JOURNAL OF CHROMATOGRAPHY A
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2018
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IF 3.716
Yanlong Chen,Wenfen Zhang,Yanhao Zhang,Zhifen Deng,Wenjie Zhao,Huifang Du,Xue Ma,Dan Yin,Fuwei Xie,Yu Chen,Shusheng Zhang
This study reports a novel strategy for the preparation of porous aromatic framework (PAF-6) coated magnetic nanoparticles (PAF-6 MNPs) using cyanuric chloride as a planar trigonal basis upon which to build a linear piperazine linker unit. The PAF-6 MNPs were examined as an efficient solid-phase extraction (SPE) sorbent for enrichment of trace organic pollutants including phenol, 2,4,6-trinitrophenol, naphthalene, naphthol, bisphenol A, 2,4-dichlorophenol and 3-nitrochlorobenzene in water. The high-performance liquid chromatography detection limits of such analytes were in the range of 0.08–5.02 ng/mL and recoveries were found to be 84.0–94.0% in well water, tap water, river water and wastewater. The main toxic components of cigarette smoke, including phenolic compounds and benzo[a]pyrene, are efficiently adsorbed by PAF-6 MNPs, and over 50% of such toxins are removed. Theoretical computations were performed to understand the molecular interaction mechanism between PAF-6 and such analytes. The results demonstrate that the PAF-6 MNPs sorbents show excellent adsorption of phenols, polycyclic aromatic hydrocarbons and nitroaromatics based on multiple π-π stacking and hydrogen-bond interactions. These results suggest that the PAF-6 MNPs can be applied to extraction, removal and determination of diverse trace multi-target analytes from complex media.
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PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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2018
·Vol. 20
·期 18
·12808-12816
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IF 3.906
Zhiyong Li,Xiaoqing Yuan,Ying Feng,Yongkui Chen,Yuling Zhao,Huiyong Wang,Qingli Xu,Jianji Wang
Photo-induced conductivity modulation of stimuli-responsive materials is of great importance from the viewpoint of fundamental research and technology. In this work, 5 new kinds of azobenzene-based photo-responsive ionic liquids were synthesized and characterized, and UV/vis light modulation of their conductivity was investigated in an aqueous solution. The factors affecting the conductivity modulation of the photo-responsive fluids, such as photo-isomerization efficiency, photo-regulation aggregation, concentration and chemical structure of the ionic liquids, were examined systematically. It was found that the conductivity of the ionic liquids in water exhibited a significant increase upon UV light irradiation and the ionic liquids with a shorter alkyl spacer in the cation showed a more remarkable photo-induced conductivity enhancement with a maximum increase of 150%. In addition, the solution conductivity was restored (or very close) to the initial value upon an alternative irradiation with visible light. Thus, the solution conductivity can be modulated using alternative irradiation with UV and visible light. Although the reversible photo-isomerization of the azobenzene group under UV/vis irradiation is the origin of the conductivity modulation, the photo-regulated aggregation of the ionic liquid in water is indispensable for the maximum degree of conductivity modulation because UV irradiation can weaken, even break the aggregated cis-isomers of the ionic liquids in an aqueous solution.
