Scientific Reports
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2024
·Vol. 14
·期 1
·1-12
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IF 3.8
Wang Yulong,Yang Songsong,Cai Heqing,Hu Hailong,Hu Kun,Sun Zhicheng,Liu Ruping,Wei Yen,Han Lu
Gelatin was widely used as scaffold materials in 3D bio-printing due to its excellent bioactivity and availability and especially that their arginine–glycine–aspartic acid (RGD) sequences could efficiently promote cell adhesion and proliferation. In this study, an electroactive and 3D bio-printable hydrogel was prepared through a two-step chemical cross-linking process. Specifically, residual free amino groups of methacrylated gelatin (GelMA) were cross-linked with the aldehyde groups of dibenzaldehyde-terminated telechelic polyethylene glycol (DF-PEG) via Schiff base bonds, forming a gel at 37 °C. During the subsequent 3D bio-printing process, GelMA underwent UV curing, forming a secondary cross-linked network to the mechanical strength and stability of the printed structure. The uniform dispersion of carbon nanotubes (CNTs) in the GelMA/DF-PEG composite hydrogel significantly increased its conductivity. The optimized GelMA/DF-PEG composite hydrogel, i.e., 30% GelMA and 25% DF-PEG (G30D25-CNTs), exhibited superior bio-printability. When the content of CNTs was above 4%, the conductivity of G30D25-CNTs hydrogel exceeded 10 –2 S/m, which satisfied the needs of cells for micro-current stimulation. Furthermore, the pore microstructures, swelling behavior, degradation ability and cell toxicity of G30D25-CNTs electroactive hydrogels were thoroughly evaluated. Thus, the G30D25-CNTs hydrogel with 4% MWCNTs could be considered for further application in electrical stimulation of tissue regeneration such as muscle and cardiac nerve tissue repair.
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高影响因子
Particuology
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2023
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IF 3.5
Yujin Zhang,Chunyan Shi,Jing Tang,Li Liu,Dongxia Yan,Qing Zhou,Xingmei Lu,Songyan Jia
Dissolution and nucleation are two essential processes for industrial crystallization. This paper investigates the effect of ethylene glycol addition on the crystallization behavior of dimethyl terephthalate (DMT) in solution. The DMT solubility in mixed solvent system (methanol-ethylene glycol) was determined by isothermal satiation approach, and the solubility was associated using seven models. The model fitting results were consistent with the experimental values. Based on the results, the metastable zone width (MSZW) of DMT was detected by the polythermal approach; the modified Sangwal's theory was used to investigate the nucleation behavior, which can provide a new way of thought for better analysis of the crystallization behavior. The results demonstrated that MSZW was associated with various elements, such as cooling rate, saturation temperature and mass fraction of ethylene glycol. The addition of ethylene glycol slowed down the nucleation rate as shown by the broadening of MSZW. We derive the solid-liquid interface energy, the nucleation driving force, the critical nucleation size and the critical Gibbs free energy according to the classical nucleation theory. It is demonstrated that the nucleation driving force and the solid-liquid interface energy are dependent and jointly influence the MSZW.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2023
·
IF 4.2
Xingyilong Zhang,Houfang Lu,Man Zhang,Hui Han,Rubo Tian,Kejing Wu,Yingying Liu,Yingming Zhu,Bin Liang
Low-temperature production of 5-hydroxymethylfurfural (HMF) from fructose in ternary deep eutectic solvents (TerDESs) of choline chloride (ChCl), ethylene glycol (EG), and maleic acid (MalA) is proposed. A fructose conversion of 99.9% and an HMF yield of 87.3% are achieved in TerDES with ChCl/EG/MalA = 3:1:1 at 70 °C in 30 min. The ChCl can effectively activate the hydroxy groups of fructose by lengthening the C–O bonds. The EG can both improve the formation of ChCl–MalA DES with wide ranges of component ratios and reduce the viscosity of the DES. A reaction mechanism considering the synergistic effect of the components in TerDES is suggested to explain the enhanced dehydration of fructose under mild conditions. The recycling results of the TerDES show stable yields of HMF within five recycle runs. This work offers an efficient solution to a green and sustainable process for a high yield of HMF production.
