MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 2
·1-11
·
IF 6.232
Wang Jiajia,Wang Jinlong,Zhou Pei,Tao Han,Wang Xueli,Wu Yuangen
A colorimetric assay for the determination of heavy metal ions is presented that is based on the regulation of the oxidase-mimicking activity of Mn 3 O 4 nanoparticles (NPs) by oligonucleotides. The chromogenic agent tetramethylbenzidine (TMB) is oxidized by the catalytic action of Mn 3 O 4 NPs to generate products that have a yellow color in acidic solution, with a peak at 450 nm. It is found that random oligonucleotides are absorbed on the regular surface of the Mn 3 O 4 NPs and temporarily inhibit the oxidation of TMB. This leads to a decrease in absorbance and a light-green coloration of the solution. The results show that the purine bases in oligonucleotides play a key role in their regulation of the activity of the NPs. The regulatory effect is assumed to be of the noncompetitive type. In the presence of heavy metal ions like Hg(II) or Cd(II), the inhibition is canceled due to the binding of heavy metal ions to thymine bases, and the color of the solution changes from light green to yellow. The increase in absorbance at 450 nm is related to the amount of heavy metal ions present. The method allows Hg(II) and Cd(II) to be determined visually in concentrations as low as 20 μg·L −1 . The detection limit of the colorimetric assay is 3.8 and 2.4 μg·L −1 of Hg(II) and Cd(II), respectively. The assay displays good selectivity over other heavy metal ions. The method was successfully validated by analyzing several water samples.
Schematic representation of the colorimetric assay for Hg(II) and Cd(II) based on the intrinsic oxidase-mimicking activity of Mn 3 O 4 nanoparticles that is regulated by oligonucleotides.
研究领域:
分析化学
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纳米技术
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环境科学
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生物化学
✓ 已验证
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Binghong Chen,Jing Wang,Renjie Li,Hongjun Lin,Bisheng Li,Liguo Shen,Yanchao Xu,Meijia Zhang
Integration of sulfate radicals-based advanced oxidation processes (SR-AOPs) with separation membranes has enthralled considerable attentions because it can remove persistent toxic micropollutants in a low-energy and cost-effective manner. However, fabrication of such an integrated membrane simultaneously with excellent self-cleaning property, catalytic capability and long-term durability remains a challenge. Herein, for the first time, CoFe 2 O 4 (CFO) and Mn 3 O 4 (MO) nanoparticles were anchored on ultrathin graphitic carbon nitride (UCN) nanosheets via a solvothermal method to prepare heterogeneous Fenton-like catalysts (MO/CFOUCN). Systematic characterizations demonstrated the successful preparation of powder catalysts with favorable degradation ability. Notably, the optimal composite catalyst possessed satisfactory degradation (94.5 %) and kinetic rate (0.1367 min −1 ) for norfloxacin (NOR) within 30 min. Thereafter, an integrated MO/CFO/UCN@P membrane was fabricated by vacuum-assisted filtration of the catalyst on a supporting membrane surface. It was interestingly found that, benefiting from the synergistic effect of in-situ oxidation and membrane filtration, activating peroxymonosulfate (PMS) endowed the membrane with high removal rates (over 91.8 % for tetracycline, bisphenol A, humic acid (HA)) and high permeation flux (332.7 L·m −2 ·h −1 ) driven solely by gravity. Significantly, the membrane achieved a flux recovery rate of 91.9 % with the assistance of PMS after filtering HA solution. Furthermore, quenching experiments and electron paramagnetic resonance (EPR) tests confirmed that both radical and nonradical pathways contributed to the mineralization of NOR. Based on the detection of intermediates in the degradation process, potential NOR degradation pathways were proposed. Overall, this study provided new ideas about integrating Fenton-like catalysts with membrane technology for removal of persistent organic pollutants.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2021
