CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jinye Hu,Wenguang Zhou,Yunpu Wang,Haiwei Jiang,Jiabo Wu,Ting Luo,Mengjiao Wang,Weixin Wang,Qi Wang,Yuhang Hu,Liangliang Fan
HZSM-5 widely used for the catalytic pyrolysis of biomass exhibits the drawbacks of high diffusion resistance and large coke production. To effectively enhance the catalytic efficiency and alleviate the coke deposition, a novel promising catalyst, HZSM-5 coated activated carbon (HZSM-5@AC), was prepared for the first time for in-line upgrading the pyrolysis products of soybean straw. Various catalysts including HZSM-5, activated carbon, and the HZSM-5@AC catalysts with different HZSM-5 to activated carbon mass ratios were characterized. The results showed that the HZSM-5 was successfully coated on the surface of activated carbon and the addition of activated carbon introduced a mesoporous structure and more acidic sites to the catalyst. The catalytic performance on the biomass conversion showed that the catalyst with HZSM-5-to-activated carbon mass ratio of 18:5 (18HZSM-5@5AC) had the highest catalytic efficiency on the conversion of biomass into aromatics with a selectivity of 99.5%, including 75.68% of benzene, toluene, and xylenes (BTX) with a yield of 74.68 mg/g. Moreover, a possible pathway for HZSM-5@AC catalyzed biomass pyrolysis was proposed through analyzing the conversion of model compounds. The catalyst cycling experiments demonstrated the higher stability of HZSM-5@AC than the parent HZSM-5 and activated carbon. TG, FTIR, Raman and SEM showed that the spent HZSM-5@AC was hardly structurally changed with a low coke yield of 0.08%. However, the spent HZSM-5 was partly structurally deactivated by large aromatic ring systems with a coke yield of 3.74%. SEM results also showed that a large amount of polymerized material encapsulated the surface of the spent HZSM-5.
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CATALYSIS LETTERS
·
2024
·
IF 2.3
Xu Xian,Lan Ling,Xu Jiangong,Liang Zheng,Tan Jin,Wang Haiyong,Qiu Songbai
The development of biodegradable materials from biomass is a crucial strategy for leveraging biomass resources. A key component in this process is 2,5-bis(hydroxymethyl)furan (BHMF), a significant biomass-derived platform chemical. However, producing BHMF with high selectivity through the selective hydrogenation of 5-hydroxymethylfurfural, while avoiding the creation of unwanted byproducts, is a complex challenge. In our research, we have developed a novel catalyst featuring a magnetic core. This catalyst, which consists of platinum loaded onto a graphene-like shell, has been applied to the catalytic hydrogenation of HMF in an aqueous environment. Under the optimized conditions of 373 K, 3 MPa H 2 , and 1 h reaction time, a BHMF yield exceeding 99% was achieved. This method presents a promising and effective approach for the high-value conversion of biomass waste into polymer materials and pharmaceutical chemicals. Graphical Abstract
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Journal of Physical Chemistry C
·
2025
·
IF 3.2
Hao Yuan,Xiaoxue Han,Zhizheng Sheng,Jian Zhou,Zhendong Wang,Yingchun Ye,Yongfeng Hu,Weimin Yang
Zeolites have been widely employed in industrial catalysis, but the application of zeolites was often limited by their hydrothermal stability. As a successfully applied method for enhancing hydrothermal stability of zeolites, phosphorus (P) modification has been faced with issues such as polymerization and low utilization of P precursor. In this work, we developed a strategy for the P modification of zeolites via trimethylphosphine oxide (TMPO) selective adsorption. Thanks to its alkaline property, TMPO could be adsorbed selectively on the acid sites of zeolites and maintains strong interaction with framework aluminum during further redistribution and oxidation treatments. Extensive characterizations, such as 27Al and 31P MAS NMR, pyridine-FTIR, and P K-edge XANES, were employed to study the transformation of P–Al interaction in zeolites during hydrothermal treatment. It was revealed that the P species adsorbed on strong acid sites were beneficial to the production of a stronger P–Al interaction. Hydrothermal experimental results proved that the P-modified zeolites with a stronger P–Al interaction exhibited higher retention of Bro̷nsted acid sites, resulting from the greatly reduced polymerization of P to protect more framework aluminum. Our approach demonstrates the potential of TMPO modification in controlling P–Al interaction to enhance the hydrothermal stability of zeolites for the methanol to hydrocarbon reaction.
