JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Guilin Zhou,Xiaodong Zhang,Xin-Long Ni
A water-soluble terpyridine-based cationic fluorescent probe ( SP - TPy ) was synthesized, which emerged with pH-dependent amphiphilicity, resulting in self-assembly and disassembly in aqueous media with the aggregation-induced emission (AIE) property. In neutral water (pH 7.4), a moderate sensing response to Hg 2+ ions was given by the self-assembly of SP - TPy . However, in acidic aqueous media, the monomer of SP - TPy not only appeared to be highly selective and sensitive for Hg 2+ ions, but also displayed highly efficient removal of Hg 2+ ions from solution by rapid precipitation, which was attributed to the coordination-triggered reassembly of SP - TPy . The removal efficiency of SP-TPy f or Hg 2+ was found to be over 99%. Further study indicated that the precipitates were composed of various polyhedral porous frameworks, a property that was further used to adsorb H 2 S gas to form HgS complexes with higher uptake capacities. In addition, SP - TPy can be efficiently regenerated and recycled using a simple treatment with acidic water after adsorption of the H 2 S gas.
✓ 已验证
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2018
·
IF 4.805
Chao Zhang,Yugang Song,Zhihui Sang,Lingpeng Zhan,Yu Rao
A strategy combining O- and N-containing directing groups has been developed for the synthesis of 2,2′-biaryl via Pd-mediated C–H bond activation and oxidative coupling. This new transformation may proceed through a mechanism involving Pd(II) and Pd(IV) intermediates. We found the use of PTSA and HFIP to be critical for the reaction and suggest that these reagents could serve as efficient ligands for this C–C bond formation. This methodology provides broad functional group tolerance, excellent reactivity, and high yields.
✓ 已验证
DOI
高影响因子
Molecular Catalysis
·
2023
·
IF 4.6
Xiangquan Qin,Yiping Jiang,Jie Chen,Fuquan Yao,Longyi Jin,Zhiqi Cong
Selective hydroxylation of C( sp 3 )–H bonds is a long-standing challenge in the organic synthesis field. We herein report an artificial P450 peroxygenase system facilitated by ω-pyridyl fatty acyl amino acids that can hydroxylate broad-spectrum alkanes, including linear and cyclic alkanes and benzylic and allylic alkane chains. Compared with the previously reported dual-functional small molecule (DFSM) with imidazole as a catalytic group (Im-DFSM), pyridyl DFSM (Pyd-DFSM) produced substantially higher total turnover numbers (TTNs) for the hydroxylation of medium-chain alkanes and cycloalkanes (C6–C8), e.g., 12.0-fold and 17.1-fold increased TTNs of P450 mutant F87A/T268V for heptane and cycloheptane , respectively. In addition, Pyd-DFSM altered the enantioselectivity of benzylic hydroxylation, e.g., it almost inverted the configuration observed in the benzylic hydroxylation of ethylbenzene and tetralin . More importantly, Pyd-DFSM showed excellent regioselectivity for allylic hydroxylation over epoxidation of terminal alkenes and cycloalkenes , e.g., up to 94% allylic hydroxylation of 1-hexene was observed. This work significantly enhances the catalytic toolbox of the DFSM-facilitated P450 peroxygenase system; it not only substantially expands the chemical space of P450 enzymes, but also provides an alternative solution for the selective hydroxylation of C( sp 3 )–H bonds.
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2018
·
IF 3.141
Wei Bi,Yanjie Hu,Wenge Li,Hao Jiang,Chunzhong Li
In this work, a nanoreactor combining layers of facile traditional two-dimensional (2D) material, hexagonal boron nitride (h-BN, which often called the white graphene) with Pt/Al2O3 catalyst was designed to exhibit higher stability, activity, and selectivity in automobile exhaust treatment. Characterization revealed that h-BN does coat on the surface of platinum and forms a distinct Pt@h-BN/Al2O3 core–shell nanostructure. This as-prepared catalyst possesses good thermal stability and selectivity, because of the excellent high-temperature tolerance and the multidefected structure of the h-BN shell; that is, small molecules such as CO and O2 can easily intercalate into the nanoreactor, while large molecules such as propylene are blocked out. Meanwhile, the intercalated reactants can achieve the conversion of CO to CO2 faster (ΔT100 = 20 °C) with the confinement effect. The study indicates that constructing a nanoscale confined environment with two-dimensional (2D) coating can enhance the performance of the catalyst in multiple aspects and simultaneously provide a good example for designing nanostructured catalysts with multifaceted improvement.
