INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Tong Luo,Xiaoliang Guo,Ji Qi,Juan Yu,Chuanwei Lu,Chunpeng Wang,Fuxiang Chu,Jifu Wang
Recently, the utilization of the cellulose to fabricate the multifunctional materials with aim to replace the petroleum-based product, is receiving significant attentions. However, the development of cellulose-based multifunctional materials with high mechanical strength and temperature resistance is still a challenge. Herein, the intrinsic feature and property of cellulose and rosin were creatively employed to fabricate a novel cellulose-rosin based poly(esterimide) (PEI) by esterification reaction and imidization reaction, and the obtained cellulose-rosin derived PEI exhibits superior thermal stability. Then the as-prepared cellulose-rosin derived PEI was dissolved in polymerizable deep eutectic solvents (PDES) and in-situ formed the ionic conductive elastomer (ICE) with via UV-induced polymerization. These cellulose-rosin based ICE exhibited excellent mechanical properties, solvent resistance, and temperature tolerance. By adjusting the mass ratio of cellulose-rosin derived PEI and PDES, the as-prepared liquid-free ICE functions as UV shadowless adhesive and wearable sensors. The bonding strength of UV shadowless adhesive could 1.52 MPa, which could be applied to fix the broken glass toy models. Furthermore, wearable sensors based those ICE could monitor the large and subtle movements even under extreme environmental condition, such as being soaked in organic solvent (such as tetrahydrofuran) or at low/high temperature (−25 °C or 80 °C). This work opens a new avenue for the next-generation of multifunctional ICE.
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ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Tong Luo,Ji Qi,Juan Yu,Chunpeng Wang,Fuxiang Chu,Jifu Wang
Hydrophobic conductive gels have attracted much attention in underwater sensing as the soft robots and wearable sensors. Among the various methods for preparing conductive gels, UV-initiated polymerization shows advantages of rapid curing and significant energy savings. However, traditional commonly used photoinitiators in UV-initiated polymerization often migrate or diffuse within conductive gels, especially with prolonged use or underwater, posing potential environmental and health risks. Herein, a novel lignin-based macromolecular photoinitiator (L-BF) is first designed by incorporating benzoylformate into the lignin backbone, demonstrating excellent UV absorption, high radical initiation efficiency, and hydrophobicity. Subsequently, hydrophobic eutectogels (HEG) are prepared via UV-initiated polymerization using L-BF as photoinitiator. The HEG shows excellent mechanical properties (toughness of 5.67 MJ m − 3 and strain of 941%) and scarcely L-BF migration underwater. Moreover, the hydrophobic network of L-BF endowed HEG with hydrophobicity (water contact angle exceeds 110°; swelling ratio is <5.8%), superior underwater adhesion (255 kPa), even maintained excellent sensing performance (gauge factor of 4.69), and long-term reproducibility (20 000 cycles) in air and underwater. Validation confirms the potential of HEG as an effective wearable sensor for underwater posture monitoring and communication, advancing the use of lignin and low-migration conductive gels in marine exploration.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Sibei Wang,Fan Nie,Zhen Lin,Jing Xu,Yuanqiang Guo
Cancer poses a significant medical challenge worldwide. Research into tumor biology has revealed the prevalence of acidic conditions and abnormally high levels of reactive oxygen species (ROS) within the tumor microenvironment. In response to these findings, a ROS-responsive crosslinker, (((oxalylbis(oxy))bis(methylene))bis(4,1-phenylene))diboronic acid (OBA), was designed and synthesized using (4-hydroxymethyl)phenylboronic acid and ethanedioyl chloride as reactants. pH-responsive boronate ester bonds were formed between the diboronic acid groups of the crosslinker and the dihydroxyl groups of the naturally occurring active Astragalus polysaccharide (ASP). This resulted in the successful construction of pH/ROS dual-responsive nanogels (BAI@ASPOBA) loaded with the chemotherapeutic natural small molecule baicalein (BAI). Characterization of BAI@ASPOBA through molecular dynamics simulations and other methods demonstrated that it not only inhibited the proliferation of A549 tumor cells in vitro but also exhibited remarkable anti-tumor activity in vivo , along with excellent safety and biocompatibility. Further mechanistic studies revealed that the anti-tumor activity arises from the synergistic enhancement of the chemotherapeutic effects of BAI and the natural polysaccharide ASP. Specifically, the constructed BAI@ASPOBA nanogels enhanced the anti-tumor efficacy of BAI, while ASP, serving as the carrier for the nanomaterials, played an immunostimulatory role, facilitating tumor immunotherapy. The design and development of the novel BAI@ASPOBA nanogels in this study are anticipated to provide a new and effective treatment strategy for cancer therapy.