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ENERGY & FUELS
·
2025
·
IF 5.3
Haoyu Liu,Yanlin Wang,Hong Yuan
The introduction of mesopores to zeolite crystals via small organic templates has attracted widespread attention. In this study, we used cetylpyridinium bromide (CET–PyBr) to direct the synthesis of hierarchical meso-microporous ZSM-5 zeolite (HMM). By varying the CET–PyBr and sodium sulfate contents in the initial gel, the pore structure and acidity of the HMM were systematically modified. X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and N2 adsorption/desorption were utilized to investigate HMM’s mesoporous network. In HMM, mesopore formation was attributed to the assembly of nanocrystal clusters. By optimizing the organic templates, the HMM formation mechanism was elucidated. The acidities of the HMM catalysts were further characterized using temperature-programmed ammonia desorption, magic angle spinning nuclear magnetic resonance, and Py-IR spectroscopy. At 500 °C, the catalytic cracking of oleic acid over HMM yielded up to 54.0% light olefins, and HMM maintained its activity for up to 40 h. HMM’s homogeneous mesopores and moderate acidity contributed to its extended lifespan and enhanced its gaseous product yield.
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NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Wenpeng Han,Shujuan Wang,Fujiang Geng,Lei Liu,Ruidi Wei,Mingxing Tang
An efficient and selective nickel-molybdenum nitride catalyst has been developed for the hydrogenolysis of 5-hydroxymethylfurfural (HMF) to produce 2,5-dimethylfuran (DMF). The results showed that Ni2Mo3N phase of the catalyst exhibited good hydrogenation activity for HMF, while Ni6Mo6C1.06 phase demonstrated effective C-O bond hydrogenolysis activity. By regulating the Ni/Mo molar ratios, the proportions of the Ni2Mo3N and Ni6Mo6C1.06 phases can be adjusted, and the NiMoNx (Ni:Mo=1:2) catalyst with good performance was prepared. Additionally, 2-propanol, as a good solvent, can react with HMF to form ethers, facilitating easier hydrogenolysis. This method leads to full conversion of HMF, achieving a 99% yield of DMF at 160 oC and 2 MPa H2 for 5 h. Furthermore, the catalyst displayed good recyclability, maintaining its activity over 4 cycles, indicating it has the potential application for the industrialization of 5-HMF hydrogenolysis to produce DMF.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yuhui Huang,Yehan Tao,Xifan Yuan,Jinwen Hu,Jian Du,Chenglong Fu,Jie Lu,Yanna Lv,Haisong Wang
Cobalt-based catalysts have demonstrated significant potential for the selective electrooxidation of biomass-derived 5-hydroxymethylfurfural (5-HMF) into high-value 2,5-furandicarboxylic acid (FDCA). However, monometallic systems suffer from sluggish redox kinetics of cobalt species and insufficient reactant adsorption. In this study, we address these limitations by constructing a niobium oxide-supported cobalt‑copper bimetallic catalyst (CoCu/Nb₂O₅), leveraging bimetallic synergy and interface engineering to enhance catalytic activity. The incorporation of copper species facilitates efficient electron transfer between cobalt species of different valence states, while the Nb₂O₅ support strengthens electronic interactions with 5-HMF molecules and enables lattice oxygen participation in the reaction. Furthermore, the porous structure of the support improves bimetallic dispersion and provides enhanced mass transport pathways. The optimized CoCu/Nb₂O₅ catalyst achieves complete 5-HMF conversion and a remarkable 98.3 % FDCA yield at 1.4 V vs RHE, alongside excellent stability and reusability. Additionally, the catalyst demonstrates versatility by efficiently converting furfural into furoic acid, another biomass-derived platform molecule. This work offers valuable insights for designing advanced cobalt-based electrocatalysts and promotes the valorization of biomass resources.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Mengze Gong,Lingyu Jia,Shanshan Dang,Tianliang Lu,Peng Wang,Weifeng Tu,Zhenzhou Zhang
The catalytic conversion of biomass-derived 5-hydroxymethylfurfural (HMF) into high-value-added products, such as 2,5-bis(hydroxymethyl)furan (BHMF) and 2,5-bis(hydroxymethyl)tetrahydrofuran (BHMTHF) has attracted considerable attention. Among this process, controlling the distribution of the catalytic products plays a vital role. In this paper, NiCe and NiZnCe catalysts were prepared by the sol-gel method. By optimizing the metal loading amount and reaction conditions, a selectivity of 95.3 % to BHMTHF with the NiCe catalyst and a selectivity of 94.1 % to BHMF with the NiZn 0.1 Ce catalyst were achieved. Characterization results demonstrated that the addition of Zn causes electrons to transfer from Zn to Ni and increases the content of oxygen vacancies on the catalyst surface, inhibiting the adsorption of furan ring on the NiZn 0.1 Ce surface, thus precisely controlling hydrogenation sites at the C O rather than the C C of the furan ring. This study provides guides for precise regulation of product selectivity when designing catalysts, and it is expected to be applied to the catalytic conversion of biomass-derived platform molecules.
