Biosensors-Basel
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2025
·Vol. 15
·期 5
·313
·
IF 5.6
Yinjun Li,Hua Ding,Ziyu Wang,Zewei Luo,Xitian Peng
Lateral flow immunoassay (LFIA) is a promising tool for rapid detection in the field of agricultural product analysis due to its advantages of cost-effectiveness and operational simplicity. In this work, Eu metal–organic frameworks (MOFs) were introduced to LFIA as a rapid detection method characterized by high stability and low interference. Key research objectives included strong fluorescence, ease of labeling, and the utilization of fluorescent probes. Eu-MOFs were synthesized in one step via the hydrothermal method, exhibiting a fluorescence lifetime of 163 μs and spherical particles with diameters ranging from 250 to 400 nm. These conditions fulfill the characteristics and requirements of LFIA. Eu-MOFs exploit the porous nature of MOFs to mitigate the drawbacks associated with complex crosslinking agents. This enables antibody proteins to be cross-linked merely upon contact, thereby simplifying the detection process. A time-resolved LFIA method was developed utilizing Eu-MOFs for the detection of aflatoxin B1 (AFB1) in corn, achieving a limit of detection (LOD, IC10) of 0.149 ng/mL. The accuracy and reliability of the Eu-MOFs-LFIA method were validated through comparisons with spiked concentrations during spiking and blind sample analyses, with verification conducted using ultra-high-performance liquid chromatography mass spectrometry (UPLC-MS). Furthermore, testing of real samples demonstrated that the Eu-MOFs-LFIA method can effectively facilitate rapid detection of AFB1 in corn.
研究领域:
食品科学
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分析化学
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生物技术
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DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2022
·Vol. 106
·期 3
·1778-1788
·
IF 4.186
Xiao Ma,Zhifeng Huang,Hailong Yuan,Yujuan Zhou,Meijuan Li,Fei Chen,Qiang Shen
Rare-earth-doped transparent glass shows great potential in white light-emitting diodes (wLEDs) application due to its excellent optical and luminous properties. Currently reported commercial wLEDs have a drawback in red emission missing, which leads to a relatively low color rendering index (CRI) and a relatively high correlated color temperature (CCT). In this work, Ce@Eu Sr–Si–O glass is fabricated using a high-temperature quenching method. The white light is available when the ratio of Ce 3+ /Eu 3+ equals 1, and the emitting color can be adjusted from blue to red by controlling the ratio of Ce 3+ /Eu 3+ . To further optimize the white light, Eu 3+ ions can be reduced to Eu 2+ according to the reaction of 6Eu 3+ + 2N 3− → 6Eu 2+ + N 2 ↑ by introducing Si 3 N 4 . As a result, the standard white light emission can be achieved in the Ce@Eu silicate glass contributed by the blue light from Ce 3+ , red light from Eu 3+ , and yellow–green light from Eu 2+ (two elements, three emission). This glass shows excellent luminous properties, such as a color coordinate is (0.3651, 0.3269) in CIE 1931 color coordinate diagram, a CRI is over 70, a high quantum yield of 36.02%, and a CCT of 4117 K.
研究领域:
材料科学
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光学
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DOI
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Kuiyu Yi,Lei Zhang
An ingenious nanoscale fluorescent sensor derived from Eu 3+ -postfunctionalized MIL-53 (Al) (Eu 3+ @MIL-53 [Al]) was fabricated though a simple and effective approach. Malachite green (MG) effectively turned off the luminescence of Eu 3+ @MIL-53 (Al) via fluorescence resonance energy transfer (FRET), thus enabling MG sensing. The developed probe exhibited instantaneous reusability after being cleaned with deionized water. The fluorescence intensity, quenching efficiency, and crystal structure of the recoverable sensor after five recycling processes were unchanged compared with those of the original sample. Moreover, the potential mechanism of MG detection was revealed in detail. This work represents the first attempt to determine MG in aquaculture water and products by using metal–organic frameworks (MOFs). The Eu 3+ @MIL-53 (Al) probe proved to be a remarkable fluorescence probe for MG with high selectivity, sensitivity, and excellent regeneration capability. It provides a promising functional platform for the recognition of illegal MG addition to aquaculture water and products.
