FOOD CHEMISTRY
·
2019
·
IF 5.399
Danyu Zhang,Shiwei Yang,Qingfang Ma,Jiannan Sun,Heyong Cheng,Yuanchao Wang,Jinhua Liu
This work establishes a hyphenated methodology coupling HPLC with ICP-MS for simultaneous speciation analysis of arsenic, mercury and lead for the first time. Four arsenicals (As(III), DMA, MMA and As(V)), four mercurials (Hg(II), MeHg, EtHg and PhHg) and three lead compounds (Pb(II), TML and TEL) were simultaneously analyzed within only 8 min with acceptable resolution (2.0–8.2 for As, 1.6–6.1 for Hg and 2.7–4.0 for Pb). The detection limits were 0.036–0.20 for As-species, 0.023–0.041 for Hg-species, and 0.0076–0.14 μg L −1 for Pb-species. The developed method was applied for the measurement of five lotus seed samples, indicating the presence of DMA (19.6–28.2 μg kg −1 ), TML (1.4–2.9 μg kg −1 ), MeHg (1.2–4.8 μg kg −1 ) and EtHg (0.8–2.2 μg kg −1 ). This method provides a promising tool for studying the toxic, metabolic and bioavailable behaviors of arsenic, mercury and lead.
研究领域:
分析化学
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环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2024
·
IF 5.6
Yukun Huang,Guangyu Chen,Biao Fu,Yingfu Si,Peng Li,Yijun Cao,Lingkun Rong,Chunjie Zhao
This study developed a rapid and efficient graphite furnace digestion combined with inductively coupled plasma emission spectrometry (ICP-OES) method, enabling precise quantification of germanium (Ge) in coal and various coal-derived metallurgical byproducts across a broad concentration level (∼ppm-n%). The graphite furnace digestion conditions were examined intensively as a function of the acid amounts of HNO 3 and HF (5–10 mL), temperature (80–180 °C), time (1–5 h), and acid drive methods (H 3 BO 3 neutralization versus heating). Coal references including SARM 19, SARM 20, NIST SRM 1632e, and fly ash standard NIST SRM 2689 were tested. The optimum recovery of germanium was obtained when the HNO 3 dosage, HF dosage, solid sample mass, temperature, and duration time were 10 mL, 5 mL, 0.1 g, 80 °C and 1 h. Agreement of 95.15–96.54 % between the measured and certified value was obtained under the optimum conditions. The spiked recovery was 103.23–103.54 %, indicating the matrix-analytes interactions were negligible. Boric acid neutralization reduced the recovery rates to 47.2–49.3 % and was not be appropriate for driving HF. The optimal spectral line for determining Ge is at a wavelength of 265.117 nm, at which the limit of detect and the limit of quantification were 0.46 μg L −1 and 1.53 μg L −1 , respectively. The applicability of the method was validated by quantifying Ge in Ge-rich lignite, fly ashes (FA), and chlorinated distillation residue (CR) samples. The concentration of Ge in coals was 44.75–225.41 μg g −1 , the content in FA was 0.68%–2.3 %, and the content in CR was 0.18 %, with the uncertainty of the method obtained being less than 0.5 %. X-ray fluorescence spectrometer (XRF) was used to verify the results. The difference between XRF data and ICP-OES data was less than 5 %, confirming the accuracy and reproductivity of the analytical method.
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2024
·Vol. 333
·期 3
·1357-1365
·
IF 1.5
Mei Lingzi,Shao Hui,Cui Lingzhi,Yang Jinmin,Zhang Lei
A novel method for rapid radioanalytical measurement of uranium and plutonium in 100ml emergency urine samples was developed, through optimized selection of the separation and purification process and a combined measurement with ICP-TOF-MS and alpha spectrometry. The typical analytical time is within 6 h, the recovery rates are more than 80%, and the minimum detection activity concentrations are 3.4 × 10 −4 Bq/L for 238 U and 2.5 × 10 −3 Bq/L for 239 Pu respectively. The spiked test shows that this method can be used for quantitative evaluation of the activity concentration of 238 U and 239 Pu in urine samples accurately.