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Nature Catalysis
·
2025
·
IF 44.6
Ren Yue,Kong Wei,Li Yang,Zhan Wang,Zhang Chunyu,Miao Yuhang,Yao Bingxin,Li Shengnan,Li Zhenhua,Liu Xiang,Zhan Sheng,Zhou Hua,Shao Mingfei,Duan Haohong
Aqueous electrolysis offers a potential sustainable route for converting biomass derivatives to plastic monomers, such as 5-hydroxymethylfurfural oxidation to 2,5-furandicarboxylic acid (FDCA). However, selective electrosynthesis of high-concentration FDCA at kilowatt scale and ampere-level current density remains an unmet challenge, hindering commercialization. Here we show an engineered solid polymer electrolyte (SPE) reactor to steer Faradaic and non-Faradaic side reactions, achieving FDCA production at an industrially relevant current density (1.5 A cm −2 ) while maintaining high selectivity (97.0%), Faradaic efficiency (88.2%) and concentration (~1.24 M). The stability of the SPE reactor was demonstrated in continuous operation at 0.5 A cm −2 over 140 h. Moreover, a 4.3-kW electrochemical platform was constructed with a scale-out strategy, reaching a pilot-scale FDCA production rate (33 kg per day). This work shows the capability of reactor engineering to enable selective and large-scale production of sustainable chemicals via electrochemical processes.
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FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Xiangxin Wang,Qingxue Chen,Shubo Luo,Dongying Cui,Sinan Mu,Jufang Li,Qinggang Xie,Bailiang Li,Hong You
The Maillard reaction enhances flavor in thermally processed infant formula (IF) yet generates furfural derivatives such as 2-furfural and 5-hydroxymethylfurfural (5-HMF), raising safety concerns. This study assessed the toxicity of these compounds using both wild-type and transgenic zebrafish models, while establishing quantitative concentration-specific toxicity relationships. Stored IF produced elevated levels of 2-furfural and 5-HMF compared to normal IF, leading to immune, nervous, and liver toxicity in exposed zebrafish. Both compounds induced immunotoxicity at maximum non-lethal concentrations and hepatotoxicity across tested doses. Notably, 5-HMF showed minimal neurotoxicity and gastrointestinal (GI) effects, while 2-furfural induced neurotoxicity at its lowest concentration and GI toxicity at 10 % lethal concentration (LC 10 ). Moreover, high levels of these compounds in powdered IF can elicit immune, hepatic, and neurotoxicity, but not GI toxicity, with differences from pure compounds likely attributable to the influence of the complex dairy matrix. To our knowledge, this is the first study using the zebrafish model to systematically evaluate the immunotoxicity, neurotoxicity, hepatotoxicity and GI effects of 2-furfural and 5-HMF, and to establish quantitative, concentration-dependent, organ-specific toxicity relationships. These findings reveal the safety risks of these Maillard-derived compounds and highlight the need to optimize thermal processing to reduce their formation and improve infant-formula safety.
