查找使用阿拉丁产品的科研文献

Lysozyme-Functionalized PVA/CMC/β-Cyclodextrin/Pectin Hydrogel Films for Strawberry Preservation and Flexible Sensing

A multifunctional hydrogel film, denoted as PCDGPL, was developed for strawberry preservation, and its prospective flexible-sensing capability was evaluated. Distinct from previous systems centered on colorimetric freshness indication or chemically/photocrosslinked sensing networks, PCDGPL employs a physically crosslinked, freeze-thawed PVA/CMC/pectin/β-CD matrix to couple lysozyme-associated antibacterial preservation with NaCl-enabled tensile and compressive deformation responses; a full-formulation-minus-β-CD control further isolated the network-modulating contribution of β-CD. The hydrogel network was proposed to be stabilized by freeze–thaw-induced PVA physical junctions, together with multiple hydrogen-bonding interactions among CMC, pectin, and β-cyclodextrin. Glycerol improved flexibility and moisture retention, NaCl provided ionic conductivity, and lysozyme incorporation contributed to the antibacterial activity of the film. The optimized PCDGPL film showed balanced mechanical properties, stable cyclic tensile/compressive behavior, and reliable strain-dependent resistance responses under stretching and compression. It also exhibited effective antibacterial activity againstEscherichia coliandStaphylococcus aureuswith good cytocompatibility. In strawberry preservation tests, PCDGPL reduced weight loss to approximately 2.5% and decay rate to 15%, while maintaining approximately 97% of the initial firmness after 10 days. This work provides a promising hydrogel-based active packaging platform for strawberry preservation, together with a prospective capability for mechanical deformation sensing.

Nano-ZnO-Crosslinked Pectin/CMC Film with Enhanced Hydrophobicity and UV-Blocking for Blueberry Packaging

Xu Dong,Haijuan Zhu,Jianhua Zheng,Zhongliang Wang,Sihang Zhang

Developing a biodegradable film with integrated mechanical robustness and multifunctionality remains a significant challenge for sustainable food packaging. Herein, a pectin/carboxymethyl cellulose composite film (PNZxC) incorporated with zinc oxide nanoparticles (ZnO) was fabricated via a solution casting method to achieve the synergistic enhancement of structural and functional properties. ZnO exhibits dual functionality within the polymer matrix, serving both as a reinforcing filler and as a coordination interaction node via interactions with carboxyl groups. At an optimal loading, the PNZ2C film demonstrates a uniform dispersion of nanoparticles, facilitating the development of a dense network structure and enhancing intermolecular interactions. Consequently, the film showed reduced water vapor and oxygen permeability, attributable to the formation of tortuous diffusion pathways, together with increased surface hydrophobicity and a significantly improved tensile strength of 25.4 MPa. Enhanced thermal stability and excellent UV-blocking performance were also achieved. Notably, the optimized film demonstrated superior preservation performance in blueberry storage, effectively reducing moisture loss and delaying quality deterioration compared with the control. These findings provide new insights into the structure–property relationships of ZnO–polysaccharide nanocomposite systems and highlight a viable strategy for designing high-performance, biodegradable packaging materials with integrated multifunctionality.

Synergistic mechanism of green corrosion inhibitors COS and CMC-Na in Co electrochemical mechanical polishing

Chunlin Cai,Min Zhong,Meirong Yi,Xiaobing Li,Jianfeng Chen,Wenhu Xu

Electrochemical mechanical polishing (ECMP), through the introduction of electric field, promotes the chemical reaction during polishing. However, the addition of electric field will accelerate the oxidative corrosion, at this time the effective corrosion inhibitor must be added in the polishing solution. Nevertheless, most traditional corrosion inhibitors are toxic and inhibition efficiency is low. In order to meet this technical challenge, this paper investigates the effect of two green corrosion inhibitors, chitosan oligosaccharide (COS) and carboxymethylcellulose sodium (CMC-Na), on Co ECMP, and compares them with the traditional inhibitor TAZ. The results show that when COS and CMC-Na are added at the same time, the polished Co surface quality can be greatly improved, and the surface roughness decreases by 94.6 %. It indicates that adding COS and CMC-Na simultaneously can play the best corrosion inhibition effect and achieve the best surface quality. The synergistic behavior and action mechanism of COS/CMC-Na are analyzed by polishing experiments, static corrosion, electrochemical tests, XPS, and AFM. This study provides a reference for the development of green polishing solutions for Co ECMP.