研究领域:
材料科学
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环境科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Zhihua Li,Lin Chen,Jiaxi Deng,Jing Zhang,Cailin Qiao,Mei Yang,Guoren Xu,Xiaogang Luo,Danqun Huo,Changjun Hou
Water contamination caused by heavy metals represents an urgent global issue. Cu 2+ , a potential trace heavy metal pollutant, can accumulate in the human body through the food chain, leading to excessive levels that give rise to diverse health complications. Hence, in this investigation, a novel and efficacious fluorescent probe named Eu-BTB was developed for the detection of Cu 2+ , employing 1,3,5-triphenyl(4-carboxyphenyl) (H 3 BTB) as the ligand and Eu 3+ as the metallic framework. The probe demonstrates exceptional fluorescence characteristics. The interaction between the probe ligand BTB and Eu 3+ triggers an antenna effect, heightening the emission efficiency of Eu 3+ while preserving its intrinsic emission. The introduction of Cu 2+ competes with BTB for binding, thus quelling the antenna effect and inducing a fluorescence alteration. Within the concentration range of 0.05–10 μM, the fluorescence intensity-to-Cu 2+ concentration ratio exhibits a robust linear correlation, with a remarkably low detection limit of 10 nM and a rapid response time of 3 min. The fluorescent probe has been effectively deployed for the detection of copper ions in water across diverse environmental conditions, with the obtained outcomes being validated via the conventional approach of inductively coupled plasma mass spectrometry (ICP-MS). The Eu-BTB probe showcases the advantages of simplicity, swiftness, and broad applicability, thus affirming its potential for the prompt and accurate detection of Cu 2+ in diverse environmental water samples.
研究领域:
环境科学
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分析化学
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材料科学
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Shuai Sha,Fan Qiu,Jiaxi Liu,Yin Zhang,Hao Xu,Xianhui Mei,Xiangyuan Wang,Jie Zhang
This paper introduces a novel composite bone cement (Eu:HAp/V-C 3 S), which is composed of carbonated tricalcium silicate (V-C 3 S) and europium-doped hydroxyapatite (Eu:HAp), and Eu:HAp was generated by hydrothermal synthesis . The physical and chemical properties, mineralization in vitro, biocompatibility and bacteriostasis of the composite bone cement were evaluated. The results show that the Eu:HAp/V-C 3 S composite bone cement has good setting properties and a relatively low pH value. The composite bone cement with 0.1 wt% Eu has a higher compressive strength than pure V-C 3 S (141.06% higher than pure V-C 3 S), which can greatly improve the mechanical properties of the materials. The in vitro immersion test shows that composite bone cement has good mineralization ability. The cell test proves that it has good cell proliferation ability and low cytotoxicity. In addition, the bacteriostatic experiment also verifies that composite bone cement has bacteriostatic effect to some degree. These results indicate that Eu:HAp/V-C 3 S composite bone cement is a promising biomedical material .
研究领域:
材料科学
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生物医学工程
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Jie Xiong,Yunfang Xiao,Jiaman Liang,Jian Sun,Lixia Gao,Qiuju Zhou,Dan Hong,Kejun Tan
As we all know, excessive hypochlorite will be transformed into highly toxic substances, while insufficient hypochlorite can not completely kill bacteria and viruses in water. Therefore, it is desirable to develop a new analytical method to detect ClO - in environmental water. Here, a novel and simple fluorescence sensor was constructed for monitoring ClO - by an effective strategy. An Acriflavine@lanthanide metal-organic framework (Acr@Eu(BTEC)) was designed by covalently integrating amino-rich dye (Acr) and carboxyl-rich Eu(BTEC) via post-synthesis method. The created fluorescence sensor has two emission centers originating from Acr and Eu(BTEC), respectively. In the presence of ClO - , the strong green fluorescence derived from Acr was significantly quenched, while the invariant red emission from Eu 3+ acted as the reference signal. Thus, Acr@Eu(BTEC) with two emissions was developed as a ratiometric fluorescence sensor for highly sensitive and selective detection of ClO - . The limit of detection (LOD) was as low as 10.75 nM. Moreover, visual detection of ClO - by the naked eyes is feasible with obvious fluorescent color changes from green to orange and then red. This method shows excellent performance in practical application, which suggests that it has great potential in water quality monitoring.
