RSC Advances
·
2020
·Vol. 10
·期 47
·28408-28414
·
IF 3.119
Heming Zheng,Bo Duan,Zheyu Xie,Jie Wang,Mingying Yang
Bombyx mori (B. mori) silk fibroin (SF) microcapsules have acted as a great candidate in delivering drugs. However, it is difficult to fabricate SF nanocapsules using the present layer-by-layer (LBL) technique. In addition, the current SF microcapsules have limits in loading negatively charged drugs. Here, we invent a novel LBL method by introducing silane (APTES) as a structure indicator to produce SF nanocapsules that can load drugs with negative or positive charge. LBL assembly was completed by alternately coating SF and APTES on the template of polystyrene (PS) nanospheres by electrostatic attraction. SF nanocapsules were obtained after removal of the PS templates. Zeta potential analysis proved LBL assembly was indeed driven by the interaction between negative charge of SF and positive charge of APTES. Fluorescence images and electric microscope images indicated that SF nanocapsules had a hollow and stable structure with diameter at nearly 250 nm. The highest encapsulation rate of DOX or Ce6 were up to 80% and 90%, respectively, indicating SF nanocapsules have a high loading capability for both cationic and anionic drugs. In vitro cell experiments proved the biocompatibility of SF nanocapsules and their burst drug release in response to acidic environment. Furthermore, chemotherapy and photodynamic therapy proved SF nanocapsules loaded with DOX or Ce6 had significant inhibition on tumor cells. Our results suggested that this LBL technique is a facile method for polymers with negative charge to fabricate nanocapsules for antitumor drug carrier.
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JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
·
2019
·
IF 2.983
Baofang Zhang,Zilin Chen
A simple and valid method for rapid screening of cathepsin B inhibitors from traditional Chinese medicines (TCMs) was established by the combination of immobilized enzyme microreactor (IMER) and capillary electrophoresis. Cathepsin B was immobilized on the inner surface of the capillary by glutaraldehyde method. The separation of substrate and product could be finished by baseline within 3 min. The activity of the immobilized cathepsin B remained approximately 90% after 50 runs. The quantification and statistical analysis of the product peak area was used to evaluate the catalytic activity of cathepsin B. The value of Michaelis-Menten constant of cathepsin B was 0.85 mM. The half-maximal inhibitory concentration (IC 50 ) of L -trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) was measured as 36.08 nM, which indicated that the cathepsin B reactor was successfully developed and was feasible for inhibitorscreening. The raised method was then applied to discover the inhibitory potential of 17 standard compounds from traditional Chinese medicines. Five natural products, including kaempferol, rutaecarpine, evodiamine, theophylline, lycobetaine showed potential inhibition for cathepsin B. Additionally, molecular docking study was investigated for supporting the interaction between enzyme and inhibitors.
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PubMed
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APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Nan Zhou,Yufan Wu,Qing Zhou,Yiran Li,Shihan Liu,Hongbo Zhang,Zhi Zhou,Mao Xia
Silicon monoxide (SiO) is regarded as a great potential anode material for high-energy lithium-ion batteries (LIBs) owing to the high theoretical specific capacity (2650 mAh g −1 ), low voltage platform, eco-friendly and rich reserves. However, the particle pulverization , induced by large volume change during (de)lithiation, can result in the capacity degrading significantly. As we all know, it is a good strategy that using TiO 2 to modify the SiO-based anode. TiO 2 can serve as rigid outer layer to keep the structural integrity. In addition, the electrochemical performances of monoclinic TiO 2 (B) are better than anatase and rutile TiO 2 . Therefore, compositing with TiO 2 (B) is an admissible method to enhance the electrochemical properties of SiO-based materials. And the pretreated-SiO/TiO 