ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2022
·Vol. 29
·期 35
·53509-53521
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IF 5.19
Peng Xiaoying,Zheng Jiahao,Wang Jinsong,Xiang Chao,Wang Rui
In this study, the potassium copper ferrocyanide-functionalized hollow mesoporous silica spheres was successfully prepared. SEM, FTIR, XRD, EDS, and XPS techniques were used to characterize the structure of materials before and after functionalization. The synthesized functionalized hollow mesoprous silica was applied to remove cesium from aqueous solution. The applicability of the adsorbent for the removal of cesium ions was assessed and the effective parameters such as solution pH, contacting time, initial Cs + concentration, and competitive ions effect were evaluated systematically under the batch mode. The experimental results showed that the adsorbent exhibited high Cs + selectivity even in the highly concentrated coexisting ions solution, which makes them to be used as potential adsorbents for the removal of cesium from nuclear wastewater or contaminated groundwater.
研究领域:
材料科学
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环境科学
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核废料管理
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产品关联
DOI
PubMed
高影响因子
TALANTA
·
2015
·
IF 3.545
Yange Sun,Xingxing He,Jian Ji,Min Jia,Zhouping Wang,Xiulan Sun
This paper presents a new electrochemical DNA biosensor constructed using a substrate electrode composed of a novel nanocomposite material prepared using gold nanoparticles (Au-NPs) and multiwalled carbon nanotubes (MWCNTs) and further modified with an Au electrode (AuE), which was used as the substrate electrode. A single-stranded DNA (ssDNA) probe was immobilized on the Au-NPs/CS–MWCNTs/AuE electrode by means of facile gold–thiol affinity, which resulted in hybridization with the target ssDNA sequence. Hybridization reactions were assessed by using the reduction peak current of methylene blue (MB) as an electrochemical indicator. The advantages of the nanomaterials were found to include high surface area, favorable electronic properties, and strong electrocatalytic activity . The amount of ssDNA adsorbed on the electrode surface was increased and the electrochemical response of MB accelerated. The differential pulse voltammetric responses of MB were in line with the specific target ssDNA sequence within the concentration range 1.0×10 −15 –1.0×10 −8 M with the detection limit 3.3×10 −16 M (3 σ ). In the colony forming unit (CFU) we were able to detect 10 CFU mL −1 of Staphylococcus aureus in the tap water, achieving good discrimination ability between one- and three-base mismatched ssDNA sequences. The polymerase chain reaction (PCR) amplification products of S. aureus nuc gene sequence were also detected with satisfactory results.
研究领域:
生物化学
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纳米技术
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电化学
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微生物学
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Xin Liu,Jihui Wang,Wenbin Hu
The superparamagnetic Fe 3 O 4 /CS/inhibitor nanocomposite was synthesized by using ionic gel method with Fe 3 O 4 as superparamagnetic core, chitosan as nanocarrier and molybdate (MoO 4 2− ) and benzoate (C 6 H 5 COO − ) working as loaded inhibitors. The morphology, structure and magnetic property of nanocomposite were characterized by transmission electron microscopy , X-ray diffraction, Fourier transform infrared spectroscopy and vibrating sample magnetometer . The release behavior of nanocomposite with and without external magnetic field (“no MF” mode and “MF ON” mode) was conducted by UV–vis spectroscopy, and the corrosion inhibition performance of nanocomposite for carbon in 3.5% NaCl solution was investigated by polarization curve and electrochemical impedance spectrum methods. The results show that the obtained Fe 3 O 4 /CS/inhibitors was in a well-defined core-shell structure with MoO 4 2− and C 6 H 5 COO- loaded flake-like chitosan shell stacking closely to Fe 3 O 4 surface. Under no MF mode, the release behavior of nanocomposite was mainly ion exchange and Fickian diffusion mechanism. Under MF ON mode, the swelling of polymer chains and diffusion between magnetic nanoparticles were involved apart from the ion exchange and Fickian diffusion mechanism. With the addition of nanocomposite inhibitors in NaCl solution, the charge transfer resistance and inhibition efficiency of steel increased firstly and then decreased with the prolonging of immersion time. The highest inhibition efficiency of nanocomposite inhibitors in NaCl solution under on MF and MF ON mode was located in 30 min and 90 min respectively. The inhibition of nanocomposite for carbon steel in NaCl solution is resulting from the reduction of aggressive Cl- concentration in the solution due to the ion exchange between Cl- ions in solution and MoO 4 2− and C 6 H 5 COO- ions in the nanocomposite, and the formation of ferric/ferrous molybdate, ferric/ferrous benzoate and basic ferric benzoate inhibition films on steel. This novel as-prepared composite owns superior loading capacity of inhibitors and its preparation process is especially simple relative to other nanocomposites in previous reported works.