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TALANTA
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2019
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IF 4.916
Jie Ma,Lei Bian,Lei Zhao,Xiaotong Feng,Lizhi Zhao,Zhaoyan Wang,Qiaosheng Pu
Low-cost and nontoxic fluorescent reagents are important for on-site analysis performed by non-professionals. In this work, a cheap and widely available food additive , caramel was used as an effective fluorescence reagent for the sensitive detection of 2,4,6-trinitrophenol (TNP), 2,4-dinitrophenol (DNP) and 4-nitrophenol (4-NP). Through a simple dialysis, fluorescent components of a commercial caramel were harvested with a yield as high as 60%. The structural characterization demonstrated that the fluorescent components were dehydrated oligomers of carbohydrates. Their fluorescence can be quenched by these nitrophenols . The quenching mechanism was speculated as inner filter effect. At pH 8, a linear range of 0.2–22 μM and a detection limit of 90 nM could be achieved for TNP. Based on the difference of their quenching efficiency at different pHs, TNP, DNP and 4-NP can be simultaneously determined by solving the linear equations obtained at pH 3, 5 and 8. Successful detection of these nitrophenols in the water and soil samples was performed with relative standard deviations of 1.1–5.9% and recoveries of 95–108% of spiked standards.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2019
·
IF 3.973
Jun Zhao,Chun-Liu Yu,Wei Fang,Ji-Duan Lin,Guo Chen,Xiao-Qin Wang
Self-assembled polypseudorotaxanes (PPRXs) fabricated with α -cyclodextrin and poly(ethylene glycol) (PEG) or its thiolated derivatives were candidate functional materials for enzyme soft-immobilization, encapsulation and controlled-release. The study of their interaction with Jack bean urease (JBU) indicated that they inconspicuously influenced the activity and stability of JBU during long storage, up to 30 days. The macro-species were inaccessible to JBU’s active site and the steric effect might play a significant role in the stabilization of JBU, when compared with the small-molecular sulfhydryl inhibitor thioglycolic acid. Circular dichroism and fluorescence spectra analyses revealed that thiolated PEG 400 -(SH) 2 and its assembly PPRX 400 (SH) brought in perturbations to certain α -helical or β -sheet domains of JBU, making JBU’s conformation more flexible. The resulting partial unfolding of domains exposed several hydrophobic clusters and varied JBU’s surface hydrophobicity. It also rendered the chromophores more hydrophilic and more bared to the polar environment, leading to the typical bathochromic-shift and quenching in intrinsic and synchronous fluorescence spectra. Moreover, the surface hydrophobicity profile of JBU was depicted by fluorescent probe monitoring and the unique “hydrophobic cave” motif was proposed by analyzing JBU’s structural data from the Protein Data Bank. It should be pointed out that conformational variations mainly occurred at the surface region of JBU, while the buried active bi-nickel center was not markedly influenced by the macro-species. The results demonstrated that the PPRXs might act as a proper carrier for JBU encapsulation or soft-immobilization.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2018
·
IF 2.196
Beihan Wang,Fangxian Li,Pengfei Yang,Yerong Yang,Jie Hu,Jiangxiong Wei,Qijun Yu
Carbon nanotubes (CNTs) were synthesized on a Ni catalyst–diatomite substrate using a chemical vapor deposition (CVD) method. By controlling the synthesis conditions, we explored the influence of synthesis time and temperature on the synthesis of CNTs. The carbon yield and microstructure of the resulting CNTs were investigated by thermogravity (TG), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy analysis. Then, two kinds of purification methods, annealing and acid treatment, were used on the synthesis products, diatomite–CNT, and can effectively increase the specific surface area of the product. The adsorption behaviors of diatomite–CNT composite adsorbents for phenolic compounds have been investigated. The adsorption experiments showed that the adsorption process reached equilibrium quickly, while the adsorption kinetics followed the pseudo-second-order model and the adsorption isotherm followed the Langmuir model well, respectively. The thermodynamics parameters indicated that the adsorption behavior is an exothermic process performing spontaneously. The diatomite–CNT adsorbent will perform well for removal of phenolic compounds from wastewater.
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Journal of Materials Chemistry B
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2018
·Vol. 7
·期 6
·974-985
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IF 4.776
Abid Hussain,Shengrong Guo
To prevent premature drug release from nanoparticles, it is vital to design and prepare controlled and site-specific drug release systems. We investigated a new controllable drug release mesoporous carbon nanoparticle (MCN)-based nano-system with the advantages of enhanced permeability and retention effect (EPR) to target tumors followed by the NIR-induced heat-triggered release of a chemotherapeutic drug to show anti-tumor effects. The pores of MCN with photo-thermal effects were filled with the chemotherapeutic agent doxorubicin (DOX) and the phase change material (PCM) 1-tetradecanol was used as a gatekeeper to trap DOX inside the pores of the mesoporous carbon nanoparticles and the release of DOX inside tumor cells was triggered using NIR irradiation. The surface of MCN was coated with natural sophorolipid (SLPD) to obtain nanoparticles (DOX-PCM@MCN-SLPD) with good biocompatibility, dispersibility and stability in aqueous solutions. The MCN-based nano-system had the ability to load 24% DOX trapped with the PCM before coating with SLPD. It was observed that the release of DOX was temperature-dependent above the melting point of PCM. Once DOXPCM@MCN-SLPD was delivered into MCF-7/ADR cells, the release of DOX was triggered by MCN-borne photo-thermal effects under NIR irradiation. The amount of DOX inside the tumor was visualized via confocal laser scanning microscopy, which showed a higher amount of DOX at a higher temperature compared to that at normal body temperature, further confirming the minimization of premature drug release at 37 °C.
