displacement of the modified composites was reduced due to the enhancement effect of SiC nws at interface between SiC fiber and matrix. After impact and impact-ablation, the strength retention of SiC nws modified composites was 91.6 % and 69.1 % respectively, higher than that of the composites without SiC nws (85.2 % and 54.8 %). As the impact resistance of the modified composites was improved by the pull-out and bridging of SiC nws , the ablation resistance of the impacted composites was enhanced as well.

研究领域: 材料科学 · 航空航天工程
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LWT-FOOD SCIENCE AND TECHNOLOGY · 2021 · IF 4.952

Unraveling the mystery of ‘bask in daytime and dewed at night’ technique in doubanjiang (broad bean paste) fermentation

Shuai Zhao,Chengtuo Niu,Jingyi Suo,Youlong Zan,Yuehu Wei,Feiyun Zheng,Chunfeng Liu,Jinjing Wang,Qi Li

‘Bask in daytime and dewed at night’ technique is traditionally used in doubanjiang fermentation, however, the underlying mechanism behind this technique is still unrevealed. This study aimed to elaborate the roles of three key indexes in this technique, that are air, sunlight, and mash turnover, on doubanjiang quality through the design of doubanjiang fermentation. The results showed that the exposure to air or sunlight was beneficial for doubanjiang to yield reddish-brown luster color, less acidity and balanced flavor. On the contrary, blocking of air and sunlight could accumulate higher acidity (4.75 ± 0.01 g/100g dw ), amino nitrogen (2.08 ± 0.07 g/100g dw ), alcohols (36.9 g/kg) and esters (26.9 g/kg). Regular mash turnover was mainly involved in making different mash layers exposure to air or sunlight equally through homogenizing mash layers. Different conditions also have been suggested to affect the microbiota dynamics by amplicon sequencing and RT-qPCR. Based on RDA analysis, Pediococcus , Meyerozyma , Bacillus and Zygosaccharomyces were predicted to be related to the changes of physicochemical properties or volatile compounds in different conditions, and their function was validated by simulated fermentation. This study would unravel the underlying scientific meaning of ‘bask in daytime and dewed at night’ technique in doubanjiang fermentation.

CAS / MDL: 123-96-6
研究领域: 食品科学 · 微生物学
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LWT-FOOD SCIENCE AND TECHNOLOGY · 2019 · IF 3.714

Phenolic profile and antioxidant activity of Chinese rice wine fermented with different rice materials and starters

Haiying Cai,Qi Zhang,Lingzhi Shen,Jie Luo,Ruiyu Zhu,Jianwei Mao,Minjie Zhao,Chenggang Cai

The polyphenolic compounds in wines are beneficial to human health. To better understand the effect of different factors on the phenolics and antioxidant activities of wine during rice wine fermentation, 6 rice materials and 7 rice wine starters from rural areas were used to ferment Chinese rice wine. The results showed that black rice and the starter O4 were preferred for the optimum polyphenolic content and antioxidant activity, respectively. In addition, the results indicated that the polyphenolics of the rice wines were mainly derived from their plant materials and that various rice materials could result in drastically different wine quality. In contrast, the total polyphenol contents could be less significantly changed by using different starters. The antioxidant activity results of these fermented wines were consistent with the results of the total polyphenol contents. The rice wines produced using 6 different rice materials were significantly different in antioxidant activity measured by ABTS and FRAP assay . Similar to the results of the total polyphenol content and the antioxidant activity, the wine samples with different rice materials showed significantly different polyphenolic profiles compared with those of the rice wine group with different starters. These results suggested that rice materials and starters have different effects on polyphenol extraction and conversion of rice wines.

研究领域: 食品科学 · 生物化学
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ANNALEN DER PHYSIK · 2021 ·Vol. 533 ·期 2 ·2000464 · IF 2.987

Numerically Denoising Thermally Tunable and Thickness-Dependent Terahertz Signals in ErFeO3 Based on Bézier Curves and B-Splines

Xinxi Zeng,Han Zhang,Xiaoqing Xi,Bo Li,Ji Zhou

The terahertz (THz) spectral range offers a platform for experimentally collecting electromagnetic pulses to analyze the intrinsic resonances of matter and has become an important field for applying intrinsic responses to future information devices. However, a lack of numerical methods for signal denoising exists in the knowledge of the THz spectral range. In this paper, numerical methods that employ the Bézier curve and its generalization ( B -spline) to denoise thermally tunable and thickness-dependent terahertz signals are proposed. Different thicknesses of ErFeO 3 are chosen and prepared. Both Bézier curves and B -splines have the ability to denoise the signals and the effect of the Bézier curves on the noise is close to but slightly less than that of the B -splines. Additionally, the B -splines show a better noise reduction effect and have better signal strength stability and robustness than do the Bézier curves. Thus, B -splines are applied to process the raw data, and quantitative insight into the trend of the resonant frequencies, peak heights, and transmittances of antiferromagnetic resonance and ferromagnetic resonance with temperature is obtained.

