Nanoscale Horizons
·
2025
·Vol. 10
·期 3
·561-567
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IF 6.6
Yu Xing,Haoshen Ye,Guowei Du,Xu Li,Le-Ping Miao,Junchao Zhang,Xiong Luo,Xiyu Chen,Haoran Ye,Aoli Shen,Zhicheng Wang,Yumeng You,Shuai Dong,Linglong Li
The coexistence of electric and magnetic orders with intrinsic coupling, referred to as magnetoelectric coupling in multiferroics, has been extensively studied in oxide materials but remains relatively unexplored in van der Waals materials. Among these, CuCrP2S6 (CCPS) is notable for its emergent antiferromagnetic (AFM) and antiferroelectric (AFE) characteristics. However, investigations into magnetoelectric coupling in CCPS are limited, and the effects of dopants on its magnetic properties have yet to be fully addressed. In this study, we synthesized CuCr1−xFexP2S6 (CCFPS) samples using the chemical vapor transport (CVT) method to investigate the influence of iron doping on the magnetic and nonlinear optical properties of the CCFPS system. Our results indicate that the AFM state is preserved, while the Néel temperature (TN) varies with the doping concentration. First-principles calculations were employed to assess the exchange interactions among magnetic atoms. Notably, for samples with doping concentrations x < 0.5, we observed both magnetic-dielectric coupling and second harmonic generation (SHG) effects. However, these effects were absent at higher doping levels. Furthermore, our analysis revealed a distinct odd–even dependence of SHG, suggesting the presence of interlayer symmetry-breaking coupling. These findings advance our understanding of two-dimensional (2D) multiferroic materials and lay the groundwork for designing and optimizing magnetoelectric coupling materials with enhanced performance.
研究领域:
凝聚态物理
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材料科学
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二维材料
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多铁材料
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自旋电子学
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产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Yuhan Fu,Lirui Hou,Shirui Wang,Hongbo Hu,Shutao Yin
The accumulation of iron potentially results in organ damage and various diseases. Polyphenols can chelate iron in solution; however, there is a paucity of direct evidence supporting their efficacy in treating iron overload- mediated damage. This study sought to assess the chelating efficacy of galloyl glucoses with iron, as well as the potential of 1,2,3,4,6-Pentagalloyl glucose (PGG) to mitigate ferroptosis and liver injury induced by iron overload. RSL3 was employed to establish a cell model, while mice were treated with dextrose iron. PGG markedly mitigated cell death and the accumulation of lipid peroxides in RSL3 treated cells by chelating iron and inhibiting the RSL3-mediated autophagic degradation of ferroportin. Additionally, oral administration of PGG significantly reduced iron accumulation, inhibited oxidative stress, and ameliorated liver injury induced by iron overload. PGG has the potential to serve as an intervention for cell death and liver damage resulting from iron overload. The findings aim to contribute to the development of strategies for the intervention of iron overload-related injuries.
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DOI
PubMed
高影响因子
Chemical Science
·
2024
·
IF 7.6
Wei-Xing Chen,Zi-Sheng Li,Harry W. T. Morgan,Cong-Cong Shu,Zhong-Ming Sun,John E. McGrady
We report here the synthesis and characterization of two endohedral Zintl-ion clusters, [Fe4Sn18]4− and [Fe4Pb18]4−, which contain rhombic Fe4 cores. The Fe–Fe bond lengths are all below 2.5 Å, distinctly shorter than in the corresponding Cu clusters, indicating the presence of Fe–Fe bonding. Subtle differences in the structure of the Fe4 core between the two clusters suggest that the change in tetrel element causes a change in electronic ground state, with a very short Fe–Fe bond length of 2.328 Å present across the diagonal of the rhombus in the lead case.
研究领域:
化学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Journal of Cleaner Production
·
2021
·
IF 9.297
Yun Li,Haotian Xue,Pekka Taskinen,Ari Jokilaakso,Chaobo Tang,Wei Jin,Minna Rämä,Yongming Chen,Shenghai Yang
In view of the issues of low efficiency and environmental pollution existing in current antimony production, this work proposes an innovative and cleaner process to extract antimony from stibnite concentrate and co-treat goethite residues. The mechanisms of antimony extraction and zinc, iron, sulfur conservation was thermodynamically and experimentally investigated. The results show that iron- and zinc-bearing components in the goethite residue firstly reacted and releasing Fe x O y and ZnO, then stibnite (Sb 2 S 3 ) quickly converted to senarmontite (Sb 2 O 3 ) in the presence of Fe x O y and ZnO. Intermediate Sb 2 O 3 was subsequently reduced to metallic Sb. Bench-scale experiments of antimony extraction from stibnite concentrate with goethite residue as sulfur-fixing agent validated that 85.7% of Sb was directly recovered as crude antimony bullion, only around 7.4% antimony volatilized to fume. Pb, As, Au, and Ag tended to also be co-enriched in the bullion. 97.4% of sulfur, 88.8% of zinc and 86.1% of iron were recovered and fixed simultaneously. Sulfur in Sb 2 S 3 , iron and zinc contained in goethite residues was conserved in matte as marketable Fe 2 Zn 3 S 5 , FeS, and ZnS, instead of forming gaseous SO 2 . This novel process is a promising recycling and co-treatment alternative for various secondary iron- and zinc-containing materials.