·Vol. 32
·期 40
·405403
·
IF 3.874
L Chen,Y F Yuan,P F Du,S M Yin,M Zhu,S Y Guo
Herein, 3D honeycomb hierarchical porous network scaffold carbon is synthesized by a unique PVP-SiO2-boiling method with the boiling bubbles as soft template and SiO2 nanospheres as hard template. Then MnO2 nanosheets intimately grow on the carbon matrix and are further decomposed to Mn3O4 nanocrystalline with size of 7–9 nm. The obtained Mn3O4 nanocrystalline@3D honeycomb hierarchical porous network scaffold carbon has abundant mesopores and large specific surface area (92 m2 g−1). When used as a cathode material for zinc-ion batteries, the synthesized composites exhibit high reversible capacity (546.2 mAh g−1 at 0.5 A g−1), remarkable cycling stability (discharge capacity of 97.8 mAh g−1 at 3 A g−1 after 600 cycles) and superior rate capability (15.7 mAh g−1 at 10 A g−1). The kinetics analyses indicate zinc storage mechanism includes diffusion process and capacitive process of Zn2+ and H+ ions, and the capacitive storage is dominant. The outstanding zinc storage performance benefits from the structural advantages. The unique carbon matrix improves electronic conductivity of Mn3O4, facilitates penetration of electrolyte, and well supports Mn3O4 nanocrystalline. The small size and large specific surface area of Mn3O4 nanocrystalline induce significant capacitive storage effect.
研究领域:
材料科学
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电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Wen Xu,Shiwen Dong,Haijun Cheng,Stefanos Giannakis,Xiaohui Lu,Zhiqiao He,Da Wang,Shuang Song,Jun Ma
Mixed refractory organic wastewater containing both organic molecular and nanoparticle contrast agents poses a significant challenge for wastewater treatment. In this study, heterogeneous catalytic ozonation (HCO) technology was employed, creatively using the nanoparticle contrast agent Mn 3 O 4 /SiO 2 /C as a catalyst for the degradation of the organic molecular contrast agent iopamidol (IPM). This study aims to provide new insights and approaches to address the challenge of mixed contrast agent treatment in medical wastewater through a “treat-waste-with-waste” strategy. Mn 3 O 4 /SiO 2 /C exhibited an excellent IPM degradation efficiency, reaching 99.3 % within 30 min, compared with only 9.6 % IPM removal in the absence of catalyst ([cat] = 0.1 g L −1 , [IPM] 0 = 5 μM, [O 3 ] 0 = 3 mg L −1 , at pH 6.8 and 278 K). The Mn 3 O 4 , SiO 2 , and C in Mn 3 O 4 /SiO 2 /C were extensively integrated, and the proportion of Mn(II) in Mn 3 O 4 /SiO 2 /C was 39.9 %, as compared to 33.1 % in Mn 3 O 4 , which facilitated the generation of hydroxyl radicals. The siloxide and carbonaceous materials in Mn 3 O 4 /SiO 2 /C provided abundant sites for ozone adsorption and pollutant enrichment, promoting interfacial ozone contact with pollutants and subsequent catalytic reactions. The presence of structures such as Mn-O-Si and Mn-O-C in the material helps accelerate electron transfer, thus promoting electron capture and ozone decomposition. This strategy provides new insights for refractory pollutant elimination and serves as a guide for advancing green catalysis in water purification.