研究领域:
材料科学
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腐蚀工程
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纳米技术
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电化学
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产品关联
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2025
·
IF 3.6
Ling Peng,Yusong Pan,Qianqian Liu,Cuilian Wei,Run Huang,Wenjie Luo,Xiuling Lin,Jun Tao,Yinghai Xie
Spinal cord injury (SCI) is a common disease worldwide. Tissue engineering scaffolds are considered a promising strategy for SCI treatment, but their efficacy is significantly limited by the local abundance of MSC (mesenchymal stem cell) and a highly inflammatory microenvironment. In this study, a multifunctional composite scaffold of polycaprolactone/chitosan (PCL/CS) loading polydopamine (PDA)-coated nerve growth factor (NGF) loaded onto was prepared using a freeze-drying method. The PCL/CS composite scaffold exhibited tunable degradation properties and excellent biocompatibility. The PDA coating demonstrated potent free radical scavenging capabilities, achieving clearance rate of 90.65%, 77.53%, and 60.77% for DPPH, H2O2, and ·OH radicals, respectively. Remarkably, the scaffold effectively reduced intracellular ROS levels within 24 h under oxidative stress conditions. Flow cytometry revealed rapid cellular internalization, with the FITC-labeled PC-5-PDA group exhibiting a 99.87% FITC+ rate within 12 h. NGF release from the scaffold induced robust neuronal differentiation of PC-12 cells, as evidenced by a 58.1% increase in neurite length (from 104.77 μm at day 3 to 165.66 μm at day 4) and upregulated expression of microtubule-associated protein 2 (MAP2). These findings demonstrate the dual functionality of the scaffold, which is effectively modulating the post-SCI inflammatory microenvironment while promoting neural regeneration.
研究领域:
生物材料
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组织工程
·
神经再生
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抗氧化治疗
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干细胞生物学
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产品关联
DOI
PubMed
高影响因子
DRUG DELIVERY
·
2023
·
IF 6
Xiaoyan Xu,Tianhao Zhou,Xudong Wei,Xuelian Jiang,Jiyan Cao
Although surgery-based comprehensive therapy is becoming the main approach to treat laryngeal cancer, recurrence, metastasis, radiotherapy resistance and chemotherapy tolerance are still the main causes of death in patients. Targeted inhibition of laryngeal cancer stem cells has been considered as the consensus to cure laryngeal cancer. Our previous study has confirmed proto-oncogene Bmi-1 as a key regulator for self-renewal of laryngeal cancer stem cells. Targeted knockdown of Bmi-1 gene effectively inhibited the self-renewal and differentiation of laryngeal cancer stem cells, leading to the promoted sensitivity to chemotherapy including paclitaxel. However, due to off-target effects and quick degradation of the naked Bmi-1-RNAi small RNA oligo by nuclease in body fluids, it is urgently needed to develop a tumor-targeted delivery system with a protective shell. In this study, we designed and synthesized cRGD peptide-modified chitosan-polyethylene glycol slow-release nanoparticles (mPEG-CS-cRGD/Bmi-1RNAi-PTX) containing Bmi-1RNAi siRNA oligo and paclitaxel, which showed spherical in shape, 200 nm diameter in size, low cytotoxicity, strong DNA wrapping, resistance to nuclease degradation and high transfection efficiency to cells. Functional analysis indicated significant suppression of cell proliferation and migration and induction of apoptosis by the nanocomplex in laryngeal cancer cells in vitro. By application to the mouse model with laryngeal cancer, the nanocomplex inhibited tumor growth significantly in vivo. In addition, cRGD peptide, paclitaxel and Bmi-1 siRNA in the nanoparticles showed synergistic effects to suppress laryngeal cancer stem cells. In conclusion, this study not only developed a laryngeal tumor-targeted chemotherapeutic system, but also demonstrated a Bmi-1 RNAi-based chemotherapeutic strategy to inhibit cancer stem cells, having strong potential to treat laryngeal cancer patients suffering therapy resistance and/or tumor recurrence.