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PubMed
高影响因子
Catalysts
·
2025
·Vol. 15
·期 5
·465
·
IF 4
Zongke He,Pengfei Jiang,Qianqian Cui,Ziyue Wang,Yaozhong Wei,Chao Luo,Jichang Guo,Chang Liu,Wei Zhang
In this work, the method of highly efficient conversion ofl-rhamnose to 5-methylfurfural (MF) catalyzed by various catalysts in a biphasic system was developed. To enhance the MF yield, the effects of the catalyst species, reaction temperature (150–180 °C), extraction solvents and volume ratio of the extraction to the aqueous phase (0–5) on the conversion ofl-rhamnose to MF were systematically investigated. Under optimal conditions, a high MF yield of 94% was achieved in the biphasic “diisopropyl ether (DIPE) + H2O” system due to the fact that the extraction of MF to the DIPE phase significantly inhibits the condensation and degradation of MF in water. Finally, detailed reaction energetics and chemical structures of intermediates of thel-rhamnose dehydration to MF were investigated using the B3LYP level of theory and the SMD solvation model. It is evident that MF, which exhibits excellent chemical stability, harbors the potential to function as a bio-derived platform chemical within the domain of the green industry.
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JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
·
2025
·Vol. 29
·期 6
·e70470
·
IF 4.2
Chuchu Xu,Renjun Zhu,Qingfeng Dai,Yaoqing Li,Gengyuan Hu,Kelong Tao,Yuhong Xu,Guangen Xu,Guolin Zhang
The main reason for the failure of chemotherapy therapies based on 5-Fluorouracil (5-Fu) is the development of resistance to 5-Fu in cancer patients, particularly those with colorectal cancer. Tissue inhibitor of metalloproteinases 2 (TIMP-2) has been shown to be associated with colorectal cancer (CRC), but its correlation with 5-Fu resistance in colorectal cancer has not been thoroughly studied. We screen the expression of different cytokines through Cytokine array. CCK-8 assay was conducted to evaluate the IC 50 of 5-Fu and cell proliferation. ELISA and RT-qPCR were performed to detect TIMP-2 expression levels in cells and patient serum. Western blotting was utilised to analyse the differences in the expression of proteins related to signalling pathways in cells. Through cytokine array screening, we found that the expression of TIMP-2 was significantly increased in CRC drug-resistant cell lines. In addition, the expression of TIMP-2 in the serum of patients with CRC resistance to 5-Fu was significantly increased. Subsequent mechanistic experiments showed that TIMP-2 regulated the resistance of CRC cells to 5-Futhrough the JAK–STAT signalling pathway. Moreover, anti-TIMP-2 antibody or small molecule drug LY2784544 targeting the JAK–STAT signalling pathway can effectively reverse the resistance of CRC cells to 5-Fu. It is exactly TIMP-2 that mediates the resistance of CRC to 5-Fu through the JAK–STAT signalling pathway. Targeting drugs for TIMP-2 or the JAK–STAT signalling pathway are expected to be opportunities to reverse 5-Fu resistance in CRC.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Tianwei Wu,Zhenyu Du,Hao Wang
Reducing energy consumption in the desorption process of chemical absorption-based carbon capture is crucial for achieving efficient industrial-scale post-combustion carbon capture. Despite advancements in solvent improvement, catalyst application, and process optimization, there remains a significant gap between the energy consumption level and its theoretical limit. This study proposed an innovative surface treatment-seeding-hydrothermal synthesis method for loading ZSM-5 zeolite acidic catalysts onto the surface of industrial packing to enhance both the reaction kinetics and mass transfer during desorption, thereby reducing desorption energy consumption. The effectiveness of the loaded catalyst was verified in the temperature range of 86–106 °C, showing 7.84 %-37.25 % improvement in desorption amounts compared to commercial catalysts of equal volume. The optimal synthesis parameters for the loading process were investigated using various characterization techniques. It was observed that controlling the synthesis time and the number of layers to induce surface roughness, in conjunction with utilizing gels with a higher silica-to-alumina ratio, significantly enhanced the desorption performance of the supported catalytic packings based on the optimized parameters, supported catalytic packings prepared with industrial packings were tested in a simulated cyclic desorption tower. The results showed that, compared to the blank packing, desorption amounts increased by 24.30 %, 78.57 %, and 53.50 %, while relative energy consumption decreased by 19.66 %, 44.03 %, and 35.57 %, respectively.
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