ANALYST
·
2019
·Vol. 144
·期 12
·3807-3816
·
IF 4.019
Xiaojun He,Chenglin Wu,Yuna Qian,Yahui Li,Lilei Zhang,Feng Ding,Hong Chen,Jianliang Shen
Over the past decades, gallium (Ga) compounds have gained importance in the field of cancer treatment. Gallium acts as an iron mimic and disturbs iron-dependent propagation and other processes in tumor cells. However, the toxicity of gallium was also well documented in vitro and in vivo in animals. Though the oral administration of gallium in humans is less toxic, it has also been shown that a long period of administration could induce tumor fibrosis. Chromium (Cr), a naturally occurring heavy metal, is commonly used in industrial processes and can cause severe health problems in humans. It has been found to be closely involved in the metabolism of nucleic acids, proteins and fats in humans. Cr(III) salts can be used as micronutrients and dietary supplements. However, similar to gallium (Ga3+), chromium (Cr3+) can build up to an excessive degree that is harmful to the human body. Therefore, it would be of great interest to develop chemosensing for the selective and sensitive detection of gallium and chromium ions in vitro and in vivo. Herein, we reported that an NBD-based (4-chloro-7-nitrobenzo-2-oxa-1,3-diazole) fluorescent probe (NBDT) was fabricated with demonstrated extraordinary specificity and sensitivity. A swift response toward Ga3+ and Cr3+ ions was discovered using fluorescence enhancement over a wide pH range and with cycle stability. Furthermore, lighted up by Ga3+ and Cr3+ ions in vitro, this NBDT sensor was successfully applied to detect exogenous Ga3+ and Cr3+ ions in MDA-MB-231 and HepG2 cells. Additionally, using zebrafish as the in vivo model, we demonstrated the capability of this NBDT for detecting and imaging Ga3+ and Cr3+ ions in zebrafish. Taken together, this NBDT has indicated great potential for detecting and monitoring Ga3+ and Cr3+ ions in vitro and in vivo.
研究领域:
生物化学
·
医学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
MINERALS ENGINEERING
·
2021
·
IF 4.765
Lihui Gao,Lizhang Wang,Yijun Cao,Shulei Li
A gallium ion-imprinted material (Ga-IIP-PP) was fabricated from persimmon peel using persimmon tannin as a functional monomer. Thereafter, it was applied for the selective adsorption of Ga ions from aqueous solutions containing other metal ions. The sorbent morphology and surface characterization data confirmed the successful loading of a gallium-imprinted layer onto the waste persimmon peel. The imprinted material exhibited a relatively smooth structure with few wrinkles, a negatively charged surface, and a low number of hydroxyl surface functional groups. The results of adsorption experiments revealed that Ga-IIP-PP could be applied in a wide range of Ga concentrations, while its highest adsorption capacity of 128 mg/g and adsorption rate of 0.0081 min −1 were achieved at pH = 3. Moreover, the synthesized Ga-IIP-PP exhibited high selectivity toward Ga ions even in binary systems with similar competitive ions. Finally, Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy were performed to elucidate the adsorption mechanism of Ga ions onto the Ga-IIP-PP surface, which primarily involved electrostatic adsorption and the cation exchange between the H + ions of OH/ COOH groups and Ga ions. This work demonstrates that the bio-sorbent prepared from waste persimmon peel is a promising adsorbent for recovering Ga ions from aqueous solutions.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
FUEL PROCESSING TECHNOLOGY
·
2018
·
IF 3.956
Tian-qi Lei,Yan-hu Cheng,Chang-xi Miao,Wei-ming Hua,Ying-hong Yue,Zi Gao
Dehydrogenation of ethane to ethylene in the presence or absence of CO 2 over silica-doped TiO 2 supported Ga 2 O 3 catalysts was investigated. The silica doping of TiO 2 support greatly improved the dehydrogenation activity in the absence of CO 2 , which can be ascribed to the increased acid sites. The initial activity in the presence of CO 2 decreased after the silica doping, due to the reduction in reverse water-gas shift ability. However, the selectivity as well as the stability increased, resulting in higher steady ethylene yield. A dynamic process consisting of alternative oxidative dehydrogenation/regeneration cycles by gasifying the carbon deposit with air for 10 min after each cycle of 6 h reaction was also performed and relatively stable ethane conversion ~30% and ethylene yield ~25% can be achieved. The different catalytic behaviors are probably associated with the different state of gallium species, caused by the different interaction between the Ga 2 O 3 and support.
