Nature Communications
·
2023
·Vol. 14
·期 1
·1-12
·
IF 16.6
Zhou Hua,Ren Yue,Yao Bingxin,Li Zhenhua,Xu Ming,Ma Lina,Kong Xianggui,Zheng Lirong,Shao Mingfei,Duan Haohong
Electrooxidation of biomass platforms provides a sustainable route to produce valuable oxygenates, but the practical implementation is hampered by the severe carbon loss stemming from inherent instability of substrates and/or intermediates in alkaline electrolyte, especially under high concentration. Herein, based on the understanding of non-Faradaic degradation, we develop a single-pass continuous flow reactor (SPCFR) system with high ratio of electrode-area/electrolyte-volume, short duration time of substrates in the reactor, and separate feeding of substrate and alkaline solution, thus largely suppressing non-Faradaic degradation. By constructing a nine-stacked-modules SPCFR system, we achieve electrooxidation of glucose-to-formate and 5-hydroxymethylfurfural (HMF)-to-2,5-furandicarboxylic acid (FDCA) with high single-pass conversion efficiency (SPCE; 81.8% and 95.8%, respectively) and high selectivity (formate: 76.5%, FDCA: 96.9%) at high concentrations (formate: 562.8 mM, FDCA: 556.9 mM). Furthermore, we demonstrate continuous and kilogram-scale electrosynthesis of potassium diformate (0.7 kg) from wood and soybean oil, and FDCA (1.17 kg) from HMF. This work highlights the importance of understanding and suppressing non-Faradaic degradation, providing opportunities for scalable biomass upgrading using electrochemical technology.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Lili Zhang,Yan Li,Jing Gao
Haematococcus pluvialis is rich in astaxanthin ester (Ast 1 ) and free astaxanthin (Ast 2 ). The astaxanthin is natural antioxidant, and shows higher biodegradability and eco-friendly characteristics than commercial astaxanthin. However, the existing extraction technology is difficult to achieve selectively separation of Ast 1 and Ast 2 . Novel aqueous biphasic systems (ABSs) composed of ionic liquids (ILs) and deep eutectic solvents (DESs) were developed to selectively extract Ast 1 and Ast 2 . The results showed that the ABS composed of tributyloctylphosphine chloride ([P 4448 ]Cl) and choline chloride: d -fructose ([ChCl][Fru]) performed best. The yield and partition coefficient of astaxanthin was 2.35 mg·g −1 and 103.59, respectively. Moreover, Ast 1 and Ast 2 could be selectively separately with the highest coefficient of specificity of 48.31. Furthermore, the ABS maintained an excellent extraction capacity after three cycles of recycling. As compared with organic solvent extraction and prior methods, the IL-DES ABS is more efficient, recyclable, and environmentally friendly for selectively extraction of astaxanthin.
