TALANTA
·
2016
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IF 4.035
Houmei Liu,Jia Chen,Zhan Li,Makoto Takafuji,Hirotaka Ihara,Hongdeng Qiu
In this work, a “solvent-free” and green method for controllable and quantitative preparation of chromatographic stationary phase has been proposed. About the method, the largely excess of functional monomer and strict control of the proportion between silane and silica are the two most important points. Due to the existence of excessive functional monomer, silane can be utilized at the maximum extent, thereby achieving quantitative and reproducible bonding. Meanwhile, the excessive monomer can also be well recycled. By this new method, we controllably synthesized three Sil-MIm columns with various bonding amounts to investigate how the bonding amounts influence separation performances. The experiment results stated in some cases the columns with appropriate bonding amounts rather than maximum, were the best to fulfil some specific tasks. Meanwhile, it also demonstrated how important it was to control the bonding amounts of stationary phase.
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高影响因子
CHEMICAL PAPERS
·
2017
·Vol. 69
·期 2
·262-268
·
IF 1.258
Cai Long-Fei,Zhong Ming-Hua,Chen Wen-Yin,Xu Chun-Xiu,Wu Yun-Ying
A method was developed for the fabrication of microfluidic paper-based analytical devices (μPAD). This method was based on the silanisation of cellulose in filter paper using alkyltrimethoxysilane coupled with UV radiation. The filter paper sheet was hydrophobised by immersion in an octadecyltrimethoxysilane/heptane (OTMS/heptane) solution (0.25 vol. %) containing 5 vol. % of ethyl acetate (EtOAc). The hydrophobic-hydrophilic contrast was generated on the filter paper after the hydrophobised paper sheet was exposed to UV light with a metal mask creating the desired pattern on the sheet. The exposed area was oxidised to create a hydrophilic area, while the hydrophobic area was protected by the metal mask. The optimal conditions for the fabrication of μPAD were studied; these included ethyl acetate concentration ( C EtOAc ), immersion time, octadecyltrimethoxysilane concentration ( C OTMS ) and exposure time. This method is cost-effective and simple. In addition, different functional groups could be further grafted for various assay purposes. To demonstrate the feasibility of the μPAD in analytical applications, a flower-shaped μPAD with eight channels and eight detection units was fabricated and used to determine the nitrite content in pickled vegetables. The nitrite content (124 µg g −1 ) in the sample determined by this method compared favourably with that measured using a standard method (137 µg g −1 ).
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Small
·
2024
·
IF 13
Min Yan,Ranran Wei,Ruifan Zhang,Xiaoying Zhang,Shiqin Sun,Xuewen Wei,Xianlong Wang,Shuli Yin,Yinglong Wang
Electrochemical nitrite reduction reaction ( NO 2 − RR ${\mathrm{NO}}_{\mathrm{2}}^{\mathrm{ - }}{\mathrm{RR}}$ ), as a green and sustainable ammonia synthesis technology, has broad application prospects and environmental friendliness. Herein, an unconventional p - d orbital hybridization strategy is reported to realize the fabrication of defect-rich CuSb porous nanonetwork (CuSb PNs) electrocatalyst for NO 2 − RR ${\mathrm{NO}}_{\mathrm{2}}^ - {\mathrm{RR}}$ . The crystalline/amorphous heterophase structure is cleverly introduced into the porous nanonetworks, and this defect-rich structure exposes more atoms and activated boundaries. CuSb PNs exhibit a large NH 3 yield ( r N H 3 ${{r}_{{\mathrm{N}}{{{\mathrm{H}}}_{\mathrm{3}}}}}$ ) of 946.1 µg h −1 m cat − 1 ${\mathrm{m}}_{{\mathrm{cat}}}^{ - {\mathrm{1}}}$ and a high faradaic efficiency (FE) of 90.7%. Experimental and theoretical studies indicate that the excellent performance of CuSb PNs results from the defect-rich porous nanonetworks structure and the p-d hybridization of Cu and Sb elements. This work describes a powerful pathway for the fabrication of p - d orbital hybrid defect-rich porous nanonetworks catalysts, and provides hope for solving the problem of nitrogen oxide pollution in the field of environment and energy.