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CARBOHYDRATE POLYMERS
·
2018
·
IF 5.158
Chuanwei Lu,Juan Yu,Chunpeng Wang,Jifu Wang,Fuxiang Chu
Cellulose-rosin based thermoplastic elastomers with UV absorption properties were fabricated by a combination of rosin, poly(butyl acrylate) (PBA) and ethyl cellulose (EC) via “graft from” ATRP with the aid of EC-rosin macroinitiator (EC- g -(DA)-Br) prepared by a simple esterification reaction between EC, dehydroabietic acid (DA, one of rosin’s resin acids) and 2-bromoisobutylryl bromide. The introduction of rosin affords these elastomers with UV absorption property. And the glass transition temperature of these EC-rosin grafted copolymers could be tuned by changing the content of PBA. Moreover, the introduction of PBA to EC endowed EC- g -(DA)- g -PBA with a good film-forming property and excellent thermoplastic elastomer behavior. All of these EC-rosin grafted copolymers showed an excellent UV absorption performance, and maintained outstanding UV absorption capability after continuous UV-irradiation or being heated to 115 °C for 1 h. As a result, these EC-rosin grafted copolymers have a potential application in coating materials with UV absorption property.
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JOURNAL OF MEMBRANE SCIENCE
·
2018
·
IF 6.578
Qian Yang,Chen Xiao Lin,Fang Hua Liu,Ling Li,Qiu Gen Zhang,Ai Mei Zhu,Qing Lin Liu
To improve the overall performance of anion exchange membranes (AEMs) for fuel cells, a series of composite AEMs was prepared via a facile approach using ionic liquid-functionalized graphene oxide (IL-GO) and imidazolium-functionalized poly (2,6-dimethyl-1,4-phenylene oxide) (ImPPO). The prepared ImPPO/IL-GO-0.5% (0.5% refers to the weight percentage of IL-GO) membranes with an ionic exchange capacity (IEC) of 1.9 meq g −1 achieved a hydroxide conductivity of 78.5 mS cm −1 . The high conductivity of ImPPO/IL-GO-0.5% is due to the fact that the ionic cluster size of composite membranes (3.43–3.58 nm) is larger than that of the pristine membrane (3.30 nm). The ionic cluster morphology is confirmed by atomic force microscopy (AFM) and small angle X-ray scattering (SAXS). Moreover, the AEMs retained approximately 70% of their initial hydroxide conductivity after the alkaline stability test in a 2 M aqueous NaOH at 80 °C for 480 h, indicating a good alkaline stability. A single cell using ImPPO/IL-GO-0.5% exhibits a peak power density of 136 mW cm −2 at 60 °C under 100% related humidity, thereby having a great potential for fuel cells.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Lirong Liao,Zhijun Ke,Shuchun Li,Sijie Wang,Xinyang Wang,Xiaoping Rao
This study focuses on enhancing the antibacterial and self-cleaning properties of bio-based food packaging films. We developed a zwitterionic rosin sulfonated betaine (MPA-BN + SO 3 − ) and co-grafted it with rosin quaternary ammonium salt onto chitosan, which was then combined with gelatin to create the films. Characterization was done using FTIR and 1 H NMR. The films exhibited a minimum inhibitory concentration (MIC) of 200 μg/mL for Staphylococcus aureus and 400 μg/mL for Escherichia coli , with a 19 mm antibacterial zone for 30% CS-B-S in Staphylococcus aureus . The modification improved water solubility, tensile strength (10.22 MPa, a 20% increase), elongation at break (87%), and antioxidant properties (48.2%). Preservation tests on fresh fruits and biological safety assessments through cytotoxicity tests and a 30-day gastric lavage experiment in mice confirmed the effectiveness and safety of films. Outdoor degradation tests showed strong biodegradability and minimal environmental impact. These results suggest that the CS-B-S/gelatin film is a promising food packaging material with excellent antibacterial, antifouling, and biodegradable properties.
