GREEN CHEMISTRY
·
2024
·
IF 9.3
Fei Li,Xiaoqian Yao,Rong Ding,Yinan Bao,Qing Zhou,Dongxia Yan,Yi Li,Junli Xu,Jiayu Xin,Xingmei Lu
Glycolysis of waste polyethylene terephthalate (PET) is a green and high-value PET recovery approach, the product of which can be used as raw materials to prepare polyurethanes. Enhancing the conversion rate and monomer selectivity of PET glycolysis through the development of efficient catalysts is crucial for reducing both the energy consumption and operational costs associated with the process. In this study, a series of deep eutectic solvents (DESs) were synthesised based on L-proline (Pro) and its derivatives and used as catalysts for the glycolysis of PET using 1,4-butanediol (BDO). Under the optimized reaction conditions (5.0 g PET, 25.0 g BDO, 2 wt% Pro/Zn(Ac)2 catalyst, 210 °C, 15 min and atmospheric pressure), PET was degraded completely, and the yield of monomeric bis(4-hydroxybutyl)terephthalate (BHBT) reached 67.1%. Based on the results of in situ-IR, 1H NMR and density functional theory (DFT), the possible catalytic mechanism of DESs synergistically promoting PET depolymerization was proposed. Finally, aromatic-based polyurethane elastomers (PUEs) were prepared with PET glycolysis products bis(2-hydroxyethyl)terephthalate (BHET) and BHBT as chain extenders. Compared with the control group, the thermal and mechanical properties of aromatic-based PUEs were improved, which proved the feasibility of high value utilization of PET glycolysis products.
研究领域:
材料科学
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化学工程
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环境科学
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 31
·14646-14655
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IF 3.3
Ruiyang Wen,Guoliang Shen,Jinmiao Zhai,Linghui Meng,Yunlong Bai
Acetylacetone titanium oxide (TiO(acac)2) was synthesized from acetylacetone and isopropyl titanate via a one-pot method. The catalyst's structure and morphology were characterized and analyzed using FT-IR, UV–vis, XRD, SEM, and laser particle size analysis. The prepared acetylacetone titanium oxide was used for the alcoholysis reaction of polyethylene terephthalate (PET), and the yield of bis(hydroxyethyl) terephthalate (BHET) obtained from the alcoholysis reaction was taken as the index. The optimal conditions for the alcoholysis reaction were determined using response surface methodology: 3 g of PET, a catalyst dosage of 0.467%, a temperature of 200.5 °C, a time of 3.77 h, and 13.50 mL of ethylene glycol, with a BHET yield of 96.41%. The model had good reliability. Finally, the reaction mechanism was speculated, and the catalyst was compared with other catalysts. The TiO(acac)2 catalyst has a good application prospect.
研究领域:
化学工程
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材料科学
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催化反应
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Zheng-Fei Yan,Chu-Qi Feng,Jian-Qiao Zhou,Qing-Song Huang,Xiao-Qian Chen,Wei Xia,Jing Wu
Enzymatic degradation has been proposed as a suitable solution for addressing PET pollution, but approximately 10 % of PET is left as nonbiodegradable. Microbes can completely degrade PET at the gram level per year. Based on the complementary benefits of microbes and enzymes , a microbe-enzyme system was created to completely degrade PET. Here, a thermophilic microbe-enzyme (TME) system composed of Bacillus thermoamylovorans JQ3 and leaf-branch compost cutinase variant (ICCG) was used to demonstrate the synergistic degradation of PET, enabling 100 % degradation of PET waste at a high PET loading level (360 g/L). Six endogenous PET hydrolases of strain JQ3 were discovered by employing an ester bond hydrolysis function-first genome mining (EGM) strategy and first successfully expressed in E. coli . These hydrolases could release TPA as the final product from PET and preferentially degraded BHET instead of MHET. Of these, carboxylesterase 39_5 and ICCG could degrade PET in a synergistic manner to generate 50 μM of TPA, which was greater than the sum of the individual treatments. Finally, the degradation pathway of the TME system was speculated to include biofilm formation, PET degradation and utilization. The successful implementation of this study rendered a scale-up degradation feasible of PET at a lower cost.