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ACS Biomaterials Science & Engineering
·
2023
·
IF 5.8
Shuang Li,Dongyang Niu,Tuhe Shi,Wentao Yun,Shifeng Yan,Guohua Xu,Jingbo Yin
Injectable hydrogels have drawn much attention in the field of tissue engineering because of advantages such as simple operation, strong plasticity, and good biocompatibility and biodegradability. Herein, we propose the novel design of injectable hydrogels via a Schiff base cross-linking reaction between adipic dihydrazide (ADH)-modified poly(l-glutamic acid) (PLGA-ADH) and benzaldehyde-terminated poly(ethylene glycol) (PEG-CHO). The effects of the mass fraction and the molar ratio of −CHO/–NH2 on the gelation time, mechanical properties, equilibrium swelling, and in vitro degradation of the hydrogels were examined. The PLGA/PEG hydrogels cross-linked by dynamic Schiff base linkages exhibited good self-healing ability. Additionally, the PLGA/PEG hydrogels had good biocompatibility with bone marrow-derived mesenchymal stem cells (BMSCs) and could effectively support BMSC proliferation and deposition of glycosaminoglycans and upregulate the expression of cartilage-specific genes. In a rat cartilage defect model, PLGA/PEG hydrogels significantly promoted new cartilage formation. The results suggest the prospect of the PLGA/PEG hydrogels in cartilage tissue engineering.
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JOURNAL OF CATALYSIS
·
2023
·
IF 7.3
Yuexia Wang,Qibin Yao,Bowen Xu,Kehang Lin,Mengshan Deng,Xinqing Lu,Rui Ma,Yanghe Fu,Weidong Zhu
Although the oxidative hydration of ethylene with hydrogen peroxide (H 2 O 2 ) to ethylene glycol (EG) over Ti-MWW zeolites take advantages of step-saving and facile operation, both H 2 O 2 utilization efficiency and EG yield are relatively low, because some extra-framework octahedral Ti species are usually formed in the Ti-MWW zeolites synthesized by prevailing methods, which are detrimental to selective oxidation . In the present work, an acid-modulated isomorphous substitution method, i.e. , layered borosilicate MWW-type zeolite (ERB-1) treated with HNO 3 aqueous solution containing tetrabutyl orthotitanate (TBOT), is developed to synthesize a Ti-MWW zeolite without extra-framework octahedral Ti species under the optimized synthesis conditions. In combination with the results from extensive characterizations for the synthesized zeolites, it is found that in the zeolite prepared by the currently developed synthesis method there are more open Ti(OSi) 3 OH sites formed, resulting in the stronger Lewis acidity that is very helpful to EG production from the oxidative hydration of ethylene with H 2 O 2 , compared to the one synthesized by the prevailing method. Moreover, the developed catalyst is recyclable after the regeneration of the deactivated zeolite by calcination at high temperatures. Therefore, it is anticipated that the currently developed Ti-MWW might be industrially applicable in the one-pot synthesis of EG from ethylene with H 2 O 2 .
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CONSTRUCTION AND BUILDING MATERIALS
·
2023
·
IF 7.4
Bingzheng Jiang,Dong Chen,Li Wang,Wantai Yang
In this research, a novel method was developed to synthesize methoxy polyethylene glycol-grafted sulfonated poly(maleic anhydride- alt -styrene) (SPMS-g-mPEG) as cement superplasticizers. The method includes three main steps: 1) self-stabilized precipitation polymerization (2SP) of styrene and maleic anhydride for PMS microspheres; 2) gas-solid heterogeneous sulfonation reaction (GSR) of gaseous SO 3 with PMS microspheres; 3) intramolecular sulfonic acid-catalyzed esterification reaction of mPEG with sulfonated PMS (SPMS). GSR can achieve uniform sulfonation of PMS microspheres, while overcoming the inherent drawbacks of the traditional homogeneous solution sulfonation process. SPMS and SPMS-g-mPEG with different structural parameters and uniform structure were successfully prepared and their effects on the fluidity and fluidity retention of cement pastes were systematically compared. For the samples demonstrating the best dispersing ability, the hydration heat and setting time of cement pastes, adsorption kinetics and compressive strength of mortar samples were determined further. Our work provides an innovative and effective approach to superplasticizers with outstanding properties and its uniform structure facilitates the investigation on the relationship between structure and properties.
