JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2018
·
IF 3.412
Dijun Zhang,Jiaojiao Han,Yanyan Li,Bei Yuan,Jun Zhou,Lingzhi Cheong,Ye Li,Chenyang Lu,Xiurong Su
To discern whether tuna oil modulates the expression of brain proteins and the gut microbiota structure during aging induced by d-galactose, we generated an aging mouse model with d-galactose treatment, and the mice showed aging and memory deterioration symptoms according to physiological and biochemical indices. Treatment with different doses of tuna oil alleviated the symptoms; the high dose showed a better effect. Subsequently, brain proteomic analysis showed the differentially expressed proteins were involved in damaged synaptic system repairment and signal transduction system enhancement. In addition, tuna oil treatment restored the diversity of gut microbiota, 27 key operational taxonomic units, which were identified using a redundancy analysis and were significantly correlated with at least one physiological index and three proteins or genes. These findings suggest that the combination of proteomics and gut microbiota is an effective strategy to gain novel insights regarding the effect of tuna oil treatment on the microbiota–gut–brain axis.
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高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2022
·Vol. 194
·期 11
·5274-5291
·
IF 3.094
Lei Jiping,Tang Kexin,Zhang Ting,Li Yan,Gao Zhen,Jia Honghua
2-O-α-D-Glucosyl glycerol (2-αGG) can be used as a multipurpose anti-aging, cell-stimulating, and skin moisturizing agent in the cosmetic industry. Sucrose phosphorylase (SPase) has been widely used in the production of 2-αGG. In this paper, the gene encoding sucrose phosphorylase from Bifidobacterium longum (BlSP) was inserted into pRSF-Duet-1 to construct the recombinant plasmid pRSF-BlSP and was functionally expressed in E. coli BL21(DE3) to be used as a biocatalyst for the synthesis of 2-αGG firstly. The mutations of BlSP were carried out based on alanine scanning, and a positive mutant G293A with a 50% increase in activity for 2-αGG production was identified. Mutant G293A has less K m and bigger k cat / K m towards glycerol than the parental BlSP. Subsequently, the production of 177.6 g/L 2-αGG was attained from 1 M sucrose and 1.2 M glycerol catalyzed by 17 mg/mL G293A mutant. This study indicated that BlSP has good potential in the production of 2-αGG.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 46
·期 2
·592-598
·
IF 3.591
Rui Wang,Wei Zhang,Ying Tang,Ze-Hui Qi,Yuan-Hui Yu,Hong-Bo Tan,Dian-Yong Tang,Zhi-Gang Xu,Zhong-Zhu Chen
An efficient one-pot four-component reaction for the synthesis of a new family of novel bridgehead nitrogen-containing pyrido[1,2-d][1,4]diazepines has been described and its mechanism has been proposed, which follows a ring-closure and ring-cleavage pathway. The protocol involved a cyclization through γ-selective C–C bond formation, an intramolecular Michael addition and a ring-opening of a pyranone ring under refluxing conditions with high to excellent yields. The advantages of this methodology, including the use of easily available raw materials and an inexpensive catalyst, an open-air reaction setup, wide functional group tolerance, and gram-scale synthesis, make the developed methodology a practical way to access novel pyrido[1,2-d][1,4]diazepines and functionalized tricyclic or polycyclic fused 1,4-diazepines as well as novel analogs of important biologically active molecules.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2025
·
IF 3.7
Feiyu Gao,Pengyu Sun,Shiao Du,Youcai Jin,Jimin Xue,Wei Chen
Wood, as a widely available renewable resource, was extensively used in many fields. Utilizing its abundant hydroxyl groups of surface and unique hierarchical pore structure, N -methyl-D-glucosamine (NMDG), a functional monomer with unique chelation properties towards boric acid/borate, was grafted onto its surface after modification, successfully preparing the NMDG-modified wood-based functional material (Wood-NMDG). When this material was applied for boron adsorption in aqueous, research found that both solution pH and boron concentration significantly affected its adsorption performance. Studies on its adsorption kinetics, adsorption isotherms and thermodynamics revealed that the material possessed excellent adsorption capacity and rapid adsorption kinetics. After adsorption with salt lake brine, it demonstrated outstanding specificity and selectivity. Dynamic adsorption studies using simulated seawater yielded a breakthrough time of 42 hours. Based on the World Health Organization standard for boron concentration in drinking water, its capacity for treating seawater into drinking water reached 2520 L·kg –1 . However, cycling experiments indicated a certain degree of decrease in the adsorption properties of the material. Nevertheless, considering the abundant availability, low cost, and ease of modification of wood as a raw material, Wood-NMDG held broad application prospects as an efficient removal agent for seawater desalination, drinking water production and irrigation water treatment.