Graphene Oxide-Modulated CMC/PVA Films with on-Demand Shape Recovery and Self-Healing Performance

Changdong Ju,Huabo Huang,Xianghua Yu,Jiayou Ji,Liang Li

With the advancement of artificial intelligence technologies, shape-memory polymers (SMPs) have attracted significant research interest due to their remarkable environmental responsiveness. However, conventional SMPs are limited to single-stimulus responsiveness and constrained performance, failing to meet practical application demands. This study develops a novel shape-memory carboxymethyl cellulose (CMC) and polyvinyl alcohol (PVA) composite film modulated by graphene oxide (GO) with multi-stimuli responsive capabilities and water-assisted self-healing properties. The introduction of GO significantly enhances the mechanical properties, and provides efficient swelling-resistant ability and thermal conversion efficiency of the composite film, endowing it with on-demand shape-memory performance under thermal and water stimulation. It can achieve a shape fixation rate of 94.45% and a recovery rate of 97.22%. Meanwhile, the shape-memory behaviors can be precisely tailored by modulating the content of GO and PVA as well as interfacial interactions. Furthermore, the composite films achieve efficient water-triggered self-healing with a remarkable 90.6% recovery efficiency, which is attributed to their inherent hydrophilic nature and dynamic physical crosslinking architecture. This research demonstrates a novel strategy for creating stimuli-adaptive and shape-memory materials, providing a pivotal platform for their application in flexible actuation devices and intelligent medical systems.

Water-swollen carboxymethyl chitosan (CMC) /polyamide (PA) membranes with octopus-branched nanostructures for CO2 capture

Nan Li,Zhi Wang,Jixiao Wang

Developing efficient membrane technology for CO 2 capture has aroused wide interest for environment conservation and emission reduction. Developing facilitated transport membranes is a potential strategy for improving CO 2 permeance and CO 2 /N 2 selectivity synchronously, based on the reversible reactions among carriers and CO 2 molecules. The reaction activity can be optimized by tuning the carrier mobility due to the enhanced water-swelling capacity. Here, thin-film composite (TFC) membranes containing water-swelling carboxymethyl chitosan (CMC) chains were prepared via interfacial polymerization process, aiming to improve CO 2 separation performance. As-prepared TFC membranes with different CMC loading have exhibited different Turing nanostructures , such as corrugated structures, octopus-branched structures and nodular structures. Water can enhance the activity of carriers in reversible reaction for facilitated transport membranes. TFC membranes with CMC have exhibited the enhanced water-swelling capacity, showing high CO 2 permeance of 1278 GPU together with CO 2 /N 2 selectivity of 89. This work put forward a simple and effective method to tune the membrane structure and enhance the facilitated transport.

Establishment of H1R-SNAP-tag/CMC and screening for anti-allergic active ingredients targeting H1R

Zhang Quan,Jiang Yuhan,Chen Wenhao,Wang Jinjin,Zhang Xinchi,Wang Yuan,Xu Zhuoyan,Dong Hengtao,Han Shengli

In this study, a novel cell membrane chromatography (CMC) model was developed to discover Histamine H1 receptors (H 1 R) targeted anti-allergic drugs for specific screening and ligand-receptor interaction analysis by SNAP-tagged H 1 R fusion protein conjugation and BG-modified silica gel. Allergic diseases (ADs) are prevalent pathological conditions arising from immune dysregulation, which significantly compromise patient quality of life across multiple domains, while traditional Chinese medicines (TCMs) are widely used to treat ADs. H 1 R plays a pivotal role in the pathogenesis of allergic diseases and acts as an attractive target for therapeutic intervention. Although antihistamines are the first-line therapy for ADs, their clinical utility is limited by side effects. Consequently, a novel screening method for active components targeting H 1 R in TCMs is crucial for the research and discovery of novel anti-allergic lead compounds. In the current study, the H 1 R-SNAP-tag cell membrane chromatography (H 1 R-SNAP-tag/CMC) column was prepared with outstanding specificity, selectivity, and reproducibility by chemically immobilizing H 1 R overexpression cell membranes to the BG-silica gel (BG-SiO 2 ) using the SNAP-tag technology. The H 1 R-SNAP-tag/CMC-HPLC-MS system was investigated using the H 1 R antagonist Clemastine fumarate and the results showed that the system was a reliable model for screening potential anti-allergic compounds from TCMs. From an Iris tectorum Maxim. ( I. tectorum ) extract, six H 1 R-binding compounds were identified: tectoridin, iristectorin A, iridin, tectorigenin, irigenin, and irisflorentin. Frontal analysis and molecular docking confirmed their affinity for H 1 R, while subsequent in vivo and in vitro pharmacological assays preliminarily validated their anti-allergic efficacy. Graphical abstract

