MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 3
·951-959
·
IF 4.58
Zhang Yuhuan,Wang Yanru,Zhu Wenxin,Wang Jing,Yue Xiaoyue,Liu Wei,Zhang Daohong,Wang Jianlong
The capability of multi-level logic operations in biological diagnosis is far from being fully realized. In particular, the simplification of logic judgments to realize rapid, on-site complex diagnoses is still a key issue in bioelectronics. The authors here describe the construction of a colorimetric multilevel DNA circuit that incorporates two IMPLY gates and a sample extraction technology (SET) with anti-BPA aptamer as a co-recognizing element and the color of gold nanoparticles as the output signal. The circuit can perform multi-bioanalysis of the plasticizers and hormone mimetics bisphenol A (BPA) and bisphenol S (BPS). The assay is based on the finding that the aptamer against BPA can recognize both BPA and BPS. This DNA logic detection system is simple, fast, sensitive and selective because of the utilization of a co-recognition element which decreased input numbers. This, in turn, cascades multiplex Boolean logic gates and simplifies the diagnostic challenge. Both BPA and BPS can be determined by photometry at 620 nm, the limit of detection being 1.5 ng⋅mL −1 for BPA and 1.3 ng⋅mL −1 for BPS. Application to (spiked) water samples shows good analytical performance in terms of recovery (95.4 to 106.8%), linear range (4.4 to 66 ng⋅mL −1 for BPA, 2.5 to 75 ng⋅mL −1 for BPS) and correlation coefficients (>0.98). In our perception, the method represents a simple route for the fabrication of colorimetric multi-level DNA circuits. It may shorten the gap between bioelectronic logic circuits and high throughput real sample analysis.
Illustration of sample extraction treatments (SET) of bisphenol A (BPA) and bisphenol S (BPS) and the three-input IMPLY1-IMPLY2 logic operation with BPA, BPS and anti-BPA aptamer as inputs.
研究领域:
生物化学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ANALYST
·
2021
·Vol. 146
·期 24
·7593-7600
·
IF 4.616
Ling Lei,Caoling Li,Wensheng Huang,Kangbing Wu
Developing a sensitive and rapid detection method for 4-chlorophenol (4-CP) and 4-nitrophenol (4-NP) is very important due to their high toxicity. In this work, bulk Ti3AlC2 powder was etched to Ti3C2Tx for the first time through a hydrothermal reaction in NaF/HCl solution. After ultrasonication in N-methylpyrrolidone (NMP), Ti3C2Tx powder was successfully exfoliated into multilayered Ti3C2Tx nanosheets (i.e. Ti3C2Tx MXene). The prepared Ti3C2Tx MXene not only has a large electrochemical surface area for the oxidation of 4-CP and 4-NP, but also lowers their electron transfer resistance. As a result, the oxidation signals of 4-CP and 4-NP are significantly improved on the surface of the Ti3C2Tx MXene. Based on the remarkable signal amplification of the Ti3C2Tx MXene, a sensitive and rapid method was developed for the simultaneous detection of 4-CP and 4-NP. The linear range is from 0.1 to 20.0 μM for 4-CP, and from 0.5 to 25.0 μM for 4-NP, with detection limits of 0.062 μM (4-CP) and 0.11 μM (4-NP). This method was used in wastewater samples, and the accuracy was confirmed to be good by high-performance liquid chromatography.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Yu Xin,Ning Wang,Chunli Wang,Wei Gao,Mingli Chen,Nazhen Liu,Jizhou Duan,Baorong Hou
A covalent organic framework (COF) modified carbon paste electrode (CPE) was used for the electrochemical detection of hazardous hydroquinone (HQ) and catechol (CC). Due to the advantages of TpBD-COF (large surface area, abundant functional groups and high chemical stability), rapid quantitative determination of HQ and CC was accomplished by differential pulse voltammetry (DPV). Under the optimal conditions, the resultant sensor showed an extended linear response range for HQ and CC (1–2000 μmol L −1 ), and the detection limits were 0.31 and 0.46 μmol L −1 (S/N = 3) respectively. The simultaneous determination of HQ and CC can be accomplished by data deconvolution. In binary solutions with one constant constituent concentration, a linear relationship was established between the deconvoluted peak current and concentration of the changing constituent. In addition, the electrochemical sensor showed strong anti-interference ability, good reproducibility (a relative standard deviation of 0.99% for HQ and 0.77% for CC, n = 5) and applicability in real sample detection (with spiking recoveries from 97.7% – 101.6% for HQ and 100.3% – 103.3% for CC). These results demonstrate that COF modified carbon materials are promising candidates for efficient electrochemical detection of phenolic compounds .