研究领域:
放射化学
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环境科学
·
医学检测
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2025
·
IF 2.6
Yong-Hai Yuan,Feng Yang,Qiu Zhang,Qinghong Xu,Meilan Wen
This study focuses on comparing the performance of pneumatic nebulization (PN), hydride generation (HG), and photochemical vapor generation (PVG) sampling modes coupled with inductively coupled plasma mass spectrometry (ICP-MS) for the determination of Se and Te in geological samples. ICP-MS operating parameters for each sampling mode, such as RF power, flow rate of collision gas, and sampling depth, were optimized. The introduction efficiency of Se and Te in PN mode was about 4.71% and 4.58% respectively, with the best reproducibility. HG mode had the highest introduction efficiency (57.01% for Se and 53.02% for Te), but the poorest reproducibility. PVG mode showed a good balance between efficiency and reproducibility, with introduction efficiencies of 45.38% for Se and 38.84% for Te, and lower limits of detection (LODs) of 0.001 μg·L-¹ for both Se and Te. Analysis of 14 geological certified reference materials (CRMs) indicated that for samples with Se > 0.1 μg·g-¹ and Te > 0.05 μg·g-¹, both PN and PVG sampling modes can obtain satisfactory results, and PN mode is more convenient. For samples with Se ≤ 0.1 μg·g-¹ and Te ≤ 0.05 μg·g-¹, HG or PVG sampling modes are recommended after enrichment pretreatment. This research provides a more precise and reliable method selection basis for analyzing Se and Te in geological samples at different concentration levels.
研究领域:
分析化学
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地球化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Sciences
·
2020
·
IF 4.302
Zhao-Feng Yuan,Williamson Gustave,Raju Sekar,Jonathan Bridge,Jia-Yue Wang,Wei-Jia Feng,Bin Guo,Zheng Chen
The redox-sensitive elements, such as iron, manganese, sulfur, phosphorus, and arsenic, shift their speciation every millimeter (mm) across the soil-water interface in the flooded soil environments. Monitoring of element speciation at this high-resolution (HR) within the SWI is still difficult. The key challenge lies in obtaining sufficient porewater samples at specific locations along the soil gradient for downstream analysis. Here with an optimized inductively coupled plasma mass spectrometry (ICP-MS) method and a HR porewater sampler, we demonstrate mm-scale element profiles mapping across the SWI in paddy soils. High-concentrations of iron and manganese (> 10 mg/L) were measured by ICP-MS in an extended dynamic range mode to avoid signal overflow. The iron profile along the SWI generated by the ICP-MS method showed no significant difference ( p < 0.05) compared to that measured independently using a colorimetric method. Furthermore, four arsenic (arsenite, arsenate, monomethylarsonic and dimethylarsinic acid), two phosphorus (phosphite and phosphate) and two sulfur (sulfide and sulfate) species were separated in 10 min by ion chromatography -ICP-MS with the NH 4 HCO 3 mobile phase. We verified the technique using paddy soils collected from the field, and present the mm-scale profiles of iron, manganese, and arsenic, phosphorus, sulfur species (relative standard deviation < 8%). The technique developed in this study will significantly promote the measurement throughput in limited samples (e.g. 100 μL) collected by HR samplers, which would greatly facilitate redox-sensitive elements biogeochemical cycling in saturated soils.
研究领域:
土壤学
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环境科学
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分析化学
✓ 已验证
DOI
PubMed
高影响因子
Analytical Methods
·
2012
·Vol. 4
·期 10
·3471-3477
·
IF 1.547
Xu Han,Lianghui Cao,Heyong Cheng,Jinhua Liu,Zigang Xu
Ion-pair reversed phase high performance liquid chromatography coupled to inductively coupled plasma mass spectrometry (RP-HPLC-ICP-MS) has been used to determine two inorganic iodine species (I− and IO3−) and two organic iodinated amino acids (MIT and DIT) in seaweed and seawater samples within 5 min. The mobile phase used for a reversed phase C18 column was as follows: 2.0 mM tetraethylammonium hydroxide, 10 mM L-phenylalanine and 1% methanol (pH 8.9). Values of 1.5 mL min−1 for the flow rate of the mobile phase and 25 °C for the column temperature were selected for rapid separation of iodine species. The detection limits for IO3−, I−, MIT and DIT were 0.061, 0.052, 0.079 and 0.24 μg L−1, each, and the repeatabilities of peak height and peak area (20 μg L−1 for iodide and iodate, 40 μg L−1 for MIT, 100 μg L−1 for DIT) were all lower than 4%. Under the optimized conditions, the proposed method was successfully applied for the speciation analysis of iodine in seaweed and seawater samples. Recoveries of IO3−, I−, MIT and DIT in seaweed and seawater samples were between 90 and 110%. All results prove its advantages including high sensitivity, environmentally friendly, low time consumption, which are beneficial for routine analysis of iodine speciation in environmental and food fields.
