INDUSTRIAL CROPS AND PRODUCTS
·
2020
·
IF 4.244
Tao Shen,Youqin Hu,Ruijia Hu,Wei Zhuang,Ming Li,Huanqing Niu,Hong Xu,Chenjie Zhu,Hanjie Ying
The continuous production of furfural using vaporization reactor as a continuous stirred tank reactor is reported in this study. 50 g L −1 xylose solution was continuous fed into the reactor and catalyzed by 2 wt% H 2 SO 4 at 433 K gave 82.3% average yield of furfural in 10 h of reaction time. Pulp prehydrolysate derives from prehydrolysis of wood biomass was further used as the raw material for the reaction, and the 78.6% average yield of furfural was achieved for 10 h. According to Aspen Plus simulation, 11.7 tons of saturated steam was required for the production of one ton of furfural under the present reaction system, which is almost half of the traditional one-step method.
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FOOD CHEMISTRY
·
2020
·
IF 6.306
Manli Guo,Jingtian Chi,Chi Zhang,Minglin Wang,Hui Liang,Juying Hou,Shiyun Ai,Xiangyang Li
In this work, one kind of zeolite imidazole frameworks containing bovine serum albumin stabilized Au nanoclusters (AuNCs), β-galactosidase (β-Gal) and glucose oxidase (GOx) (AuNCs/β-Gal/GOx@ZIF-8) were obtained to detect lactose. Compared with other fluorescent nano-materials, AuNCs show distinct advantages as a guest species in ZIF-8, specifically their extremely small size (<1 nm), simple synthesis, excellent biocompatibility and high stability. Furthermore, the bovine serum albumin on their surfaces can promote the formation of ZIF-8 coating; thus, AuNCs were co-encapsulated in ZIF-8 with the enzymes together. X-ray diffraction (XRD) analysis indicates the composite possesses the similar crystalline structure with pure ZIF-8. Fluorescence microscope images, Fourier transform infrared spectra and energy dispersive X-ray spectroscopy indicate the presence of AuNCs in the composite. Owing to the high local concentrations of the fluorescent probe and the quenching agent in AuNCs/β-Gal/GOx@ZIF-8, the quenching rate was enhanced 3.4-fold that of free AuNCs and enzymes in solution.
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PubMed
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MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Baolei Fan,Guoliang Wei,Xiaofeng Gan,Tingting Li,Zengyi Qu,Sheng Xu,Chao Liu,Chunqi Qian
In this study, we reported the various contents of Polygonatum cyrtonema by extracting polysaccharides (PCPs) using steaming and shining procedures, thus providing scientific basis for the processing of Polygonatum cyrtonema and content analysis of polysaccharides. We established the characteristic fingerprint to identify and analyze polysaccharide component changes in distillated and processed Polygonatum cyrtonema by PMP precolumn derivatization and HPLC-MS/MS technology. We also classified two kinds of solutions by comparing the composition difference of 10 polysaccharide components in the samples with principal component and cluster analysis. There was a huge difference between them and seven monosaccharides. Processed PCPs mainly consisted of galactose along with mannose, followed by glucose. Meanwhile, we found that the results of cluster analysis and principal component analysis were the same. The polysaccharide components extracted from processed Polygonatum cyrtonema and distillate were mainly galactose and mannose. The results of cluster analysis and principal component analysis were the same. The distilled liquid can be divided into 5 categories, and the processed dry extract of Polygonatum cyrtonema can be divided into 4 categories. The changing trend of polysaccharide components of Polygonatum cyrtonema and distilled liquid was revealed during the multiple cycles of steaming and sun drying. The similarity and difference of polysaccharide components in the extracted liquid and the distilled liquid of each batch were shown.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2020
·
IF 3.232
Yi Wang,Chaoqin Han,Lan Yu,Jiangling Wu,Yuanhong Min,Juan Tan,Yannan Zhao,Pu Zhang
Numerous methods have been developed for glucose detection, only few cases can be really applied in clinical diagnosis. Herein, we report a new approach to achieve the detection of glucose in clinical samples and distinguishing the diabetic patients with healthy ones. Specifically, a fluorescence resonance energy transfer (FRET) system is established first, where nitrogen-doped carbon dots (N-CDs) and Ag nanoprisms (AgNPRs) with good spectral overlap act as energy donor and acceptor, respectively. Then, the FRET can be inhibited through oxidative etching of the energy acceptor in the presence of glucose and glucose oxidase , where hydrogen peroxide is generated to transform AgNPRs into Ag + ions. Based on the turn-on fluorescent signal versus glucose concentration, a new method for quantitative detection of glucose is developed. This etching-induced analytical method is simple, reliable, robust and cost-effective, which is promising to assist the doctors to clinically diagnose diabetes and other diseases related to metabolic disorders.