CAS / MDL: 1309-37-1 20344-49-4
研究领域: 物理学 · 材料科学
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JOURNAL OF SEPARATION SCIENCE · 2022 ·Vol. 45 ·期 18 ·3404-3411 · IF 3.614

The presence and transfer characteristics of aflatoxins in medicinal herbs: From raw materials to edible dispensing granules

Yudan Wang,Cheng Zhang,Lei Zhang,Zhen OuYang,Ming Zhao,Jiaoyang Luo,Meihua Yang

In this study, a sensitive and accurate immunoaffinity columns coupled with high-performance liquid chromatography method was established to monitor the presence of aflatoxins—aflatoxin B 1 , aflatoxin B 2 , aflatoxin G 1 , and aflatoxin G 2 —in different medicinal herbs. The proposed method was found to be suitable for the detection of aflatoxins in eight kinds of herbs and their corresponding granules. Two batches of Arecae semen were positive for aflatoxins, with high residue levels of different aflatoxins. To better understand the presence and transfer of aflatoxins during the formulation of dispensing granules from the herbs, the aflatoxins-free herbs were artificially inoculated with Aspergillus flavus to explore aflatoxins production. Both aflatoxin B 1 and aflatoxin B 2 were detected in all inoculated samples, while aflatoxin G 2 was only detected in Astragali radix samples. Additionally, the presence of aflatoxin B 1 was extremely high compared to other aflatoxins. More specifically, the transfer rate of the aflatoxin B 1 and the total aflatoxins from original herbs to granules were both approximately 40%. These findings indicated that the preparation of herbs into dispensing granules reduced the content of aflatoxins. The high-level presence of aflatoxins in inoculated herbs indicated that attention is needed to the safety of A. flavus -contaminated herbs.

CAS / MDL: 9005-64-5 9004-53-9
研究领域: 药学 · 食品安全 · 植物学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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Foods · 2022 ·Vol. 11 ·期 15 ·2190 · IF 5.561

Improving Soy Sauce Aroma Using High Hydrostatic Pressure and the Preliminary Mechanism

Yaqiong Zhang,Zhi-Hong Zhang,Ronghai He,Riyi Xu,Lei Zhang,Xianli Gao

Using high hydrostatic pressure (HHP) to treat liquid foods can improve their aroma; however, no information about the effects of HHP on soy sauce aroma has yet been reported. The effects of HHP on the aroma of soy sauce fermented for 30 d were investigated using quantitative descriptive analysis (QDA), SPME–GC–olfactometry/MS, hierarchical cluster analysis (HCA) and principal component analysis (PCA). Results showed that the pressure used during HHP treatment had a greater influence on soy sauce aroma than the duration of HHP. Compared to the control, soy sauce that was treated with HHP at 400 MPa for 30 min (HHP400–30) obtained the highest sensory score (33% higher) by increasing its sour (7%), malty (9%), floral (27%) and caramel-like (47%) aromas, while decreasing its alcoholic (6%), fruity (6%) and smoky (12%) aromas; moreover, the aroma of HHP400–30 soy sauce was comparable with that of soy sauce fermented for 180 d. Further investigation demonstrated that HHP (400 MPa/30 min) enhanced the OAVs of compounds with sour (19%), malty (37%), floral (37%), caramel-like (49%) and other aromas (118%), and lowered the OAVs of compounds with alcoholic (5%), fruity (12%) and smoky (17%) aromas. These results were consistent with the results of the QDA. HHP treatment positively regulated the Maillard, oxidation and hydrolysis reactions in raw soy sauce, which resulted in the improvement and accelerated formation of raw soy sauce aroma. HHP was capable of simultaneously improving raw soy sauce aroma while accelerating its aroma formation, and this could treatment become a new alternative process involved in the production of high-quality soy sauce.Keywords:soy sauce;high hydrostatic pressure;aroma compound;Aspergillus oryzae;soybean

研究领域: 食品科学 · 微生物学
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Scientific Reports · 2021 ·Vol. 11 ·期 1 ·1-8 · IF 4.38

Identification and in vitro antifungal susceptibility of causative agents of onychomycosis due to Aspergillus species in Mashhad, Iran

Xu Xue,Naseri Ali,Houbraken Jos,Akbari Farzaneh,Wang Xiaodong,Zhao Rongfen,Zhang Hong,Najafzadeh Mohammad Javad,Deng Shuwen