研究领域:
冶金学
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环境科学
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DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Xiaoli Bao,Xiuqing Liao,Zhongqiang Zhu,Ling Jiang,Daoxin Wang
Acute lung injury (ALI) represents a life-threatening condition with limited therapeutic options. Emerging evidence suggests that ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation, is a key pathological mechanism underlying ALI. Therefore, we systematically investigated the key role of ferroptosis in ALI pathogenesis using a lipopolysaccharide (LPS)-induced mouse model of sepsis-related ALI. Based on this finding, we engineered polyvinylpyrrolidone-assembled cobalt hexacyanoferrate nanocatalysts (CoHCF NCs) as a ferroptosis inhibitor. These nanocatalysts exhibited dual functions: efficient chelation of free iron ions and strong antioxidant activity. In vivo experiments showed the promising therapeutic efficacy of CoHCF NCs, while in vitro studies using erastin-induced ferroptosis in alveolar epithelial cells confirmed their strong ability to reverse ferroptotic processes. To explore the underlying mechanisms, we employed RNA sequencing, which revealed that CoHCF NCs exert their antiferroptotic effects through a transcriptional network involving antioxidant response enhancement, and iron ion homeostasis regulation. Due to their high ferroptosis-inhibitory capacity and biocompatibility, CoHCF NCs represent a promising therapeutic candidate for ALI.
研究领域:
呼吸病学
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纳米医学
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分子病理学
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氧化应激
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重症医学
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药理学
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细胞生物学
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED TOXICOLOGY
·
2023
·
IF 3.3
Xiuli Liu,Guilan Li,Shaoxiong Chen,Huiyun Jin,Xiaodong Liu,Linfang Zhang,Zhaohui Zhang
Beryllium sulfate (BeSO 4 ) can result to lung injuries, such as leading to lipid peroxidation and autophagy, and the treatment of beryllium disease has not been well improved. Ferroptosis is a regulated cell death process driven by iron-dependent and lipid peroxidation, while ferritinophagy is a process mediated by nuclear receptor coactivator 4 (NCOA4), combined with ferritin heavy chain 1 (FTH1) degradation and release Fe 2+ , which regulated intracellular iron metabolism and ferroptosis. Hydrogen sulfide (H 2 S) has the effects of antioxidant, antiautophagy, and antiferroptosis. This study aimed to investigate the effect of H 2 S on BeSO 4 -induced ferroptosis and ferritinophagy in 16HBE cells and the underlying mechanism. In this study, BeSO 4 -induced 16HBE cell injury model was established based on cellular level and pretreated with deferoxamine (DFO, a ferroptosis inhibitor), sodium hydrosulfide (NaHS, a H 2 S donor), or NCOA4 siRNA and, subsequently, performed to detect the levels of lipid peroxidation and Fe 2+ and the biomarkers of ferroptosis and ferritinophagy. More importantly, our research found that DFO, NaHS, or NCOA4 siRNA alleviated BeSO 4 -induced ferroptosis and ferritinophagy by decreasing the accumulation of Fe 2+ and lipid peroxides. Furthermore, the relationship between ferroptosis, ferritinophagy, H 2 S, and beryllium disease is not well defined; therefore, our research is innovative. Overall, our results provided a new theoretical basis for the prevention and treatment of beryllium disease and suggested that the application of H 2 S, blocking ferroptosis, and ferritinophagy may be a potential therapeutic direction for the prevention and treatment of beryllium disease.