研究领域:
肿瘤学
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纳米技术
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分子生物学
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药学
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产品关联
DOI
PubMed
高影响因子
BIOELECTROCHEMISTRY
·
2021
·
IF 5.373
Jintao Liang,Xiaohang Shi,Huafu Feng,Min Chen,Wenzhan Li,Junxiang Lai,Weipeng Hu,Guiyin Li
In this paper, a novel silicon-based light-addressable potentiometric sensor (LAPS) has been designed for the detection of 1,5-anhydroglucitol (1,5-AG) in human serum. Reduced graphene oxide-chitosan-ferrocene (RGO-CS-Fc)/AuNPs nanohybrids and pyranose oxidase (PROD) enzyme is used to fabricate biological sensitive membrane unit by layer-by-layer assembly technology. When a bias voltage is provided to the LAPS system, the catalytic oxidation reaction between 1,5-AG and PROD to produce H 2 O 2 . The by-product H 2 O 2 can oxidize Fc(Fe 2+ ) ions in RGO-CS-Fc nanohybrids into Fc(Fe 3+ ) ions, which cause the potential of the sensitive membrane surface to change and the potential shift of I-V curve will generate a corresponding offset response. Under the optimal conditions, the potential shift of the LAPS is linearly related to the concentration of 1,5-AG at 10 µg·mL −1 –350 µg·mL −1 with the correlation coefficient of 0.97414. The sensitivity is 0.44273 mV/µg·mL −1 and the lowest detection limit is 10 µg·mL −1 . In addition, the biosensor showed good specificity, acceptable stability and satisfactory recovery rates (91.28%-107.66%), which would be a potential testing methods in actual clinical samples.
研究领域:
生物医学工程
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分析化学
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纳米技术
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生物传感器
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Xinyan Wang,Yuting Zhang,Jian Zhang,Chengpeng Shao,Jiaxing Yang,Yuning Zhang,Ruoyi Li,Zheng Xing
In this study, a Z-type heterojunction photocatalyst CoWO 4 /CS/BiOCl-10 was constructed by hydrothermal synthesis for the efficient removal of norfloxacin (NOR) contaminants in water. X-ray photoelectron spectroscopy (XPS) combined with Fourier transform infrared spectroscopy (FT-IR) confirmed that the hydroxyl group in the chitosan (CS) molecule was bonded with the oxygen atom on the surface of CoWO 4 through hydrogen bonding to form a directional charge transport channel, which greatly improved the photocatalytic degradation efficiency of CoWO 4 /CS/BiOCl-10, and the degradation rate was as high as 98.30 % within 90 min under 300 W xenon lamp irradiation. Optoelectronic measurements show that the interfacial potential difference drives electrons to migrate along the Z-path. Density functional theory (DFT) and liquid chromatography-mass spectrometry (LC-MS) were used to identify intermediates in the NOR degradation process, revealing the degradation pathway of NOR through piperazine ring cleavage and defluorination. The kinetics of NOR degradation intermediates were revealed using two-dimensional correlation spectroscopy (2DCOS) techniques. Rice seed germination experiments have shown that the degraded NOR solution is virtually non-toxic, greatly reducing the environmental impact. This study provides a new strategy for the development of efficient photocatalytic systems through the synergistic regulation mechanism of hydrogen bonding and heterojunction.