✓ 已验证
DOI
高影响因子
MATERIALS & DESIGN
·
2025
·
IF 7.9
Yuannong Qu,Ji Zou,Weimin Wang,Wei Ji,Zhengyi Fu
The h-BN/ZrO 2 composites for preparing ceramic side sealing plate were obtained with spark plasma sintering (SPS) at 1700 °C for 10 min in the study. By varying AlN content from 0 to 20 wt%, we systematically explored its influence on sintering behavior, microstructure evolution, mechanical performance, and corrosion mechanism at1600 °C. Results show that the rapid heating and uniaxial pressure during SPS and the in-situ reactions between AlN and ZrO 2 promoted the densification of composites. The main reaction products were ZrN, which acted as an effective oxygen scavenger, consuming dissolved oxygen ([O]) and converting into ZrO 2 . These newly formed ZrO 2 particles filled residual porosity within the matrix and nucleated around pre-existing ZrO 2 grains, progressively coalescing into continuous Zr-rich barrier layer.Thereby preventing molten steel from further penetrating into the matrix. The corrosion depth of the composite with 5 wt% AlN content in molten steel at 1600 °C after 2 h was only 69 μm. Meanwhile, it showed a thermal conductivity of 25 W m −1 K −1 and a coefficient of thermal expansion of 3.7 × 10 -6 K −1 , demonstrating excellent thermal shock resistance. The composites are expected to be used to manufacture side sealing plates for the novel continuous casting of thin strip.
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2021
·Vol. 17
·期 52
·2105643
·
IF 13.281
Bo Liu,Linjuan Zhang,Yuanyuan Luo,Lei Gao,Guotao Duan
The supported metal catalysts on scaffolds usually reveal multiple active sites, resulting in the occurrence of side reaction and being detrimental to the achievement of highly consistent catalysis. Single atom catalysts (SACs), possessed with highly consistent single active sites, have great potentials for overcoming such issues. Herein, the authors used SACs to modulate kinetic process of gas sensitive reaction. The supported Pd SACs, established by a metal organic frameworks-templated approach, promoted greatly the detection capacity to hydrogen sulfide (H 2 S) gas with a very high sensitivity and selectivity. Density functional theory calculations show that the supported Pd SACs not only increased the number of electrons transferring from H 2 S molecules to Pd SACs, but strengthened surface affinity to H 2 S. Moreover, the H S bonds of H 2 S molecules absorbed on Pd atomic sites are more likely to be dehydrogenated directly into sulfur species. Significantly, quasi in situ XPS analysis confirmed the presence of sulfur species during H 2 S detection process, which may be a major cause for such detection signal. Based on these results, a suitable sensing principle for H 2 S gas driven by Pd SACs was put forward. This work will enrich catalytic electronics in chemiresistive gas sensing.
✓ 已验证
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2019
·
IF 14.229
Ge Shu,Yuda Li,Zhuang Wang,Jia-Xing Jiang,Feng Wang
Conjugated polymers have recently emerged as encouraging metal-free photocatalysts for solar energy conversion under visible light irradiation. Unfortunately, photocatalytic activities of the current polymers are still inadequate. Herein, we present a simple but quite attractive conjugated homopolymer (PDBTSO) based a dibenzothiophene-S,S-dioxide moiety. The introduction of sulphonyl group to a polyfluorene-like backbone can cause richly available active sites and lead to the efficient separation of photoexcited charge carriers, thus yielding impressive photocatalytic performance. Furthermore, we explored a natural “phosphorylation” strategy for increasing photocatalytic hydrogen production over PDBTSO. Remarkably, an extremely high hydrogen evolution rate of 44.2 mmol h −1 g −1 was achieved with the optimum addition of K 2 HPO 4 under visible light irradiation.
✓ 已验证
DOI
高影响因子
POLYMER SCIENCE SERIES B
·
2015
·Vol. 57
·期 5
·460-472
·
IF 0.577
Sa Zongpeng,Li Yapeng,Zhao Haochen,Hu Qi,Wei Jia,Wang Jingyuan
Through H-shaped macroinitiator glycol-chlorine((Cl) 2 -PEG-(Cl) 2 ) to initiate the ATRP reaction of 2-Hydroxyethyl Methacrylate (HEMA) we synthesized H-shaped copolymer (PHEMA) 2 - b -PEG- b -(PHEMA) 2 . After we modified the copolymer with histidine (His), the self-assembling and drug release behavior was studied. The morphology of the copolymer micelles and drug loaded micelles were examined by transmission electron microscope (TEM). Spherical micelles and core-shell structure with a diameter of 165 nm were obtained (at pH = 7.0). Due to the presence of imidazole-ring in histidine the copolymer show commendable pH-sensitivity, which made the copolymer potential application as drug carrier exhibiting good control-released property.
✓ 已验证
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2025
·
IF 3.6
Jingru Zou,Lingmeng Xie,Wen Qin,Xingang Xie,Xing Huo
The Groebke–Blackburn–Bienaymé (GBB) reaction provides efficient access to imidazole-fused heterocycles, yet it is inevitably endowed with an isocyanide-derived secondary amino group in products. Herein, we report a Pd(II)-catalyzed sp2 C–H carbonylative amidation strategy using Co2(CO)8 as a safe CO surrogate. Leveraging the native aryl amino group as a directing motif, this protocol enables direct conversion of GBB adducts into pharmaceutically relevant imidazo[1,2-a]pyridine-fused δ-lactams with up to 86% yield. The method demonstrates exceptional functional group tolerance and eliminates prefunctionalization requirements, offering a streamlined approach to access complex nitrogen-rich architectures.