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ENERGY
·
2022
·
IF 8.857
Lihua Peng,Luomeng Chao,Ziqing Xu,Haibin Yang,Dapeng Zheng,Boxuan Wei,Changwei Sun,Hongzhi Cui
The energy shortage crisis is one of the main challenges facing human society. Energy storage blanket (ESB) based on phase change material (PCM) and transparent heat-insulating glass (HIG) based on selective light-absorbing materials show great potential in regulating temperature and reducing building energy consumption. However, the stability of ESB and HIG is insufficient, and there is often a substantial indoor temperature difference when ESB and HIG are applied alone. In this research, stability-enhanced HIG and ESB were prepared. The oxidation and the decline in the heat insulation ability of HIG in air were solved by coating SiO 2 film on the surface of K x WO 3 nanoparticles. The low thermal conductivity and the deformation during the phase change process of ESB were solved by encapsulating PCM with expanded graphite . The combined use of HIG and ESB (HIG-ESB) reduces the temperature difference in the test room from 5.9 to 0.5 °C and the maximum indoor temperature from 50.5–56.4 °C to 28.5–28.9 °C. The energy-saving rates of ESB, HIG, and HIG-ESB in different climatic regions of China are evaluated by numerical simulation. The results show that ESB can save energy in all regions, while the HIG increases energy consumption in cold areas and can achieve a stronger energy-saving effect than ESB in mild areas such as Hong Kong and Changsha.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2022
·
IF 4.326
Dongyue Wang,Qiuchen Wang,Wenji Zheng,Yan Dai,Xuehua Ruan,Xiangcun Li,Gaohong He
Pore engineering of metal-organic frameworks is essential to achieve selective sieving of gas molecules for mixed matrix membranes (MMMs). In this work, poly(ethylene glycol) diglycidyl ether (PEGDGE) small molecules were proposed to be immobilized into the cage of NH2-MIL-101(Cr) (NMIL-101) by a covalent bond. A precise adjustment in pore size of NMIL-101 was achieved through controlling PEGDGE content. The ring-opening reaction is confirmed to happen between epoxy and amino groups by Fourier transform infrared spectroscopy. CO2/N2 selectivity increases gradually with increasing PEGDGE content, demonstrating the effective screening of the pores regulated by PEGDGE. When PEGDGE content is 20.8 wt %, the MMMs have the best gas separation performance, with a CO2 permeability of 111.6 Barrer and a CO2/N2 selectivity of 72.8, which are increased by 31.2% and 30.8%, respectively. Specifically, compared with PEGDGE13.0/NMIL-101-based MMM without a ring-opening reaction, PEGDGE11.1@NMIL-101 presents an improvement in both CO2 permeability and selectivity, indicating the necessity of in situ anchoring of PEGDGE.
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CHEMISTRY OF MATERIALS
·
2022
·
IF 10.508
Qun Yu,De-chang Li,Zhengbin Tian,Chongzhi Zhu,Chengli Jiao,Qian Zhang,Yanping Chen,Yihan Zhu,Heqing Jiang,Jian Liu,Guang-Hui Wang
Single-hole hollow carbon nanospheres (HCH) possess unique properties that combine the advantages of a hollow cavity and an opening hole in the shell, making them very attractive in various applications. However, it is still a challenge to synthesize HCH via a facile and scalable route. Herein, we develop a poly(ethylene glycol) (PEG)-assisted emulsion-templating method to synthesize HCH, involving only a hydrothermal process and pyrolysis. In the emulsion system, the PEG molecules can be used as a reverse demulsifier to induce the formation of hollow structures with a closed shell (HCS, PEG-1000), a single hole in the shell (HCH, PEG-2000), and a bowl-like shell (HCB, PEG-4000). It is found that HCH exhibits higher adsorption capacities (2–4 times higher than those of HCS) and faster adsorption rates toward large molecules (e.g., Congo red), indicating the intensification of liquid-phase adsorption induced by the single-hole hollow structure, which can promote mass transfer and simultaneously enhance the adsorption capacity.