研究领域:
环境科学
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材料科学
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光催化
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水处理
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化学工程
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光谱学
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毒理学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Ran Ran,Wei Zhu,Guoliang Zhang,Lei Wang,Gongying Wang,Jie Li
The loaded acid–base bifunctional catalysts exhibit good catalytic performance in the synthesis of methyl methacrylate via aldol condensation of methyl propionate with formaldehyde, but they still suffer from deactivation caused by coke deposition. In this paper, coke deposition as well as consequential deactivation behavior of Cs/SiO2 catalyst loaded with various amounts of Al was investigated under different reactant compositions by using nuclear magnetic resonance, thermogravimetric, Brunauer–Emmett–Teller, and Raman analysis. As a result, coke on the catalyst was characterized by amorphous coke deposition, which was mainly composed of polycyclic aromatic hydrocarbons and aliphatic substances. Al added to the 10Cs/SiO2 catalyst significantly reduced the amount of coke deposition and inhibited the C/H ratio of coke. Appropriate amounts of Al and reactant compositions could ultimately increase the stability of the catalyst. Moreover, the kinetics of coke deposition observed on the Al–Cs/SiO2 catalyst was studied. It was found that the Voorhies equation modified using the variables of reaction temperature and reactants composition could accurately forecast coke accumulation on the 3.5Al-10Cs/SiO2 catalyst under specific conditions.
研究领域:
催化化学
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化工工程
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物理化学
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产品关联
DOI
高影响因子
Catalysts
·
2025
·Vol. 15
·期 7
·694
·
IF 4
Ziyan Mi,Huayun Long,Yuhua Jia,Yue Ma,Cuilan Miao,Yan Xie,Xiaomei Zhu,Jiahui Huang
The development of non-noble metal catalysts for gas-phase propylene epoxidation with H2/O2remains challenging due to their inadequate activity and stability. Herein, we report a Cs+-modified Ni/TS-1 catalyst (9%Ni-Cs/TS-1), which exhibits unprecedented catalytic performance, giving a state-of-the-art PO formation rate of 382.9 gPO·kgcat−1·h−1with 87.8% selectivity at 200 °C. The catalyst stability was sustainable for 150 h, far surpassing reported Ni-based catalysts. Ni/TS-1 exhibited low catalytic activity. However, the Cs modification significantly enhanced the performance of Ni/TS-1. Furthermore, the intrinsic reason for the enhanced performance was elucidated by multiple techniques such as XPS, N2physisorption, TEM,29Si NMR, NH3-TPD-MS, UV–vis, and so on. The findings indicated that the incorporation of Cs+markedly boosted the reduction of Ni, enhanced Ni0formation, strengthened Ni-Ti interactions, reduced acid sites to inhibit PO isomerization, improved the dispersion of Ni nanoparticles, reduced particle size, and improved the hydrophobicity of Ni/TS-1 to facilitate propylene adsorption/PO desorption. The 9%Ni-Cs/TS-1 catalyst demonstrated exceptional performance characterized by a low cost, high activity, and long-term stability, offering a viable alternative to Au-based systems.
研究领域:
催化化学
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化学工程
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材料科学
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多相催化
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绿色化学
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产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2023
·
IF 12.6
Huanhuan Li,Wenhui Geng,Zhixiong Qi,Waqas Ahmad,Suleiman A. Haruna,Quansheng Chen
In this work, a stimuli-responsive SERS biosensor was fabricated for tetracycline (TTC) by “signal-on” strategy using (EDTA)-driven polyethyleneimine grafted calcium carbonate ( [email protected] 3 ) microcapsule and chitosan-Fe magnetic microbeads ( [email protected] ). Initially, aptamer conjugated magnetic-bead [email protected] @Apt with superparamagnetism and excellent biocompatibility was employed as capture probe, which facilitated the rapid and easy magnetic separation. Subsequently, the PEI cross-linked layer and aptamer network layer were constructed onto the outer layer of CaCO 3 @4-ATP microcapsule to form sensing probes ( [email protected] 3 @ [email protected] ) via the layer-by-layer assembly method. In the presence of TTC, a sandwich SERS-assay was exploited by aptamer recognition induced target-bridged strategy. When the solution of EDTA was added, the core layer of CaCO 3 would be dissolved quickly, destroying the microcapsule to release 4-ATP. The released 4-ATP could be quantitatively monitored by dripping the supernatant onto the [email protected] SERS platform, resulting in a strong Raman “signal-on”. Under the optimal conditions, a good linear relationship was established with a correlation coefficient ( R 2 ) of 0.9938 and a LOD of 0.03 ng/mL. Additionally, the application capacity of the biosensor to detect TTC was also affirmed in food matrixes, and the results were consistent with the standard ELISA method ( P > 0.05). Hence, this SERS biosensor affords extensive application prospects for TTC detection with multiple merits such as high sensitivity, environment friendliness, and high stability.