研究领域:
分析化学
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环境科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
·
2014
·Vol. 30
·期 12
·3245-3250
·
IF 1.353
Guo Xuena,Liu Wei,Bai Xuejing,He Xiuping,Zhang Borun
High-performance liquid chromatography was used to separate Cr(III) and Cr(VI) in samples with detection by inductively coupled plasma mass spectrometry(ICP-MS). The separation was achieved on a weak anion exchange column. The mobile phase was pH 7.0 ammonium nitrate solution. The redox reaction between Cr(III) and Cr(VI) was avoided during separation and determination. This separation method could be used to separate the samples with large concentration differences between Cr(III) and Cr(VI). The alkaline digestion was used to extract chromium in solid sample, which had no effect on the retention time and the peak area of the Cr(VI). However, the conversion of Cr(VI) from Cr(III) was observed during alkaline digestion, which displayed positive relation with the ratio of Cr(III) and Cr(VI) in samples. Both Cr(III) and Cr(VI) contents of chromium yeasts cultured in media with different chromium additions were determined. The spike recoveries of Cr(VI) for chromium yeasts were in the range of 95–108 %.
研究领域:
分析化学
·
环境科学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Kesheng Hu,Linlin Zhang,Haolin Zhou,Yuankun Liu,Shuying Liu,Beijia Chang,Xiaoqing Gao,Junqiang Yang,Keliang Shi,Xiaolin Hou
Selenium is a crucial trace element for antioxidant defense and immune function, with its health benefits varying significantly based on its chemical form. Tea, a widely consumed beverage, holds potential as a significant dietary source of selenium. However, the variations in selenium content and speciation in tea, influenced by cultivation and processing methods, have not been thoroughly studied, nor has the effect of brewing conditions on selenium release. This work addresses these gaps by developing a method utilizing inductively coupled plasma mass spectrometry to accurately quantify total selenium content and its speciation in tea samples. We optimized microwave digestion conditions to establish a rapid and efficient protocol for measuring total selenium and evaluated different brewing conditions to determine their impact on selenium extraction, identifying optimal parameters to maximize selenium intake from tea infusions. Additionally, AG1 × 4 ion exchange resin was employed to separate inorganic from organic selenium, and a method to extract and purify selenium bound to key tea components such as polyphenols, polysaccharides, and proteins was developed, with the extraction parameters optimized. Our findings provide a thorough understanding of selenium speciation in tea and highlight the importance of brewing conditions in enhancing selenium bioavailability, offering valuable insights for the development of selenium-enriched teas and advancing healthier dietary practices.
研究领域:
食品科学
·
分析化学
·
营养学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Manlu Wang,Juan He,Jin Luo,Jing Hu,Xiandeng Hou
The determination of inorganic arsenic species in real samples can be particularly challenging due to their trace levels and the interferences arising from sample matrix. Normally, the speciation analysis necessitates chromatographic separation. Herein, we report a novel method for the ultrasensitive detection and non-chromatographic speciation of inorganic arsenic by inductively coupled plasma mass spectrometry (ICP-MS), utilizing CdS/MIL-100(Fe) composites as an adsorbent and photocatalyst. The synthesized CdS/MIL-100(Fe) could completely adsorb As(V) and As(III) within 5 and 105 min, respectively. Following filtration and re-suspension in formic acid, the adsorbed As(III)/As(V) were reduced to arsine (AsH 3 ) under UV irradiation and swept to ICP-MS for detection. The limits of detection were found to be 1.7 ng L −1 (without preconcentration) and 0.11 ng L −1 (after 20-fold preconcentration). The method was successfully applied to the determination of trace inorganic arsenic in various food and water samples.