Superabsorbent nanocomposite hydrogels made of carboxylated cellulose nanofibrils and CMC-g-p(AA-co-AM)

Yiming Zhou,Shiyu Fu,Liangliang Zhang,Huaiyu Zhan

Superabsorbents based on carboxylated cellulose nanofibrils (CCNFs) and carboxymethyl cellulose-g-poly(acrylic acid-co-acrylamide) were synthesized. A series of experiments were performed to evaluate the influence of factors such as CCNFs amount, solution pH, temperature, salt solution type and concentration on the swelling behaviors of the hydrogels. The water uptake of the hydrogels strongly depended on the CCNF content, the swelling capacity in distilled water increased dramatically from 245.8 to 458.7   g/g with the addition of CCNFs up to 2.5   wt%. Furthermore, the incorporation of CCNFs improved salt resistance properties of the hydrogels with slower deswelling rate and higher water retention capacity at deswelling equilibrium. Besides, the CCNF nanocomposite hydrogels presented better responsive behavior in relation to pH presence and showed an increase in water retention capacity at various temperatures. Fourier transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM) were employed to examine the structure and morphologies of the prepared superabsorbent hydrogels.

Synergistic effects of guanidine-grafted CMC on enhancing antimicrobial activity and dry strength of paper

Kai Liu,Yaoguang Xu,Xinxing Lin,Lihui Chen,Liulian Huang,Shilin Cao,Jian Li

In order to improve the strength property and antimicrobial activity of paper simultaneously, we prepared a novel multifunctional agent based on carboxymethyl cellulose (CMC) by a simple two-stage method. The first stage was the oxidation of CMC to obtain the dialdehyde CMC (DCMC), and the second stage was the graft of guanidine hydrochloride (GH) onto DCMC to obtain DCMC-GH polymer. The strength property and antimicrobial activity of DCMC-GH-coated copy paper have been studied by the tensile test and inhibition zone method, respectively. The results showed that the dry strength index could increase about 20% after the paper was coated with DCMC-GH. The coating of DCMC-GH on paper also resulted in excellent antimicrobial activities against Escherichia coli and Staphylococcus aureus , and the inhibition zone became larger as the GH content grafted on DCMC increased. The novel DCMC-GH polymer would be a multifunctional coating agent for food packaging paper.

A novel amphiphilic fluorescent probe BODIPY–O-CMC–cRGD as a biomarker and nanoparticle vector

Tingting Zhu,Ji Xiong,Zhongbo Xue,Yu Su,Fengnan Sun,Ran Chai,Jialiang Xu,Yaqing Feng,Shuxian Meng

Fluorescent probes have been demonstrated to be promising candidates as biomarkers and biological carriers. Our study focuses on the development of a novel amphiphilic fluorescent probe with good photostability, high water solubility, excellent specificity and promising loading capability for tumor diagnosis and treatment. At first, BODIPY dye and O-carboxymethyl chitosan were prepared via a chemical reaction. Then, the prepared BODIPY dye and cRGD were bonded to O-carboxymethyl chitosan successively via an acylation reaction. Finally, we obtained the desired amphiphilic fluorescent probe: BODIPY–O-CMC–cRGD, which was based on the fluorescence resonance energy transfer (FRET) principle for selective visualization of tumors in vitro. Through a series of experiments, we found that this fluorescent probe possessed better fluorescence characteristics and tumor targeting properties. Simultaneously, by self-assembly, the amphiphilic probe encapsulated the other flexible structure of BODIPY2 and the rigid structure of porphyrin, which formed distinct nanoparticles with different particle sizes. Hence, we could observe different phagocytosis processes of the two nanoparticles in the tumor cells via the fluorescence of dyes by confocal laser scanning microscopy. Therefore, the results suggest that the fluorescent probe has advantages in tumor detection, and the constructed tumor-specific nanoparticles show high clinical potential to be utilized not only in visual and precise diagnosis but also in excellent drug delivery for tumor treatment. Henceforth, we will prepare new targeted and visualized pharmaceuticals by replacing BODIPY2 and porphyrin with antineoplastic drugs for future tumor treatment.