Aspergillus species are emerging causative agents of non-dermatophyte mold onychomycosis. In this study, 48 Aspergillus isolates were obtained from patients with onychomycosis in Mashhad, Iran, during 2015–2018. The aim is to identify the Aspergillus isolates to the species level by using partial calmodulin and beta-tubulin gene sequencing and MALDI-TOF MS, and to evaluate their in vitro susceptibility to ten antifungal drugs: terbinafine, itraconazole, voriconazole, posaconazole, ravuconazole, isavuconazole, caspofungin, micafungin, anidulafungin and amphotericin B according to CLSI M38-A3. Our results indicate that A.flavus (n = 38, 79%) is the most common Aspergillus species causing onychomycosis in Mashhad, Iran. Other detected species were A. terreus (n = 3), A. tubingensis (n = 2), A. niger (n = 1), A. welwitschiae (n = 1), A. minisclerotigenes (n = 1), A. citrinoterreus (n = 1) and A. ochraceus (n = 1). Aspergillus flavus , A. terreus and A. niger isolates were correctly identified at the species level by MALDI-TOF MS, while all cryptic species were misidentified. In conclusion, A. flavus is the predominant Aspergillus species causing onychomycosis due to Aspergillus spp. in Mashhad, Iran. MALDI-TOF MS holds promise as a fast and accurate identification tool, particularly for common Aspergillus species. It is important that the current database of reference spectra, representing different Aspergillus species is expanded to increase the precision of the species-level identification. Terbinafine, posaconazole and echinocandins were i n vitro most active against the studies Aspergillus isolates and terbinafine could be the first choice for treatment of onychomycosis due to Aspergillus .

CAS / MDL: 91161-71-6
研究领域: 医学 · 真菌学 · 临床微生物学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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Fermentation-Basel · 2023 ·Vol. 9 ·期 1 ·50 · IF 3.7

Effect of Aspergillus niger Fermentation on the Metabolites in Corn Stalks

Zhen Fan,Tianming Chen,Guolin Cai,Xiaoyu Huang,Suchuan Zhong,Xiaoming Li,Enping Zhang

Fermentation has been considered as an effective means to improve the feed nutrient digestibility of corn stalks, and it is beneficial to animal growth performance and health. The beneficial functions of fermented corn stalks are related to the variety of metabolites produced through fermentation, but the nature of these components is still unclear. In this study, gas chromatography–mass spectrometry, combined with principal component analysis and partial least squares discriminant analysis, was used to explore the differential metabolites of corn stalks before and afterAspergillus nigerfermentation. A total of 32 potential characteristic compounds were obtained, mainly including sugar and glycoside derivatives, organic acids and their derivatives, alcohol compounds, benzene and its substituted derivatives, amino acids, phenolic compounds, and flavonoids. Compared with the metabolites in corn straw before fermentation, the relative content of D-threitol, mannitol-1-phosphate, coniferin, citrazinic, oxoglutaric acid, chenodeoxycholic acid, naproxen, 5-aminovaleric acid, vanillin, catechin, and UDP-glucuronic acid was significantly increased, and the relative content ofN-acetylgalactosamine, heneicosanoic acid, chlorogenic acid, and adenosine was significantly decreased. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that 20 metabolic pathways corresponded to the differential characteristic metabolites. The results of this study will provide theoretical support for the quality evaluation of fermented corn stalks and high-value product development in the future.Keywords:Aspergillus niger;fermentation;metabolomics;corn straw;metabolites

CAS / MDL: 110-86-1
研究领域: 微生物学 · 动物营养学
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Foods · 2024 ·Vol. 13 ·期 8 ·1158 · IF 4.7

Improving Soluble Phenolic Profile and Antioxidant Activity of Grape Pomace Seeds through Fungal Solid-State Fermentation

Yuzhu Zhao,Doudou Liu,Jiaxuan Zhang,Jiaxin Shen,Jiamin Cao,Huawei Gu,Mengqing Cui,Ling He,Gong Chen,Shuwen Liu,Kan Shi

Grape pomace seeds contain abundant phenolic compounds, which are also present in both soluble and insoluble forms, similar to many other plant matrices. To further increase the extractable soluble phenolics and their antioxidant activities, grape pomace seeds were fermented with different fungi. Results showed that solid-state fermentation (SSF) withAspergillus niger,Monascus anka, andEurotium cristatumat 28 °C and 65% humidity had a significantly positive impact on the release of soluble phenolics in grape pomace seeds. Specifically, SSF withM. ankaincreased the soluble phenolic contents by 6.42 times (calculated as total phenolic content) and 6.68 times (calculated as total flavonoid content), leading to an overall improvement of antioxidant activities, including DPPH (increased by 2.14 times) and ABTS (increased by 3.64 times) radical scavenging activity. Furthermore, substantial changes were observed in the composition and content of individual phenolic compounds in the soluble fraction, with significantly heightened levels of specific phenolics such as chlorogenic acid, syringic acid, ferulic acid, epicatechin gallate, and resveratrol. Notably, duringM. ankaSSF, positive correlations were identified between the soluble phenolic content and hydrolase activities. In particular, there is a strong positive correlation between glycosidase and soluble phenols (r = 0.900). The findings present an effective strategy for improving the soluble phenolic profiles and bioactivities of grape pomace seeds through fungal SSF, thereby facilitating the valorization of winemaking by-products.