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DYES AND PIGMENTS
·
2016
·
IF 4.055
Jia-Xiang Cheng,Zu-Sheng Huang,Lingyun Wang,Derong Cao
Four novel D–π–A–π–A metal-free organic dyes Q1-Q4 were synthesized and the impacts of the auxiliary acceptors on the photovoltaic performances were studied. Q2 with quinoxaline as the auxiliary acceptor exhibited the best photovoltaic performance due to its highest short-circuit photocurrent density (17.22 mA cm −2 ), leading to a power conversion efficiency of 7.42% under simulated AM 1.5 G illumination. Q1 with the strongest electron withdrawing group (pyrazino[2,3- g ]quinoxaline) as the auxiliary acceptor showed the weakest performance, which can be attributed to electron trap and mismatch of energy-level. The results showed that the different electron-withdrawing property of auxiliary units significantly influenced the absorption, energy levels and photovoltaic performance. Incorporating auxiliary acceptor with moderate electron-deficient ability can extend the absorption range and adjust the molecular orbital energy levels, resulting in better photovoltaic performance.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Yingyuan Zhao,Jing Guo,Anmin Liu,Tingli Ma
2D materials and their composites are promising energy storage candidates. In this work, 2D horizontal heterostructure comprised of Ni 3 S 2 /delaminated-Ti 3 C 2 , denoted as Ni 3 S 2 /d-Ti 3 C 2 , supported on Ni foam is prepared by a two-step method and used as binder free electrode for hybrid supercapacitor . The as-obtained composites are characterized by X-ray diffraction analysis, scanning electron microscope, transmission electron microscope and X-ray photoelectron spectroscopy. The electrochemical properties of Ni 3 S 2 /d-Ti 3 C 2 on Ni foam (denoted as Ni 3 S 2 /d-Ti 3 C 2 /NF) are studied using cyclic voltammetry , galvanostatic charge-discharge analysis and electrochemical impedance spectroscopy . It is found that the Ni 3 S 2 /d-Ti 3 C 2 /NF electrode exhibits superior capacitive performance with specific capacity of 2204 F g −1 at a constant current density of 1 A g −1 . A hybrid supercapacitor is fabricated by using Ni 3 S 2 /d-Ti 3 C 2 /NF electrode as positive electrode, active carbon (AC) coated on Ni foam as negative electrode and KOH aqueous solution as electrolyte. The Ni 3 S 2 /d-Ti 3 C 2 /NF//AC hybrid supercapacitor exhibits a maximum energy density of 23.6 W h kg −1 and a maximum power density of 4004.4 W kg −1 . The results supply new strategy for constructing MXene-based 2D horizontal heterostructure, and suggest that Ni 3 S 2 /d-Ti 3 C 2 /NF composite as a binder free electrode is an ideal candidate for supercapacitor applications.