2 (B) composites (abbreviated as p-STB) are prepared by hydrothermal treatment at 180 °C for 12 h and then calcined at 325 °C for 2 h. In this paper, p-STB-1 and p-STB-2 are prepared that the weight ratios p-SiO and TiO 2 (B) are 4:1 and 3:1, respectively. The structure and components of composites are also performed on X-ray diffraction (XRD), Fourier transform infrared reflectance (FT-IR) spectroscopy, scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). For p-STB, TiO 2 (B) is mainly covered on the surface of pretreated SiO (p-SiO). The Li-ion diffusion coefficients of as-prepared materials are calculated by cyclic voltammetry and electrochemical impedance spectroscopy . The electrochemical test results suggest that the p-STB-1 has batter cycling performance (730 mAh g −1 after 100th cycle) and admirable rate capacity (450 mAh g −1 under 3.2 A g −1 ). The modified method, which was compositing with TiO 2 (B), is beneficial to the commercialization of SiO-based materials.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2021
·
IF 4.464
Mingguang Ma,Jing Lu,Ling Wang,Xia Qiu,Tingting Xu,Sufan Wang,Yinggui Zhu
In this work, we first reported the electrochemiluminescence (ECL) properties of 2-hydroxynicotinic acid (2-HNA) with 0.09 M K 2 S 2 O 8 in 0.5 M H 3 BO 3 – Na 2 B 4 O 7 buffer solution. The effects of the type of co-reactant, the concentration of K 2 S 2 O 8 and the pH of the buffer solution on the ECL intensity of this system were investigated. And the possible mechanism of 2-HNA/ K 2 S 2 O 8 system has been speculated by fluorescence spectrum and ECL spectrum. Besides, we found that phloxine B (PB) can significantly enhance the ECL intensity of the 2-HNA/ K 2 S 2 O 8 system. It is speculated that an electrochemiluminescence resonance energy transfer (ECL-RET) process may occur between 2-HNA and PB, so that PB enhanced the ECL of the 2-HNA system. Combining the ultraviolet spectrum and density functional theory (DFT) calculations further proved the rationality of this speculation. Based on this, a new method of ECL detection of PB with high sensitivity and high selectivity was established.
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Journal of Materiomics
·
2020
·
IF 5.797
Wenjie He,Tengfei Zhang,Zhiwei Li,Jiangmin Jiang,Chenglong Chen,Nan Liu,Hui Dou,Xiao Gang Zhang
Currently, the practical application of SiO x still has a huge hindrance in the area of lithium ion battery, because it is unable to achieve an effective contact with surrounding conducting materials, resulting in failure to form lithium ion migration tunnels. In this work, we presented a facile method to synthesize the B-doped SiO x composite by adhering SiO x particles with MWCNT (multi-walled carbon nanotube) under the assistance of lithium metaborate (LiBO 2 ). LiBO 2 , as a sintering aid, not only can react with SiO x to form a compacted framework, but also build a three-dimensional (3D) conductive network for ions transportation. Furthermore, B-SiO x @CNT@LBO anode delivers a remarkable lithium storage performance in terms of long cycles and high rate capability. A full cell coupled with NCM622 cathode achieves a high energy density of 429.5 Wh kg −1 based on the total mass of cathode.
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高影响因子
Science of Advanced Materials
·
2019
·Vol. 11
·期 3
·418-424
·
IF 1.158
Lv Yao,Huang Shifei,Zhao Yufeng
The N-B-F tridoping 3D hierarchical porous graphitized carbon network is produced by a one-step synthesis using chitosan as a precursor. The N-B-F tridoping 3D hierarchical porous graphitized carbon network is rich of nitrogen, boron and fluorine hetero atoms and exhibited relatively
high specific capacitance value of 316 F g–1 in 6 M KOH at a current density of 20.0 A g–1. As well as good cycling stability with capacitance retention of 100% over 10000 cycles, and good rate performance (90.3% capacity retention from 0.5 A g–1
to 20.0 A g–1). When used as supercapacitor electrode, the all carbon symmetric supercapacitor based on N-B-F tridoping 3D hierarchical porous graphitized carbon network delivers a high energy density of 23.87 Wh kg–1, outperforming the state-of-the-art carbon
material.