CAS / MDL: 154-23-4 149-91-7
研究领域: 食品科学 · 生物技术 · 化学 · 农业
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NATURE MATERIALS · 2025 ·Vol. 24 ·期 11 ·1716-1725 · IF 38.5

Near-100% spontaneous rolling up of polar van der Waals materials

Zhang Zhi,Zhang Yuwei,Lu Kangjun,Zhang Jun-Jie,Zhang Nannan,Feng Rui,Ye Haoran,Zhou Xiaoli,Li Linglong,Wan Dongyang,Lu Junpeng,Ni Zhenhua,Wang Jinlan,Chen Qian,Lu Jiong,Li Zejun

Rolling two-dimensional materials into one-dimensional nanoscrolls introduces curvature, chirality and symmetry breaking, enabling emergent properties. Conventional methods relying on external driving forces, however, exhibit poor control, low yield and limited reproducibility. Here we report spontaneous scrolling in polar van der Waals materials via an electrochemical intercalation/exfoliation process, enabling scalable nanoscroll production. This self-rolling is driven intrinsically by out-of-plane electric polarization ( P ⊥ ), where the magnitude of P ⊥ is modulated by the intercalant size. Validated across eight polar materials, this approach achieves virtually 100% yield and reproducibility with defined scrolling direction, surpassing external driving force limitations. The nanoscrolls exhibit layer-independent inversion symmetry breaking and coherently enhanced second-harmonic generation, exceeding two-dimensional flakes by ~100-fold and rivalling leading two-dimensional nonlinear materials. Electrochemical initiation further facilitates metal-ion co-intercalation, yielding ten hybrid nanoscroll architectures. These findings establish a scalable route to create one-dimensional nanostructures and hybrid heterostructures, paving the way for designer quantum solids and van der Waals superlattices in quantum nanodevices.

研究领域: 材料科学 · 纳米技术 · 凝聚态物理 · 非线性光学 · 量子材料
✓ 已验证 DOI PubMed 高影响因子
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SEPARATION AND PURIFICATION TECHNOLOGY · 2024 · IF 8.1

Effective Co2+ removal from aqueous solution and industrial wastewater using ZIF-7 and MnFe2O4-modified walnut shell biochar composite

Lei Yao,Chao Hong,Yangxu Qi,Lie Wu

In this study, we developed a novel magnetic composite of walnut shell biochar (WSB) and modified it with ZIF-7 for the purpose of removing Co 2+ ions. We conducted a comprehensive evaluation of its performance in Co 2+ removal, considering various factors such as contact time, temperature, adsorbent dose, pH, and initial Co 2+ concentration. Utilizing response surface methodology-central composite design (RSM-CCD), we examined the interactions between these variables. The specific surface area and magnetic saturation value of the WSB/MnFe 2 O 4 /ZIF-7 composite were determined as 170.560 m 2 .g −1 and 23.469 emu.g −1 , respectively. ANOVA analysis indicated that our model effectively captures the interactions between variables, with a high R 2 value of 0.9982, explaining 99.82 % of the experimental data. Optimal conditions for maximum Co 2+ adsorption efficiency (99.05 %) were identified as follows: a contact time of 44.82 min, pH of 6.04, adsorbent dose of 0.947 mg.L -1 , temperature of 25.55 °C, and Co 2+ concentration of 11.13 mg.g −1 . Kinetic studies revealed that the Pseudo 2nd order kinetic model provided the best fit to the experimental data. The negative entropy parameter indicated a decrease in disorderliness during the adsorption process, while the exothermic nature of adsorption was confirmed by enthalpy values of −92.751 and −40.511 kJ.mol −1 for WSB/MnFe 2 O 4 /ZIF-7 and WSB, respectively. Furthermore, the Langmuir isotherm model demonstrated excellent fitting to the isotherm results, suggesting the dominance of homogeneous surfaces in adsorption. The maximum adsorption capacities for Co 2+ using WSB/MnFe 2 O 4 /ZIF-7 and WSB were determined to be 29.26 and 22.39 mg.g −1 , respectively. The WSB/MnFe 2 O 4 /ZIF-7 magnetic composite demonstrates promising potential for efficiently removing Co 2+ from both natural water sources and industrial wastewater, highlighting its versatility and effectiveness in environmental remediation applications.

CAS / MDL: 51-17-2 10026-22-9
研究领域: 环境科学 · 材料科学
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