MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 10
·1-11
·
IF 5.3
Li Ningzhen,Zhang Zhenteng,Tian Tingting,Sun Luyu,Xu Lixiao,Wang Jiasheng,Hui Ni
A cortisol biosensor was developed based on double-conducting polymer nanowires, which exhibits excellent conductivity, resistance to biological contamination, and outstanding sensing performance. The biosensor employs dual-mode electrochemical techniques, namely, differential pulse voltammetry (DPV) and chronoamperometry (CA), for the sensitive and low fouling detection of the glucocorticoid hormone cortisol. Experimental results demonstrated that the linear detection range of the biosensor in DPV mode was 1.0 × 10 −14 –1.0 × 10 −8 M, with a detection limit of 0.131 × 10 −14 M. In CA mode, the biosensor exhibited a detection range of 1.0 × 10 −13 –1.0 × 10 −7 M and a detection limit of 0.313 × 10 −13 M. The biosensor was successfully utilized for the rapid detection of cortisol in human saliva. The combination of a high-specificity cortisol aptamer and functionalized double-conducting polymer nanowires ensured the exceptional specificity and sensitivity of the biosensor in detecting real biological samples. Graphical Abstract
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GREEN CHEMISTRY
·
2024
·Vol. 26
·期 10
·5954-5965
·
IF 9.3
Lijuan He,Long Chen,Yingxia Nie,Minglu He,Guixiang Wu,Yan Li,Hanjing Tian,Heng Zhang
Developing efficient and environmentally friendly heterogeneous catalysts for sustainable biodiesel preparation is considered a viable manner to meet global energy demand and alleviate environmental concerns. In this work, a series of novel mesoporous organic–inorganic hybrid clay materials ILs-OMt-x (x, the use of pyrrole mass, x = 0.4, 0.6, and 0.8 g), were fabricated by pyrrole in situ polymerization utilizing ionic liquid (IL)-grafted biocompatible montmorillonite (Mt) as a modified matrix under relatively mild conditions. Among these clay materials, it was determined that ILs-OMt-0.6 had favorable physicochemical properties, including large specific surface area (SBET, 80.41 m2 g−1), layered mesoporous structure (12.28 nm), multiple acid sites, and relatively strong acid intensity (1.63 mmol g−1). As a result, ILs-OMt-0.6 showed outstanding catalytic performance in biodiesel preparation, and the highest biodiesel yield of 97.02% was obtained after single-factor and response surface methodology (RSM) optimization (6.4 wt% catalyst dosage, 15.2 : 1 molar ratio of methanol to oleic acid (OA), 6.3 h, 83.0 °C). In addition, kinetics study further confirmed its lower activation energy compared with pristine Mt and commercial resin Amberlyst-15, and a possible esterification mechanism was also proposed. Importantly, ILs-OMt-0.6 showed excellent substrate versatility, displaying satisfactory catalytic performance in trans(esterification) of other fatty acids and raw non-edible oils. It is worth mentioning that the physicochemical properties of as-synthesized biodiesel conformed with international standards, and its life-cycle cost (LCC) indicated the good economic viability of ILs-OMt-0.6 for efficient catalytic biodiesel production. This study reveals a promising application path of novel hybrid materials with favorable physicochemical properties in biodiesel production and provides new paths for fabricating Mt-based catalysts with high efficiency and stability for the sustainable development of liquid biomass refining technology.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Yuhao Chen,Haixiang Sun,Peijian Wang,Qian Yu,Yuhui Niu,Sihui Tang,Tengfang Zhang,Bangzhen Liu,Q. Jason Niu
Highly permeable thin film composite (TFC) reverse osmosis (RO) membranes with abundant free volume are desirable for water treatment. However, the strategy of controlling the microstructure of the separation layer with high free volume rate is still a challenge. In this work, a modified strategy for the preparation of high-performance TFC RO membrane with inverse diffusible polypyrrole nanoparticles (PPYN) as organic phase additive was developed. The combination of PPYN and trimesoyl chloride (TMC) would diffuse backwards from the organic phase into the aqueous phase during the reaction process to disrupt the normal interfacial polymerization (IP) and thus introduce more free volume in the RO membrane due to the nanobubbles from violent reactions. Moreover, the thickness of the modified membrane decreased and the hydrophilicity increased based on the modulation of IP by PPYN, which facilitated the water molecules to transport. The prepared RO-PPYN membranes showed nearly three times the flux compared with the pristine RO membrane without sacrificing separation selectivity. Furthermore, the anti-biofouling property of the modified membrane was also improved. This work successfully demonstrated the potential use of PPYN as an organic filler to enhance the performance of seawater desalination in RO membranes. Our modification strategy provides an efficient and convenient way to prepare novel RO membranes with high permeability.