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JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Wuxia Ge,Yumei Chen,Xinru Ding,Wentao Bi,David Da Yong Chen
Magnetic aromatic polyamide (MAPA) composites were synthesized using a green mechanochemical ball milling process and used for magnetic solid-phase extraction (MSPE) and detection of trace level fluoroquinolone antibiotics (FQs) from water samples. The formation of MAPAs was facilitated by deep eutectic systems (DESys) created from magnetic beads and organic monomers during ball milling. A comprehensive study was conducted to investigate the kinetics, thermodynamics, and mechanisms of MAPA adsorption of ciprofloxacin hydrochloride (CIP) and ofloxacin (OFL) from water. The maximum adsorption capacities for CIP and OFL were found to be 151.5 mg/g and 164.1 mg/g, respectively. Additionally, the recyclability and selective adsorption capabilities of MAPAs were evaluated. MAPAs were subsequently used for MSPE of CIP and OFL in water samples. Both UV–Vis spectrometry and HPLC methods can be used for analysis, the MSPE-HPLC method showed superior linearity for CIP (0.06–1500 μg/L) and OFL (1–1200 μg/L), with R² values of 0.9995 and 0.9999, and limit of detection (LOD) as low as 0.006 μg/L and 0.02 μg/L, respectively. Both analytical methods are highly effective and practical for use with real water samples. MAPA used for MSPE offer a promising green approach for detecting antibiotic contamination in aquatic ecosystems.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Shang-Xiong Wei,Yu-Hang Yang,Xue-Bo Liu,Xiao-Bin Ye,Xiao-Peng Zhao,Xue-Wei Pi,Xue-Feng Cheng,Jing-Hui He
The electrochemical reduction reaction of nitrate (NO 3 RR) to ammonia is an environmentally friendly approach that can treat wastewater as well as find an alternative to the energy-intensive Haber-Bosch process. The use of adhesives partially to adhere to the NO 3 RR electrocatalysts, leading to sluggish kinetics, poor stability and poor scalability. Herein, we report the synthesis of PdCu alloy catalysts via a direct laser writing method, demonstrating their exceptional performance in the electrochemical reduction of nitrate. The Pd 0.55 Cu 0.45 alloy exhibited a remarkable ammonia production rate of 30.55 mg h −1 cm −2 under neutral electrolyte conditions and maintained stable operation for over 1500 h. Density functional theory (DFT) calculations and experimental analyses revealed that the PdCu alloy’s enhanced activity stems from its lower energy barrier for the rate-determining step (*NO → *NOH) and improved mass transfer capabilities. The alloy’s electronic properties and geometric configuration, fine-tuned by the laser-induced synthesis method, facilitate the conversion of NO 2 − and suppress the hydrogen evolution reaction (HER), thereby significantly enhancing the selectivity and activity of the NO 3 RR process. This study provides a sustainable and efficient pathway for ammonia synthesis and offers insights into the design of advanced catalysts for environmental and energy applications.
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FOOD CHEMISTRY
·
2018
·
IF 4.946
Qisen Xiang,Xiufang Liu,Junguang Li,Shengnan Liu,Hua Zhang,Yanhong Bai
This work aimed to evaluate the effects of dielectric barrier discharge (DBD) plasma on inactivation of spoilage yeast Zygosaccharomyces rouxii ( Z. rouxii ), in apple juice. Results showed that DBD plasma treatment at 90 W for 140 s resulted in about 5-log reduction of Z. rouxii in apple juice. The levels of extracellular nucleic acids and proteins as well as contents of H 2 O 2 and NO 2 − in yeast extract-peptone-dextrose (YPD) medium increased significantly after DBD plasma treatment at 90 W for 40–200 s. The increases in membrane permeability and generation of reactive species would likely contribute to DBD plasma-mediated inactivation of Z. rouxii . DBD plasma caused significant changes in pH, titratable acidity, and certain color parameters of apple juice, but had no effect on the contents of total soluble solids, reducing sugar, and total phenolics. This study provides key implications for the application of DBD plasma in fruit juice processing.
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Journal of Energy Chemistry
·
2024
·
IF 14
Yinuo Wang,Yian Wang,Qinglan Zhao,Hongming Xu,Shangqian Zhu,Fei Yang,Ernest P. Delmo,Xiaoyi Qiu,Chi Song,Juhee Jang,Tiehuai Li,Ping Gao,M. Danny Gu,Minhua Shao
Urea generation through electrochemical CO 2 and NO 3 − co-reduction reaction (CO 2 NO 3 RR) is still limited by either the low selectivity or yield rate of urea. Herein, we report copper carbonate hydroxide (Cu 2 (OH) 2 CO 3 ) as an efficient CO 2 NO 3 RR electrocatalyst with an impressive urea Faradaic efficiency of 45.2% ± 2.1% and a high yield rate of 1564.5 ± 145.2 μg h −1 mg cat −1 . More importantly, H 2 evolution is fully inhibited on this electrocatalyst over a wide potential range between −0.3 and −0.8 V versus reversible hydrogen electrode. Our thermodynamic simulation reveals that the first C-N coupling follows a unique pathway on Cu 2 (OH) 2 CO 3 by combining the two intermediates, *COOH and *NHO. This work demonstrates that high selectivity and yield rate of urea can be simultaneously achieved on simple Cu-based electrocatalysts in CO 2 NO 3 RR, and provide guidance for rational design of more advanced catalysts.