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Haiyan Zhang,Yitong Chen,Yanhui Wei,Xiaokang Zhang,Hongchao Ma
The development of metal-based redox nanozymes represents a new frontier in pollutant sensing. In this field, designing highly active nanozymes and precisely regulating their enzymatic activity are key challenges. In this work, we report the construction of a copper peroxide@polydopamine (CuO2@PDA) nanozyme with dual enzyme-like activity, mimicking the active centers of laccase and peroxidase. Here, CuO2 acts as the catalytic center, while PDA serves as a carrier to prevent CuO2 aggregation and promotes conversion of CuII/CuI active sites via the reduction effect of its surface catechol groups to complete the catalytic cycle. As expected, the obtained CuO2@PDA nanozyme exhibits significant laccase- and peroxidase-mimetic activities. Moreover, its dual enzymatic activity can be systematically switched by adjusting pH and temperature. Specifically, laccase activity dominates near neutral pH, while CuO2 decomposition into Cu ions and H2O2 at acidic pH triggers peroxidase activity. Similarly, CuO2@PDA exhibits temperature-dependent dual enzymatic activity with peroxidase activity prevailing at low temperatures and laccase activity at high temperatures. According to enzymatic performance and XPS results, a possible catalytic mechanism of the dual enzymatic activity of CuO2@PDA has been proposed. Then, based on the pH-dependent dual enzymatic activity of CuO2@PDA, we constructed a detection system for the isomers of organic pollutants, catechol (CC) and hydroquinone (HQ). The laccase-like activity of CuO2@PDA enables direct oxidation of CC into yellow o-benzoquinone, while HQ discolors the preoxidized substrate generated via the peroxidase-like activity of CuO2@PDA. Moreover, selective sensing for CC and HQ with high sensitivity was achieved in real water samples. This approach can guide the design of nanozymes with multienzymatic activity and unveil their potential uses in environmental pollutant discrimination.
研究领域:
环境科学
·
生物化学
·
纳米材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Xiaoqing Huang,Haoyu Su,Ping Hu,Yueyuan Ye,Duo Wang
To fully utilized the high value-added phenolic compounds in biomass pyrolysis bio-oils, a heterogeneous extraction method was developed in this study to separate 4-ethylguaiacol, guaiacol, and eugenol from bio-oil one by one. Based on the high selectivity of coordination intermediates generated between Ca 2+ and phenolic compounds with hydroxyl and methoxy groups towards the parent phenol, the reaction intermediate between each of 4-ethylguaiacol, guaiacol, eugenol and Ca 2+ was used as the extracting agents. Influencing parameters investigated were the sequence of extracting three phenolic compounds from the model bio-oil, the optimal extraction conditions, and the Ca 2+ distribution in the original extracting agents at the end of the reaction. The optimal extraction sequence was determined to be 4-ethylguaiacol, eugenol and guaiacol through the evaluation of multiple experiments changing their addition sequence. Under the conditions of 25 °C reaction temperature, 45 min reaction time, and pH value of 7, the extraction efficiency of 4-ethylguaiacol, eugenol and guaiacol from bio-oil reached 60.6 %, 46.1 % and 60.7 %, respectively. Meanwhile, the purity of these three phenolic compounds achieved 62.4 %, 90.0 % and 89.0 %.
研究领域:
化学工程
·
生物质能
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2024
·
IF 2.7
Shufeng Lin,Zhonghua Sun,Zhenzhen Wang,Qiumin Zhou,Anwei Wang,zhong wu,Junfeng Qian,Ming-Yang He,Qun Chen
Bisphenol A (BPA) is ubiquitous in industrial production and daily life. However, BPA is harmful to the health of fetuses and children due to its potential endocrine-disrupting effects. Hydrogenated bisphenol A (HBPA), an alicyclic diol generated from hydrogenating the double bonds of two benzene rings in the BPA molecule, is supposed to be a perfect substitute for BPA due to its stability and non-toxicity. Nevertheless, the rational design of high-performance catalysts for selectively converting BPA into HBPA remains a significant challenge. In this work, highly dispersed Ru immobilized by Al2O3 modified with Ni promoter (Ru/Ni-Al2O3) have been constructed, enabling BPA selective hydrogenation to produce HBPA under mild conditions. The doping of Ni promoter around Ru active sites effectively regulated the selectivity of target reaction. Both characterization and experimental results validated that the Ni promoter manipulated the electronic state of Ru through strong electron interaction between Ni and Ru, and thus the catalytic performance. In addition, the catalytic performance was also dependent on other reaction parameters such as H2 pressure, reaction temperature, liquid hourly space velocity (LHSV), and hydrogen-oil volume ratio. The optimized Ru/0.1Ni-Al2O3 catalyst achieved a BPA conversion of 100% and an HBPA selectivity of 96.4% under optimal reaction conditions (6 MPa H2, 140 oC, 0.42 h-1 LHSV, and 1500:1 hydrogen-oil volume ratio).