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高影响因子
Journal of Food Measurement and Characterization
·
2021
·Vol. 15
·期 5
·4021-4029
·
IF 2.431
Xie Li,Li Chen,Deng Guozhe,Li Da,Kang Xuejun
This paper reported a simple, sensitive and environmental-friendly packed nanofiber-based solid phase extraction (PFSPE) technique for the extraction of eight water-soluble B-complex vitamins from infant formula products. The developed PFSPE technique used core/sheath polystyrene/polypyrrole (PS/PPy) nanofibers as adsorbents, and the process involved boric acid compound as complexing reagent which formed conjugated compounds with targets. The PS/PPy nanofibers were prepared in situ polymerization of PPy on the surface of PS nanofibers fabricated by electrospinning. Pretreated samples were analyzed with High Performance Liquid Chromatography coupled with UV Detector system (HPLC–UV). Method validation obtained the intra- precision at 0.6–17.1% and inter-day precision at 0.9–18.2%, respectively, the limits of detection between 0.25 and 0.9 μg g −1 , and the linear range of the calibration curves at 0.25–250 μg g −1 , and relative recoveries from 76.3 to 126.0%.
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CONSTRUCTION AND BUILDING MATERIALS
·
2020
·
IF 4.419
Dan Wang,Pengkun Hou,Dietmar Stephan,Shifeng Huang,Lina Zhang,Ping Yang,Xin Cheng
For surface functionalization of cement-based materials with photocatalytic properties, weak adhesion between photocatalysis and matrix worsens these properties and results in poor weathering resistance in outdoor environments. To overcome these problems, in this study, two SiO 2 /TiO 2 composites, with different deposited densities of TiO 2 nanoparticles on a SiO 2 sphere, were prepared and used for surface coating of cement-based materials. The two composites show different efficiencies. The photocatalytic results show that the coated cement pastes exhibited excellent rhodamine B-removal efficiency before and after curing and accelerated weathering processes, indicating that SiO 2 in the system has a crucial effect as a ‘glue’ preventing the release of TiO 2 . The bonding mechanism was revealed by the reaction of the samples and main components and hydration products (such as CH, C-S-H and C 3 S).
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高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2017
·
IF 3.648
Dun Fu,Yujia Huang,Xueting Zhang,Tonni Agustiono Kurniawan,Tong Ouyang
This study investigates the impacts of hydrogen peroxide (H 2 O 2 ) addition on the removal of tetracycline (TC) from aqueous solution by TiO 2 (B) nanosheets (NSs) and compares the changes of its characteristics due to adsorption treatment. The morphology and textural properties of the TiO 2 (B) NSs structure before and after the treatment were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). Effects of pertinent parameters such as dose of TiO 2 (B) and/or H 2 O 2 concentration, initial adsorbate concentration, pH, and temperature on the TC adsorption by TiO 2 (B) NSs were examined. The adsorption mechanisms of TC by the integrated treatment of TiO 2 (B) NSs and H 2 O 2 are also presented. The results demonstrated that the integrated treatment of TiO 2 (B)-H 2 O 2 system had significantly improved the TC removal by 250% (with its adsorption capacity ( q max ) of 212.77 mg g − 1 ), as compared to that of the TiO 2 -H 2 O 2 system (paired t-test ; p ≤ 0.05) under the same optimum conditions (2 g L − 1 of TiO 2 (B) NSs; 20 mM of H 2 O 2 ; 0.1 g L − 1 of initial TC concentration). The enhanced TC adsorption by the integrated TiO 2 (B)-H 2 O 2 system not only is due to the H-bonding between the TC molecules and the –OOH groups formed on TiO 2 (B) surface, but it is also because of electrostatic interactions. Their adsorption isotherms followed the Elovich model and were also applicable to both the Langmuir and the Freundlich models. In spite of the adsorbent's promising performance, its treated effluents still could not meet the required TC effluent limit of < 62.5 μg L − 1 . This suggests that further subsequent treatment like biological processes is still necessary to completely remove the target pollutant from the wastewater samples.