研究领域:
分析化学
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环境科学
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食品安全
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生物传感器
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Yuqi Wang,Yi He,Hongjie Li,Jing Yu,Liyun Zhang,Li Chen,Yang Bai
Filtration membranes, with excellent anti-fouling capability, are ideal for actual oily sewage treatment, but the absence of a pre-hydration procedure is still a challenge. In this study, we demonstrated an environmentally friendly, and economical route to solve this problem by depositing chitosan (CS)-cellulose nanocrystals (CNCs) multilayer on stainless steel mesh (SSM) via simple layer-by-layer (LBL) self-assembly method. Due to the chemical structure , the CNCs have a large number of hydrophilic groups that are tightly bound to the surface, so the CS-CNCs multilayer modified mesh can maintain their strong surface hydration ability in air or oil, and will not be contaminated by crude oil even in a dry state. Besides, the CS-CNCs multilayer modified mesh exhibits superamphiphilic, underwater superoleophobic, and under-oil superhydrophilic functions. Moreover, the modified mesh also shows high rejection rate for crude oil/water mixture (99.92%) and diverse oil-in-water emulsions (>99.58%). What's more, the mesh has excellent reusability and chemical stability. The outstanding advantages in low-cost, environmental protection, biodegradability, anti-crude-oil-fouling performance, and efficient oil/water separation, endow our CS-CNCs multilayer modified mesh with great potential in complicated oily sewage purification.
研究领域:
材料科学
·
环境工程
·
化学工程
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产品关联
DOI
高影响因子
MEASUREMENT
·
2025
·
IF 5.6
Jiangrong Hou,Liang Guo,Bingzhi Yan,Shuxian Gao,Chuxiao Sun,Yanpei Xu,Qi Wang
This paper introduces a wireless passive humidity sensor based on a molybdenum disulfide (MoS 2 ) nanoflower and chitosan (CS) composite material, designed to address the limitations of traditional humidity sensors, including weak response, complex structure, and high cost, particularly in extreme humidity environments. The innovative MoS 2 /CS composite dielectric layer was developed by leveraging the high specific surface area and active sites of MoS 2 , in conjunction with the hydrophilicity and biocompatibility of CS. Experimental results demonstrate that an optimized composite material ratio (MoS 2 :CS = 1:20) yields an ultra-high sensitivity (660 kHz/%RH), faster response/recovery time (70 s/120 s), The device demonstrates a strong linear response within a humidity range of 40 %–60 %RH, evidenced by a linearity value of 0.98779. However, between the humidity range of 60 %–95 %RH, the resonant frequency exhibits a quintic relationship with humidity. In this range, the linearity R 2 value is 0.99656. and minimal hysteresis (approximately 3 %) across a broad humidity range (40 %–95 % RH). Furthermore, the chemical-physical synergistic adsorption mechanism of the composite material was elucidated using characterization methods such as FTIR, XPS, and SEM. Chemical adsorption (hydrogen bonding and coordination bonding) predominates at low humidity, while physical adsorption (swelling and interlayer hydration) is more prevalent at high humidity. The sensor offers several advantages, including low cost, long-term stability (no drift for 30 days), and environmental compatibility, thereby providing a high-performance solution for the Internet of Things and closed monitoring systems. This also expands the potential application of two-dimensional materials and biopolymers in the field of wireless sensing.
研究领域:
传感器与传感技术
·
材料科学
·
无线传感器网络
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环境监测
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纳米材料
·
物联网（IoT）
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）