研究领域:
环境科学
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医学
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催化材料
✓ 已验证
产品关联
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2024
·
IF 8.2
Lian Xia,Andi Huang,Xiaojuan Niu,Zhen Wu,Yue Tang,Jianli Zhou,Yuangen Wu
The detrimental growth of water pollutants such as heavy metals has become a life-threatening problem in the modern era. Challenges remain in the development of rapid and accurate methods for detecting pentavalent arsenic [As(V)] in environmental water. The octahedral Mn 3 O 4 nanoparticles (NPs) did not display excellent laccase-mimicking catalytic activity, whereas the adsorbed As(V) on the surface significantly enhanced the catalytic activity. Meanwhile, the quinone imine generated from the substrates 2,4-dichlorophenol (2,4-DP) and 4-aminoantipyrine (4-AAP) catalyzed by octahedral Mn 3 O 4 NPs further quenched the carbon dots fluorescence. Thus, it is possible to establish a fast and accurate dual-mode sensor for detecting As(V). The developed dual-mode method of As(V) detection has good sensitivity and selectivity. The limit of detection for As(V) in colorimetric mode is 6.96 μg·L −1 , whereas in the fluorescent mode, it is as low as 2.56 μg·L −1 . Moreover, the detection data obtained by the dual-mode method can be validated by each other, thereby ensuring the dependability of the sensing system. The constructed dual-mode method with merits of sensitivity, speed and accuracy can offer a powerful tool for As(V) detection in environmental water. Furthermore, the application of laccase-mimicking activity in dual-mode detection provides new strategies for other environmental hazard detection.
研究领域:
环境科学
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分析化学
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纳米生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2021
·
IF 8.067
Jingqi Chen,Xianlei Hu,Haitao Gao,Shu Yan,Shoudong Chen,Xianghua Liu
Developing new electrode materials with a high specific capacity for excellent lithium-ion storage properties is very desirable. The MnCO 3 /Mn 3 O 4 nanoparticles with uniform size (about 50 nm) and shape which are wrapped with graphene have been successfully synthesized via the one-step method for anode material of lithium-ion batteries. The as-prepared graphene-wrapped MnCO 3 /Mn 3 O 4 nanocomposite exhibits remarkable electrochemical performance, including high reversible specific capacity, outstanding cycling stability, and excellent rate capability in comparison with the bare MnCO 3 and MnCO 3 /Mn 3 O 4 nanocomposite. This is because the synergistic effect of MnCO 3 and Mn 3 O 4 nanoparticles and graphene nanosheets act as both electron conductors and volume buffer layers. From the scanning electron microscopy (SEM) analysis, we confirmed that the morphology and structure of the composite are preserved after 200 cycles. This further confirms that graphene-wrapped MnCO 3 /Mn 3 O 4 nanocomposite acts as a stable template for reversible lithium-ion intercalation/deintercalation.
研究领域:
材料科学
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电化学
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能源存储
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-22
·
IF 9.429
Li Hanrui,Cai Xiaoxia,Yi Tong,Zeng Yun,Ma Jingwen,Li Lei,Pang Liaojun,Li Na,Hu Hao,Zhan Yonghua
Background Postoperative chemotherapy for gastric cancer often causes multidrug resistance (MDR), which has serious consequences for therapeutic effects. Individualized treatment based on accurate monitoring of MDR will greatly improve patient survival.Results In this article, a self-enhanced Mn3O4 nanoplatform (MPG NPs) was established, which can react with glutathione to produce Mn2+ to enhance T1-weighted magnetic resonance imaging (MRI) and mediate in vivo real-time MDR monitoring. In vitro MRI results showed that MRI signals could be enhanced in the presence of hydrogen peroxide and glutathione and at acidic pH. In vivo MRI results indicated that MPG NPs could specifically target MDR cells, thereby realizing real-time monitoring of MDR in gastric cancer. Furthermore, MPG NPs have good chemodynamic activity, which can convert the endogenous hydrogen peroxide of tumor cells into highly toxic hydroxyl radical through Fenton-like reaction at acidic pH to play the role of chemodynamic therapy. In addition, Mn3O4 can significantly enhance the chemodynamic therapy effect because of its good photothermal conversion effect. Furthermore, in situ photothermal/chemodynamic synergistic therapy obtained remarkable results, the tumors of the mice in the synergistic therapy group gradually became smaller or even disappeared.Conclusion sMPG NPs have good biocompatibility, providing a good nanoplatform for real-time monitoring and precise diagnosis and treatment of MDR in gastric cancer.Graphical Abstract