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高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2018
·Vol. 18
·期 12
·8337-8344
·
IF 1.354
Guo Min,Yang Lu,Chen Jia,Zhang Jun,Su Haijun,Liu Lin,Xie Keyu
The relatively small electron diffusion coefficient and high charge recombination rate of TiO2 nanoparticle (NP) film limit charge collection in TiO2 NP based dye-sensitized solar cells (DSSCs). Herein, ultralong bending TiO2 (B) nanowires (NWs) were
introduced to TiO2 NP photoanode and expected to modify electron transport of DSSCs. The TiO2 (B) NWs/TiO2 NP composite structure was prepared by a facial process combining the stirring hydrothermal method with mechanical mixing method. When the composite structure
was applied to DSSCs, the rapid electron transport pathway was formed in photoanode, which was clarified by the small electron transport resistance and long electron diffusion length, improving the charge collection efficiency. Moreover, the scattering effect of TiO2 (B) NWs could
enhance the light harvesting, and thus improve the power conversion efficiency (PCE) of DSSCs. The excellent electronic and optical characteristics of TiO2 (B) NWs yield the maximum enhancement of PCE (36.4%) when 50% (wt.%) TiO2 (B) NWs was integrated into TiO2
NP based DSSC. The work provides new insights into the design and tailoring nanowires to enhance the PCE of DSSCs for practical applications.
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Nanoscale
·
2015
·Vol. 7
·期 28
·12215-12224
·
IF 7.394
Yongquan Zhang,Qiang Fu,Qiaoling Xu,Xiao Yan,Rongyu Zhang,Zhendong Guo,Fei Du,Yingjin Wei,Dong Zhang,Gang Chen
N-doped TiO2-B nanowires are prepared by the solvothermal method using TiN nanoparticles as the starting material. X-ray photoelectron spectroscopy shows that the N dopants preferentially occupy the interstitial sites of TiO2-B up to a content of ∼0.55 at%. Above this critical value, the N dopants will substitute the oxygen atoms which improve the electronic conductivity of TiO2-B. The maximum proportion of substituted-N in the TiO2-B nanowires is ∼1.3 at%. Raman scattering shows that the substituted-N strengthens the Ti(1)–O1–Ti(2) and O1–Ti(1)–O3 bonds of TiO2-B. This improves the stability of the corresponding local structures, thus reducing the distortion of the Li+ diffusion channel along the b-axis of TiO2-B. As a result, the substituted-N has more of an impact on the electrochemical properties of TiO2-B than the interstitial-N does. The TiO2-B nanowires containing substituted-N dopants exhibit a remarkably enhanced electrochemical performance compared to pure TiO2-B. They show a discharge capacity of 153 mA h g−1 at the 20 C rate with a capacity retention of 76% after 1000 cycles. In addition, they can deliver a discharge capacity of 100 mA h g−1 at an ultra-high rate of 100 C, indicating their great potential in high power lithium ion batteries.
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RSC Advances
·
2025
·Vol. 15
·期 16
·12629-12644
·
IF 4.6
Yinqi Yang,Guoshuai Ma,Xiaoli Hu,Wei Wang,Zhonglin Du,Yao Wang,Xue-zhong Gong,Haoyu Tan,Fengxiang Guo,Jianguo Tang
In the context of sustainable development, the utilization of semiconductor materials for the degradation of dyes, antibiotics, heavy metals, and pesticides in wastewater under visible light has emerged as a focal point of contemporary research. In this investigation, a WO3@TiO2 composite was synthesized via a solvothermal method, with the composite exhibiting a molar ratio of 5% WO3 to TiO2 precursors demonstrating optimal photocatalytic degradation performance. This material achieved complete degradation of 20 mg per L Rhodamine B (RhB) dye and tetracycline (TC) antibiotic within 30 min. Furthermore, the effects of initial pollutant concentration and solution pH on catalytic efficacy were systematically explored. The findings revealed that at RhB concentrations below 40 mg L−1, the degradation proceeded at an accelerated rate, with a rate constant exceeding 0.128 min−1. The catalyst exhibited robust performance across a broad pH range, attaining peak degradation efficiency at pH ≈ 3. The exceptional photocatalytic prowess of the WO3@TiO2 composite is predominantly attributable to its distinctive hollow microstructure, the intimate interfacial synergy between WO3 and TiO2, and the efficient separation of photogenerated electrons and holes facilitated by the type-II heterojunction architecture.
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