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LANGMUIR
·
2024
·
IF 3.7
Yueji Li,Yuteng Zhang,Xue Liu,Bin Dong,Pan Xu,Bo Song
Heparin is widely used to treat thrombosis because it is an effective anticoagulant. However, excessive use of heparin can lead to an increased risk of bleeding, which makes the quantitative detection of heparin very important. An amphiphilic perylene bisimide molecule (denoted PBI-9) was developed, which presented a near-infrared emission peak at 730 nm when it was aggregated. PBI-9 has been utilized in the detection of heparin, as the pyridine cation in PBI-9 binds strongly to highly sulfated heparin through electrostatic interactions. Charge neutralization triggers the self-assembly of PBI-9, which leads to an emission peak shift from 540 nm to 690 nm, corresponding to monomeric emission to excimer emission. This shift was applied for the detection of heparin. Importantly, the interaction between PBI-9 and heparin is not affected by protamine, resulting in high selectivity and minimal interference. PBI-9 is a promising tool for detecting heparin in clinical settings after excess heparin has been neutralized by protamine.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2024
·
IF 5.3
Zishuo Zhou,Yaxue Liu,Pei Xie,Zongning Yin
Atherosclerosis is a chronic multifactorial cardiovascular disease. To combat atherosclerosis effectively, it is necessary to develop precision and targeted therapy in the early stages of plaque formation. In this study, a simvastatin (SV)-containing prodrug micelle SPCPV was developed by incorporating a peroxalate ester bond (PO). SPCPV could specifically target VCAM-1 overexpressed at atherosclerotic lesions. SPCPV contains a carrier (CP) composed of cyclodextrin (CD) and polyethylene glycol (PEG). At the lesions, CP and SV exerted multifaceted anti-atherosclerotic effects. In vitro studies demonstrated that intracellular reactive oxygen species (ROS) could induce the release of SV from SPCPV. The uptake of SPCPV was higher in inflammatory cells than in normal cells. Furthermore, in vitro experiments showed that SPCPV effectively reduced ROS levels, possessed anti-inflammatory properties, inhibited foam cell formation, and promoted cholesterol efflux. In vivo studies using atherosclerotic rats showed that SPCPV reduced the thickness of the vascular wall and low-density lipoprotein (LDL). This study developed a drug delivery strategy that could target atherosclerotic plaques and treat atherosclerosis by integrating the carrier with SV. The findings demonstrated that SPCPV possessed high stability and safety and had great therapeutic potential for treating early-stage atherosclerosis.
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Songhao Yu,Guifen Tian,Liduan Li,Fei Wang,Kefeng Wang,Junyu Lei,Haijun Hao,Qinghong Xu
TpFO-PA, a novel spherical hollow mesoporous polyamide, was firstly synthesized by the reaction among 1,3,5-tris(4-aminophenyl)benzene (TAPB), furylamine and oxalyl chloride in using silica-gel nanoparticle as hard template, and the composite Cu(I)@TpFO-PA with high catalytic activities in C-N coupling reactions between (hetero)aryl bromide and (hetero)aryl amines under mild conditions was prepared basing on presence of N in the framework. A maximum activity of the catalyst with yield of C-N coupling product were about 311.9 g (product) /mol Cu(I) ·h and 95 % respectively, and the activity could be maintained at least 5 times after the catalyst was reused. The composite Cu(I)@TpFO-PA is a few heterogeneous catalysts reported in catalyzing coupling reaction between aromatic amines and brominated aromatic compounds.