研究领域:
环境科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Zifei Wu,Hao Ding,Kailai Xu,Chenghui Li,Xiandeng Hou
Background due to the toxicity and widespread distribution of inorganic mercury ions (Hg 2+ ), it is a crucial task for researchers to develop simple methods for field analysis of water samples for trace Hg 2+ . Result a colorimetric and ratiometric fluorescent dual-mode assay based on bifunctional UiO–(COOH) 2 –NH 2 /Eu and gold nanocomplexes (AuNPs@UiO–(COOH) 2 –NH 2 /Eu) was constructed for the sensitive, selective and potentially on-site determination of Hg 2+ . The incorporation of Hg 2+ resulted in the formation of gold amalgam, which enhanced peroxidase-like activity of AuNPs@UiO–(COOH) 2 –NH 2 /Eu, accelerating the oxidization of zymolyte 3,3′,5,5′-tetramethylbenzidine (TMB). Concurrently, the color of the reaction solution turned blue, and the RGB (red, green, and blue) of the solution color changed accordingly. The fluorescence at 618 nm was almost unchanged with the increase of Hg 2+ concentration, whereas the fluorescence at 460 nm was obviously quenched due to the inner filter effect (IFE). Under UV irradiation, the fluorescence emission of the sensing system changed from blue to red, enabling easy visual detection. The probe showed great linearity over a wide range of 20–1200 nM (colorimetric) and 50–4000 nM (fluorescent), with limits of detection (LODs) of 8 nM and 3 nM, respectively. Significance the proposed method was successfully applied to the determination of trace Hg 2+ in tap water and groundwater, while the use of a smartphone enables its simplicity and portability. The results show that the colorimetric and ratiometric fluorescent dual-mode method based on AuNPs@UiO–(COOH) 2 –NH 2 /Eu can achieve rapid visual determination of Hg 2+ potentially useful for on-site analysis.
研究领域:
分析化学
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环境科学
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纳米技术
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Yunchuan Dai,Pengyu Hu,Tingting Chu,Meihong Niu,Haiqiang Shi,Haiming Li,Zhiwei Wang,Yanzhu Guo
As a novel fluorescent carbon nanomaterial, carbon dots are restricted by their poor fluorescence in the solid state, although they exhibit favorable photoluminescence in solution. N-doped carbon dots (N-CDs) and solid-state fluorescence films were prepared using green and renewable cellulose-derived materials, respectively. The hydrogen bonding network of carboxymethyl cellulose (CMC) inhibits the self-aggregation behavior of N-CDs, which leads to solid-state fluorescence. The N-CDs was initially obtained with CMC as the carbon source, which showed excellent blue fluorescence. Subsequently, the white-emitting films (N-CDs@Eu-MOF/CMC) were successfully constructed by combining the blue fluorescent N-CDs with the red fluorescence of the europium metal-organic framework. The prepared films showed stable luminescence within 30 days and in the heat environment at 120 °C for 3 h. After covering the N-CDs@Eu-MOF/CMC films on the UV-LED chip with ultraviolet emissive at 365 nm, the white light-emitting diodes were obtained, which exhibited excellent color characteristics with the color coordinates, a correlated color temperature, and a color rendering index of (0.31, 0.32), 6580 K, and 92, respectively. The strategy proposed in this work will provide ideas for generating optical luminescent films from biomass and provide guidance for solid-state fluorescence biomass materials.
研究领域:
材料科学
·
光学
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Yan Wu,Yue Zhou,Hongchen Long,Xiangyu Chen,Yuanyuan Jiang,Lei Zhang,Tao Le
The study investigates a bimetallic organic framework (Zn/Eu-MOF) based fluorescent probe for visual detection of ofloxacin (OFL) in pork, beef and fish. The developed sensing probe recognizes OFL through internal filtration and cation-π interaction between OFL and Zn/Eu-MOF, resulting in a distinct color change from orange-red to light green. The content of OFL can be determined through RGB analysis by a mobile-phone. The developed sensing probe offers several advantages such as broad linear range (0.1 ∼ 80 μM), rapid response time (30 s), low detection line (0.44 μM). The effectiveness of the sensing probe can last for five rounds with good recovery. Moreover, the application of the sensing probe on pork, beef and fish samples are reliable, with recoveries ranging from 93.4 to 112.1%, and the relative standard deviations (RSD) within 1.17% to 2.06%. These results suggest that the developed sensing probe could have significant potential for practical on-site test in food.