研究领域:
环境科学
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生物技术
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微生物学
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产品关联
DOI
PubMed
高影响因子
MOLECULAR PHARMACEUTICS
·
2023
·
IF 4.9
Chaoquan Lai,Rui Cao,Renda Li,Chunfeng He,Xiao Wang,Hui Shi,Chunrong Qu,Kun Qian,Shaoli Song,Wen-Hua Chen,Zhen Cheng
As an important cancer-associated fibroblast-specific biomarker, fibroblast activation protein (FAP) has become an attractive target for tumor diagnosis and treatment. However, most FAP-based radiotracers showed inadequate uptake and short retention in tumors. In this study, we designed and synthesized a novel FAP ligand (DOTA-GPFAPI-04) through assembling three functional moieties: a quinoline-based FAP inhibitor for specifically targeting FAP, a FAP substrate Gly–Pro as a linker for increasing the FAP protein interaction, and a 2,2′,2″,2‴-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (DOTA) chelator for radiolabeling with different radionuclides. The FAP targeting ability of DOTA-GPFAPI-04 was investigated by molecular docking studies. DOTA-GPFAPI-04 was then radiolabeled with 68Ga to give [68Ga]Ga-DOTA-GPFAPI-04 for positron emission tomography (PET) imaging of glioblastoma. [68Ga]Ga-DOTA-GPFAPI-04 exhibited a purity of >98% and high stability analyzed by radio-HPLC in saline and mouse serum. Cell uptake studies demonstrated the targeting specificity of the probe. Further in vivo pharmacokinetic studies in normal mice demonstrated the quick clearance of the probe. Moreover, compared with the widely studied [68Ga]Ga-FAPI-04, [68Ga]Ga-DOTA-GPFAPI-04 showed much higher U87MG tumor uptake values (4.467 ± 0.379 for [68Ga]Ga-DOTA-GPFAPI-04 and 1.267 ± 0.208% ID/g for [68Ga]Ga-FAPI-04 at 0.5 h post-injection, respectively). The area under the curve based on time–activity curve (TAC) analysis for tumor radioactivity in small animal models was 422.5 for [68Ga]Ga-DOTA-GPFAPI-04 and 98.14 for [68Ga]Ga-FAPI-04, respectively, demonstrating that the former had longer tumor retention time. The tumor-to-muscle (T/M) ratio for [68Ga]Ga-DOTA-GPFAPI-04 reached 9.15 in a U87MG xenograft animal model. PET imaging and blocking assays showed that [68Ga]Ga-DOTA-GPFAPI-04 had specific tumor uptake. In summary, this study demonstrates the successful synthesis and evaluation of a novel FAPI targeting probe, [68Ga]Ga-DOTA-GPFAPI-04, with a Gly–Pro sequence. It shows favorable in vivo glioblastoma imaging properties and relatively long tumor retention, highlighting DOTA-GPFAPI-04 as a promising molecular scaffold for developing FAP targeting tumor theranostic agents.
研究领域:
医学影像学
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肿瘤学
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分子生物学
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DOI
PubMed
高影响因子
Catalysis Science & Technology
·
2023
·Vol. 13
·期 20
·5868-5879
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IF 5
Guixiang Peng,Xueyang Qi,Wenbin Qu,Xiaoli Shao,Lixin Song,Pingfan Du,Jie Xiong
As a new type of pollutant, microplastics, especially microfibers in textiles, pose a great threat to the environment and human health. It remains challenging to remove such emerging organic pollutants. Photocatalytic technology is an effective strategy for H2 fuel production and pollutant reuse using solar energy due to its low cost and environmental friendliness. In this work, the flexible Ni5P4/TiO2/C nanofiber (NF) film photocatalysts were fabricated by electrospinning, hydrothermal treatment and low-temperature phosphating. With the addition of Ni5P4 onto TiO2/C NFs, the light absorption of composite nanofibers was improved, restraining the recombination of carriers simultaneously. Accordingly, the photocatalytic activity of the NFs was improved. The hydrogen evolution of the Ni5P4/TiO2/C NFs for photocatalytic degradation of PET microfibers reached 76.66 μmolH2 gsub−1 in 12 h, which is three times that of TiO2/C NFs. The weight loss rate of PET microfibers reached 6.23% after Ni5P4/TiO2/C NF catalysis, which was nearly 5 times higher than that without a catalyst (1.2%). In addition, the nanofiber film is easy to recycle and avoids secondary pollution. This work provides new ideas for achieving the goal of reducing microplastic fibers and microplastics in an efficient and environmentally friendly way.