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Processes
·
2025
·Vol. 13
·期 2
·530
·
IF 2.8
Yuchen Bai,Ningke You,Hongyu Tian,Xuebing Zhao
Hemp seed oil is nutritious. Besides cannabinoids, it has a higher Omega-3 fatty acid content, making it an ideal and healthy edible oil. Roasting is a key factor affecting the flavor of hemp seed oil. In this study, solvent-assisted flavor evaporation (SAFE) combined with gas chromatography–mass spectrometry (GC-O-MS) was used to analyze the volatile compounds of hemp seed oil after the hemp seeds were roasted at different temperatures (120 °C, 140 °C, 160 °C, 180 °C). α-pinene, (1S)-(1)-β-pinene, myrcene, and (E)-β-ocimene, which are typical odorants for herbs and fresh flavors, had an active odor value (OAV) ≥ 1. The sweet, nutty, and toasty flavors became more pronounced as the temperature increased. 2-pentylfuran provided the caramel flavor, and 2,5-dimethylpyrazine, 2-ethyl-6-methylpyrazine, and 2-ethyl-5-methylpyrazine provided the toasty flavor. The combination of sensory evaluation and data analysis was effective in differentiating the odors of hemp seed oil extracted at different temperatures. Reconstitution and deletion experiments showed that these odorants could mimic the overall aroma profile. This article provides a theoretical basis for the effect of over-roasting on the flavor of hemp seed oil.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2025
·
IF 2.6
Sun Yiwei,Luo Yuting,He Yuyang,Wang Haoxiang,Wang Ruoyu,Lu Mengqi,Li Ke,Wu Siqi,Wei Sucan,Song Huiqiao,Xu Dongpo
A highly efficient electrochemical molecularly imprinted sensor for the detection of chloramphenicol (CAP) was prepared using carbon nanofibers (CNFs). The conductivity and large surface area of CNFs improved the electrochemical detection performance while providing more binding sites for chloramphenicol molecularly imprinted polymers. CNF@MIP was prepared using polypyrene as the functional monomer and chloramphenicol as the template molecule. The electrochemical performance of CNF@MIP was evaluated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Under optimized conditions, CNF@MIP exhibited a wide detection range (0.1–100 nM), low detection limit (1.15 pM), and good selectivity, stability, and reproducibility. In addition, CNF@MIP can be used to detect chloramphenicol in milk samples.
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CHINESE JOURNAL OF CHEMISTRY
·
2012
·Vol. 30
·期 2
·259-266
·
IF 0.755
Zhihong Zhang,Guijuan Li,Fufeng Yan,Zhonghou Zhang,Shaoming Fang
In order to exploit the applications of polypyrrole (PPy) derivatives in biosensors and bioelectronics, the different immobilization mechanisms of biomolecules onto differently functionalized conducting PPy films are investigated. Pyrrole and pyrrole derivatives with carboxyl and amino groups were copolymerized with ω -( N -pyrrolyl)-octylthiol self-assembled on Au surface by the method of the chemical polymerization to form a layer of the copolymer film, i.e. , poly[pyrrole- co -( N -pyrrolyl)-caproic acid] (poly(Py- co -PyCA)) and poly[pyrrole- co -( N -pyrrolyl)-hexylamine] (poly(Py- co -PyHA)), in which the carboxyl groups in poly(Py- co -PyCA) were activated to the ester groups. Based on the structure characteristics, the immobilization/hybridization of DNA molecules on PPy, poly(Py- co -PyCA) and poly(Py- co -PyHA) were surveyed by cyclic voltammograms measurements. For differently functionalized copolymers, the immobilization mechanisms of DNA are various. Besides the electrochemical properties of the composite electrodes of PPy and its copolymers being detected before and after bovine serum albumin (BSA) adsorption, the kinetic process of protein binding was determined by surface plasmon resonance of spectroscopy. Since few BSA molecules could anchor onto the PPy and its copolymers surfaces, it suggests this kind of conducting polymers can be applied as the protein-resistant material.