研究领域:
催化化学
·
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2015
·Vol. 16
·期 6
·13507-13527
·
IF 2.862
Arshad Mehmood Abbasi,Xinbo Guo,Xiong Fu,Lin Zhou,Youngsheng Chen,Yong Zhu,Huaifeng Yan,Rui Hai Liu
Mango (Mangifera indicaL.), also called “the king of fruits”, is one of the most popular fruits in tropical regions. Pulp and peel samples of mango cultivars were analyzed to estimate total phenolic, total flavonoid and total anthocyanin contents. Phenolic acids, hydrophilic peroxyl radical scavenging capacity (hydro-PSC) and oxygen radical scavenging capacity (ORAC)in vitrowere also determined. Total phenolics and flavonoid contents were found maximum in the peel of Xiao Tainang and Da Tainang cultivars, respectively, whereas Xiao Tainang also exhibited significant antioxidant capacity. Noteworthy, concentrations of gallic acid, protocatechuic acid, ferulic acid, chlorogenic acid and caffeic acids at 79.15, 64.33, 33.75, 27.19 and 13.62 mg/100 g fresh weight (FW) were quantified for Da Tainang, Xiao Tainang and of Jidan cultivars, respectively. Comparatively, a higher level of phenolics and significant antioxidant capacity in mango peel indicated that it might be useful as a functional food and value-added ingredient to promote human health.Keywords:mango;phenolics;flavonoids;anthocyanins;phenolic acids;ORAC;hydro-PSC
研究领域:
食品科学
·
植物化学
✓ 已验证
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
S.B Mayil Vealan,Sekar Chinnathambi
Environmental endocrine-disrupting chemicals, Bisphenol A (BPA) and 4-Nitrophenol (4-NP), pose significant risks to reproductive health in both animals and humans. Here, we introduce the first utilization of the 4-leg spin ladder compound La 2 Cu 2 O 5 as an electrode material for electrochemical sensor. Nanostructured La 2 Cu 2 O 5 was synthesized via a straightforward Sol-Gel method and thoroughly characterized using X-ray photoelectron spectroscopy, high-resolution transmission electron microscopy, and powder X-ray diffraction. La 2 Cu 2 O 5 nanoparticles modified glassy carbon electrode (GCE) exhibited a significant electrocatalytic activity towards the oxidation of BPA and 4-NP in phosphate buffer saline (pH 7.0). Square wave voltammetry studies revealed lowest detection limits of 3 nM for BPA and 2.6 nM for 4-NP over a wider concentration range of 0.01–500 μM. Notably, this study marks the first utilization of La 2 Cu 2 O 5 for simultaneous electrochemical detection of BPA and 4-NP, demonstrating its potential in this field. Furthermore, the sensor exhibited good sensitivity, reproducibility, and selectivity towards BPA and 4-NP, even in the presence of similar potential organic and inorganic interferents. Additionally, the newly developed sensor enabled simultaneous quantification of BPA and 4-NP in real samples such as packaged milk, river water, and plastic bottles, achieving recovery rates above 95%. Importantly, our results underscore the leaching of BPA into water from thin and thick plastics at elevated temperatures (40 °C–80 °C), emphasizing the utility of the proposed sensor for rapid and simultaneous detection of BPA and 4-NP in environmental and food matrices.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·Vol. 142
·期 14
·e56693
·
IF 2.8
Zi-Ang Xia,Long Wang,Chaojie Li,Xue Li,Jingxue Yang,Baoming Xu,Heng Zhang
The augmentation of chitosan's (CS) antioxidative and antibacterial properties via grafting with phenolic acids constitutes a significant method for expanding the utility of chitosan. In this investigation, four phenolic acids (gallic acid, GA; protocatechuic acid, PCA; hydroxybenzoic acid, HA; and salicylic acid, SA) were conjugated with CS utilizing carbodiimide (EDC)-mediated grafting. The resultant phenolic acid-CS graft copolymers underwent characterization employing infrared spectroscopy, x-ray diffraction, and thermogravimetric analysis. Furthermore, ex vivo antioxidative and antibacterial assays were performed. Findings revealed that among the synthesized phenolic acid-chitosan graft copolymers, gallic acid-chitosan (GA-CS) demonstrated the highest antioxidative and antibacterial efficacy, primarily attributed to its elevated grafting ratio and abundance of hydroxyl groups. The antioxidative and antibacterial performances of the remaining three graft copolymers followed this order: CS-PCA > CS-HA > CS-SA, aligning with the trend in grafting ratios. This correlation arises from the higher grafting ratios of copolymers yielding more active OH groups, thereby exhibiting enhanced antioxidative and antibacterial properties. Phenolic acid-chitosan graft polymers exhibit promising antioxidative and antibacterial attributes, making them suitable additives for application in the food preservation packaging industry.