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JOURNAL OF SEPARATION SCIENCE
·
2023
·Vol. 46
·期 20
·2300384
·
IF 3.1
Zheng Jiang,Hong Wang,Miao Yu,Cheng Qu,Wei Yue,Qinan Wu
In this study, a low-cost efficient online derivatization system was developed which allows for the detection of various types of mono- and oligo-saccharides only utilizing high-performance liquid chromatography (HPLC)-ultraviolet detector (UV) system. In the proposed method, phenylhydrazine was used as the derivatization reagent and directly spiked in the mobile phase, allowing for the separation and detection of mono- and oligosaccharides in an accessible instrument system (HPLC-UV). And the online derivatization design of the proposed method has significantly reduced the potential harm of derivatization reagents to the analysts. Furthermore, critical chromatographic parameters were optimized via the Box-Behnken design strategy, culminating in the ideal response for saccharides. Finally, the methodology validation of the proposed method was conducted. The proposed method showed satisfactory linear ranges with acceptable correlation coefficients (R 2 > 0.99), outstanding accuracy (Recovery: 95.3%–105.6%), high intra-day precision (relative standard deviation [RSD]: 1.4%–7.1%) and inter-day precision (RSD: 2.0%–7.4%). The robustness and ruggedness of the proposed method were proved as the recovery values in the range of 95.0%–104.6% and 95.1%–104.8% for robustness and ruggedness, respectively. These satisfactory validation results confirm the applicability and reliability of the proposed method for the analysis of saccharides in various complex real-world samples.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2021
·Vol. 413
·期 8
·2135-2146
·
IF 4.157
Mei He,Ma Yange,Wu Huimin,Wang Xuedong
Herein, we synthesized and characterized glutathione-capped copper nanoclusters (CuNCs) using a convenient one-pot chemical reduction approach based on glutathione as capping and reducing agents. The Ce(III) induced aggregation-induced emission of CuNCs to form a CuNCs-Ce 3+ fluoroprobe due to electrostatic and coordination interactions between Ce 3+ and CuNCs. In contrast to CuNCs, the fluorescent intensities (FLs) of CuNCs-Ce 3+ were enhanced by ~ 40-fold concomitant with 20-nm blue-shift of the maximum emission, and a 3.45-fold lengthening of the average fluorescent lifetime. The FLs of CuNCs-Ce 3+ were selectively quenched at 650 nm by hydrogen peroxide (H 2 O 2 ) via the redox reaction. Based on this phenomenon, the sensitive assay of H 2 O 2 was realized, and the linear range spanned over the range of 14–140 μM. Notably, the visualization of the fluorescence quenched effect of H 2 O 2 could be easily attained. Additionally, glucose could be specifically oxidized by glucose oxidase to produce H 2 O 2 , and thus the detection of glucose was achieved according to changes in the concentrations of H 2 O 2 . Under optimized conditions, the fluorescent assay of glucose based on the CuNCs-Ce 3+ system offered the linear range of 8–48 μM with detection limit of 2.4 μM. Meanwhile, high selectivity of the as-constructed fluorescent assay allows the sensitive detection of H 2 O 2 and glucose in real-world care products and human serum samples, showing a great application potential in their conventional monitoring.
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INDUSTRIAL CROPS AND PRODUCTS
·
2021
·
IF 5.645
Lipeng Zhou,Dongting Gao,Yangyang Ma,Hongji Li,Yunlai Su,Xiaomei Yang,Tianliang Lu
Hydrolysis of cellulose to glucose is one of the most important processes for the conversion of biomass to fuels and chemicals. Besides cellulose, lignin is the third of the main components of native lignocellulose . It is essential to understand the role of lignin in the depolymerization process of cellulose using lignocellulose as raw material. Here, the role of lignin was studied by using a lignin dimer model with a β-O-4 linkage and an organsolv lignin as the additive, respectively, for depolymerization of cellulose via oxidation-hydrolysis method. The results showed that both lignin dimer model and organsolv lignin substantially promoted the oxidation of cellulose and increased the yield of glucose. 30.01% yield of glucose was given for microcrystalline cellulose in present of 10% organsolv lignin, compared to 22.64% glucose yield for pure microcrystalline cellulose. Additionally, the mechanism of the promotion effect of lignin on the oxidation of cellulose process was proposed.
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Journal of the Taiwan Institute of Chemical Engineers
·
2021
·
IF 5.876
Xin Li,Guoying Wang,Yawen Hu,Yves Iradukunda,Fenfang Luo,Kaiqiang Yi,Gaofeng Shi
Background In order to replace petrochemicals , there is an increasing demand for environmentally friendly new biochemicals, and 5-hydroxymethyl furfural is one such product. Methods In this paper, sulfonated carbon-titanium dioxide composite nanofiber tube catalyst was prepared by electrospinning and used for the dehydration of carbohydrates into 5-hydroxymethylfurfural in aqueous/ethyl acetate biphasic solution. The catalyst showed good activity in preparing of 5-hydroxymethylfurfural using fructose and glucose as raw materials, with yields of 75.47% and 42.44% of 5-hydroxymethylfurfural. In addition, the catalyst still had catalytic effect when starch and cellulose as the reactants. Significant findings Results showed that the catalytic ability of the catalyst was found to be significantly better than that of a single sulfonated carbon or titanium dioxide, at the same time, the catalyst can be used multiple times and is easy to regenerate. Besides, this study investigated the purification process of 5-hydroxymethylfurfural and finally obtained 95.34 wt.% purity of 5-hydroxymethylfurfural.