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NEW JOURNAL OF CHEMISTRY
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2018
·Vol. 42
·期 14
·11396-11403
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IF 3.201
Lilong Gao,Wenlin Wang,Bing Yu,Hailin Cong
Responsive polymers have significant importance and promising applications in the field of biomedicine. In this study, benzimidazole (BI)-based polyesters were synthesized for the first time via amine-ene click polycondensation. Benzimidazolethione (BITO) and aliphatic diacrylates (DA) were selected as clickable monomers using the organic catalyst 4-dimethylaminopyridine (DMAP) to obtain benzimidazole-based polyesters. 1,4-Butylene diacrylate (BDA) and poly(ethylene glycol) diacrylate (PEGDA) were used as model DA to synthesize lipophilic and hydrophilic polymers, respectively. Furthermore, click polymerization of BITO with BDA and PEGDA was conducted for tricomponent polycondensation. 1H NMR, FTIR and GPC spectra demonstrated that the BITO-based polyesters were successfully synthesized via the click condensation of amine-ene. The obtained polymers exhibited pH, reactive oxygen species (ROS) and β-cyclodextrin (β-CD) triple responsiveness and the amphiphilic BITO polyester can self-assemble into nanoparticles. We believe that these novel BITO polyesters have great potential as drug delivery systems for controlled drug release in nanomedicine.
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JOURNAL OF CEREAL SCIENCE
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2018
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IF 2.302
Kuijie Gong,Lirong Chen,Xiaoyue Li,Linlin Sun,Kaichang Liu
A combination of germination and extrusion was applied to whole grain corn to increase its nutritional composition, functional properties and non-anthocyanin polyphenol profile, especially related to in vitro hypoglycemic effects. Individual germination and extrusion both led to an increase in soluble dietary fiber and lysine, methionine , tryptophan content, while insoluble dietary fiber content decreased. Extruded germinated whole corn flour (EGWCF) had a higher water absorption and solubility index, showing 103 and 575% increases over untreated ones, respectively. Germination increased free, bound phenolic acid and bound flavonoid content to 169, 230 and 311%, respectively. The total phenolic acid and flavonoid content of EGWCF was 260 and 249% of WCF, respectively. Germination increased the polyphenol composition from 12 to 15 species. Phenolic profiles of EGWCF exhibited collective effects, showing three new phenolic compounds . Polyphenol extracts showed more potent activity against α -glucosidase rather than α -amylase. Free form polyphenols had stronger inhibitory activity than the bound forms. Compared with WCF, free and bound polyphenol extracts from EGWCF increased the anti- α -glucosidase activity by 221 and 40%, and increased the anti- α -amylase activity by 105 and 108%.
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APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Yuxue Zhou,Pengfei Lv,Wei Zhang,Xiangdong Meng,Hui He,Xianghua Zeng,Xiaoshuang Shen
Pristine Bi 2 WO 6 hollow microspheres have been fabricated in ethylene glycol-water system with CTAB as crystal growth director for the first time, hybrid Au- Bi 2 WO 6 hollow microspheres was also obtained by in situ decoration of Au nanoparticles, the formation mechanisms were explored. Their photocatalytic activities on photo-reduction of Cr(VI) and photo-degradation of phenol in aqueous solution were investigated under visible light irradiation. Hybrid Au- Bi 2 WO 6 hollow microspheres displayed the highest photocatalytic activity, exhibiting a nearly complete reduction of Cr(VI) to Cr(III) within only 20 min. The excellent photocatalytic activities of heterogeneous Au-Bi 2 WO 6 hollow microspheres can be induced by the increased light harvesting efficiency (due to light multi-scattering effect of hollow architecture), high separation of photogenerated electron-hole pairs caused by electron trapping effect and surface plasmon resonance (SPR) effect of Au nanoparticles.
