RSC Advances
·
2015
·Vol. 5
·期 111
·91218-91224
·
IF 3.84
Sufeng Wang,Mengxuan Ma,Wencang Man,Qingrui Zhang,Xiaolong Niu,Guiqing Sun,Wen Zhang,Tifeng Jiao
Phosphate is a worldwide environmental issue, due to possibly causing serious eutrophication and subsequently blue-green algae blooms. Sequestrating phosphate by exploitation of advanced materials with a hierarchical morphology will be an important pathway. Herein, we fabricated a new sea urchin-like zirconium(IV) oxide (Ur-Zr) using a one step facile alcoholysis solvothermal reaction for efficient phosphate removal. The as-obtained material exhibits adsorption properties in a wide range of pH conditions with the optimal pH ranging from 1.0 to 6.0; competition results reveal that the Ur-Zr displays remarkable sorption selectivity for phosphate removal with coexisting common anions (SO42−, NO3− and Cl− ions) at high concentrations, which can be ascribed to the unique hierarchical morphology and strong sorption affinity between Zr–O and phosphate species. Besides, the resultant Ur-Zr also shows a gradual sorption kinetics behavior, which can be well described by the pseudo-first-order model with the maximum sorption capacity of 74.8 mg g−1. Additionally, the exhausted materials can be recycled by alkaline treatment and used repeatedly. All of the results demonstrate that the sea urchin-like zirconium(IV) oxide is a competent candidate for enhanced phosphate removal.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
FOOD BIOTECHNOLOGY
·
2016
·
IF 0.814
Ming-Ming Zhu,Shu-Lin Wang,Ming-Tao Fan
This study was designed to isolate and identify a novel β-carotene cleaving microorganism from sea buckthorn juice and to detect the carotenoid-derived aroma compounds catalyzed by the microbial enzyme. The strain was characterized based on morphological and biochemical properties, as well as part of its 16S rDNA sequence analysis. It was then identified using Basic Local Alignment Search Tool (BLAST) and classified as coagulase-negative Staphylococcus pasteuri (GeneBank Accession No. KP171185). β-Ionone and β-cyclocitral were formed as the main flavor products of β-carotene in submerged culture. When cell-free culture supernatant was applied for the conversion, nearly complete degradation of β-carotene (2 mg) was observed after 12 h. β-Ionone and β-cyclocitral were the main aromas, whereas β-ionone-5,6-epoxide, 2-hydroxy-2,6,6-trimethyl cyclohexanone and dihydroactinidiolide were formed in minor quantities. Moreover, the carotenoid-cleavage enzyme activities of S. pasteuri were partially characterized and partially purified enzyme possesses high activity in adverse industrial condition.
研究领域:
微生物学
·
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
Nutrients
·
2022
·Vol. 14
·期 4
·786
·
IF 6.706
Ruizhen Ru,Yanzheng Guo,Juanxuan Mao,Zonghe Yu,Wen Huang,Xudong Cao,Huijian Hu,Minjie Meng,Lihong Yuan
Cancer remains the primary cause of death worldwide. To develop less toxic anti-cancer drugs to relieve the suffering and improve the survival of cancer patients is the major focus in the anti-cancer field. To this end, marine creatures are being extensively studied for their anti-cancer effects, since extracts from at least 10% of the marine organisms have been shown to possess anti-tumor activities. As a classic Chinese traditional medicine, sea cucumbers and compounds extracted from the sea cucumbers, such as polysaccharides and saponins, have recently been shown to exhibit anti-cancer, anti-inflammatory, and anti-oxidant effects.Holothuria leucospilota(H. leucospilota) is a tropical edible sea cucumber species that has been successfully cultivated and farmed in large scales, providing a readily available source of raw materials to support the development of novel marine anti-cancer drugs. However, very few studies have so far been performed on the biological activities ofH. leucospilota. In this study, we first investigated the anti-cancer effect ofH. leucospilotaprotein on three cancer cell lines (i.e., HepG2, A549, Panc02) and three normal cell lines (NIH-3T3, HaCaT, 16HBE). Our data showed thatH. leucospilotaprotein decreased the cell viabilities of HepG2, A549, HaCaT, 16HBE in a concentration-dependent manner, while Panc02 and NIH-3T3 in a time- and concentration-dependent manner. We