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CATALYSIS LETTERS
·
2021
·Vol. 152
·期 4
·954-961
·
IF 3.186
Shi Shengbin,Wu Yuanfeng,Liu Panli,Zhang Mengting,Zhang Zongqi,Gao Lijing,Xiao Guomin
Synthesis of 5-hydroxymethylfurfural (HMF) from carbohydrates was achieved over the homogeneous catalyst acid poly(4-styrenesulfonic acid) (PSS). The various reaction conditions like reaction temperature, reaction time, various solvent, solvent volume, and catalyst dosages were explored. The results showed that the PSS catalyst resulted in 86.8% HMF yield from fructose and 48.5% HMF yield from glucose in solvent 1-methyl-2-pyrrolidone and dimethyl sulfoxide, respectively. The catalyst has reused five cycles without obviously reduced on HMF yield, suggesting that PSS showed high catalytic activity at recycle experiment. Thus, PSS was a potential candidate for homogeneous catalyst acids and can convert carbohydrate compound into HMF conveniently. Graphical Abstract
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Journal of Cleaner Production
·
2021
·
IF 9.297
Nan Zhou,Cheng Zhang,Yang Cao,Jiahui Zhan,Jiajun Fan,James H. Clark,Shicheng Zhang
Furfural is a promising platform chemical that can be catalyzed from lignocellulose biomass. In this study, a novel micro-mesoporous carbon supported tin oxide catalyst (MC-SnO x ) was developed to convert xylose into furfural in a low sodium chloride (NaCl) concentration and acid-free biphasic system. The catalysts synthesized by annealing from 400 °C to 600 °C for 3.5h were characterized by BET, SEM, XPS , XRD , NH 3 -TPD and FTIR techniques. The factor that mostly affected the catalytic performance was the acid concentration of the catalysts, and the best catalytic performance was achieved by MC-SnO x annealed at 450 °C. Further increasing the annealing temperature can cause reduction, volatilization and aggregation of Sn species, which can finally affect acid concentration and performance of the catalyst. In addition, a synergistic catalytic effect was found between MC-SnO x and NaCl and effectivity of low concentration of NaCl indicated the potential of applying seawater or wastewater containing NaCl as a low-cost reaction solvent and NaCl source. To balance the catalytic performance, cost, equipment safety and environmental concerns, a reasonable furfural yield of 53.9% was achieved over the MC-SnO x -450 and NaCl (0.2 M) in biphasic system under mild conditions (180 °C and 20 min) with a good catalyst reusability .
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2021
·
IF 5.279
Huicui Liu,Tao Chen,Xiaoqing Xie,Xinlei Wang,Yiwen Luo,Nan Xu,Zhen Sa,Min Zhang,Zhifei Chen,Xinzhong Hu,Juxiu Li
Nonalcoholic fatty liver disease (NAFLD) is characterized by marked imbalances in lipid storage and metabolism. Because the beneficial health effects of cereal β-glucan (BG) include lowering cholesterol and regulating lipid metabolism, BG may alleviate the imbalances in lipid metabolism observed during NAFLD. The aim of our study was to investigate whether BG from highland barley has an effect on western diet-induced NAFLD in mice. Using lipidomics, we investigated the underlying mechanisms of BG intervention, and identified potential lipid biomarkers. The results reveal that BG (300 mg/kg body weight) significantly alleviated liver steatosis. Lipidomics analysis demonstrated that BG also altered lipid metabolic patterns. We were able to identify 13 differentially regulated lipid species that may be useful as lipid biomarkers. Several genes in the hepatic lipid and cholesterol metabolism pathways were also modulated. These findings provide evidence that BG ameliorates NAFLD by altering liver lipid metabolites and regulating lipid metabolism-related genes.