研究领域:
食品科学
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分析化学
·
生物传感
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产品关联
DOI
PubMed
高影响因子
TALANTA
·
2025
·
IF 6.1
Shuyun Zhu,Kunming Sun,Shuyi Liu,Qian Wang,Jiatong Fan,Xian-En Zhao,Guobao Xu
Flavonoid glycosides are formed by dehydration condensation of aglycones and sugar molecules. Therefore, discrimination of flavonoid glycosides from their corresponding aglycones is a challenging task because they contain the same aglycone part in their molecular structures. Herein, boric acid-functional Eu(III)-organic framework (BA-Eu-MOF) was applied to discriminate flavonoid glycosides including baicalin (Bai), wogonoside (Wog), rutin (Rut), puerarin (Pue), quercitrin (Que) and astragalin (Ast) from their corresponding aglycones for the first time. Besides as organic ligand to sensitize the luminescence of Eu 3+ through “antenna” effect, 5-boronobenzene-1,3 dicarboxylic acid provided recognition site for flavonoid glycosides. Infrared, fluorescence, UV–vis, and mass spectra were used to investigate the recognition reaction between BA-Eu-MOF and flavonoid glycosides. The data indicated that the cis -diols of flavonoid glycosides from sugars covalently bonded to boric acid group to form cyclic boronic esters, which quenched the fluorescence of BA-Eu-MOF at 620 nm through decreasing the intersystem efficiency, inner filter effect and photoelectron transfer. In contrast, aglycones could not alter the fluorescence of BA-Eu-MOF because of no covalent bond between them. This probe exhibited high sensitivity towards flavonoid glycosides with the low detection limits of 3.3 nM, 3.5 nM, 33 nM, 56 nM, 5.1 nM and 5.5 nM for Bai, Que, Wog, Ast, Pue and Rut, respectively. The unique recognition ability of boric acid group enables selective and sensitive detection of flavonoid glycosides without the interference of their corresponding aglycones.
研究领域:
化学
·
药理学
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产品关联
DOI
PubMed
高影响因子
Catalysis Science & Technology
·
2023
·Vol. 13
·期 10
·3060-3068
·
IF 5
Guanghua Liang,Jianyi Chen,Tao Dou,Zhijie Wu,Xiaofeng Li,Yuanshuai Liu
EU-1 zeolite is employed as an active component of a catalyst for isomerization or hydroisomerization of C8 aromatics (i.e., xylenes, ethylbenzene) in petrochemical processes to increase the para-xylene yield. However, conventional manufacturing of EU-1-based catalysts involves the production of mother liquors for zeolite synthesis which usually contain plentiful unreacted raw materials, or the negative impact of incorporated binders in mass transfer during reactions over shaped catalysts. Herein, we developed a novel route to prepare the monolithic EU-1 zeolite, and used it as an active component of a catalyst for hydroisomerization of ethylbenzene with meta-xylene. Recrystallization of the shaped zeolite precursors composed of incompletely crystallized zeolites with amorphous silica and alumina powders as binders in recycled mother liquor led to formation of the monolithic EU-1 zeolite. Transformation of binder species to a full-zeolitic phase was corroborated comprehensively by characterization methods. Compared with the conventionally fabricated counterpart, the monolithic EU-1 zeolite possessed similar mechanical strength, high crystallinity, and high acidity and, in particular, enhanced mesoporosity, which led to improved catalytic performances in hydroisomerization reactions. Our developed synthetic strategy provides an effective way to produce the monolithic EU-1 zeolite, but is also a reference for the sustainable production of other types of zeolitic materials for energy-related applications.
研究领域:
化学工程
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催化材料科学
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产品关联
DOI
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Huifeng Xu,Weihua Huang,Rui Pan,Ronglin Chen,Lili Wang,Yun Yu,Xihai Li,Xi Zhu
A stable dual-emission fluorescent system, R6G/Eu-MOF, was obtained by simple mixing Eu-MOF with fluorescent rhodamine 6G (R6G). This system not only achieved robust dual luminescence performance at 430 nm (Eu-MOF) and 555 nm (R6G) under single-wavelength excitation, but also endowed it significantly improved fluorescence stability. Orientin (OT), a bioactive traditional Chinese medicine (TCM) component, was found to efficiently quench the dual fluorescent emissions via the synergistic effect of dynamic quenching effect, photo-induced electron transfer and molecular interactions. Therefore, a rapid fluorescent assay for OT was developed based on the variations in fluorescence signals at 430 nm and 555 nm, as well as the alterations in the ratio between these two signals. This method can achieve highly sensitive determination of OT in the linear range of 1.1-220 µM, with a LOD of 0.26 µM at 430 nm and 0.16 µM at 555 nm (3σ/N). The R6G/Eu-MOF hybrid exhibits significantly lower detection limits and a broader linear range OT than either R6G or Eu-MOF alone. This work presents a simple strategy to improve the water stability of Eu-MOF, and also provides a rapid analysis of small molecule drug using a fluorescence approach based on dual-emission MOF hybrid system.
研究领域:
分析化学
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药物分析
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材料科学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）