also found that the inhibitory effect ofH. leucospilotaprotein (≥10 μg/mL) on cell viability is near or even superior to EPI, a clinical chemotherapeutic agent. In addition, our data also demonstrated thatH. leucospilotaprotein significantly affected the cell cycle and induced apoptosis in the three cancer cell lines investigated; in comparison, it showed no effects on the normal cell lines (i.e., NIH-3T3, HaCaT and 16HBE). Finally, our results also showed thatH. leucospilotaprotein exhibited the excellent performance in inhibiting cell immigrations. In conclusion,H. leucospilotaprotein targeted the cancer cell cycles and induced cancer cell apoptosis; its superiority to inhibit cancer cell migration compared with EPI, shows the potential as a promising anti-cancer drug.Keywords:sea cucumber protein;anti-cancer activity;targeted effects;cell apoptosis;cell migration;marine extractions
研究领域:
肿瘤学
·
海洋生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Aquatic Food Product Technology
·
2020
·
IF 1.02
Yan-Fei Liu,Zi-Xuan Wu,Jing Zhang,Yu-Xin Liu,Zhong-Yuan Liu,Hong-Kai Xie,Kanyasiri Rakariyatham,Da-Yong Zhou
Lipid profile of the oyster Crassostrea talienwhanensis from the Yellow Sea was evaluated based on the seasonal changes in lipid categories, phospholipid (PL) categories, fatty acid (FA) composition, atherogenicity index (IA), thrombogenicity index (IT), and glycerophospholipid (GP) molecular species. We observed that the samples harvested in February contained higher levels of polyunsaturated fatty acid (PUFA) (48.77% of total FAs) and PL (52.12% of total lipids) and had lower IA (0.29). In addition, more than 290 GP molecular species of glycerophosphocholine (GPCho), glycerophosphoethanolamine (GPEtn), glycerophosphoserine (GPSer), and glycerophosphoinositol (GPIns) were determined. The molecular species containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) constituted 75.24% of total GPCho in the samples harvested in February. Considering the lipid profile, oyster Crassostrea talienwhanensis harvested in February had better nutritional value.
研究领域:
营养学
·
海洋生物学
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Ronghua Yin,Ying Pan,Ying Cai,Fan Yang,Na Gao,Dilihumaer Ruzemaimaiti,Jinhua Zhao
Fucosylated chondroitin sulfate (FCS) from sea cucumber Ludwigothurea grisea (FCS Lg ) is the first one that reported to bear the di-fucosyl branches. Here we deciphered it by analyzing the physicochemical properties and its derivatives. Oligosaccharides prepared by selective cleavage of glycosidic linkages presented the mono-fucose and heterodisaccharide branches in FCS Lg . The disaccharide branch was determined as d -GalNAc R1 -(α1,2)- l -Fuc R2 rather than the di-fucosyl branch, where R1 was 4-mono-O- or 4,6-di-O-sulfation, and R2 was 3-mono-O- or 3,4-di-O-sulfation, respectively. The diversity of sulfation patterns in branches complicated the structure. These results give us a new understanding of FCS Lg and provided a reliable method to decipher the FCS with complex branches. Bioanalysis of chemically modified derivatives showed that modulating the molecular mass could enhance the Xase target selectivity. Side chains conferred the Xase complex inhibition by binding to FIXa with a high affinity. Whether monosaccharide and disaccharide branches have differential effects needs to be further explored.
研究领域:
生物化学
·
海洋生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Aquatic Food Product Technology
·
2023
·
IF 1.6
Jie Zheng,Hao Ding,Lirong Bai,Shuai Zhu,Hongyuan Hui,Xinyue Zhu,Wen Chen,Aijun Hu
The Chinese traditional food, fermented semi-dried sea bass (FSSB), is famous for its unique flavor. The microbiota succession and flavor formation during fermentation remain unknown. This study utilized high-throughput sequencing to investigate the evolving microbiota and chemical determination to explore volatile compounds. The relevant abundance of microorganisms in the middle-fermented stage was significantly (p <.05) higher than that of the post-fermented stage. In addition, the main microbial phyla during fermentation were Firmicutes and Proteobacteria. In conclusion, this study contributes to understanding the changes in flavor substances during fermentation and the varying patterns of change among different floras.