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Journal of Materials Chemistry A
·
2025
·
IF 9.5
Xiang Li,Guiyang Yu,Ruihong Sun,Ke Gong,Jinghao Zhu,Debao Wang
Directional and smooth transfer of charges across the interface is pivotal for heterojunction materials in terms of photochemical activity. However, large lattice mismatch and disordered interface inevitably exist in actual-prepared heterojunctions and bring great uncertainty in interfacial charge migration. Herein, an ingenious strategy with photoinduced metastable-charging d-orbital electrons of Re centers at the interface of ReS2/ZnIn2S4 (ReS2/ZIS) is clarified. This metastable interfacial electronic state is involved in creation of gradient charge migration channels. The charging process raises the occupancy of electron density, which provides large difference of electronic potential for the subsequent charge migration to ReS2. This gradient charge migration significantly accelerates the mobility and the electron injection rate at the interface, which achieves the 6.2-fold and 7.7-fold improvement. Consequently, the optimized 10% ReS2/ZIS composite exhibits the conversion rate for photocatalytic oxidation amine of 22.84 mmol·gcat−1 ·h−1, which is the highest efficiency achieved so far for photocatalytic amines oxidation coupling upon ReS2-based composites. This research furnishes original insights for charging orbital electrons to steer kinetics process of charge transfer and shed light on the design of advanced heterojunction materials for efficient solar energy conversion.
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iScience
·
2023
·
IF 5.8
Jiancheng Zhao,Christian Marcus Pedersen,Honghong Chang,Xianglin Hou,Yingxiong Wang,Yan Qiao
Herein, we report choline chloride-based deep eutectic solvents (DESs) promoted conversion of N -acetyl- d -glucosamine (GlcNAc) into nitrogen-containing compounds, i.e., 3-acetamido-5-(1′,2′-dihydroxyethyl) furan (Chromogen III) and 3-acetamido-5-acetylfuran (3A5AF). The binary deep eutectic solvent choline chloride-glycerin (ChCl-Gly), was found to promote the dehydration of GlcNAc to form Chromogen III, which reaches a maximum yield of 31.1%. On the other hand, the ternary deep eutectic solvent, choline chloride-glycerol-B(OH) 3 (ChCl-Gly-B(OH) 3 ), promoted the further dehydration of GlcNAc into 3A5AF with a maximum yield of 39.2%. In addition, the reaction intermediate, 2-acetamido-2,3-dideoxy- d - erythro -hex-2-enofuranose (Chromogen I), was detected by in situ nuclear magnetic resonance (NMR) techniques when promoted by ChCl-Gly-B(OH) 3 . The experimental results of the 1 H NMR chemical shift titration showed ChCl-Gly interactions with α-OH-3 and α-OH-4 of GlcNAc, which is responsible for promoting the dehydration reaction. Meanwhile, the strong interaction between Cl − and GlcNAc was demonstrated by 35 Cl NMR.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Ya-wei Lu,Li-ya Xie,Meng-han Qi,Shen Ren,Yue-qi Wang,Jun-nan Hu,Zi Wang,Shan Tang,Jing-tian Zhang,Wei Li
Objectives: The aim of this study was to investigate the ameliorative effect of platycodin D (PD) on cognitive dysfunction in type 2 diabetes mellitus (T2DM) and its potential molecular mechanisms of action in vivo and in vitro. Materials and methods: An animal model of cognitive impairment in T2DM was established using a single intraperitoneal injection of streptozotocin (100 mg/kg) after 8 weeks of feeding a high-fat diet to C57BL/6 mice. In vitro, immunofluorescence staining and Western blot were employed to analyze the effects of PD on glucose-induced neurotoxicity in mouse hippocampal neuronal cells (HT22). Results: PD (2.5 mg/kg) treatment for 4 weeks significantly suppressed the rise in fasting blood glucose in T2DM mice, improved insulin secretion deficiency, and reversed abnormalities in serum triglyceride, cholesterol, low-density lipoprotein, and high-density lipoprotein levels. Meanwhile, PD ameliorated choline dysfunction in T2DM mice and inhibited the production of oxidative stress and apoptosis-related proteins of the caspase family. Notably, PD dose-dependently prevents the loss of mitochondrial membrane potential, promotes phosphorylation of phosphatidylinositol 3 kinase and protein kinase B (Akt) in vitro, activates glycogen synthase kinase 3β (GSK3β) expression at the Ser9 site, and inhibits Tau protein hyperphosphorylation. Conclusions: These findings clearly indicated that PD could alleviate the neurological damage caused by T2DM, and the phosphorylation of Akt at Ser473 may be the key to its effect.