研究领域:
毒理学
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细胞生物学
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药理学
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肺科学
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产品关联
DOI
PubMed
高影响因子
ChemElectroChem
·
2021
·Vol. 8
·期 24
·4817-4825
·
IF 4.59
Jie Zhu,Qian Zhang,Sudong Yang,Lin Chen,Peng Zhao,Qiang Yan
Graphical Flexibility approach : A facile two-step process for fabricating a distinctive Fe/Fe 3 O 4 composite deposited on carbon fabric as a negative electrode for a flexible nickel-iron battery is reported. The assembled battery exhibited a high voluminal capacity with a stable operating voltage up to 1.7 V, long-term cyclic stability as well as good mechanical stability and flexibility. The nickel-iron (Ni−Fe) battery is a competitive alternative for electrochemical energy storage, owning to its low cost, high safety, and strong auto-adaptive ability. However, the self-discharge and passivation of the negative electrode are the two main issues. In this work, a rock-like Fe/Fe 3 O 4 composite is synthesized and deposited on carbon fabric (Fe/Fe 3 O 4 @CF) by facile electrodeposition and annealing technologies to serve as a binder-free anode, which exhibits a large areal capacity of 0.466 mAh cm −2 and long-term cycling durability. Moreover, the flexible device is assembled by employing Fe/Fe 3 O 4 @CF-750 as anode and Ni(OH) 2 @CF as cathode. The above battery displays an enhanced operating voltage up to 1.7 V, impressive mechanical flexibility, outstanding cycling stability (86.2 % retention of initial value over 6000 charge-discharge cycles), and satisfactory voluminal capacity of 1.33 mAh cm −3 , indicating its potential application for energy supply systems of modern wearable electronics.
研究领域:
材料科学
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电化学
·
能源存储
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Jing Liu,Keyou He,Shengyin Tang,Ting Wang,Zhenghua Zhang
Coagulation-membrane filtration hybrid process has been widely applied in water treatment to improve water quality and alleviate membrane fouling. Herein, we systematically investigated the comparable effect of ferrate, ferrous and ferric pretreatment on fouling alleviation of ceramic membrane in reclaimed water treatment. Our results showed that the pretreatment of ferric, ferrous and ferrate remarkably alleviated membrane fouling with the fouling alleviation performance following the order: ferrate > ferrous > ferric > control. The t crit (subcritical fouling time) after which the fouling rate (dTMP/dt) became much more severe was remarkably extended from 0 (control) to 432 (ferric), 576 (ferrous) and 888 h (ferrate), respectively. Meanwhile, hydraulically reversible fouling resistance had the greatest contribution (58.3%) to the overall fouling resistance in the control case, however, hydraulically irreversible membrane fouling caused by inorganics ( R ir-citrate ) became more severe in long-term operation with the contribution of R ir-citrate to the total fouling resistance of 40.7%, 46.3% and 50.3% in the cases with ferric, ferrous and ferrate pretreatment, respectively. Moreover, the redundancy analysis results showed that the alleviated membrane fouling was principally owing to the sharp reduction of organic matters and the significant increase of particle size and particle concentration in influent. Compared with ferric and ferrous, ferrate had the best fouling alleviation performance, which was mainly due to its dual functions of chemical oxidation (including OH, Fe(V) and Fe(IV)) and coagulation (ferric oxyhydroxides).
研究领域:
环境科学
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水处理工程
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产品关联
DOI
高影响因子
Metals
·
2022
·Vol. 12
·期 5
·871
·
IF 2.695
Cui Wang,Jianliang Zhang,Wen Chen,Xiaolei Li,Kexin Jiao,Zhenping Pang,Zhongyi Wang,Tongsheng Wang,Zhengjian Liu
The corrosion resistance to molten iron of four kinds of carbon bricks used in blast furnace hearth were investigated to elaborate the corrosion mechanism through the macroscopic and microscopic analysis of carbon bricks before and after reaction and thermodynamic analysis. The macroscopic analysis showed that brick A had the lowest degree of corrosion and highest uniformity at different heights, attributing to its moderate carbon content of 76.15%, main phases of C, Al2O3, SiC, and Al6Si2O13(mullite), and lower resistance to molten iron infiltration, etc. The microscopic analysis showed that all the carbon bricks had more and larger pores than the original carbon bricks. The phenomena of the iron beads adhering to carbon brick and iron infiltration were observed between the interface of carbon brick and molten iron. In addition, the obvious corrosion process was presented that the carbon matrix was broken and peeled off during the iron infiltration process. For the carbon brick being corroded, the dissolution of carbon was the predominant reaction. The higher the carbon solubility of the molten iron, the easier the corrosion on the carbon brick. Al2O3and SiC enhanced the corrosion resistance to molten iron of carbon bricks, and SiO2could react with carbon to form pores as channels for the penetration of molten iron and increase the corrosion on carbon bricks. A higher graphitization degree of carbon bricks was beneficial to lessen their corrosion degree. The corrosion on carbon bricks by molten iron could be attributed to three aspects: carburization, infiltration, and scouring of molten iron. The carburization process of molten iron was the main reaction process. The molten iron infiltration into the carbon bricks facilitated the dissolution of carbon and destroyed the structure and accelerated the corrosion of the carbon bricks. The scouring of molten iron subjected the iron–carbon interface to interaction forces, promoting the separation of the exfoliated fragmented carbon brick from the iron–carbon interface to facilitate a new round of corrosion process.Keywords:carbon brick;corrosion resistance to molten iron;carburization;iron infiltration