研究领域:
环境科学
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材料科学
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能源科学
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
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IF 7.2
Lulu Deng,Shuang Yang,Hailong He,Jie Chen,Chenyuan Zhang,Zhongqi Liu,Lei Wang
The extensive production and utilization of polyethylene terephthalate (PET) products results in significant environmental pollution and waste of resources. This has focused global attention on the development of radical PET waste management strategies. Solvent-based dissolution and precipitation is a promising approach for recovering plastic from waste due to its “polymer-to-polymer” principle. However, most solvents currently used are toxic and not environmentally friendly. Herein, we have screened a bio-based solvent via Hansen Solubility Parameters (HSPs) and Conductor-like Screening Model for Real Solvents (COSMO-RS), dimethyl isosorbide (DMI), and applied it to PET recovery. DMI showed a favorable solubility (0.30 g mL −1 ) of PET in 8 min at 180 °C. Nuclear magnetic resonance (NMR) analysis and molecular dynamic (MD) simulation were combined to reveal the hydrogen bonding interaction and van der Waals interactions together contribute to the excellent PET dissolution performance. Moreover, the properties of recycled PET were similar to those of virgin PET, with minimal degradation (∼1.25 %) and negligible loss of thermal performance. DMI has satisfactory dissolution performance in Polystyrene (PS), Polyvinyl Chloride (PVC), and polylactic acid (PLA) and can effectively separate mixture plastics and multilayer films by reaction temperature-controlled and select solubility. Additives can be released to the solution system by the accessibility of the DMI, and separation from R-PET with ethanol rinse. This work provides an energy-efficient, and solvent-based process for recycling plastic waste to produce virgin-quality PET as secondary raw materials to adapt to market demand while reducing the consumption of fossil resources.
研究领域:
材料科学
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环境科学
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化学工程
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产品关联
DOI
高影响因子
Analytical Methods
·
2019
·Vol. 11
·期 19
·2579-2584
·
IF 2.378
Dongjian Zhu,Xiaowei Yan,Aishan Ren,Wen Cai,Zhenhua Duan,Yanghe Luo
A novel ratiometric fluorescent probe 1 based on boranil derivatives modulated by ICT and PET processes was designed and synthesized for the first time. Upon addition of Cys, the emission peak of 1 changed from 461 nm to 474 nm, accompanied by a fluorescence color change from dark blue to blue under illumination with a 365 nm UV lamp. 1 exhibited a fast response (within 9 min), high sensitivity (detection limit of 95.1 nM) and excellent selectivity toward Cys over Hcy and GSH owing to a specific conjugate addition–cyclization reaction between Cys and the acrylate moiety. Furthermore, 1 was successfully implemented for monitoring Cys in living cells.
研究领域:
分析化学
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生物医学
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DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Zichen Wang,Yao Dai,Yumeng Wang,Peilu Zhang,Lin Zhou,Yuan Jiang,Ruoke Liu,Sarah Elfadil Ali Adam,Chao Sun,Xiaochun Chen
Polyethylene glycol terephthalate (PET) is widely utilized in industrial applications and everyday life. However, its extensive use has led to substantial environmental challenges. This study presents a highly active and selective [DBU][m-cresol] proton-ionic liquid (PIL)-immobilized ZIF-8 catalyst for PET resource utilization. Using just 15 mg of the ZIF-8@[DBU][m-cresol]-2 catalyst, PET degradation reached 97.72 %, while BHET conversion achieved 86.95 % within 60 min. The Zn 2+ ions in the catalyst decrease the electron density of the m-cresol carbocation, thus improving the nucleophilic substitution capability of [DBU][m-cresol]. The influence of catalyst dosage, the ethylene glycol-to-PET ratio, and temperature on degradation and conversion was investigated. After five cycles, the catalyst retained a degradation efficiency of 77.71%. In practical applications, testing on three commercial PET materials demonstrated degradation efficiencies exceeding 90%. DFT calculations and LC-MS analysis indicate that hydrogen bonding among ethylene glycol (EG), PET, and ZIF-8@[DBU][m-cresol] enhances PET’s electrophilicity, while Zn 2+ decreases the electron density of carbocations, thereby facilitating PET degradation. This work highlights the potential of proton-based ionic liquid-supported catalysts for efficiently converting PET waste into valuable resources.