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AICHE JOURNAL
·
2024
·
IF 3.5
Shuhuan Han,Zhengxuan Shao,Xiuhui Li,Jiwen Fu,Xiaofei Zeng
MoS 2 has been considered as a potential replacement for Pt-based catalysts in hydrogen evolution reaction. But the lack of sufficient active sites limits the intrinsic activity of MoS 2 -based catalysts. Here, we propose a general strategy to synthesize ultra-small MoS 2 nanosheets grown evenly on carbon substrates to maximize the active sites by exposing more edge positions and inducing MoS 2 phase transition. It is found that Ru can assist MoS 2 to grow vertically and uniformly on the surface of carbon substrates by in situ derivatization to improve the catalytic activity effectively. MoS 2 nanosheets on the substrates are much smaller and denser than those prepared without Ru or with other metal elements. Electrocatalysis results revealed that the number of active sites and conductivity of the optimized Ru-MoS 2 @CSs increase obviously, and the overpotential at 10 mA cm −2 is much lower than that of MoS 2 @CSs and metal (Co, Ni)-MoS 2 @CSs, respectively, at 1.0 M KOH.
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Journal of Materials Chemistry A
·
2024
·Vol. 12
·期 11
·6329-6340
·
IF 10.7
Bingjie Wen,Nizao Kong,Min Huang,Liqin Fu,Yexin Tian,Zhixiao Liu,Zhongchao Wang,Lezhi Yang,Fei Han
A single two-dimensional material often struggles to satisfy all the performance requirements of electrode materials for sodium-ion batteries. However, constructing a hierarchical heterogeneous two-dimensional stacking structure can effectively combine the advantages of multiple materials and make up for the insufficiency of a single element. This work applied a pre-intercalation–sulphuration concept and liquid-phase coating modification by constructing a hierarchical nano-flake/micro-lamellar complex structure. In this composite material, MoS2 nanosheets and V2C MXene layers overlap and interact to prevent nanoparticle agglomeration and micron flakes collapse simultaneously. The MoS2/MXene hierarchical structure is sandwiched between ultrathin and dense carbon layers to form a multifaceted conductive skeleton and a twofold protection mechanism. The coating reduces the electrolyte contact area and prevents the escape of polysulfide byproducts. Accordingly, the designed MSVC@C demonstrates superior Na+ storage capacities (612.4 mA h g−1 at 0.5 A g−1 after 600 cycles) and outstanding rate performance (304.42 mA h g−1 at 10 A g−1). Experimental results and theoretical calculations verify that the MoS2 and V2C heterostructure promotes the electrochemical performance owing to the better electronic conductivity and lower ion diffusion energy barrier. Moreover, this structure optimization strategy applies to various MXene guests (e.g., V2C and Nb2C) to prepare a variety of hierarchical nano–micro structures that are expected to be promising two-dimensional electrode materials for SIBs with application prospects in the future.
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ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Ahmed Elhassan,Jialu Li,Ibrahim Abdalla,Ziao Xu,Jianyong Yu,Zhaoling Li,Bin Ding
The pursuit of eco-friendly electromagnetic wave absorption (EMWA) materials with multifunctional capabilities has garnered significant attention in practical applications. However, achieving these desired qualities simultaneously poses a significant challenge. This study introduces a single-step calcination and chemical polymerization process to obtain an environmentally friendly ant-nest-inspired hybrid composite by optimizing conductive polypyrrole nanotubes (PNTs) within a 3D carbonaceous structure. The biomimetic composite forms a highly efficient conductive network, providing a pathway for free electrons within the carbonaceous barriers and enhancing the conduction loss. Remarkably, the EMWA performance of the composite achieves ultrathin (1.6 mm), wide effective absorption band (5.4 GHz), and strong absorption intensity (−67.6 dB) features. Moreover, due to the complex and intertwined 3D continuous network, the obtained samples exhibit excellent thermal insulation and superhydrophobic behavior by inhibiting heat transfer and preventing localized areas from being prone to water absorption. These findings not only offer a sustainable and low-cost production route for biomimetic carbonaceous composites but also demonstrate a high-efficiency absorber with great multifunctionality as a green alternative to traditional EMWA materials.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Ziyi Wang,Yuqin Wei,Zhaoli Xue,Lei Feng,Aijian Wang,Yan Sun,Chunsheng Li,Xinping Qiu,Long Zhao
Asymmetric metalloporphyrins are potential electrocatalysts to construct composites for efficient oxygen reduction reactions (ORRs) due to their inherent large dipole moment , which facilitates the charge separation. To find more effective molecular structures towards the ORRs, in particular their performance and electrolyte relationship, we rationally designed two A3B-type asymmetric cobalt porphyrin aPh-TCoP and aBA-TCoP with phenyl and benzoic acid as substituents, respectively. The ORR performance of the porphyrin-decorated carbon black composites was examined in five electrolytes at different pH values spanning from 0.7 to 13.7. It was found that aBA-TCoP/C exhibited better ORR activity and selectivity than aPh-TCoP/C in all solutions. Interestingly, both composites demonstrated their highest ORR activity in the pH13.7 electrolyte and exhibited 4-electron selectivity in the pH3.7 solution. This conclusion is drawn from a comprehensive analysis of various electrochemical properties , encompassing current density , reduction potentials, electron transfer numbers, and intermediate yields. The results illustrate the regulation of ORR properties by altering the electrolyte pH and a notable improvement in the ORR performance through the modification of porphyrin substituents. These findings offer a foundational understanding for the design of efficient metalloporphyrins and the attainment of controlled oxygen reduction in electrochemical devices .