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JOURNAL OF POROUS MATERIALS
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2018
·Vol. 26
·期 3
·819-828
·
IF 1.858
Tao Jianli,Liu Lujuan,Zhu Peihong,Zhai Kang,Ma Qian,Zhang Danning,Ma Jie,Zhai Yunpu,Liu Yonggang,Zhang Ruiqin
A Ni-based cage-like C–SiO 2 –Al 2 O 3 (Ni/CL-CSA) catalyst was synthesized successfully via a facile dual-templating method and used for the hydrotreatment of phenol. The catalyst was characterized by SEM, TEM, XRD, TG and N 2 adsorption techniques. Results show that Ni/CL-CSA has three-dimensional connected macroporous structure with pore size of about 100 nm and ordered mesoporous windows with average pore size of approximately 3.8 nm. Size of nickel particle is 6.1 nm. BET surface area of the catalyst is 212 m 2 /g and pore volume is 0.24 cm 3 /g. Hydrogenation and the stability performance of the catalyst was studied for bio-oil model compound phenol. Results reveal that adding macropores into Ni-based mesoporous C–SiO 2 –Al 2 O 3 (Ni/MP-CSA) can improve the mass transfer rate and reduce the particles growth, thus improve the catalytic activities in the hydrotreatment of phenol, reducing catalyst sintering at high temperature and improving the stability of the catalyst.
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CHEMICAL ENGINEERING JOURNAL
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2018
·
IF 6.735
Ying Liu,Xiaoyan Chen,Yulin Yang,Yong Feng,Deli Wu,Shun Mao
Cobalt-based nanostructures have shown a great potential for radical production by activating persulfate (PS). Here, we report a facile strategy to synthesize nitrogen-doped porous Co@C nanoboxes (Co@NC) by pyrolysis of zeolitic imidazolate frameworks (ZIF-67), followed by partially etching away the metallic cobalt. With a nitrogen-enriched hollow porous carbon nanobox and embedded Co nanoparticles, the Co@NC shows high efficiency in PS activation for p-Chloroaniline (PCA) removal. The degradation study shows that a complete removal of high concentration PCA is done within two minutes, which is superior to most of the reported PCA removals with PS-based advanced oxidation processes (AOPs). More importantly, the Co@NC exhibits high catalytic activities in a wide range of pH from 5 to 9. The Co@NC also shows very limited Co 2+ release with a dissolution proportion of 0.28%, much lower than previously reported Co-based catalysts, and remains high efficiency after five successive reaction cycles. A heterogeneous activation mechanism though surface reaction is proposed, in which PCA firstly absorbs on the carbon nanobox surface, then being oxidized by generated radicals and non-radical species. The unique structure and outstanding performance of Co@NC catalysts present new insights in catalyst design for PS-based advanced oxidation for organic pollutants removal in waste water.
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ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Mengmeng Xu,Hui Zhou,Yanan Liu,Jing Sun,Wenjie Xie,Ping Zhao,Jie Liu
Alzheimer’s disease (AD) has become one of the most serious societal problems globally, with no effective treatments. Parenchymal accumulation of amyloid beta (Aβ) plaques and the formation of neurofibrillary tangles are the hallmarks of AD. Their possible interactions and synergistic effects in AD have been gradually elucidated. The failure of many clinical trials suggests that it is difficult to treat AD with a focus on a single target. Instead, multiple targets may be an important direction for AD drug research. In this study, we used protoporphyrin IX (PX)-modified oxidized mesoporous carbon nanospheres (OMCN) (PX@OMCN@PEG(OP)@RVGs) as a novel AD multifunctional nanodrug having multiple targets. The nanodrug efficiently inhibits tau phosphorylation. In addition, the use of PX with focused ultrasound triggered the production of reactive oxygen species that significantly inhibited Aβ aggregation. Both approaches notably increased the cognitive level of APP/PS1 transgenic (Tg) mice and ultimately achieved dual-target inhibition of AD. Furthermore, the safe and effective delivery of PX across the blood–brain barrier (BBB) due to modification of the RVG peptide was demonstrated in vivo and in vitro. The favorable photothermal effect of the nanoparticles improved the BBB permeability of PX@OP@RVGs under near-infrared irradiation. The results demonstrated that the novel PX@OP@RVG multifunctional nanomedicine has a dual-target treatment capability for AD and can traverse the BBB, indicating the potential for the effective treatment of AD.
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