JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2022
·Vol. 33
·期 29
·23116-23127
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IF 2.779
Zhang Yu,Xiao Lei,Peng Sen,Li Qiang,Yi Tulin,Liu Weichun,Sun Yuxin
Ba[(Zn 1- x Mg x ) 1/3 Nb 2/3 ]O 3 ( x = 0 ~ 0.9) ceramics were prepared by the traditional solid-phase reaction sintering method. In this paper, the effects of MgO doping on the shrinkage, density, phase composition, crystal structure, microstructure, and microwave dielectric properties of Ba(Zn 1/3 Nb 2/3 )O 3 (BZN) ceramics were investigated. The phase constituents, crystal structure, and microstructure of the ceramics were studied by X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscope (SEM), and energy dispersive spectrometer (EDS). The results showed that Ba(Zn 1/3 Nb 2/3 )O 3 as the main phase, and the secondary phase Ba 5 Nb 4 O 15 was detected with high MgO content ( x > 0.3). However, the appearance of secondary Ba 5 Nb 4 O 15 directly led to the deterioration of the microwave dielectric properties of the samples. Ba[(Zn 1– x Mg x ) 1/3 Nb 2/3 ]O 3 ( x = 0.3) ceramics sintered at 1500 °C for 4 h possessed superior dielectric properties: ε r = 36.31, Q × f = 111,326 GHz, τ f = + 12.1 ppm/°C. Such the ceramics could be used to make dielectric resonators and stable oscillators.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Jie Zhou,Hao Liu,Chao Xiong,Peng Hu,Hao Wang,Xuyu Wang,Hongbing Ji
Propane dehydrogenation (PDH) has been a promising method to satisfy the increasing demand for propylene, but Pt-based catalysts always suffer from sintering and coke formation. Developing stable and efficient catalysts for PDH is of great significance for the industry. Herein, the paper reports that a catalyst with potassium-promoted Pt-In bimetallic clusters encapsulated in silicalite-1 (S-1) zeolite works as an efficient and stable catalyst for PDH. The catalyst achieves a propane conversion of 43.73 % with 97.14 % selectivity of propene and an extremely high propylene productivity of 20.33 mol g Pt -1 h -1 with a weight hourly space velocity (WHSV) of 6.75 h −1 . No obvious deactivation occurs after 48 h on stream, affording an extremely low deactivation constant of 0.0025 h −1 . The introduction of indium species greatly improves the propene selectivity and restricts the coke formation. The introduction of K + into S-1 can significantly enhance the catalytic activity and the stability of the catalyst. The catalyst with excellent activity and stability is potential for industrial application.
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Frontiers in Marine Science
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2022
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IF 5.247
Wang Jingjing,Li Xiuying,Yan Jun,Yang Yi
Microbial reductive dechlorination has been considered an effective process for the clean-up of organohalide-contaminated sites. Heavy metal ions are commonly present as co-contaminants in various organohalide-contaminated sites. To understand the impacts of heavy metal ions on the environmental fate of organohalides, we investigated the effects of Zn2+, Cu2+ and Cd2+ on reductive dechlorination of tetrachloroethene (PCE) and 1,2-dichloroethane (1,2-DCA) in sediment microcosms and transferred enrichment cultures. PCE and 1,2-DCA-dechlorinating enrichment cultures could be consecutively transferred in the presence of up to 10 mg/L Cu2+ or 10 mg/L Zn2+; by comparison, up to 50 mg/L Cd2+ had minor impacts on the microbial reductive dechlorination of PCE and 1,2-DCA. The inhibitory effects of tested heavy metal ions on microbial reductive dechlorination ranked in descending order are Zn2+, Cu2+, and Cd2+. Community profiling and principal component analysis indicate that the concentration and type of contaminants (e.g., heavy metal ions, organohalides) shaped the microbial community structure, an observation similar to a prior report. The enrichment of certain organohalide-respring bacteria (e.g., Dehalococcoides, Dehalogenimonas) during continuous transfers exposed to heavy metal ions suggests that they are capable of tolerating high concentrations of heavy metal ions. Our findings provide insights into the impacts of heavy metal ions on microbial reductive dechlorination and may be helpful for in situ bioremediation at sites contaminated with organohalides and heavy metals.