研究领域:
纳米技术
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癌症生物学
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诊疗一体化
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Aicheng Song,Zhitao Han,Xiao Yang,Mengjing Zhang,Xi Wu,Zelu Zhou,Dong Liu,Dong Ma
The high energy consumption associated with solution regeneration in amine-based CO 2 capture processes remains a major challenge for large-scale carbon capture and storage (CCS) applications. However, the addition of solid acid catalyst accelerates the slow CO 2 desorption process while reducing the energy consumption for regeneration of the amine-rich solution. Herein, we innovatively developed Mn 3 O 4 -modified SAPO-34 catalysts via impregnation, demonstrating exceptional efficacy in reducing energy consumption for CO 2 -rich monoethanolamine (MEA) solution regeneration. Mn 15 -SAPO catalyst exhibited excellent performance in catalytic desorption tests using a 5 M CO 2 -rich MEA solution at 90 °C, achieving a 31.0 % increase in CO 2 desorption rate, a 133.3 % increase in CO 2 desorption amount, and a 57.1 % reduction in solution regeneration heat duty compared to the non-catalytic process. Comprehensive characterization revealed that the optimized Mn 15 -SAPO catalyst featured abundant strong acidic sites, optimal mesoporous structure, and the redox activity of Mn 3+ /Mn 4+ species. FTIR and 13 C NMR analysis confirmed the catalytic accelerating effect of catalysts on the conversion of intermediates. A possible reaction mechanism for the catalytic desorption of CO 2 over Mn x -SAPO catalysts was discussed. Additionally, the cycling stability of Mn 15 -SAPO catalyst was also evaluated. This work demonstrated the potential of Mn 15 -SAPO catalyst in enhancing the efficiency of the amine CO 2 capture process and reducing energy consumption, which was conducive to the application of industrial CO 2 capture.
研究领域:
能源与燃料
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环境科学
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催化
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化学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2020
·
IF 5.647
Jia Liu,Jan Baeyens,Yimin Deng,Xianlu Wang,Huili Zhang
A major action to reduce CO 2 emissions is replacing fossil fuels by renewable energy sources . Matching the energy supply and demand by the mostly intermittent renewable resources (wind, solar, wave) is hence a hot topic, and energy storage has become crucial. Thermo-chemical energy storage (TCES) has a higher energy density than sensible and latent heat storage , and allows energy to be stored in the reaction products for multiple reuse and even off-site application. Design parameters are the equilibrium temperature , the reaction heat and the reaction rate, as obtained from both thermodynamic and kinetic assessments. Equilibrium temperatures of the selected metal oxides , Mn 2 O 3 /Mn 3 O 4 and Co 3 O 4 /CoO are between 1115 K and 1179 K. The present research studies both redox reactions as examples. Commercial Mn 2 O 3 and Co 3 O 4 were previously investigated in detail, and suffer from incomplete reversibility . The present study investigates the use of self-made Mn 2 O 3 and Co 3 O 4 mesoporous particles, of micrometer or nanometer scale, respectively. The average particle size of self-made Mn 2 O 3 particles is < 5 μm, with a BET surface area of 239.7 m 2 /g, and T eq of 1177 K at ambient pressure . Self-made Co 3 O 4 was of nano size, with average size of about 100 nm, a BET surface area of 54.2 m 2 /g, and T eq of 1109 K at ambient pressure. The redox reactions of these ultrafine particles are fast and nearly fully reversible. The effect of adding inert Al 2 O 3 or Fe 2 O 3 was also studied, but proven to offer no kinetic benefit, while reducing the reaction heat due to their inert additive character. The findings were used in the design of a 10 kW TCES pilot plant that is currently being tested in a concentrated solar furnace .