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ENZYME AND MICROBIAL TECHNOLOGY
·
2021
·
IF 3.493
Dong-Xu Jia,Chen-Yi Sun,Yi-Ting Jin,Zhi-Qiang Liu,Yu-Guo Zheng,Mian Li,Hong-Yan Wang,De-Shui Chen
Allulose is an epimer of d -fructose with multiple nutritional functions, which can be biologically synthesized from d -fructose employing d -allulose 3-epimerase (DAE). In this study, NCBI database mining approach was applied to screen novel DAEs, and Novibacillus thermophilus DAE (NtDAE) exhibiting a high activity of 273.9 U/(g⋅wet cell weight) was selected for investigation. NtDAE showed optimum reaction temperature and pH at 70 °C and 7.0, respectively. In the presence of Co 2+ , its activity was improved by 100.1 %, and the half-life ( t 1/2 ) values reached up to 846.3, 539.2 and 47.8 min at 40, 50 and 60 °C, respectively. Higher k cat / K m values toward d -allulose indicated that the preferred physiological substrate of NtDAE was d -allulose. The conversion yield of 500 g/L d -fructose to d -allulose at 60 °C achieved 29.7 %, and further enhanced to 51.6 % with adding 1.1 M borate. This study provided a useful guidance of further engineering and application of NtDAE for realization of industrial production of d -allulose.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Amjad Farid,Lujun Pan,Muhammad Usman,I.A. Khan,Abdul Sammed Khan,Aqrab ul Ahmad,Muhammad Javid
The combination of transition-metals with chalcogens provide a platform for developing highly sensitive and stable electro-catalyst materials possessing excellent electrochemical features regarding glucose oxidation . The growth of porous cobalt telluride (CoTe 2 ) nanosheets (NSs) on a three-dimension (3D) nickel foam (NF) scaffold via anion-exchange transformation is achieved by employing low temperature scalable hydrothermal process. Being an active catalyst material for glucose detection, the CoTe 2 NSs/NF electrode demonstrates an ultra-prompt response time of 0.1 s, boosting sensitivity of 168000 μA mM −1 cm −2 , low limit of detection of 0.59 μM along with excellent anti-interference ability and favorable stability. Besides, the effective electrochemical performance of sensing electrode is recognized with respect to the glucose detection in real human blood serum. Overall, this material guarantees free-standing 3D architecture, interconnected porous NSs morphology, large specific surface area, high conductivity, and appealing electro-catalytic activity. Therefore, the porous CoTe 2 NSs/NF binder-free electrode has a great application prospect as a promising biomimetic catalyst material for highly sensitive and efficient non-enzymatic glucose sensor.
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Analytical Methods
·
2020
·Vol. 12
·期 37
·4551-4555
·
IF 2.596
Haijian Liu,Miao Wang,Zhenxiang Li,Chengjie Xin,Guofu Huang
Due to the inner filter effect (IFE) between Brilliant Blue (BB) and gold nanoclusters (AuNCs), a simple and rapid approach for BB detection was developed. Since the absorption spectrum of BB has a good overlap with the emission spectrum of the AuNCs, the fluorescence of the AuNC solution was quenched after adding BB. Under optimal conditions, a good linear relationship for detection of BB was obtained from 0.05 to 7.5 μM, and the detection limit was 0.0167 μM. More importantly, the assay was successfully applied to assess BB in food samples such as hard candy, chocolate and dried blueberries, showing its potential in food quality control in the future.
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