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ANALYTICA CHIMICA ACTA
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2022
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IF 6.911
Xiaofen Zhao,Xiaoxiao Tian,Yuwei Wang,Linbin Li,Yan Yu,Shiqiao Zhao,Juan Zhang
Accurate analysis of HIV DNA is valuable for the diagnosis of AIDS. Herein, an ultrasensitive and specific fluorescence method was developed for HIV-1 DNA detection based on CRISPR-Cas12a-activated palindrome-catalytic hairpin assembly (CRISPR-Cas12a-PCHA). The presence of HIV-1 DNA activated the trans-cleavage activity of CRISPR-Cas12a, which could continuously digest the DNA fragment of hairpins connected to magnetic beads to expose single-stranded RNA . After magnetic separation, the exposed RNA triggered multiple PCHA reactions, generating many Y-shaped DNA structures that were self-assembled into the DNA superstructures via the hybridization of palindromic sticky ends, leading to the release of amounts of fluorescence signal. Different from the reported recently biosensing strategies of nucleic acid amplification technologies-activated CRISPR-Cas12a, CRISPR-Cas12a-PCHA endowed the strategy with unique advantages of simple sample pretreatment , direct duplex target detection, and ultrahigh sensitivity. The strategy was able to resist the interference of the complex matrix in real sample and distinguish between HIV patients and healthy persons. Thus, the method is a promising tool for ultrasensitive and specific detection of HIV-1 DNA for AIDS diagnosis.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
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2022
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IF 3.898
Shiyong Xing,Yan Cui,Tiefeng Wang,Jinwei He,Minghan Han
In the present work, the effect of oxides on the alkylation of benzene with 1-dodecene was comprehensively investigated over MCM-49 n -heptanol, n -heptaldehyde and n -heptanoic acid were selected as the model oxides herein, and obvious decrease of lifetime could be caused by only trace amount of oxides added in the feedstocks. However, the deactivated catalysts were difficult to be regenerated by extraction with hot benzene. Additionally, coke-burning was also proved to be incapable to regenerate the deactivated catalysts mainly for the dealumination during calcination . Further characterizations complementary with DFT calculations were conducted to demonstrate that the deactivation was mainly due to the firm adsorption of oxides on the acid sites.
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Microbiology Spectrum
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2022
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IF 9.043
Lujun Yin,Ping-Ping Zhang,Wei Wang,Shi Tang,Shi-Ming Deng,Ai-Qun Jia
Serratia marcescens (S. marcescens) is an environmental bacterium that causes infections with high morbidity and mortality. Notably, infections caused by multidrug-resistant S. marcescens have become a global public health issue. Therefore, the discovery of promising compounds to reduce the virulence of pathogens and restore antibiotic activity against multidrug-resistant bacteria is critical. Quorum sensing (QS) regulates virulence factors and biofilm formation of microorganisms to increase their pathogenicity and is, therefore, an important factor in the formation of multidrug resistance. In this study, we found that 3-phenylpropan-1-amine (3-PPA) inhibited S. marcescens NJ01 biofilm formation and virulence factors, including prodigiosin, protease, lipase, hemolysin, and swimming. The combination of 3-PPA (50.0 μg/mL) and ofloxacin (0.2 μg/mL) enhanced S. marcescens NJ01 sensitivity to ofloxacin. Based on crystalline violet staining, scanning electron microscopy (SEM), and confocal laser scanning microscopy (CLSM), 3-PPA (50.0 μg/mL) reduced S. marcescens NJ01 biofilm formation by 48%. Quantitative real-time PCR (qRT-PCR) showed that 3-PPA regulated the expression of virulence- and biofilm-related genes fimA, fimC, bsmB, pigP, flhC, flhD, and sodB. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) indicated that 3-PPA affected intracellular metabolites of S. marcescens NJ01, leading to reduce metabolic activity. These results suggested that 3-PPA inhibits the pathogenicity of S. marcescens NJ01 by occluding QS. Thus, 3-PPA is feasible as an ofloxacin adjuvant to overcome multidrug-resistant S. marcescens and improve the treatment of intractable infections.IMPORTANCE Multidrug-resistant bacteria have become a major threat to global public health, leading to increased morbidity, mortality, and health care costs. Bacterial virulence factors and biofilms, which are regulated by quorum sensing (QS), are the primary causes of multidrug resistance. In this study, 3-PPA reduced virulence factors and eliminated biofilm formation by inhibiting QS in S. marcescens NJ01 bacteria, without affecting bacterial growth, thus restoring sensitivity to ofloxacin. Thus, the discovery of compounds that can restore antibiotic activity against bacteria is a promising strategy to mitigate multidrug resistance in pathogens.