研究领域:
环境科学
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材料科学
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化学工程
✓ 已验证
DOI
高影响因子
BIOORGANIC CHEMISTRY
·
2025
·
IF 4.7
Jingyao Gong,Yunlong Li,Hui Di,Jiamin Li,Junming Dong,Congjie He,Peng Cao,Huiming Cai,Jian He,Yiqing Wang
Combination of PET and optical imaging techniques holds significant potential for complete tumor resection to optimize patient outcomes. In this study, we combined two lapatinib-based molecular probes for detecting HER2-overexoression tumors through PET and near-infrared (NIR) fluorescence imaging. HER2 receptor had been confirmed to be overexpressed in many types of tumors and had become a specific target for molecular imaging. The radiolabeled probe [ 68 Ga] Ga-NOTA-lapatinib demonstrated superior imaging performance in micro-PET scans, achieving clear differentiation of subcutaneous tumors from adjacent tissues. Complementarily, the NIR fluorescent probe LP-S exhibited prolonged tumor retention (>72 h) with distinct signal demarcation between malignant and normal tissues in ex vivo analyses. Fluorescence microscopy further validated specific intra-tumoral accumulation of the probe at cellular resolution. This synchronized dual-probe strategy, leveraging identical targeting moieties, established a robust platform for multimodality cancer imaging that bridges preoperative detection with intraoperative visualization.
研究领域:
医学影像学
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分子生物学
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肿瘤学
✓ 已验证
DOI
PubMed
高影响因子
POLYMER BULLETIN
·
2022
·Vol. 79
·期 12
·10573-10593
·
IF 2.843
Zhong Wen,Wei Binxiao,Wang Yu,Bai Yongping
Polyacrylate coating has been used for modifying Polyethylene terephthalate (PET) film to improve its oxygen barrier performance. However, comprehensive study on the oxygen barrier of polyacrylate coating is still underway. In this work, a series of polyacrylate coatings with different functional monomers such as maleic acid (MA), acrylic acid (AA), 2-hydroxyethyl acrylate (2-HEA), and 2-butene-1, 4-diol (1, 4-BED) were prepared by using Desmodur L75 (L75) and Erisys Ga240 (Ga240) as a curing agent. The polyacrylate coatings were characterized by Fourier Transform Infrared (FT-IR) spectrometer. The oxygen permeability (Po 2 ) of the coatings was measured by Gas Permeability Tester. The results reveal that anhydride moiety produced by dehydration of carboxylic acid is the key structure for enhancing the oxygen barrier property of the polyacrylate coating. Moreover, when the anhydride coexists with other cross-linking structures, the oxygen barrier performance of the resulting coatings was not further enhanced. Compared with the pristine PET substrate, the anhydride-containing polyacrylate-coated PET film has reduced Po 2 by 68%. This work provides a facile strategy for improving the oxygen barrier performance of PET film by coating amorphous polyacrylate.
研究领域:
材料科学
·
高分子化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Chunrui Rong,Dongxia Yan,Jiabao Li,Jian Feng,Jiayu Xin,Qing Zhou,Yi Li,Junli Xu,Xingmei Lu
The increase in the usage of polyethylene terephthalate (PET) leads to the generation of a large amount of waste, which may cause carbon emissions and waste of petroleum resources. The methanolysis method has attracted global attention, but limited by high reaction temperature and excessive use of methanol. We report here an efficient catalyst, tetramethylguanidine/1,5-diazabicyclo[4.3.0]-5-non-ene (TMG/DBN), converting waste PET into regenerated dimethyl terephthalate (rDMT) under 100 °C with almost equivalent methanol, achieving 100 % PET conversion and 93.1 % yield of rDMT. A series of analytical methods and theoretical calculations were used to reveal the enhanced interaction between the catalyst and reactants, which facilitates the degradation of PET at low methanol dosages. In addition, a kinetic model was also developed with a relatively low activation energy of 84.9 kJ/mol. This work provides an effective strategy for the up-grading recycling of waste PET under mild reaction conditions.
研究领域:
材料科学
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环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2018
·Vol. 136
·期 16
·47299
·
IF 1.901
Jianrong Xia,Yumiao Su,Wenmu Li
Concerns about the rising trend of stringent fire safety regulations and demands for reduction in the fire hazard call for a careful evaluation of the environmental impact of flame retardant materials choices. With the worldwide bans and restrictions in the use of traditional halogen-based fire retardant systems, phosphorus/nitrogen synergistic flame retardants became evident. We report here a novel phosphorus- and nitrogen-containing polyether (PN-PEO) prepared by post-polymerization functionalization. The resultant polyethers (PN-PEO) were subsequently coated onto the surface of poly(ethylene terephthalate) (PET) fabrics by a simple solution-dipping method to exploit a highly efficient fire retardant. It was found that the loadings of 17.8% PN-PEO had a strong barrier effect in the char layer of the PN-POE-coated PET fabrics after exposed to the torch flame, and resulted in complete suppression of PET fabrics ignition on radiant heat exposure. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136 , 47299.
研究领域:
材料科学
·
纺织工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）