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高影响因子
ADVANCED MATERIALS
·
2025
·Vol. 38
·期 3
·e10760
·
IF 26.8
Jing Li,Xiaotao Zhang,Jinpeng Li,Xiaoyu Zheng,Minghui Li,Jiadong Zhou,Erhong Song,Yao Zhou
Metal-based site, as an important type of active site, plays the benchmarking role in the redox and charge transfer processes in the heterogeneous catalysis. Modulating the valence state of metal site as a promising and simple strategy theoretically enables control over the adsorption strength of reaction intermediates. However, this strategy is intrinsically limited by the local atomic configuration, often leading to unpredictable catalytic failures. Here, it is reported that the intermediate adsorption strength of platinum active site with different valence states exhibits a linear relationship with the d-band width of Pt (W d -Pt ). Adjusting the nearest-neighbor coordination environment of Pt sites by changing the transition metals bonded to Pt effectively modulates the W d -Pt , which offers a high activity (η 10 = 14 mV) in the hydrogen evolution reaction (HER). W d -Pt broadening elevates the Pt─H anti-bonding states across the Fermi level, strengthening active site-absorbate interactions and thereby tuning HER catalytic activity. In addition, this d-band width engineering strategy can be expanded to other catalysts with the metal active site. The present study transcends limitations in valence state modulation and sheds light on deeper understanding of d-band structure of metal sites and a methodology to boost the activity of metal sites in heterogeneous catalysis.
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APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Moxing Cheng,Haoyun Sheng,Yin’an Zhu,Ziqi Tian,Yichao Lin
The development of highly active and durable catalysts for the acidic oxygen evolution reaction (OER) is urgently needed to accelerate reaction kinetics and reduce energy barriers. Herein, we propose to tune the local electronic structure in RuO 2 via yttrium ion (Y 3+ ) doping to facilitate the OER process following oxide path mechanism (OPM). The electron-deficient of Y 3+ redistributes local charge density, strengthens metal–oxygen bonds to suppress lattice degradation. Moreover, the incorporation of larger Y 3+ radius reduce the Ru–Ru distance, and thereby benefits O–O coupling. The optimized Y 0.11 Ru 0.89 O 2−δ catalyst exhibits an exceptionally low overpotential of 195 mV at 10 mA cm −2 for acidic OER and operates stably for 250 h at 100 mA cm −2 in a PEM electrolyzer. Theoretical investigations reveal that Y–O–Ru structure effectively modifies the chemical environment and optimizes the atomic configuration of active sites. This study establishes electron-deficient, large-radius dopants as an effective strategy for designing efficient and durable acidic OER catalysts, enhancing RuO 2 performance.
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Nano-Micro Letters
·
2013
·Vol. 5
·期 3
·182-190
·
IF 2.057
Zhu Wen,Wu Yuanyuan,Wang Chengyin,Zhang Ming,Dong Guanxiu
The highly ordered silver-coated colloidal crystals arrays and macroporous silver films were derived through an electrostatics-induced adsorption effect using polystyrene (PS) as templates. Carboxyl-modified PS microspheres were prepared by emulsifier-free emulsion polymerization using methacrylic acid (MAA) as the functional monomer. PS microspheres were self-assembled into close packing colloidal crystals of facecentered cubic arrays to the substrate with vertical deposition method. These colloidal crystals were modified using dopamine (DA) to form poly-dopamine (PDA) during its oxidative polymerization. Through electrostatic interaction, the silver nanoparticles were deposited and adsorbed onto the surfaces of colloidal crystals templates by exposing [Ag(NH 3 ) 2 ] + solution to infrared irradiation. Removal of the polymeric template by etching with methylbenzene solvent resulted in 3D ordered macroporous silver films. The structural and properties of the ordered silver-coated arrays and macroporous silver films were characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), UV-vis spectroscopy and surface-enhanced Raman spectroscopy (SERS). The results indicate that the prepared silver-coated arrays and macroporous silver films possess the features of ordered multilayer arrangement, uniformity and repeatability as well as an ideal SERS effect.
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