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PubMed
高影响因子
Biotechnology for Biofuels
·
2020
·Vol. 13
·期 1
·1-12
·
IF 4.815
Hua Xia,Zhou Xin,Du GenLai,Xu Yong
Background The critical issue in the competitiveness between bioengineering and chemical engineering is the products titer and the volume productivity. The most direct and effective approach usually employs high-density biocatalyst, while the weakened mass transfer and evoked foam problem accompany ultrahigh-density biocatalyst loading and substrate/product titer. In high-density obligate aerobic bioconversion, oxygen as electron acceptor is a speed-limiting step in bioprocesses, but sufficient oxygen supply will lead to the foaming which results in a significant reduction in oxygen utilization and the use of additional defoamers. In this study, we designed a novel sealed-oxygen supply (SOS) biotechnology to resolve the formidable barrier of oxygen transferring rate (OTR), for bio-based fuels and chemical production process.Results Based on systemic analysis of whole-cell catalysis in Gluconobacter oxydans, a novel sealed-oxygen supply technology was smartly designed and experimentally performed for biocatalytic oxidation of alcohols, sugars and so on. By a simple operation skill of automatic online supply of oxygen in a sealed stirring tank bioreactor of SOS, OTR barrier and foaming problem was resolved with great ease. We finally obtained ultrahigh-titer products of xylonic acid (XA), 3-hydroxypropionic acid (3-HPA), and erythrulose at 588.4 g/L, 69.4 g/L, and 364.7 g/L, respectively. Moreover, the volume productivity of three chemical products was improved by 150–250% compared with normal biotechnology. This SOS technology provides a promising approach to promote bioengineering competitiveness and advantages over chemical engineering.Conclusion SOS technology was demonstrated as an economic and universally applicable approach to bio-based fuels and chemicals production by whole-cell catalysis. The novel technology greatly promotes the competitiveness of bioengineering for chemical engineering, and provides a promising platform for the green and environmental use of biofuels.
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Sustainable Energy & Fuels
·
2019
·Vol. 4
·期 3
·1383-1395
·
IF 4.912
Mengmeng Wang,Lincai Peng,Xueying Gao,Liang He,Junhua Zhang
An integrated catalytic protocol involving dehydration, transfer-hydrogenation and alcoholysis towards one-pot conversion of xylose to alkyl levulinate was invented using a combination of Zr(20)-MCM-41 and H3O40PW12 catalysts. Secondary alcohols like 2-propanol and 2-butanol as the reaction medium exhibit equally superior hydrogen donating capability, but the dehydration step of xylose in 2-butanol is preferred probably due to its stronger hydrophobicity. A good alkyl levulinate yield of 53% can be achieved under optimized conditions. The spent dual catalysts can be effectively recovered and they exhibit good reusability after thermal regeneration of Zr(20)-MCM-41. Research on the catalytic mechanism shows that well-dispersed ZrO2 supported on MCM-41 is responsible for the catalytic transfer hydrogenation step of furfural to furfuryl alcohol. Proper tuning of the Lewis and Brønsted acidities can efficiently promote the acid-driven reaction steps of xylose conversion and simultaneously inhibit the alkyl levulinate-to-γ-valerolactone side reaction. The sustainability of this conversion is greatly improved by process intensification based on the new catalytic strategy and mild reaction conditions.
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RSC Advances
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2019
·Vol. 9
·期 52
·30144-30153
·
IF 3.049
Yu Han,Huili Hao,Lihong Yang,Guolian Chen,Yucong Wen,Riming Huang
Sardinella zunasi Bleeker, an edible and medicinal marine fish, is largely distributed in tropical oceans. However, the chemical composition and nutritional properties of this species have not yet been investigated. In the present study, proximate composition, fatty acids, amino acids, taurine, and minerals of S. zunasi Bleeker were characterized, and the immunostimulatory properties of its glycoprotein were evaluated. The results indicated the presence of crude protein (19.66%), crude lipid (6.29%) and carbohydrate (0.74%) in S. zunasi Bleeker; monounsaturated fatty acids and polyunsaturated fatty acids in the fatty acid composition of S. zunasi Bleeker were 25.00% and 31.01%, respectively; S. zunasi Bleeker was rich in taurine (219 mg/100 g) and essential amino acids (5.57 g/100 g). In addition, the glycoprotein of S. zunasi consisted of protein and sugars, with a total content of 34.25% and 16.27%, respectively. The glycoprotein showed significant effects on promoting NO, TNF-α and IL-6 in a dose-dependent manner in RAW264.7 macrophage cells. Thus, these findings provide a scientific basis for the further utilization of glycoprotein from S. zunasi Bleeker.