研究领域:
能源存储
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可再生能源
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材料科学
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化学工程
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热力学
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动力学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Menghua Liu,Haitao Wu,Qianhui Li,Hang Liu,Chongqing Chen,Fan Yin,Hua Wang,Zhengbao Zha,Fei Wang
Acetaminophen (APAP) overdose is steadily becoming the chief reason for drug-induced acute liver failure, yet limited treatment is currently clinically available. Considering that the mechanism of APAP-induced hepatotoxicity is inseparable from oxidative stress and inflammation, a biocompatible Mn 3 O 4 nanozyme mimicking superoxide dismutase (SOD) and catalase (CAT) activities and possessing reactive oxygen species (ROS)–scavenging capacity and antiapoptotic properties, is reported herein as a promising nanodrug to treat APAP-induced liver injury (AILI). Possessing bioactive enzyme–like functions, Mn 3 O 4 nanoparticles (NPs) can not only reduce the oxidative stress on the liver by decreasing ROS accumulation but also downregulate the infiltration of inflammatory macrophages that secrete proinflammatory cytokines (tumor necrosis factor-α, interleukin-1β, and interleukin-6). Notably, the bifunctional Mn 3 O 4 NPs mediate nuclear factor–erythroid 2 p45-related factor 2 signaling pathway activation and nuclear factor kappa B signaling pathway inhibition to effectively prevent the already fragile APAP-overdosed murine hepatocytes from being attacked again, thus mitigating hepatocyte apoptosis and alleviating APAP-induced liver damage. Thus, the Mn 3 O 4 nanozyme (Mn 3 O 4 NPs) evaluated in this study has potential preventive and therapeutic effects on AILI.
研究领域:
药理学
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纳米医学
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肝病学
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Regenerative Biomaterials
·
2023
·
IF 6.7
Zhang Shengqing,Cai Jinhong,Yao Yi,Huang Lanli,Zheng Li,Zhao Jinmin
Excessive reactive oxygen species (ROS)-induced mitochondrial damage has impact on osteoarthritis (OA). Nanozyme mimics as natural enzyme alternatives to scavenge excessive ROS has offered a promising strategy for OA therapy. Herein, we reported a novel mitochondrial-targeting Mn3O4/UIO-TPP nanozyme using metal-organic frameworks (MOFs) with loaded Mn3O4 as the enzyme-like active core combining mitochondria-targeting triphenylphosphine (TPP) groups to serve as ROS scavengers for therapy of OA. With sequential catalysis of superoxide dismutase (SOD)-like, catalase (CAT)-like, and hydroxyl radical (·OH) scavenging potentials, the nanozyme can target mitochondria by crossing subcellular barriers to effectively eliminate ROS to restore mitochondrial function and inhibit inflammation and chondrocyte apoptosis. It also has favorable biocompatibility and biosafety. Based on anterior cruciate ligament transection (ACLT)-induced OA joint models, this mitochondrial-targeting nanozyme effectively mitigated the inflammatory response with the Pelletier score reduction of 49.9% after 8-week therapy. This study offers a prospective approach to the design of nanomedicines for ROS-related diseases.
研究领域:
纳米医学
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骨科
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生物化学
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药学
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生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL PHYSICS LETTERS
·
2025
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IF 3.1
Siyuan Yin,Song Li,Muying Sun,Zhongsheng Wen,Juncai Sun
Transition metal oxides (TMOs) are promising high-capacity anodes for Li-ion batteries, but their low initial Coulombic efficiency (ICE) hinders practical application. Here, a Ni/Mn 3 O 4 composite was prepared via ball milling, where nano-Ni dispersion enhanced phase transition, increasing ICE from 39.7 % to 57.8 %. Nano-Ni reduced charge transfer resistance and enhanced pseudocapacitance contribution, improving kinetics. DFT calculations revealed Ni’s catalytic role in lowering the Li O bond-breaking energy barrier and suppressing irreversible phase transitions. TEM confirmed Ni-promoted Mn 3 O 4 phase transformation and accelerated early-stage reaction kinetics. This study provides a strategy for designing conversion-type anodes with high ICE and kinetics.
研究领域:
储能
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材料科学
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电化学
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纳米技术
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计算化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）