JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·
IF 10.6
Majid Sharifi,Majid Salehi,Somayeh Ebrahimi-Barough,Morteza Alizadeh,Hossein Kargar Jahromi,Mohammad Kamalabadi-Farahani
Numerous conduits have been developed to improve peripheral nerve regeneration. However, challenges remain, including remote control of conduit function, and programmed cell behaviors like orientation. We synthesized Fe 3 O 4 -MnO 2 @Zirconium-based Metal-organic frameworks@Retinoic acid (FMZMR) core-shell and assessed their impact on Schwann cell function and behavior within conduits made from decellularized human umbilical arteries (DHUCA) under magnetic field (MF). FMZMR core-shell, featuring a spherical porous structure and catalytic properties, effectively scavenges radicals and facilitates controlled drug release under MF. The histology of the DHUCA indicates effective decellularization with adequate tensile strength and Young’s modulus for sciatic nerve regeneration. In-vitro results demonstrate that FMZMR core-shell is biocompatible and promotes Schwann cell proliferation through remotely controlled drug release. Furthermore, its synergy with MF enhances cell orientation and increases neurite length by ~ 1.93-fold. Functional and histological evaluations indicate that the FMZMR core-shell combined with MF promotes nerve regeneration, decreases muscle atrophy, and enhances new neuron growth and myelin formation, without negatively affecting vital tissues. This study suggests that the synergistic effect of FMZMR core-shell with MF can alleviate some of the treatment challenges.
研究领域:
生物材料学
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神经科学
·
组织工程学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Sijie Xie,Yongbo Chen,Zhijie Bi,Shasha Jia,Xiangxin Guo,Xiangdong Gao,Xiaomin Li
A carefully designed energy storage smart window (ESSW) was successfully demonstrated with transparent-to-dark electrochromic behavior and improved pseudocapacitive performance that constructed by Mo-doped WO 3 film electrode and MnO 2 nanoflake film electrode. These two electrodes were all synthesized by facile electrodeposition method which is simple, economic and easy-to-production. The proposed ESSW could change its color between transparent and dark with over 60% optical modulations in all visible bands (420–800 nm), which is satisfactory to the applications toward energy saving. Also, the areal capacitance of the ESSW reaches 19.1 mF cm −2 with working voltage window of 2.0 V so that just one single ESSW could power an LED bulb for more than 90 s. The complementary electrochromic behavior of the two electrodes guarantees the commendable electrochromic performance of the proposed ESSW, and the well-matched working potentials and areal capacitances of the asymmetric electrodes improve the pseudocapacitive performance. Such ESSW could have widely future applications toward energy saving and storing fields.
研究领域:
材料科学
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能源技术
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产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Fan Xu,Jing Zhao,Feng Xiao,Donghua Wu,Xinze Li,Lei Wang,Qihang He,Xiaowei Zuo,Shengping Yuan,Shengbing Wang,Ping He
Corrosion and passivation of zinc electrode severely affect discharge performance of alkaline Zn-MnO 2 batteries. To address this issue, this work introduces dodecyl dimethyl benzyl ammonium bromide (DDBAB) as an additive in KOH electrolyte to inhibit corrosion and passivation processes of zinc electrode. Results demonstrate that DDBAB reduces contact angle at electrolyte-zinc electrode interface, thereby improving wettability of KOH electrolyte on zinc electrode surface. Scanning electron microscopy images reveal effective inhibition of corrosion on zinc electrode surface. Concurrently, the corrosion inhibition efficiency of zinc electrode reaches 98.38% in KOH electrolyte with 60 ppm of DDBAB additive. Furthermore, the presence of DDBAB positively shifts both the active dissolution potential and passivation potential of zinc electrode, thereby effectively delaying its passivation. Moreover, at a current density of 50 mA g −1 , the specific discharge capacity of battery improves by 26.80%. These results demonstrate that effective inhibition of zinc electrode corrosion and passivation is achieved by protective layer formed by DDBAB on surface. This work provides a feasible method to inhibit corrosion and passivation of zinc electrode in alkaline Zn-MnO 2 battery.