研究领域:
化学工程
·
催化科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Chemical Biology
·
2023
·Vol. 4
·期 10
·774-784
·
IF 4.1
Xiaojun He,Bingjie Han,Runming Wang,Yu Guo,Richard Y T Kao,Hongyan Li,Hongzhe Sun,Wei Xia
The opportunistic pathogen Pseudomonas aeruginosa (P. aeruginosa) causes infections that are difficult to treat, which is due to the bacterial natural resistance to antibiotics. The bacterium is also able to form a biofilm that protects the bacterium from clearance by the human immune system and leads to chronic infection. Herein, we synthesized and characterized a novel gallium compound that interferes with both the iron metabolism and quorum sensing system of P. aeruginosa to achieve a significant bactericidal activity. The compound could substantially reduce the secretion of bacterial virulence factors as well as eliminate biofilm formation. Integrative omics analysis indicates that this compound can significantly disturb the gene transcription and metabolism of P. aeruginosa. The effectiveness of the gallium compound was further validated in mammalian cell and murine skin infection models. Our study offers a new strategy to design new gallium-based antimicrobials to combat P. aeruginosa infection.
研究领域:
微生物学
·
药理学
·
感染病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Yang Yang,Weishuang Fang,Ning Zhang,Huaicheng Xiang,Ying Tang,Jie Li,Liang Fang
CaEu C O 4 ( C Ga, Al) microwave dielectric ceramics were produced through a solid-state reaction. Orthorhombic olivine CaEuGaO 4 ( pnma ) exhibits a lower permittivity ( ε r = 9.7), a higher quality factor ( Q × f = 82,049 GHz), and a larger negative resonant frequency temperature coefficient ( τ f = −54.6 ppm/°C). CaEuAlO 4 , which has a similar chemical formula, exhibits a perovskite-like structure ( I 4/ mmm , K 2 NiF 4 -type), and its microwave dielectric properties are ε r = 18.9, Q × f = 43,132 GHz, and τ f = −1.6 ppm/°C. The difference in their structures is mainly caused by the properties of the Ga (III) atom. The difference in their dielectric properties can be proved to be affected by the “rattling” effect of Eu 3+ through the bond valence theory. The relationship between the covalence ( f c ) and the bond strength ( S ) was investigated, and the higher bond strength might be the main reason for the higher Q × f in CaEuGaO 4 ceramic.
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
FUEL
·
2024
·
IF 6.7
Jingyi Ma,Hui Yuan,Changcheng Liu,Jieguang Wang,Rongxin Zhang,Aizeng Ma
Propane dehydrogenation (PDH) is used to increase propylene production and to produce hydrogen as a by-product. Despite the widespread utilisation of Pt-loaded catalysts in industrial PDH operations, challenges such as excessive noble metal loading and coking persist in the face of rigorous reaction conditions. These hindrances limit to achieving the optimal economic efficiency. In this work, we report a method aimed at reducing Pt loading to only 0.05 wt% through synergistic modification of GaPt catalysts loaded on SiO 2 -Al 2 O 3 supports (i.e. SIRAL) with K and Ce. The resulting catalysts exhibit remarkable stability and elevated activity for propane dehydrogenation. The K + and SiO 2 could modulate the support surface acidity and immobilizes the active tetrahedral Ga 3+ sites, which improves the catalytic performance and reduce coke deposition. Furthermore, the inclusion of Ce decreases the electron density of the Pt species, stabilizing the atomically dispersed Pt and enhances the formation of active Pt sites, which effectively impedes the Pt agglomeration. As a result, the GaPtKCe/SIRAL10 catalyst demonstrates excellent catalytic performance, achieving 47% propane conversion and >96% propylene selectivity, while maintaining notable stability with 0.016 h −1 deactivation rate constant at 580 °C, even without hydrogen co-feed.