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ACS Nano
·
2025
·
IF 16
Ning He,Zhi Yuan,Chao Wu,Shibo Xi,Jingjing Xiong,Yucong Huang,Guanwu Lian,Zefan Du,Laihao Liu,Dawei Wu,Zhongxin Chen,Wenguang Tu,Zhigang Zou,Shuk-Yin Tong
Electrochemical nitrate reduction (NO3RR) to ammonia presents a promising alternative strategy to the traditional Haber–Bosch process. However, the competitive hydrogen evolution reaction (HER) reduces the Faradaic efficiency toward ammonia, while the oxygen evolution reaction (OER) increases the energy consumption. This study designs IrCu4 alloy nanoparticles as a bifunctional catalyst to achieve efficient NO3RR and OER while suppressing the unwanted HER. This is achieved by operating the NO3RR at positive potentials using the IrCu4 catalyst, which allows a Faradaic efficiency of 93.6% for NO3RR. When applied to OER catalysis, the IrCu4 alloy also shows excellent results, with a relatively low overpotential of 260 mV at 10 mA cm–2. Stable ammonia production can be achieved for 50 h in a 16 cm2 flow electrolyzer in simulated working conditions. Our research provides a pathway for optimizing NO3RR through bifunctional catalysts in a tandem approach.
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高影响因子
CHEMICO-BIOLOGICAL INTERACTIONS
·
2024
·
IF 4.7
Changfeng Zhong,Changmei Wang,Wei Li,Wenyuan Li,Xuemei Chen,Jieqing Guo,Yifan Feng,Xia Wu
Parkinson's disease (PD) is the fastest growing neurodegenerative disease in the world at present. Neuroinflammation plays an important role in Parkinson's disease. In our study, we initially screened magnolol/honokiol derivatives synthesized by our group for their potential anti-neuroinflammatory properties. This was done using LPS-activated BV-2 microglial cell and MPP + -induced PC-12 cell models. Most of derivatives had increased anti-inflammatory activities and decreased toxicities compared to raw materials. Then, compounds were scored with inflammatory factors IL-1β, TNF-α and IL-6 by molecular docking in silico . Our studies revealed the strongest binding compound HM568 which binds with honokiol and metformin. Furthermore, HM568 showed no acute toxicity in mice through acute toxicity. And it is stable under high temperature, high humidity and strong light irradiation. Combining cell experiments and computer results, HM568 was considered for further in vivo pharmacological validations. Intraperitoneal injection administration of MPTP into C57BL/6 mice was utilized as Parkinson's animal model. Results showed that administration of HM568 for 14 days in MPTP-PD mice led to a significant alleviation in weight loss and movement disorders. Further HM568 could significantly down-regulate the expression levels of inflammatory factors IL-1β, IL-6 and TNF-α in brain tissue of the mouse model, reduce the level of caspase-3 and the ratio of Bcl-2/Bax, and up-regulate the level of transforming factor TGF-β, thus producing anti-apoptosis and anti-neuroinflammatory effects on neuronal cells. In terms of pathological features, HM568 could reduce the infiltration of neuronal cells and alleviate the development of lesions, promote the transformation of microglia from M1 negative phenotype to M2 type, and reverse the reduction of TH-positive immune cells in mouse neurons induced by MPTP. The administration of HM568 could reduce the abnormal accumulation of α-syn, and thus produce neuroprotective effect on MPTP-PD mice. Cell experiments, molecular docking and animal experiments thus depict HM568 as a promising agent to delay neuronal degeneration in PD, and its mechanism is related to anti-neuroinflammation.