研究领域:
电化学
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电池技术
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材料科学
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腐蚀科学
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产品关联
DOI
高影响因子
Chemistry-An Asian Journal
·
2018
·Vol. 13
·期 5
·545-551
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IF 3.692
Xu Ou,Qi Li,Dan Xu,Jiangna Guo,Feng Yan
Graphical N-CNTs@MnO 2 nanocomposites have been successfully prepared by in situ growing MnO 2 nanosheets on N-doped carbon nanotubes (CNTs) derived from polypyrrole nanotubes. The as-prepared nanocomposites showed good capacitance and cycling stability as supercapacitor electrode materials. Nitrogen-doped porous carbon nanotubes@MnO 2 ( N -CNTs@MnO 2 ) nanocomposites are prepared through the in situ growth of MnO 2 nanosheets on N-CNTs derived from polypyrrole nanotubes (PNTs). Benefiting from the synergistic effects between N-CNTs (high conductivity and N doping level) and MnO 2 nanosheets (high theoretical capacity), the as-prepared N-CNTs@MnO 2 -800 nanocomposites show a specific capacitance of 219 F g −1 at a current density of 1.0 A g −1 , which is higher than that of pure MnO 2 nanosheets (128 F g −1 ) and PNTs (42 F g −1 ) in 0.5 m Na 2 SO 4 solution. Meanwhile, the capacitance retention of 86.8 % (after 1000 cycles at 10 A g −1 ) indicates an excellent electrochemical performance of N-CNTs@MnO 2 prepared in this work.
研究领域:
材料科学
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能源存储
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DOI
高影响因子
TALANTA
·
2016
·
IF 4.035
Fengli Qu,Haimeng Pei,Rongmei Kong,Shuyun Zhu,Lian Xia
Using sterculia lychnophora seeds as precursors for the first time, fluorescent carbon dots (CDs) were synthesized by simple hydrothermal treatment . The quantum yield of as-synthesized CDs was 6.9% by using quinine sulfate as the reference. The fluorescence of CDs could be effectively quenched by a MnO 2 nanosheet based on fluorescence resonance energy transfer (FRET). Ascorbic acid (AA) could reduce MnO 2 to Mn 2+ and result in the destruction of the MnO 2 nanosheets, which could induce the fluorescence recovery of the CDs. In particular, alkaline phosphatase (ALP) could bio-catalyze acid 2-phosphate (AAP) hydrolysis to AA. Here, an efficient fluorescence probe based on a CDs-MnO 2 nanosheet for rapid and selective detection of ALP was reported for the first time. Excellent performance for the detection of ALP was observed with high sensitivity and a detection limit of 0.4 U/L owing to the low background. The detection of ALP in human serum was conducted with satisfactory results, demonstrating its potential applications in clinical diagnosis.
研究领域:
生物化学
·
医学诊断
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
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2016
·
IF 7.476
Wei Huang,Yuequan Deng,Yi He
Here we report a unique visual colorimetric sensor array for discrimination of antioxidants in serum based on MnO 2 nanosheets-3,3′,5,5′-tetramethylbenzidine (TMB) multicolor chromogenic system. The absorbance values of the system at 370, 450, and 650 nm provide three cross-reactive sensing elements. The presence of antioxidant will inhibit the reaction between TMB and MnO 2 nanosheets due to the presence of the competitive reaction of MnO 2 nanosheets and antioxidants. Different antioxidants containing uric acid , glutathione , ascorbic acid , cysteine, and melatonin have distinct reducing ability, producing a differential inhibition of MnO 2 nanosheets-TMB system, and therefore generating distinct colorimetric response patterns at 370, 450, and 650 nm. The obtained patterns for each antioxidant at a concentration of 20 μM were successfully discriminated using principal component analysis both in buffer and when spiked into fetal bovine serum (FBS). The identification accuracy of 45 unknown samples was found to be 100%. Remarkably, this sensor assay can visually discriminate antioxidants in diluted FBS with the naked eye.
研究领域:
分析化学
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生物化学
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纳米技术
·
传感器
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DOI
PubMed
高影响因子
Analytical Methods
·
2016
·Vol. 8
·期 48
·8492-8497
·
IF 1.915
Wenjun Ouyang,ZhenHua Liu,GuiFeng Zhang,Zheng Chen,Longhua Guo,Zhenyu Lin,Bin Qiu,Guonan Chen
MicroRNAs (miRNAs) have attracted enormous interest due to their involvement in complex regulatory functions and for being closely linked to some cancers. Thus, qualitative and quantitative detection of miRNAs has become an urgent necessity. In this study, we report an enzyme-free fluorescent biosensor for miRNA-21 detection based on MnO2 nanosheets and catalytic hairpin assembly amplification. Results showed that the detection limit for miRNA-21 was 0.33 nM (S/N = 3) and the linearity range was from 1 to 50 nM. Compared with traditional methods, such strategy is convenient, rapid, and low-cost and it can have a promising potential for miRNA detection in cancer.