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Journal of Energy Chemistry
·
2022
·
IF 13.599
Fuyan Kang,Cai Shi,Yeling Zhu,Malin Eqi,Junming Shi,Min Teng,Zhanhua Huang,Chuanling Si,Feng Jiang,Jinguang Hu
The global commitment to pivoting to sustainable energy and products calls for technology development to utilize solar energy for hydrogen (H 2 ) and value-added chemicals production by biomass photoreforming. Herein, a novel dual-functional marigold-like Zn x Cd 1 -x S homojunction has been the production of lactic acid with high-yield and H 2 with high-efficiency by selective glucose photoreforming. The optimized Zn 0.3 Cd 0.7 S exhibits outstanding H 2 generation (13.64 mmol h −1 g −1 ), glucose conversion (96.40%), and lactic acid yield (76.80%), over 272.80 and 19.21 times higher than that of bare ZnS (0.05 mmol h −1 g −1 ) and CdS (0.71 mmol h −1 g −1 ) in H 2 generation, respectively. The marigold-like morphology provides abundant active sites and sufficient substrates accessibility for the photocatalyst, while the specific role of the homojunction formed by hexagonal wurtzite (WZ) and cubic zinc blende (ZB) in photoreforming biomass has been demonstrated by density functional theory (DFT) calculations. Glucose is converted to lactic acid on the WZ surface of Zn 0.3 Cd 0.7 S via the photoactive species O 2 − , while the H 2 is evolved from protons (H + ) in H 2 O on the ZB surface of Zn 0.3 Cd 0.7 S. This work paves a promising road for the production of sustainable energy and products by integrating photocatalysis and biorefine.
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Sustainable Chemistry and Pharmacy
·
2022
·
IF 5.464
Yalan Zhang,Liang He,Qin Li,Junwen Cheng,Yanbin Wang,Jiancheng Zhao,Shaofei Yuan,Yongjian Chen,Rui Shi
To the valorization of Indocalamus tessellatus（I.tessellatus） leaves for the functional food industry, the process of ultrasonic-assisted deep eutectic solvent (DES) extraction of I.tessellatus leaves polysaccharides (U-DES-ICP) was optimized by response surface methodology . In comparison to ultrasonic extracted polysaccharides (UICP) and water extracted polysaccharides (WICP), their physicochemical properties were analyzed by HPLC , HPGPC-MALLS, and FTIR, and the structure morphology was observed by SEM . Their antioxidant activities were evaluated based on DPPH and ABTS + assay as well. The results showed that the best DES system for U-DES-ICP was a mixture of choline chloride and malonic acid in the molar ratio of 1:4 (10% water content). The highest yield of U-DES-ICP (0.6812%) was obtained by following optimized conditions: 60 min of sonication time, 17 mL/g of liquid-solid ratio, 500W of sonication power, and 63.5 °C of sonication temperature, which was significantly higher than that of the conventional methods. The structural analysis indicated that U-DES-ICP had more uronic acid with higher molecular weight compared with UICP and WICP, the relative content of uronic acid of U-DES-ICP reached 8.364%, which was twice as much as the other two polysaccharides; its molecular weight reached up to 6.201 × 10 3 KD, and the highest values of molecular weight of UICP and WICP were 1.684 × 10 3 KD and 995.4 KD, U-DES-ICP which were confirmed by SEM . The antioxidant assays reflected that U-DES-ICP possessed stronger scavenging capacities both on DPPH and ABTS + radicals with IC50 (0.48 mg/mL and 0.61 mg/mL) than the other two biomacromolecules. IC50s for DPPH and ABTS radical scavenging by UICP were 0.51 and 0.73 mg/mL, while 0.82 and 0.94 mg/mL were IC50s for both radical scavenging by WICP, respectively. Therefore, this study evidenced that a novel DES system could boost the extraction of I.tessellatus leaves polysaccharides, which produced a higher yield of product with stronger biological activities compared with traditional techniques.