研究领域:
食品科学
·
微生物学
·
化学分析
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2023
·
IF 3.3
Dongping Huang,Peng Yong,Shuifa Shen
The sea urchin-like In 2 O 3 material was successfully synthesized through a simple hydrothermal method . Furthermore, the material underwent surface decoration without adding extra indium ions , resulting in the formation of a thin MIL-68(In) layer on the surface of In 2 O 3 . The obtained In 2 O 3 @MIL-68(In) retains the sea urchin-like morphology while acquiring an additional porous structure. Compared to pure In 2 O 3 , the composite exhibits a significant increase in specific surface area, leading to enhanced gas sensitivity. Notably, it demonstrates exceptional sensitivity towards formaldehyde gas, with a response of 18 at 100 ppm at 300 °C, up to six times more than pure In 2 O 3 . Moreover, In 2 O 3 @MIL-68(In) showcases remarkable selectivity and stability. These findings suggest that surface-modified MOF can enhance gas-sensitive properties.
研究领域:
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Polymer Materials
·
2023
·
IF 5
Xiaowen Wang,Wenhao Wang,Huibin Liu,Qinghao Guo,Haibo Yu,Zheng Yuan,Wenguang Yang
Due to the reversible ability of hydrogels to absorb and lose water, more and more researchers are applying hydrogels to the research of underwater robots. Sea anemones are soft marine creatures with simple structures and soft bodies, whose extended tentacles shrink in response to danger or capture of food. Inspired by sea anemones, we built a light-driven bilayer gripper to complete the process of catching and releasing. In addition, a bionic sea anemone actuator composed of a magnetic-driven flower stalk and a light-driven flower was designed. Under the effect of an external magnetic field, the bionic sea anemone can wiggle, mimicking the sea anemone’s drift through the water. The light-driven flower has superior programmability and fast response, simulating the contraction of sea anemone when stimulated. In addition, the flower stem of sea anemone can bend to capture prey. The flower stem of the bionic sea anemone introduced is photo-responsive, which can bend in different directions under unilateral light irradiation. This study combines light drive and magnetic drive, providing a reference value for underwater drive of actuators.
研究领域:
软体机器人
·
材料科学
·
仿生学
✓ 已验证
产品关联
DOI
高影响因子
ANALYST
·
2025
·
IF 3.3
Die Hu,Jiawen Xiang,Jingying Guo,Chao Wang,Ji Qi,Bowei Li,Xiaoyan Wang,Xin Zhang,Lingxin Chen,Xuming Zhuang
In this study, we developed a simple and cost-effective paper and cloth-based microfluidic fluorescence sensing device for the selective and quantitative detection of L-cysteine (L-Cys) in deep-sea water, addressing the need for efficient monitoring of this critical metabolite of deep-sea creature’s biomarker. The device employs gold nanoparticles (Au NPs) immobilized on a cloth-based substrate and Rhodamine B (Rh B) molecules. In the presence of L-Cys, strong interactions between L-Cys and the Au NPs release Rh B molecules, restoring fluorescence proportional to the cysteine concentration. The device achieves a low detection limit of 0.52 nM with a dynamic range of 1-100 nM. It demonstrates excellent selectivity over other amino acids, stability over 30 days, and reproducibility. Its practical applicability was confirmed using deep-sea cold seep water samples, yielding recoveries of 98.07%-102.62%. Compared to existing methods, this platform offers enhanced portability, lower cost, and faster response, making it suitable for in-situ environmental monitoring.