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Journal of Functional Foods
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2022
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IF 5.223
Jinyuan Wang,Yinyan Yin,Nuo Xu,Bangyue Zhou,Tao Qin
In the bacterial infection of humans, sepsis is of great concern based on its high fatality rate. Correction of immune dysfunction by targeting dendritic cells (DCs) is a promising strategy for sepsis therapy. Royal jelly, a natural health product, is produced by worker bees for feeding queens. In the study, we evaluated whether royal jelly could attenuate LPS-induced immune dysfunction of DCs. We found that royal jelly reduced the expression levels of mature phenotype (MHCII, CD40, CD80, and CD86), activation marker (CD69), and inflammatory cytokines (TNF-α, IL-6, and IL-10) in LPS-induced DCs. In addition, royal jelly enhanced the endocytosis levels and abrogated allogeneic CD4 + T cell proliferation in LPS-induced DCs. Finally, we found that the Nrf2/HO-1 axis played a vital role in the inhibition of LPS-induced immune dysfunction of DCs by royal jelly. These results indicated that royal jelly had a potential application in sepsis therapy by regulating DC function.
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Drug Design Development and Therapy
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2022
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IF 4.319
Deshan Yao,Bo Shi,Sichuan Wang,Liuxiang Bao,Meng Tan,Hui Shen,Zhengang Zhang,Xin Pan,Yi Yang,Yong Wu,Kaizheng Gong
Background Oxidative stress and inflammatory reaction play critical roles in acute myocardial infarction (AMI). Isoliquiritigenin (ISL), a flavonoid monomer extracted from licorice, has been found to have antioxidant and anti-inflammatory effects in cancer studies. Here, we tested the effect and underlying mechanisms of ISL on ischemia-induced myocardial injury in a mouse AMI model. Methods Adult C57BL/6 mice were pre-treated by intraperitoneal injection of ISL and/or a specific nuclear factor E2-related factor 2 (Nrf2) inhibitor ML385 for 3 days, respectively. Then, the AMI model was established by ligating the anterior descending branch of the left coronary artery. Myocardial oxidative stress status, inflammatory response, cardiac function and infarction size were assessed after 7th day of surgery. Results Compared with sham group, the reactive oxygen species (ROS) and malondialdehyde (MDA) level in AMI group were significantly increased. However, the superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) level were dramatically decreased. ISL treatment significantly reduced the myocardial infarction area, improved cardiac function, inhibited the production of ROS and MDA and reduced the consumption of SOD and GSH-Px. Interestingly, ISL could significantly increase nuclear Nrf2 and cytosolic heme oxygenase 1 (HO-1) level in the infarcted myocardium and reduce the oxidative stress after AMI. Also, ISL treatment dramatically inhibited the activation of myocardial NF-κB pathway and reduced the expression of pro-inflammatory factors in the AMI group. However, the administration of ML385 not only suppressed the Nrf2/HO-1 activation, the anti-oxidant and anti-inflammatory effects induced by ISL, but also attenuated the beneficial role of ISL on reducing infarct size and improving cardiac function in the mouse with AMI. Conclusion The results suggested that activation of Nrf2/HO-1 pathway has an essential role in ISL-induced cardiac protection by alleviating myocardial oxidative stress and inflammation response in mice with AMI.