研究领域:
生物化学
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分子生物学
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癌症研究
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纳米技术
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DOI
高影响因子
WATER RESEARCH
·
2017
·
IF 6.942
Tian Tian,Sen Qiao,Cong Yu,Yihui Tian,Yue Yang,Jiti Zhou
Recently, the influence of metal oxide nanoparticles (NPs) on methanogenesis in anaerobic digestion has drawn much attention, however, the changes in NPs and functioning consortia within the methanogenic community are usually not investigated. Therefore, the methanogenesis performance, NPs transformation and methanogenic community development in anaerobic digester sludge under MnO 2 NP supplementation were demonstrated in this study. MnO 2 NPs (400 mg/gVSS) stimulated the methane (CH 4 ) yield by 42% for a final CH 4 proportion of 81.8% of the total gas production. Meanwhile, the coenzyme F 420 and INT-electron transport system activities showed positive correlation with MnO 2 concentration. Microbial Mn reduction and oxidation occurred in conjunction with methanogenesis, resulting in transformation of the shape of the MnO 2 NPs from wire-like to globular particles. Microbial community analysis indicated that the relative abundances of genera Methanobacterium , Methanosaeta, and Methanosarcina were higher in the presence of MnO 2 NPs. Moreover, a new and different crucial synergy within the methanogenic community was formed with low-abundance consortia driving Mn respiration coupled to methanogenesis in anaerobic digestion. To our knowledge, this is the first report on transformation of metal oxides NPs combined with syntrophic community development in studies focusing on methanogenesis in response to NPs.
研究领域:
环境微生物学
·
纳米生物学
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DOI
PubMed
高影响因子
Journal of Energy Storage
·
2026
·
IF 10.7
Jiaqi Pan,Shaokang Guo,Xingyu Ni,Xutong Sun,Wenhao Yue,Yongchen Kong,Yonghui Ma,Chunliang Zhou,Junnan Liu
Sodium-ion batteries (SIBs) are considered a promising alternative to lithium-ion batteries (LIBs) due to their abundant resources and low cost. However, the relatively large radius and mass of sodium ions can lead to structural degradation and volume changes in the electrode materials during charging and discharging processes, which limits their practical applications. In this paper, we successfully prepared carbon and MnO 2 co-coated Na 3 V 2 (PO 4 ) 2 F 3 (NVPF/C@ M-x, x = 0, 1, 3, 5 wt%) cathode materials using sol-gel method and suspension coating method. We systematically studied the physical and chemical effects of the MnO 2 coating, as well as the electrochemical performance of the materials. The results demonstrate that an optimal MnO₂ coating (1 wt%) forms a uniform interfacial layer, which not only suppresses Na + dissolution and side reactions but also enhances electronic conductivity and structural stability. NVPF/C@M-1 exhibits a reversible specific capacity of 129.09 mAh g −1 at 0.1C and maintains a capacity of 59.44 mAh g −1 at 10C. Furthermore, after 300 cycles at 1C and 500 cycles at 5C, the capacity retention rates are 85.96% and 89.34%, respectively. Kinetic analysis reveals that the MnO 2 coating significantly reduces the charge transfer resistance (R ct ) and increases the sodium ion diffusion coefficient (D Na+ ), thereby optimizing the rate performance and cycling stability of the materials. Additionally, the MnO 2 and C co-coating structure significantly improves the low-temperature performance, with the NVPF/C@M-1 electrode maintaining 90.43% capacity retention even at −30 °C, far superior to the uncoated sample's 64.13%. The NVPF/C@M-1 cathode demonstrates significantly enhanced overall performance in sodium-ion full-cell tests. It delivers an initial discharge capacity of 107.78 mAh g −1 at 1C, maintains a capacity retention rate of 95.07% after 100 cycles, and retains a discharge capacity of 81.63 mAh g −1 even at the high rate of 5C. This study provides an effective strategy for developing high-performance cathode materials for sodium-ion batteries.