研究领域:
食品科学
·
材料科学
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Yichen Zhen,Qiang Zhang,Xiaoyan Zhang,Guanteng Zhang,Xiaoxin Chen,Chunxia Zhao
Chlorophenols (CPs) are still used as raw material or intermediate in some industries. Photocatalytic oxidation is free from secondary pollution, but the efficiency is restricted by some main factors. In this study, a novel high efficiency tubular up-flow magnetic film (TUMF) photocatalytic system was investigated based on the magnetic lanthanum doping core-shell Fe 3 O 4 @SiO 2 @TiO 2 (La-FST) nanoparticles. When the dosage of La-FST was 0.4 g/L, the flow velocity was 94.2 mL/min, and the circulated irradiation of 15 W maintained 40 min, the average removal rate of 2,4-dichlorophenol (2,4-DCP) was reduced significantly from 10 mg/L to 0.0803 mg/L by TUMF system, meeting the limits of the particular items (0.093 mg/L) from national environmental quality standards for surface water, avoiding the problem of photocatalyst separation and loss. The photoinduced holes ( h + ) was the key active radical to oxidize 2,4-DCP, and the main factors of TUMF system could be well controlled to achieve satisfactory effluent quality. A prediction method of photocatalytic reaction time in a multistage series TUMF system was established to remove 2,4-DCP from 100 mg/L to 0.5 mg/L, saving 86 min. The novel high-efficiency TUMF system provides a technical selection for the photocatalytic degradation of CPs and other refractory organics.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Qiong Dai,Qun Yu,Yuan Tian,Xiaolin Xie,Aixin Song,Frank Caruso,Jingcheng Hao,Jiwei Cui
We report a facile inking strategy for visual information storage (e.g., writing, printing, and beyond) via surface modification of substrates with polyphenols and subsequent in situ formation of metal–phenolic networks (MPNs) on the substrates. The reported technique has several advantages compared with current printing techniques. Diverse substrates can be used to fulfill the requirements for different applications (e.g., printing, writing, painting, and stamping). A range of colors (e.g., yellow, blue, and green) can be realized using different polyphenols (e.g., tannic acid, gallic acid, and pyrogallol) and metal ions (e.g., CuII, FeIII, and TiIV). The disadvantages (e.g., ink precipitation, color fading) associated with writing or printing using traditional ink can be overcome. The obtained paintings can be easily removed by acids enabling the recycling of substrates. The reported strategy provides a new avenue for the development of portable, nontoxic, and green technologies for writing, printing, and beyond, which expands the applications of MPN-based materials.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER COMPOSITES
·
2014
·Vol. 36
·期 8
·1531-1540
·
IF 1.455
Xiang-Ming Hu,Yan-Yun Zhao,Wei-Min Cheng
Six types of phenolic foaming resins were synthesized at room temperature with different formaldehyde/phenol (F/P) ratios in this study. The effects of F/P ratios on physicochemical characteristics and foaming properties of the resulting resins were analyzed based on viscosity, solids content, hydroxymethyl index, residual monomer content, molecular structure of the foaming resin, flame retardancy, and foam compression strength measurements. The results of the present study indicated that viscosity and solids content of the foaming resins increased with an increase in F/P; the hydroxymethyl index of the resin first increased and then decreased with an increase in F/P, reaching its maximum at F/P = 1.6; the trimer, tetramer, and pentamer contents of the resins increased with an increase in F/P. Nuclear magnetic resonance ( 13 C NMR) spectral analysis indicated that the presence of para / para -methylene, para -hydroxymethyl, and ortho -hydroxymethyl groups in the resin gradually increased with an increase in F/P; the proportions of ortho/ortho - and ortho / para -methylene bonds of the resin increased as F/P was increased. The increase in F/P was demonstrated to be conducive to improving the compression strength, thermal stability, and flame retardancy of the phenolic foam and reducing its peak heat release rate and total smoke release. The morphology of phenolic foams show that the closed cell content in the PF foam increases with the F/P ratio until it reaches a ratio of 1.6. Furthermore, the cell size becomes more uniform. POLYM. COMPOS., 36:1531–1540, 2015. © 2014 Society of Plastics Engineers
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）