Production and characterization of CMC-based antioxidant and antimicrobial films enriched with chickpea hull polysaccharides

Hafiz Muhammad Saleem Akhtar,Asad Riaz,Yahya Saud Hamed,Mohamed Abdin,Guijie Chen,Peng Wan,Xiaoxiong Zeng

In the present study, polysaccharides from chickpea hull (CHPS) were incorporated into carboxymethyl cellulose (CMC) for the development of CMC-based films. The physical and mechanical properties, color, transmittance, antioxidant and antimicrobial activities were investigated, and differential scanning calorimetry (DSC), Fourier transform-infrared (FT-IR) spectroscopy and thermogravimetric analysis (TGA) were applied to study the potential interaction, structure and thermal stabilization of the prepared films. The results revealed that some physical and mechanical properties of films, like moisture content, elongation at break and water vapor permeability, were decreased. While thickness, swelling ratio, water solubility and tensile strength were significantly increased ( p  < 0.05) compared with control film. Furthermore, the films exhibited potential antioxidant effects on DPPH and ABTS free radicals. The results of scanning electron microscopy showed rough and heterogeneous morphology for CMC-CHPS films while control film exhibited smooth, homogenous and compact structure. FT-IR results reflected good interaction of chemical groups and bonds between CMC and CHPS. DSC results showed that glass transition temperature increased significantly ( p  < 0.05) from 82.68 to 90.39 °C compared with control of 78.21 °C. Thermal stability of all films was improved, indicating that the films could be used as biocomposite materials for packaging of food products.

Selective flotation of rutile from almandine using sodium carboxymethyl cellulose (Na-CMC) as a depressant

Richard M. Kasomo,Hongqiang Li,Huifang Zheng,Qian Chen,Xiaoqing Weng,Akisa D. Mwangi,Wu Ge,Shaoxian Song

In this paper, Na-CMC was studied as a depressant for almandine during flotation separation of rutile using cationic surfactant, octadecyl amine polyoxyethylene ether (AC1815) as a collector. Results of micro-flotation studies suggested that Na-CMC was considered as a selective depressant for almandine. Zeta potential and X-ray Photoelectron Spectroscopy (XPS) were used to elucidate the interaction mechanism between the minerals (rutile and almandine) and Na-CMC. The XPS analysis results show that there was both the chemical and hydrogen bonding in the interaction between almandine and Na-CMC. Zeta potential measurements indicate that, the adsorption of carboxylic groups on the almandine ferrous active sites, takes place with chemisorption which in turn depressed the almandine floatability. Contact angles results on the other hand shows that the floatability of almandine was adversely affected after being treated with Na-CMC, while the same depressant did not have any pronounced negative effect on the floatability of rutile.

Nanoencapsulation of zeaxanthin extracted from Lycium barbarum L. by complex coacervation with gelatin and CMC

Jiaying Zhang,Guoliang Jia,Zhao Wanbin,Jiang Minghao,Yulong Wei,Jingyi Hao,Xiaolin Liu,Zhilin Gan,Aidong Sun

This study developed nanocapsules by complex coacervation between gelatin (G) and sodium carboxymethyl cellulose (CMC) for the encapsulation of zeaxanthin extracted from Lycium barbarum L. The optimum pH and G-CMC mass mixing ratio were determined by analysis of the zeta potential , turbidity, morphology, particle size distribution, complex coacervate yield, emulsification stability index (ESI) and emulsification activity index (EAI). The formation mechanism of the G-CMC coacervates was examined by fourier transform infrared spectroscopy (FTIR) analysis. Moreover, the morphology, particle size distribution, thermal properties and in vitro simulated gastrointestinal digestion of zeaxanthin nanocapsules were investigated. The results showed that the optimum mass mixing ratio of G-CMC was 9:1 (w/w) with an optimum pH of 4.50. FTIR analysis confirmed the electrostatic interaction between the –NH 3 + of G and the -COO - of CMC in the formation of G-CMC complex coacervates. Thermal gravimetric analysis (TGA) showed that nanoencapsulation could enhance the thermal stability of zeaxanthin. In vitro simulated gastrointestinal digestion experiments showed that zeaxanthin had good sustained release performance in simulated gastric fluid (SGF) and large amounts of zeaxanthin were released in simulated intestinal fluid (SIF).