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Jiaqi Li,Dongfeng He,Ruize Zhang,Binbin Tan,Jiang Wang,Jing Wang,Junrong Chen,Hui Wang,Wenlei Wang
5-Hydroxymethylfurfural (HMF) serves as a key platform molecule for green photocatalytic oxidation to produce high-value-added chemicals. Addressing the critical need for efficient photocatalytic conversion of HMF to 2,5-furan dicarboxylic acid (FDCA) under mild conditions, this study proposes and constructs a synergistic ternary composite photocatalytic system. By incorporating porous organic polymers (POPs) into oxygen-vacancy-rich MnO 2-x /Cu 2 O, the MnO 2-x @POPs@Cu 2 O composite photocatalyst was synthesized. This composite catalyst demonstrated remarkable photocatalytic performance under ambient conditions, achieving 71.8% conversion of HMF and 18.5% yield of FDCA. Results indicate that POPs not only selectively enrich reactants by forming dynamic imine bonds with HMF via its surface (–NH 2 ) functional groups, but also significantly enhance interfacial charge separation and transport through a locally embedded electric field generated by its highly negatively charged triazine framework, thereby accelerating the Mn-Cu bimetallic redox cycle. Furthermore, electron paramagnetic resonance (EPR) and density functional theory (DFT) calculations confirmed that introducing POPs effectively reduces O 2 adsorption energy, promotes molecular oxygen activation, and enhances reactive oxygen species generation. This study provides a novel strategy for designing low-cost, high-efficiency multicomponent photocatalysts for biomass refining.
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产品关联
DOI
高影响因子
Materials
·
2026
·Vol. 19
·期 2
·
IF 3.2
Mengjie Huang,Baihui Zhang,Xiangyu Jiang,Maojie Jiang,Peng Yin,Xuan Fang,Yanna Lin,Fuqiang Ma
This study addresses the issues of poor stability and difficulty in recovery of free horseradish peroxidase (HRP) by developing a multi-level composite immobilized carrier that combines high loading capacity with long-term stability. The SiO2@MnO2@MAF-7 core–shell structured carrier was prepared via a solvothermal self-assembly method. Three immobilization strategies—adsorption, covalent cross-linking, and encapsulation—were systematically compared for their immobilization efficacy on HRP. The material structure was analyzed using techniques such as specific surface area analysis (BET), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) to characterize the material structure. Enzyme kinetic parameter determination experiments were conducted to systematically evaluate the performance advantages of the immobilized enzyme. BET analysis showed that SiO2@MnO2@MAF-7 had a specific surface area of 251.99 m2/g and a mesoporous area of 12.47 nm, and its HRP loading was 50.37 U/mg (immobilization efficiency 85.03%). Compared with free HRP, the Km value of the immobilized enzyme was decreased by 42%, the activity retention rate was increased by 35–50% at 80 °C and pH 4–9, and the activity was maintained by 65% after five repeated uses. In this study, MAF-7 was combined with MnO2/SiO2for HRP immobilization for the first time, and the triple effect of rigid support-catalytic synergy-confined protection synergistically improved the stability of the enzyme, providing a new strategy for the industrial application of oxidoreductases.
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产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 35
·15066-15070
·
IF 3.288
Lijuan Chen,Haiyan Gao,Yan Bai,Wei Wei,Junfeng Wang,Georges El Fakhri,Meiyun Wang
Colorimetric analysis is a method for determining the concentration of a chemical compound in a solution using a color reagent. Here, we developed a low cost and rapid approach for cascade biosensing of glucose in human serum samples by taking into account the advantages of the excellent selectivity of natural glucose oxidase and the splendid catalytic properties of nanozymes. Hollow manganese dioxide nanoparticles (H-MnO2 NPs) assembled by abundant nanosheets were successfully synthesized via a one-pot reduction strategy, demonstrating exhibited splendid oxidase-like activities. In the colorimetric analysis system, glucose oxidase can oxidize glucose to produce H2O2, which can consume the proposed H-MnO2 NPs in acid medium. Then, the residual H-MnO2 NPs can catalyze the 3,3′,5,5′-tetramethylbenzidine molecules and then produce a colorimetric signal at 652 nm, which can quantificationally reflect the concentrations of glucose. The lower limit of detection of glucose is 0.84 μM and the system has a linear response up to 200 μM. This method provides suitable specificity and practical feasibility to be used for the routine analysis of human serum samples.
研究领域:
生物化学
·
医学诊断
·
纳米技术
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DOI
高影响因子
危险品化学品经营许可证（带存储）