研究领域:
材料科学
·
冶金工程
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产品关联
DOI
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2024
·
IF 6.2
Wenli Guo,Jinjin Zhang,Xiaoqian Zhang,Quanzhong Ren,Guangzhe Zheng,Jianxin Zhang,Guoxing Nie
Cadmium (Cd) pollution is considered a pressing challenge to eco-environment and public health worldwide. Although it has been well-documented that Cd exhibits various adverse effects on aquatic animals, it is still largely unknown whether and how Cd at environmentally relevant concentrations affects iron metabolism . Here, we studied the effects of environmental Cd exposure (5 and 50 μg/L) on iron homeostasis and possible mechanisms in common carp. The data revealed that Cd elevated serum iron, transferrin saturation and iron deposition in livers and spleens, leading to the disruption of systemic iron homeostasis. Mechanistic investigations substantiated that Cd drove hemolysis by compromising the osmotic fragility and inducing defective morphology of erythrocytes. Cd concurrently exacerbated hepatic inflammatory responses, resulting in the activation of IL6-Stat3 signaling and subsequent hepcidin transcription. Notably, Cd elicited ferroptosis through increased iron burden and oxidative stress in livers. Taken together, our findings provide evidence and mechanistic insight that environmental Cd exposure could undermine iron homeostasis via erythrotoxicity and hepatotoxicity. Further investigation and ecological risk assessment of Cd and other pollutants on metabolism-related effects is warranted, especially under the realistic exposure scenarios.
研究领域:
环境科学
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毒理学
·
水生生物学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
Xinxi Zeng,Bingcheng Luo,Han Zhang,Xiaoqing Xi,Bo Li,Ji Zhou
Electric field-induced antiferromagnets with ultrahigh resonant frequencies without current flow in insulating materials is highly desired. This paper reports the terahertz (THz) responses of Γ 4 in rare-earth orthoferrite GdFeO 3 ceramics, which were manipulated using thickening and thermal methods. As the thickness was increased, the noise was greatly reduced, and increased peak heights of both the ferromagnetic resonances and antiferromagnetic resonances were observed. For the thermal control of THz responses in GdFeO 3 , the resonant frequencies of both the ferromagnetic resonances and antiferromagnetic resonances experienced a blue shift , and their peak heights increased. The detected shifts of the responses were determined by the changes in thermodynamic potential . Moreover, macroscopic properties were collected to verify the coexistence of ferromagnetism and antiferromagnetism .
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
ADVANCED MATERIALS
·
2025
·
IF 26.8
Kai Xiang,Zhiying Xiao,Zheng Jing,Yuzhou Li,Meng Li,Zhikang Su,Ziyu Huang,Tianli Wu,Ping He,Yining Zhang,Fengyi Liu,Mingxing Ren,Sheng Yang
Cigarette smoke (CS) disrupts mitochondrial iron homeostasis, causing excess free iron to generate reactive oxygen species, leading to oxidative stress and impairing tissue repair. For smokers undergoing bone defect repair, achieving precise control over the balance between mitochondrial free iron and stored iron, while simultaneously enhancing endogenous iron homeostasis, poses a considerable challenge. This study introduces the iron balance dual-drive strategy (IBDS), which efficiently chelates mitochondrial free iron and promotes ferritin synthesis to create a FerritinBank for iron deposition, thus optimizing endogenous iron homeostasis. IBDS is delivered through an injectable, biodegradable iron-capturing hydrogel (SilMA/gelMA/DPT). The released DPT selectively targets and chelates free iron within mitochondria, modulating mitochondrial dynamics to restore their function. This action is complemented by the promotion of ferritin synthesis, which serves to bolster endogenous iron homeostasis and suppress ferroptosis. Transcriptomic sequencing and experimental data suggest that DPT corrects energy metabolism abnormalities and promotes mitochondrial macromolecule synthesis. In vivo studies confirm that the iron-capturing hydrogel significantly improves the healing of smoking-induced calvarial bone defects. This is the first report of nanoparticles promoting ferritin synthesis to build an endogenous iron reservoir, highlighting the potential of the IBDS strategy for bone regeneration in smokers and other iron-overload-related conditions.
研究领域:
医学
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生物材料学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）