研究领域:
化学工程
·
催化材料科学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2020
·
IF 6.182
Min Li,Xian Wei,Shiliang Mei,Zhongjie Cui,Yizhou Fan,Bobo Yang,Zhuoqi Wen,Zhiyong Xiong,Le Wang,Fengxian Xie,Wanlu Zhang,Ruiqian Guo
Single-phased and white-emissive quantum dots (QDs) with a broadband spectrum are highly desirable as color converter for white light-emitting diodes (WLEDs) and have been less researched up till now. In this work, a series of copper gallium selenium based multicomponent QDs including quaternary Cu-Zn-Ga-Se (CZGSe) and quinary Cu-Mn-Zn-Ga-Se (CMZGSe) QDs were synthesized. From the perspective of thermodynamics and kinetics, the comparison between PL spectra under increasing temperatures via one-pot and hot-injection methods indicated that the formation of CZGSe cores originated from the diffusion of Cu + into Zn-Ga-Se nanoparticles . For wider spectra distribution, the incorporation of Mn 2+ gave rise to Mn d-d emission around 590 nm. Together with Cu-related emission about 500 nm and intrinsic emission around 430 nm, white emission of CMZGSe QDs could be realized well-tuned by incremental ZnSe deposition, whose chromaticity coordinates shifted along with the Planckian locus. These results about multicomponent alloyed QDs enrich mechanistic insight for the formation kinetics and reveal the potential to fabricate better color rendering WLEDs .
研究领域:
材料科学
·
光学工程
✓ 已验证
DOI
高影响因子
ACS Omega
·
2022
·
IF 4.132
Xiaofei Li,Xin Ding,Yuhang Du,Chao Xiao,Kang Zheng,Xianglan Liu,Xingyou Tian,Xian Zhang
Liquid metals (LMs) are playing an increasingly important role in the fields of flexible devices, electronics, and thermal management due to their low melting point and excellent thermal and electrical conductivity, and the transformation of LMs in deionized water has recently received much attention. In this paper, we investigate the transformation process of EGaIn microspheres in deionized water and propose a two-step process of microspherical transformation, whereby the microspheres are first deformed into a spindle shape and then into lamellar nanorods. It is also shown that the growth of GaOOH crystals drives the transformation. Based on this result, EGaIn microspheres with controllable transformation could be prepared, such as spindle or lamellar rod shapes, extending the application area of LMs.
研究领域:
材料科学
·
纳米技术
·
化学工程
✓ 已验证
DOI
PubMed
高影响因子
Catalysts
·
2019
·Vol. 9
·期 10
·854
·
IF 3.444
Jian Li,Xiangyu Li,Derun Hua,Xinning Lu,Yujue Wang
A series of gallium-containing MFI (Ga-MFI) zeolites with varying Ga2O3/Al2O3ratios were synthesized using hydrothermal synthesis and tested as catalyst in catalytic fast pyrolysis (CFP) of beech wood for aromatic production. The results show that the incorporation of Ga slightly reduced the effective pore size of Ga-MFI zeolites compared to conventional HZSM-5 zeolites. Therefore, the Ga-MFI zeolites increased the aromatic selectivity for smaller aromatics such as benzene, toluene, andp-xylene and decreased the aromatic selectivity for bulkier ones such asm-xylene,o-xylene, and polyaromatics in CFP of beech wood relative to HSZM-5. In particular, the yield and selectivity ofp-xylene, the most desired product from CFP of biomass, increased considerably from 1.64 C% and 33.3% for conventional HZSM-5 to 2.98–3.34 C% and 72.1–79.6% for the synthesized Ga-MFI zeolites. These results suggest that slightly reducing the pore size of MFI zeolite by Ga incorporation has a beneficial effect on optimizing the aromatic selectivity toward more valuable monoaromatic products, especiallyp-xylene, during CFP of biomass.Keywords:aromatics;biomass;MFI zeolites;gallium;catalytic fast pyrolysis
研究领域:
能源化学
·
材料科学
✓ 已验证
DOI
高影响因子
FUEL
·
2018
·
IF 4.908
Wenwu Zhou,Yanan Zhang,Xiujuan Tao,Yasong Zhou,Qiang Wei,Sijia Ding