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Polymer Chemistry
·
2015
·Vol. 6
·期 36
·6529-6542
·
IF 5.52
Jinxia An,Xiaomei Dai,Yu Zhao,Qianqian Guo,Zhongming Wu,Xinge Zhang,Chaoxing Li
To improve the pharmacokinetic and pharmacodynamic profiles of clinical anticancer drugs for cancer therapy, the development of effective drug delivery systems with precise biological functions is critically required. In the current study, we developed a PEGylated and core-cross-linked polymeric nanovehicle, LA-pDAGEA/pPEGA-b-p(DMDEA-co-BADS), with reduction- and pH-dependent degradation and fluorescence imaging function for tumor-targeted delivery of hydrophobic drugs. The multifunctional copolymers were synthesized using RAFT polymerization. By utilizing the intrinsic fluorescence of nanovehicles resulting from the boron–dipyrromethene dye-conjugated chain transfer agent (BODIPY), the cellular internalization process was exhibited. Cellular uptake and the competition inhibition assay show that the nanovehicles could be internalized into HepG2 cells via receptor-mediated endocytosis. Moreover, the drug-loaded nanovehicles were capable of significantly inhibiting cancer cell proliferation. Our newly developed multifunctional nanovehicles may thus facilitate the development of efficient drug delivery systems for application in diagnosis and therapy of cancer.
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Acta Biomaterialia
·
2015
·
IF 6.025
Xuemei Yao,Li Chen,Xiaofei Chen,Zhigang Xie,Jianxun Ding,Chaoliang He,Jingping Zhang,Xuesi Chen
Benefited from the high orientation of coordinated interaction, metallo-supramolecular materials have attracted enormous interest in many fields. Herein, a novel metallo-supramolecular nanogel (SNG)-based drug delivery system for synergistic chemo-photodynamic therapy is explored to enhance anticancer efficacy. It is fabricated by the metallo-supramolecular-coordinated interaction between tetraphenylporphyrin zinc (Zn-Por) and histidine. It can respond to tumor acid microenvironment to release the co-delivered anticancer drug and photosensitizer to kill the lesion cells. Zn-Por moieties in SNG keep the photosensitivity in the range of visible wavelength and possess the ability of generating active oxygen species for photodynamic therapy. The drug-loaded SNG provides a di-functional platform for chemotherapy and photodynamic therapy. Compared with the single chemotherapy of free doxorubicine (DOX) or photodynamic therapy of Zn-Por in SNG, DOX-loaded SNG with irradiation shows higher in vitro cytotoxicity and in vivo anticancer therapeutic activity, endowing the SNG with great potential in cancer treatments. The statement of significance A combination of multiple non-cross-resistant anticancer agents has been widely applied clinically. Applying multiple drugs with different molecular targets can raise the genetic barriers and delay the cancer adaption process. Multiple drugs targeting different cellular pathways can function synergistically, giving higher therapeutic efficacy and target selectivity. Overall, developing a combination therapeutic approach might even be the key to enhance anticancer efficacy and overcome chemo-resistance. Herein, a novel metallo-supramolecular nanogel (SNG) is fabricated by the metallo-supramolecular-coordinated interaction between tetraphenylporphyrin zinc (Zn-Por) and histidine. The DOX-loaded SNG provides a di-functional platform for chemotherapy and photodynamic therapy because it can respond to tumor acid microenvironment to release the co-delivered anticancer drug and photosensitizer to kill the lesion cells.
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