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Journal of Materials Chemistry A
·
2025
·
IF 9.5
Ru Jia,Xiaoxue Zhang,Li Gan,Muhammad Tahir,Zhen-Feng Huang,Lun Pan,Ruijie Gao,Chengxiang Shi,Xiangwen Zhang,Guidong Yang,Ji-Jun Zou
The nitrate reduction reaction (NO3RR) represents a promising route for water treatment and NH3 generation. This process involves the deoxygenation of NO3− to form nitrite (NO2−), followed by its subsequent hydrogenation. However, discrepancies in the rates of these two steps result in a decrease in faradaic efficiency (FE) and NH3 yield rate. Herein, we demonstrated a tandem catalyst of (Cu7/Ag3)7-Ru3/C achieving a high NH3 yield rate of 3.45 mmol h−1 cm−2 (2.30 mol gcat−1 h−1) and a FE of 93.48% at −0.9 V vs. the reversible hydrogen electrode. The Cu/Ag heterostructure greatly enhanced the conversion of NO3− to NO2− over a wide potential window due to the synergistic effect, while Ru, selectively adsorbing NO2−, provided active hydrogen derived from water hydrolysis to facilitate NH3 synthesis. Furthermore, (Cu7/Ag3)7-Ru3/C exhibited stable performance in a membrane electrode assembly over 60 hours, achieving an average NH3 yield rate of 6.90 mmol h−1. The ammonium chloride solid product was successfully obtained using an air stripping methodology. In situ characterization revealed that the surface microenvironment of Ru influenced the adsorption configuration of *NO and on-top adsorbed NO was more favorable for ammonia synthesis compared to bridge-adsorbed NO. The overall reaction pathway involved stepwise deoxygenation to form *N and subsequent gradual hydrogenation.
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MEASUREMENT
·
2025
·
IF 5.6
Jintao Liang,Zhenshun Wei,Qing Huang,Jianlu Liang,XiuChuan Zhao,Zhide Zhou,Guiyin Li
Tea polyphenols are a general term for the total phenolic compounds in tea. Tea polyphenols play a crucial role in the quality of tea. Rapid detection of tea polyphenols is essential for tea harvesting and breeding. In this paper, a rapid method for the detection of tea polyphenols is presented based on diazotization coupling (DC) reaction and flow batch analysis system (FBAS). The tea polyphenols detection based on DC reaction can avoid interference from non-phenolic substances and improve detection accuracy. Meanwhile, FBAS for sample injection can shorten the analysis time, reduce the reagent consumption and improve the sensitivity. Experimental results demonstrate that absorbance values exhibit linearity with gallic acid concentrations in the range of 5 to 60 μg/mL, with a linear equation of y = 0.0279x + 0.0613 (R 2 = 0.9993) and a limit of detection (LOD) of 0.215 μg/mL (S/N=3). The method was applied to the detection of tea polyphenols in tea samples, with relative standard deviations (RSD) ranging from 0.326% to 0.659%. The DC-FBAS method has a high potential application with the requirements of portable, cost-effective, and highly precise on-site tea polyphenols detection.
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ACS Catalysis
·
2025
·
IF 13.1
Jieying Wan,Ji Yang,Na Yang,Yifei Sun,Chuansheng Hu,Yang Zhao,Xiaoyan Xu,Haifeng Qi,Xiaodong Li,Hao Zhang
Electrochemical nitrate reduction reaction (NO3–RR) presents a sustainable method for ammonia synthesis. Single-atom catalysts possessing the symmetric planar four-ligand structure (M-N4) serve as advantageous catalytic active sites for NO3–RR. However, the inherent extreme symmetry of the standard M-N4 structure limits the reaction kinetics. Herein, we introduce a symmetry-breaking iron single-atom catalyst coordinated with axial chlorine on nitrogen-doped carbon (Cl-Fe-NC) for NO3–RR. Cl-Fe-NC exhibits a 99.4% ammonia Faradaic efficiency (FE) at −0.28 V vs reversible hydrogen electrode (RHE) with a 9396.7 μgNH3 h–1 cm–2 yield rate at −0.68 V vs RHE, remarkably surpassing that of Fe-NC (<80%, 4330.9 μgNH3 h–1 cm–2 at the same potential). Operando synchrotron radiation Fourier transform infrared (SR-FTIR) spectroscopy confirms that key intermediates, such as *NO, *NO-Hx, and σ(N–H), are formed. Density functional theory (DFT) calculations attribute the optimized free energy of NO3–RR intermediates to the axial chlorine design, reducing the potential determination step barrier energy by up to 0.66 eV. The presence of axial Cl atoms modulates the symmetry of the single Fe atom, enhancing the adsorption of nitrate ions and the enrichment of critical intermediates during NO3–RR while inhibiting the hydrogen evolution reaction (HER). This discovery opens avenues for boosting electrochemical ammonia synthesis through the precise modulation of atomic structures by doping heteroatoms for symmetry breaking.
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