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MICROPOROUS AND MESOPOROUS MATERIALS
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2022
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IF 5.876
Pengyu Zhao,Zhiguang Li,Yue Zhang,Debao Cui,Qingchun Guo,Zhipeng Dong,Guodong Qi,Jun Xu,Feng Deng
One-step direct hydroxylation of aromatics is an atom-economic way for phenols production. Ti-containing MFI zeolite is considered to be one of the most potential catalysts for hydroxylation of aromatics to phenols under mild condition with aqueous H 2 O 2 as the oxidant. However, the products are often a mixture of mono- or multi-phenols. Designing TS-1 zeolite catalyst with high yield and selectivity to the target phenols remains a challenging task. Here TS-1 zeolites are prepared by direct hydrothermal and post-synthetic methods. Multiple spectroscopic characterizations show that the crystallinity and Ti-Lewis acid sites (Ti-LASs) distribution of TS-1 zeolite can be controlled by the synthetic approach. The structure-activity relationship of TS-1 zeolite is established in the catalytic hydroxylation of anisole, revealing that Ti-LASs concentration determines the conversion of anisole, while both the crystallinity and Ti-LASs distribution significantly influence the selectivity to the desired product para -hydroxyanisole.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2022
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IF 10.319
Long Sun,Lingling Li,Jiajie Fan,Quanlong Xu,Dekun Ma
The rapid charge recombination and low surface reaction kinetics are the two major constraints to the photocatalytic performance of covalent organic frameworks (COFs). To accelerate the charge separation behavior, TpPa-1-COF is decorated with WO 3 via an in-situ growth approach, and the resultant WO 3 /TpPa-1-COF composites show significantly improved photocatalytic performance. Especially, when the WO 3 loading arrives at 3 wt%, 3%WO 3 /TpPa-1-COF exhibits the maximum photocatalytic H 2 evolution rate of 19.89 mmol g −1 h −1 , which is approximately 4.8 times higher than that of pure TpPa-1-COF. The apparent quantum efficiency (AQE) of 3%WO 3 /TpPa-1-COF at 420 nm is detected to be 12.4%. X-ray photoelectron spectroscopy (XPS) characterization confirms the formation of internal electric field between WO 3 and TpPa-1-CF, which can drive the photogenerated charge carrier diffusion in S-scheme mode. As a result, WO 3 /TpPa-1-COF composite possesses high charge separation efficiency and strong redox ability, which is further supported by the photoelectrochemical results, thus benefiting the photocatalysis process. This work provides a rational strategy to modify COFs in photocatalytic water splitting.
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POLYMER
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2022
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IF 4.432
Yuxin Zhang,Kunmei Su,Maliang Zhang,Zhenhuan Li
In order to improve the permeability and desalination performance of the thin-film nanocomposite (TFN) membranes supported by polyphenylene sulfide ( PPS ), the polydopamine (PDA) modified HKUST-1 (mHKUST-1) nanocomposite materials were added into polyamide ( PA ) functional layer. The mHKUST-1 nanoparticles with good dispersity and chemical compatibility were successfully embedded in PA layer to develop a new negative charged nanofiltration membrane . The optimized PPS/ [email protected] membrane showed an excellent permeability of up to 27.35 L∙m −2 h −1 ∙bar −1 , twice as much as the [email protected] membranes. Meanwhile, the considerable rejection performance of 91.67% to MgSO 4 and 90.06% to Na 2 SO 4 at 4 bar was mainly up to the repulsive effect of negative charge on membrane surface. Moreover, the PPS/ [email protected] membranes also has stable filtration performance under long time operation. The results suggested that the membrane modification method in this work have great potential for applications in desalination.
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ACS Sustainable Chemistry & Engineering
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2022
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IF 9.224
Wenya Chen,Qingyun He,Ziyao He,Qin Wang,Jing Ding,Qiao Huang,Xiaojuan Liang,Zhaoping Chen,Weidong Xiang
In recent years, all-inorganic metal lead halide cesium perovskites (CsPbX3, X = Cl, Br, and I) have shown excellent luminescence performance in the field of wide color gamut backlight displays. However, Pb2+ in CsPbX3 easily leaks because of the unstable structure of CsPbX3, which seriously threatens human health. However, Mn-based metal halides (MHs) have unique environmentally friendly characteristics. In this work, Zn2+-doped Cs3MnBr5 MHs were successfully prepared, which exhibited highly efficient green emissions at 520–522 nm. Moreover, Cs3MnxZn(1–x)Br5 shows excellent stability at room temperature (25 °C) compared with Cs3MnBr5. More excitingly, when Cs3MnxZn(1–x)Br5 was encapsulated in a polystyrene (PS) polymer, Cs3MnxZn(1–x)Br5@PS showed better water, acid, daylight, and blue light stabilities. In addition, the backlight display device was designed based on different green–red ratios and thicknesses of Cs3MnxZn(1–x)Br5@K2SiF6:Mn4+@PS light conversion films, and the color gamut was over 109% of the NTSC 1953 standard, which is better than that of the reported WLED devices based on Mn-based MHs thus far. This work undoubtedly shows that Mn-based MHs have great application potential in wide color gamut backlight displays and provide a practicable route to fabricate nontoxic, low-cost, and high-performance liquid crystal displays.
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