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Soft Matter
·
2011
·Vol. 7
·期 18
·8516-8524
·
IF 4.457
Wei Xiong,Hanfu Wang,Yanchun Han
The synthesis and characterization of oligoaniline-containing dendron-rod-dendron dumbbell shape block oligomer (14G3A7) are presented. The unusual surface morphological evolution from fibrils to flat single-layer film and to a porous network is observed for 14G3A7 simply by oxidizing the block oligomer in solution. Based on the analysis of cryo-TEM as well as comparative studies on solution concentration and substrate properties, the series of changes in the surface morphology are explained through aniline conformational transition during oxidation. The network self-assembled from oxidized 14G3A7 contains a two dimensional close packing skeleton of aniline segment, which may find a wide range of applications in electronic sensitive devices.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Tong Luo,Xiaoliang Guo,Yuling Qiu,Daihui Zhang,Chuanwei Lu,Chunpeng Wang,Jifu Wang,Tongqi Yuan,Fuxiang Chu
Conductive pressure sensitive adhesives (PSA) used for wearable and smart electronic sensors have attracted a significant amount of attention recently. However, achieving multifunctional conductive PSA with the feature of temperature tolerance and sustainability via a convenient and environment-friendly approach still remains challenge. Herein, a novel cellulose-rosin based poly(esterimide) (PEI) was first prepared by esterification and imidization. Then, the cellulose-rosin based PEI was integrated with polymerizable deep eutectic solvents (PDES, 2-hydroxyethyl acrylate and triethanolamine as hydrogen bond donor, choline chloride as hydrogen bond receptor) and performed UV-induced polymerization for formation of the conductive PSA with dual network (DN). The DN structure and the existence of extensive hydrogen bonds endowed these cellulose-rosin based conductive PSA with excellent adhesion property (shear resistance more than 70 h, tack of 14.6 N and 180° peel strength of 148.1 N/m, are higher than that of some typical commercial PSA), exceptional UV-blocking, solvent-resistance (usable in low polar solvent) and temperature tolerance (perform well between −25 °C to 140 °C). Furthermore, these conductive PSA could be used as wearable sensor to monitor subtle movements and achieve real-time monitoring of interface adhesion states even under extreme environmental conditions. This work provides a green strategy for the next-generation of multifunctional PSA.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Ming Lei,Jinsheng Sun,Haiyan Zhu,Weian Huang,Zhixiang Cai
The increasing energy demand and environmental pressure require the utilization of high-performance and eco-friendly drilling fluid materials for oil/gas exploration. Herein, a green nanocomposite involving the core structure of silica (SiO 2 ), the resin shell structure of rosin dehydroabietic acid (DHAA) derivative [poly(DHAA- co -styrene) (PDS)], and the crown structure of hydrophilic layer [crosslinked poly(2-acrylamido-2-methyl-1-propanesulfonic acid- co - N , N -dimethylacrylamide) (CAD)] was prepared through semi-continuous emulsion polymerization and utilized as a high-performance and multifunctional additive for drilling fluid. The optimal composition of core, shell and crown was determined to be 0.3: 10: 2 in mass, and the DHAA component accounted for 50 wt% in the shell structure and the molar ratio of 2-acrylamido-2-methyl-1-propanesulfonic acid and N , N -dimethylacrylamide in the crown was 3:7. The core-shell-crown nanocomposite (SiO 2 -PDS-CAD) exhibited a well-organized multi-layered nanostructure with an effective encapsulation of PDS on nano-SiO 2 and CAD on PDS, facilitating a uniform nano-dispersion of SiO 2 -PDS-CAD. The bulky copolymerized rosin-based segments coupled with nano-SiO 2 resulted in high thermal stability of SiO 2 -PDS-CAD and broadened the softening point of raw rosin from 87°C to 141°C. Meanwhile, the environmental assessments of acute toxicity and biodegradability showed that SiO 2 -PDS-CAD was nontoxic and readily biodegradable, and the higher incorporation of rosin components enabled SiO 2 -PDS-CAD more biodegradable in contrast to the non-biodegradability of the analog without rosin. Moreover, SiO 2 -PDS-CAD showed versatile functions in bentonite-based drilling fluid by maintaining high yield points, lowering fluid loss and enhancing nano-porous plugging capacity (100–400 nm), especially at elevated temperatures (140–180°C). A maximum increment of 1200 % on yield point occurred after aging 170°C, and the highest improvement of approximately 72 %-75 % on fluid loss occurred at 150–180°C. It also could effectively inhibit clay swelling and decrease the lubrication coefficient. The enhancement mechanism was revealed to be the core-shell-crown synergistic effects, in which the hydrophilic crown contributed to the dispersion stability of SiO 2 -PDS-CAD and affinity with bentonite clay, and the rigid bridging of core and flexible deformation of rosin shell strengthened the interparticle interactions. The study highlighted a novel strategy for preparing high-value-added rosin-based biomass material for green multifunctional applications in water-based drilling fluids.
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