✓ 已验证
DOI
PubMed
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2024
·
IF 4.1
Luo Fang-Hua,Dong Zhi-Tao,Chen Guo-Hua,Ma Chen,Wang Huai-Yuan
Janus films with asymmetric physical/chemical properties have attracted considerable attention due to their promising applications in personal thermal management, electronic skins, sensors, actuators, etc. However, traditional methods for fabricating Janus films conventionally need the assistance of an interface or auxiliary equipment, which are usually complex and time-consuming. Herein, flexible poly(vinyl alcohol) (PVA)/graphene oxide (GO)/h-BN (recorded as PVA/GO/h-BN) Janus films with thermally, optically, and electrically anisotropic properties are fabricated by a simple density deposition self-assembly method, which just utilizes the density difference between GO and h-BN during water evaporation. Experimental results show that the two sides of the acquired Janus films have obvious asymmetric characteristics. In the original state of the PVA/GO/h-BN Janus films, the thermal conductivity of the GO side (10.06 W·m −1 ·K −1 ) is generally lower than that of the h-BN side (10.48 W·m −1 ·K −1 ). But after GO is reduced, the thermal conductivity of the rGO side reaches 12.17 W·m −1 ·K −1 , surpassing that of the h-BN side. In addition, the relative reflectance of the h-BN side of Janus film is also significantly higher than that of the rGO side, and the surface resistance difference between the two sides is about 4 orders of magnitude. The prepared PVA/GO/h-BN Janus films show great application potential in human thermal management, light conversion switches, and electronic skins. This study provides a simple and versatile strategy for fabricating Janus films with multifunctional (such as thermal, optical, and electrical) anisotropies.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Yipeng Zhang,Shijia Wu,Yisheng Chen
A portable biosensor for the peanut allergen Ara h 1 was developed by integrating a polydopamine-functionalized pipette tip, CRISPR/Cas12a signal amplification, and a personal glucose meter. Ara h 1 binding induced partial displacement of a cDNA activator, which activated Cas12a trans-cleavage and released glucose oxidase from GOx–DNA conjugates. The released enzyme catalyzed glucose oxidation, producing a quantitative decrease in glucose concentration. Under optimized conditions, the assay showed a linear range of 50–1000 ng/mL and a solution-based limit of detection of 22.19 ng/mL. Post-extraction matrix-spike tests in commercial peanut-biscuit and peanut-beverage extracts yielded recoveries of 101.58–104.68% with relative standard deviations below 3.44%. These results demonstrate the analytical feasibility and preliminary matrix compatibility of the platform, although validation using pre-extraction fortified, incurred, and naturally contaminated foods is still required.
✓ 已验证
产品关联
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2026
·
IF 3.6
He-Mei Yin,Xin-Yu Sun,Ping Xu,Shu-Long Liu,Fu-Min Xue
Baloxavir marboxil (BXM), a novel oral antiviral drug, is classified as BCS II and suffers from bioavailability limitations due to its low solubility. To overcome these limitations, a cocrystallization strategy was adopted in the present study. It is noteworthy that no cocrystal form of BXM has been reported in the CSD database. This study reports the synthesis and comprehensive characterization of a novel baloxavir marboxil and probenecid (PRO) pharmaceutical cocrystal (BXM-PRO), which was designed to improve the dissolution performance of BXM for enhanced therapeutic efficacy. The single crystal was successfully prepared via slow evaporation from a mixed solvent of methanol and water and thoroughly characterized using single-crystal X-ray diffraction, powder X-ray diffraction, thermogravimetric and differential scanning calorimetry, Fourier transform infrared spectra, scanning electron microscopy, Hirshfeld surface analysis, and density functional theory calculations. Structural analysis confirmed the formation of a cocrystal stabilized by strong O–H···O hydrogen bonds. Subsequent evaluations included the powder dissolution rate, accelerated stability, and antiviral activity. The dissolution profiles revealed that the BXM-PRO cocrystal exhibits a significantly enhanced dissolution rate and higher solubility in both water and pH 6.8 buffer compared to pure BXM. Theoretical analysis suggests that strong hydrogen bonding between hydrogens of the O–H···O complexes plays a critical role in facilitating the improved dissolution performance of the cocrystal. Additionally, cytotoxicity assessment via CCK-8 assay indicated that the cocrystal possesses lower cytotoxicity against MDCK cells than BXM. The antiviral activity of the BXM-PRO cocrystals was compared with that of BXM alone as well as with that of physical mixtures of BXM with PRO in adequate stoichiometric ratios. Antiviral assays demonstrated that the cocrystal exhibits superior efficacy against the Yamagata strain, reduced effectiveness against H1N1 PR8 and H3N2 strains, and comparable activity against the Victoria strain relative to BXM alone. These findings indicate that the BXM-PRO cocrystal represents a promising strategy to enhance the solubility and bioavailability of BXM, with potential clinical benefits for the treatment of influenza virus infections.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）