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ACS Catalysis
·
2022
·
IF 13.7
Weipeng Song,Huai Liu,Junhua Zhang,Yong Sun,Lincai Peng
Furfural represents one of the most valuable biomass-derived platform molecules. Its selective production with a smart and tractable catalytic system is highly attractive for technical implementation, yet remains challenging. We herein report a promising protocol involving the mature Hβ zeolites in pure 1,4-dioxane to convert hemicellulose-related sugars into furfural with high rate and impressive selectivity under mild operating conditions. Furfural yields as high as 93.6% (from xylose) and 85.9% (from xylan) were accomplished at 140 °C in 40 min. The solvent 1,4-dioxane served as a shield to maintain the crystal structure and acidic center of Hβ as well as to inhibit the polymerization of furfural. The synergistic action of Hβ with 1,4-dioxane largely promoted the selective conversion of xylose to furfural, as the multiple immobilized acid sites of Hβ in 1,4-dioxane medium accelerated xylose-to-xylulose isomerization. The dehydration process was favorable based on its apparent activation energy of 39.1 kJ mol–1, leading to a high turnover frequency of 53.8 h–1. Density functional theory calculations revealed that the superior catalytic behavior could be ascribed to the higher adsorption of xylose than 1,4-dioxane, allowing xylose molecules to fully access the open Al sites of Hβ and the low Gibbs free energy barrier of xylose isomerization to xylulose in 1,4-dioxane over the Hβ catalyst. Moreover, the heterogeneous zeolite catalyst and the single low-boiling-point solvent 1,4-dioxane (101 °C) were readily recovered from the product with outstanding reusability. This contribution not only opens a high potential avenue for the selective production of furfural but also sheds light on the coordination mechanism of Hβ zeolite and 1,4-dioxane toward developing tailored processes.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Yuchao Shao,Weizhong Huo,Rong Ye,Yanqing Liu,Muhammad Ajmal,Wenjing Lu
The humification behavior of lignocellulosic components ( i.e. , cellulose, hemicellulose and lignin) under acid-alkali two-step hydrothermal treatment was investigated with particular interest of revealing the contribution of single components as well as their interaction to hydrothermal humic acid (HHA). Lignin with its rich aromatic structures, had the highest HHA contribution (51.8 ± 1.0 wt%), while cellulose and hemicellulose only contributed 8.8 ± 1.6 wt% and 20.1 ± 4.4 wt% HHA yields, respectively. The conversion pathway of these components toward humification indicated that the hydrochar (HC) rather than the hydrothermal solution (HS) had higher humification capability under alkaline hydrothermal conditions because the hydrochar-derived HHA yields of 40.8 ± 2.0 wt% (cellulose), 66.2 ± 6.4 wt% (hemicellulose) and 55.4 ± 6.1 wt% (lignin) were achieved. In addition, co-hydrothermal treatment of cellulose, hemicellulose and lignin under this process improved the HHA production ascribing to the increased HC yield (23.1–53.1 %). The chemical characteristics of HHA products from lignocellulosic components (cellulose, hemicellulose, lignin) and their combinations were similar to the acknowledged natural humic acids. The hydrothermal humification of biowaste mainly passes through a top-down pathway ( i.e. , HHA forms from the oxidation of large fragments of hydrochar) as well as two bottom-up pathways ( i.e. , the soluble chemicals conduct the polymerization reaction for HHA production and react with the fragments from HC to synthesize the HHA). This study filled the lack of knowledge in the field of biowaste humification.
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GREEN CHEMISTRY
·
2022
·Vol. 24
·期 22
·8812-8819
·
IF 11.034
Qiyu Liu,Liang Zhou,Xinyi Xie,Di Fan,Xinping Ouyang,Wei Fan,Xueqing Qiu
Selective production of glucose from cellulose in a molten salt hydrate (MSH) shows high efficiency but the separation of glucose is still challenging. To address this issue, we proposed a stepwise method, where cellulose was first hydrolyzed into glucan oligomers and separated via anti-solvent precipitation, followed by being hydrolyzed into glucose under mild conditions. For potential industrial applications, using raw biomass as a substrate is more attractive due to its commercial advantages. However, directly hydrolyzing raw corn stover in an MSH resulted in a low glucan oligomer yield and sugar concentration, together with insufficient separation efficiency. This work demonstrated that the generation of acetic acid during hemicellulose hydrolysis is the critical factor affecting glucan oligomer selectivity. To address this issue, a pre-extraction method using auto-hydrolysis was proposed to remove hemicellulose before MSH hydrolysis. After pre-extraction, the obtained glucan oligomer yield could be enhanced from 59.9% to 79.5%, with the separation efficiency increased from 53.7% to 80.6% by methanol precipitation. Besides, increasing the raw corn stover concentration led to an increase in acetic acid and resulted in glucan oligomer degradation. However, after removing hemicellulose, the concentration of glucan oligomers could be significantly enhanced from less than 72.1 to 121.5 mg mL−1. Thus, pre-extraction of hemicellulose followed by MSH hydrolysis provides a potential application for directly producing glucan oligomers from raw biomass with improved yield and separation efficiency.
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