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FOOD RESEARCH INTERNATIONAL
·
2022
·
IF 7.425
Luhui Wang,Zihao Wei,Changhu Xue
Propylene glycol alginate (PGA) was added to improve the stability and delivery performance of carboxymethyl starch (CMS)-stabilized emulsion. In the first instance, the CMS/PGA complexes were characterized, which proved that the formation of CMS/PGA complexes mainly depended on hydrogen bonding, and the CMS/PGA complexes showed porous networks. The CMS/PGA complexes were more hydrophobic than CMS, and the interaction of CMS with PGA enhanced the thermal stability of CMS. Next, the effects of CMS/PGA complexes on the properties of emulsions were investigated, and the intestine-targeted delivery potential of emulsions was evaluated through the in vitro release study as well. The droplet size of CMS/PGA complex-stabilized emulsions gradually decreased and the encapsulation efficiency (EE) improved with increasing the PGA content in CMS/PGA complexes. The addition of PGA also greatly improved the physical stability of emulsions, including anti-flocculation and anti-coalescence stabilities. All emulsions exhibited non-Newtonian pseudoplastic properties. Furthermore, the emulsions stabilized by CMS/PGA complexes showed reduced curcumin (Cur) release in the simulated gastric fluid (SGF), whereas exhibited sustained release in the α-amylase-containing simulated intestinal fluid (SIF). These results demonstrated that the emulsion stabilized by CMS/PGA complex was able to control and modulate the release of Cur in the gastrointestinal tract, and was therefore a promising intestine-targeted delivery system for Cur.
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高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2022
·
IF 3.269
Guangyuan Chen,Yunhai Shi,Rongchun Shen,Wei Li,Jinghong Zhou
Two kinds of ketones , 5-methyl-2-hexanone and di-isobutyl ketone were selected as the extraction agents for separating the azeotrope of ethylene glycol (EG)and 1,2-butanediol (1,2-BDO). By comparing the results of preliminary extraction experiments under 303.15 K and normal pressure, 5-methyl-2-hexanone was the better one. And the Liquid-liquid equilibrium data of EG + 1,2-BDO + 5-methyl-2-hexanone ternary system were successively measured at 293.15 K and 313.15 K. The distribution coefficient ( K 2 ) and selectivity coefficient ( S ) of 1,2-BDO were calculated from the experimental data. The LLE data were correlated by NRTL and UNIQUAC activity models with the authorized Aspen Plus software. The root mean square deviations ( RD ) between the experimental and calculated values were all less than 0.7%, which means they were consistent with each other very well.
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高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Zitong Yuan,Chuanxin Ma,Mengao Jia,Kun Qian
Overused agrochemicals threaten the environment and human health. Nanotechnology has shown great potential for maintaining or minimizing environmental issues in agriculture . Herein, a polyethylene glycol-coated copper nanoclusters (PEG@Cu NCs) has been developed for efficient utilization by tobacco. The NCs showed the superior antifungal activity against Alternaria alternata , achieving comparable activity using a dose almost 35-fold lower than that of 46% copper hydroxide water power (WP). More importantly, PEG@Cu NCs exhibited excellent therapeutic potential via xylem delivery. In the meantime, promising bioavailability of the NCs was achieved, which could be absorbed by tobacco seedlings via roots and foliar tissues (epidermal and mesophyll cells). In addition, the biosafety of PEG@Cu NCs was investigated in tobacco and earthworms. Both root exposure (1.27–3.17 mg L −1 ) and leaf exposure (1.27–6.33 mg L −1 ) to PEG@Cu NCs had no negative effects on tobacco growth. The acute toxicity of PEG@Cu NCs to earthworms was low, as determined by the 7 day-LC 50 value of 46.253 mg kg −1 and 14 day-LC 50 value of 30.187 mg kg −1 . Overall, such NCs are expected to be a competitive alternative to Cu-based fungicides in sustainable agriculture due to their superior antifungal properties , excellent biocompatibility, and high efficiency bioavailability.
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