研究领域:
分析化学
·
环境科学
·
海洋生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Muhammad Usman Amin,Haichao Zhai,Yupeng Yuan,Liteng Ren,Chuhong Zhu
Surface-enhanced Raman scattering (SERS) has gained significant attention in various fields, including biomedical diagnostics, environmental monitoring, and food safety. This technique offers many advantages such as label-free detection and the ability to detect analytes at low concentrations. In this study, we present a variety of tungsten oxide (W 18 O 49 ) microstructures as solid SERS substrates using various solvents realized by a simple hydrothermal approach. Among them, the well-defined sea urchin-like W 18 O 49 microstructures support greater light scattering and confinement to enhance the SERS signal when compared to other W 18 O 49 structures. The surface of well-defined sea urchin-like W 18 O 49 microstructures was then modified with uniformly distributed silver nanoparticles (Ag NPs). The combination of the unique morphology of the Ag and sea urchin-like W 18 O 49 microstructures (W 18 O 49 @Ag) led to improved detection capabilities for analytes such as rhodamine 6 G (R6G) and thiram molecules. The SERS enhancement factor (EF) of sea urchin-like W 18 O 49 @Ag microstructures was estimated to be as high as 1.53×10 6 with the lowest detectable concentrations of 1 nM and 1 μM for R6G and thiram, respectively. Thus, the well-defined sea urchin-like W 18 O 49 @Ag microstructures are excellent choice to replace the pure noble metal SERS substrates in the fields of rapid detection and trace analysis due to their high sensitivity, repeatability, and long-term stability.
研究领域:
材料科学
·
分析化学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
MARINE POLLUTION BULLETIN
·
2025
·
IF 4.9
Shuai Sun,Xing Liu,Wenbin Yuan,Yun Luo,Xiumei Sun,Yanhui Ao,Lei Wang,Ningbo Geng
Benzotriazole ultraviolet absorbers (BUAs) are regarded as emerging contaminants due to their persistent, bioaccumulative, and toxic (PBT) or very persistent and very bioaccumulative (vPvB) properties, raising concerns about their presence in aquatic environments. This study explored BUAs in the northwest nearshore of the East China Sea, revealing their prevalent occurrence in both seawater and sediments. The total concentrations of eight BUAs ranged from 4.96 to 620 ng/L in seawater and from 7.41 to 131 ng/g dry weight in sediments. Their distribution between sediments and seawater was basically dependent on log K ow, though UV-P presented an unusual preference for sediment due to its lower steric hindrance. Environmental factors had limited effects on BUAs distribution, and their decreasing concentrations from nearshore to offshore indicate terrestrial inputs and coastal anthropogenic activities are the primary sources of marine BUAs. Results of the initial ecological risk assessment suggested the occurrence of BUAs may pose potential ecological risks to the local marine environments. This study provides an overview of BUAs spatial distribution in the northwest nearshore of the East China Sea, emphasizing the urgent need for toxicological studies to fully understand their potential risks and establish regulatory measures for mitigating coastal pollution.
研究领域:
环境科学
·
海洋环境学
·
污染物生态毒理学
·
环境化学
·
近岸生态系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
eLife
·
2023
·
IF 7.7
Wenjie Xu,Chenglong Zhu,Xueli Gao,Baosheng Wu,Han Xu,Mingliang Hu,Honghui Zeng,Xiaoni Gan,Chenguang Feng,Jiangmin Zheng,Jing Bo,Li-Sheng He,Qiang Qiu,Wen Wang,Shunping He,Kun Wang
As the deepest vertebrate in the ocean, the hadal snailfish (Pseudoliparis swirei), which lives at a depth of 6,000–8,000 m, is a representative case for studying adaptation to extreme environments. Despite some preliminary studies on this species in recent years, including their loss of pigmentation, visual and skeletal calcification genes, and the role of trimethylamine N-oxide in adaptation to high-hydrostatic pressure, it is still unknown how they evolved and why they are among the few vertebrate species that have successfully adapted to the deep-sea environment. Using genomic data from different trenches, we found that the hadal snailfish may have entered and fully adapted to such extreme environments only in the last few million years. Meanwhile, phylogenetic relationships show that they spread into different trenches in the Pacific Ocean within a million years. Comparative genomic analysis has also revealed that the genes associated with perception, circadian rhythms, and metabolism have been extensively modified in the hadal snailfish to adapt to its unique environment. More importantly, the tandem duplication of a gene encoding ferritin significantly increased their tolerance to reactive oxygen species, which may be one of the important factors in their adaptation to high-hydrostatic pressure.
研究领域:
海洋生物学
·
比较基因组学
·
进化生物学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）