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
DOI
PubMed
高影响因子
TALANTA
·
2025
·
IF 6.1
Haowen Hu,Zhengxian Lv,Yixin Guo,Li Yi,Limin Yang,Xiaowen Yan,Qiuquan Wang
Inductively coupled plasma mass spectrometry (ICP-MS) has demonstrated high sensitivity, accuracy, and multi-element detection capacity for biomolecule analysis. However, traditional ICP-MS-used antibody-elemental tags (AETs) are typically constructed through random antibody modification, resulting in structural heterogeneity that compromises binding affinity, specificity, and analytical performance. To overcome this limitation, we developed a traceless, site-specific conjugation strategy that enables precise attachment of a single-stranded DNA (ssDNA) to the K248 residue of IgG antibodies. The “traceless” feature ensures that no residual peptide remains on the antibody after labeling, thereby preserving its native structure and binding activity. The ssDNA serves as a bridge for hybridization with europium (Eu)-loaded MS2 capsid nanoparticles, which act as signal amplifiers by delivering a large payload of metal atoms. Through the integration of precise antibody modification and high-capacity MS2 elemental carriers, the resulting site-specific AETs (ssAETs) exhibit exceptional structural uniformity, stability, and sensitivity. Using human epidermal growth factor receptor 2 (HER2) as a model, the AETs synthesized through our strategy demonstrated exceptional specificity and quantitative performance, achieving 1.8-fold stronger single-cell signals and labeling 1.5 times more HER2-positive cells compared with randomly conjugated antibodies. This traceless, site-specific ssAET platform offers a versatile and precise approach for highly sensitive and quantitative single-cell bioanalysis using ICP-MS.
研究领域:
分析化学
·
免疫学
·
分子生物学
·
肿瘤学
·
转化医学
·
生物标记物检测
·
单细胞分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2025
·
IF 0
Qin Chuan,Jiao Yanni,Yang Luping,Wang Lin,Kong Zhengqiao,Jiang Dafeng,Zhang Jiacheng,Zhang Tianliang,Gao Xibao
Arsenic species were quantified to further explore the biotransformation of arsenic and better explain the potential health risks. In this research, the levels of six arsenic species (AsB, AsC, MMA, DMA, As 3+ , and As 5+ ) were determined in 160 squid samples by HPLC-ICP-MS. AsB was the most predominant speciation in squid tissues. The arsenic species, including AsB, AsC, and MMA, were found in all samples, followed by DMA (49.38%), As 3+ (21.25%), and As 5+ (2.5%). Results indicated squid samples from offshore had higher levels of AsB, AsC, MMA, and DMA. Pearson’s correlation analysis found correlations between As-MMA, DMA-As 5+ , and AsB-MMA, which showed a clear methylation pathway. The levels of inorganic arsenic were below the standard, and no potential health risks were identified. Therefore, the application of total arsenic in our previous study to assess health risks may be biased. In future, there is a need to optimize food safety monitoring of arsenic and comprehensively grasp the basic status and change law of marine ecological environment.
研究领域:
食品安全
·
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
Pigment & Resin Technology
·
2023
·Vol. 53
·期 5
·638-649
·
IF 1.4
Shan Peng,Ranran Yang,Binglong Lei,Yun Gao,Renhua Chen,Xiaohong Xia,Kevin P. Homewood
PurposeThis paper aims to systematically demonstrate a methodology to determine the relative and absolute encapsulation efficiencies (αReandαAb) for thermally- and chemically-robust inorganic pigments, typically like ZrSiO4-based pigments, thereby enhancing their coloring performance.Design/methodology/approachThe authors designed a route, surplus alkali-decomposition and subsequently strong-acid dissolution (SAD2) to completely decompose three classic zircon pigments (Pr–ZrSiO4, Fe2O3@ZrSiO4and CdS@ZrSiO4) into clear solutions and preferably used inductively coupled plasma-optical emission spectrometry (ICP-OES) to determine the concentrations of host elements and chromophores, thereby deriving the numeric data and interrelation ofαReandαAb.FindingsZircon pigments can be thoroughly decomposed into some dissoluble zirconate–silicate resultants by SAD2 at a ratio of the fluxing agent to pigment over 6. ICP-OES is proved more suitable than some other quantification techniques in deriving the compositional concentrations, thereby the values ofαReandαAb, and their transformation coefficientKRA, which maintains stably within 0.8–0.9 in Fe2O3@ZrSiO4and CdS@ZrSiO4and is slightly reduced to 0.67–0.85 in Pr–ZrSiO4.Practical implicationsThe SAD2 method and encapsulation efficiencies are well applicable for both zircon pigments and the other pigmental or non-pigmental inhomogeneous systems in characterizing their accurate composition.Originality/valueThe authors herein first proposed strict definitions for the relative and absolute encapsulation efficiencies for inorganic pigments, developed a relatively stringent methodology to determine their accurate values and interrelation.
研究领域:
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）