The effects of gallium (Ga) modification on mesoporous Al 2 O 3 (MA) were studied, focusing on the morphology changes of the active phases and the application as catalyst support for catalytic performances for dibenzothiophene (DBT) hydrodesulfurization (HDS). MA samples with wide mesopore size distribution (MA-W), double mesopore size distribution (MA-D) and single mesopore size distribution (MA-S) were synthesized from the boehmite sol–gel via a hydrothermal synthesis method. The synthesized MA-S sample was modified with Ga 2 O 3 , and the corresponding sulfide NiMo supported catalysts were prepared. The as-synthesized samples were characterized by XRD, N 2 physisorption, NH 3 -TPD, H 2 -TPR, HRTEM and XPS. Superior catalytic performance was observed over the NiMo/MA-S-2Ga catalyst due to the moderate interaction between the active metals and the supports; the superior morphology for Ni promoted MoS 2 crystals, the highest sulfidation degree, the largest proportion of the NiMoS phase and the enhanced hydrogenation activity caused by the introduction of Ga species.
研究领域:
催化材料
·
化学工程
·
能源化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2024
·
IF 3.5
Dong Weinan,Qiu Xuehong,Zhao Weisong,Guo Bao,Jiang Kaixi,Chiou Mong-Feng,Li Anpeng
In this study, the occurrence state and distribution characteristics of gallium (Ga) in zinc refinery residue were investigated by dilute acid pre-washing to enrich Ga in zinc refinery residue, followed by silane coupling agent pretreatment and epoxy resin curing, and then analyzed using scanning electron microscopy, focused ion beam micro-slicing technique and transmission electron microscopy. The acid washing increased the mass ratio of Ga from 0.92% to 2.12%. Energy-dispersive spectroscopy and select area electron diffraction revealed that Ga occurred as tiny ring-like particles of gallobeudantite (a Pb-jarosite) that intimately envelop the previously formed K-jarosite fine-grained inclusions. Density functional theory calculations showed that the interplanar spacings of the new phase formed after Ga substitution for Fe in Pb-jarosite (3.413 Å and 5.505 Å) were in good agreement with the actual measured values, further confirming that Ga substitution for Fe in Pb-jarosite was achieved. The kinetical model explains the formation of multiple phases during precipitation in the treatment of zinc leaching solution. Compared to existing studies, this work reveals the spatial distribution of gallium with higher resolution and jointly determines the gallium-containing phases through experimental analysis and simulation calculations. This microanalytical method enhances the understanding of Ga species formation during zinc refining, aiding in their distribution control and process optimization. Graphical abstract
研究领域:
材料科学
·
冶金工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
·
2024
·
IF 4.7
Zhi-peng XU,Zuo-wei LIU,Xue-yi GUO,Dong LI,Ming-jin ZOU,Qing-hua TIAN
A process for gallium recovery by cyclone electrowinning was proposed to inhibit concentration polarization and improve current efficiency (CE). The diffusion coefficient of GaO 2 − in 120 g/L NaOH solution was determined to be 1.65×10 −7 cm 2 /s by electrochemical study. The effect of various parameters on gallium electrowinning was investigated, and the optimum conditions were determined as: titanium cathode, current density of 750 A/m 2 , gallium concentration of 39.9 g/L, NaOH concentration of 120 g/L, and circulation flow of 200 L/h. Under these conditions, the CE and gallium recovery of electrowinning were 47.9% and 90.2%, respectively. The precipitated gallium can be easily separated from the cathode, and the final purity of gallium after washing was 99.993%. The energy consumption (EC) of gallium cyclone electrowinning was about 9048 kW·h/t. Overall, it is suggested that cyclone electrowinning is a promising process for gallium production with high CE and low EC.
研究领域:
冶金工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）