ACS Applied Energy Materials
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2023
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IF 6.4
Yahong Xie,Ke Zhao,Haobin Wang,Ying Qi,Peng Wei,Jian Cheng
SnO2 is considered as a promising electron transport material for carbon-based perovskite solar cells (C-PSCs) due to its excellent electron mobility, stability over TiO2, and low-temperature processing. However, the lattice mismatch and poor contact quality of the SnO2/CH3NH3PbI3 interface, as well as oxygen vacancies, usually lead to nonradiative recombination and limit the further improvement of photovoltaic performance. In this paper, two chitosan derivatives, chitosan quaternary ammonium salt (HACC) and carboxymethyl chitosan (CMCS), were used as additives for SnO2 to adjust the energy level and improve the contact performance of the SnO2/CH3NH3PbI3 interface. These two additives have suitable terminal active functional groups, amino group and hydroxyl group, which can interact with SnO2 and CH3NH3PbI3 at the interface, induce the crystal growth of the perovskite, and play a good role in passivating interfacial defects. Therefore, the interfacial contact and the charge-transfer ability were effectively enhanced. As a result, the addition of HACC and CMCS increased the PCE of C-PSCs from 10.17 to 12.42 and 13.39%, and the repeatability and long-term stability of the corresponding unencapsulated C-PSCs were also significantly improved. This work expands the vision for the future interface modification strategies to improve the device performance and is conducive to promote the further commercialization of C-PSCs.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Ying Li,Xiu-Er Luo,Ming-Jun Tan,Fu-Hao Yue,Run-Yu Yao,Xin-An Zeng,Meng-Wai Woo,Qing-Hui Wen,Zhong Han
In this study, a novel carboxymethylcellulose / ZnO / chitosan (CMC / ZnO / Cs) hydrogel microbeads loaded with crosslinked porous starch / curcumin (CPS / Cur) were designed and prepared to improve the encapsulation efficiency of curcumin for drug delivery to specific sites. It was found that the total pore volume of crosslinked porous starch (CPS) was increased by 1150 % when compared to the native starch (NS), and the adsorption ratio of curcumin by CPS was enhanced by 27 % when compared to NS. Secondly, the swelling ratio of composite hydrogel microbeads was within 25 % in an acidic environment at pH 1.2, and the swelling ratio of hydrogel microbeads sharply increased to 320 % ~ 370 % at pH 6.8 and 7.4. In addition, the results of in vitro simulated release experiments showed that the released amount of hydrogel microbeads loaded with NS/Cur and CPS/Cur in SGF were within 7 % in simulated gastric fluid (SGF). The highest released amount of curcumin was 65.26 % for hydrogel beads loaded with CPS/Cur, which was 26 % lower than that of hydrogel microbeads loaded with Cur in simulated intestinal fluid (SIF). In simulated colonic fluid (SCF), the released amount of hydrogel microbeads loaded with CPS/Cur and Cur were 73.96 % and 91.69 %, respectively. In conclusion, pH-sensitive drug delivery system with good drug stability and bioavailability were successfully prepared with carboxymethylcellulose / ZnO / chitosan bead, suitable targeting drug delivery to the small intestine .
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Jia Wan,Yongzhi Liang,Xiaofeng Wei,Haiyi Liang,Xu-Lin Chen
Skin injuries are one of the most common clinical traumas worldwide, and wound dressings are considered to be one of key factors in wound healing. Natural polymer-based hydrogels have been developed as ideal materials for a new generation of dressings due to their excellent biocompatibility and wetting ability. However, the inadequate mechanical performances and lack of efficacy in promoting wound healing have limited the application of natural polymer-based hydrogels as wound dressings. In this work, a double network hydrogel based on natural chitosan molecules was constructed to enhance the mechanical properties, and emodin, a herbal natural product, was loaded into the hydrogel to improve the healing effect of the dressing. The structure of the chitosan–emodin network formed by Schiff base reaction and microcrystalline network of biocompatible polyvinyl alcohol endowed hydrogels with excellent mechanical properties and ensured its integrity as wound dressings. Moreover, the hydrogel showed excellent wound healing properties due to the loading of emodin. The hydrogel dressing could promote cell proliferation, cell migration, and secretion of growth factors. The animal experimental results also demonstrated that the hydrogel dressing facilitated the regeneration of blood vessels and collagen and accelerated wound healing.
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LANGMUIR
·
2023
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IF 3.9
Qianwen Xue,Jiangqin Wu,Zaosheng Lv,Yang Lei,Xuegang Liu,Yanfen Huang
Superhydrophobic cotton fabrics have a lot of potential for use in practical settings. The majority of superhydrophobic cotton fabrics, however, only serve one purpose and are made from fluoride or silane chemicals. Therefore, it remains a challenge to develop multifunctional superhydrophobic cotton fabrics using environmentally friendly raw materials. In this study, chitosan (CS), amino carbon nanotubes (ACNTs), and octadecylamine (ODA) were used as raw materials to create CS-ACNTs-ODA photothermal superhydrophobic cotton fabrics. The cotton fabric that was created showed a remarkable superhydrophobic property with a water contact angle of 160.3°. The surface temperature of CS-ACNTs-ODA cotton fabric can rise by up to 70 °C when exposed to simulated sunlight, demonstrating the fabric’s remarkable photothermal capabilities. Additionally, the coated cotton fabric is capable of quick deicing. Ice particles (10 μL) melted and began to roll down in 180 s under the light of “1 sun”. The cotton fabric exhibits good durability and adaptability in terms of mechanical qualities and washing tests. Moreover, the CS-ACNTs-ODA cotton fabric displays a separation efficacy of more than 91% when used to treat various oil and water mixtures. We also impregnate the coating on polyurethane sponges, which can quickly absorb and separate oil and water mixtures.
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Materials Today Bio
·
2023
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IF 8.2
Lin Huang,Wantao Wang,Yiwen Xian,Lei Liu,Jinghao Fan,Hongmei Liu,Zhaomin Zheng,Decheng Wu
Intervertebral disc (IVD) degeneration occurred with the increasing age or accidents has puzzled peoples in daily life. To seal IVD defect by injectable hydrogels is a promising method for slowing down IVD degeneration. Herein, we reported a rapidly in situ forming injectable chitosan/PEG hydrogel (CSMA-PEGDA-L) through integrating photo-crosslink of methacrylate chitosan (CSMA) with Schiff base reaction between CSMA and aldehyde polyethylene glycol (PEGDA). The CSMA-PEGDA-L possessed a stronger compressive strength than the photo-crosslinked CSMA-L hydrogel and Schiff-base-crosslinked CSMA-PEGDA hydrogel. This chitosan/PEG hydrogel showed low cytotoxicity from incubation experiments of nucleus pulpous cells. When implanted on the punctured IVD of rat's tail, the CSMA-PEGDA-L hydrogel could well retard the progression of IVD degeneration through physical plugging, powerfully proven by radiological and histological evaluations. This work demonstrated the strategy of in situ injectable glue may be a potential solution for prevention of IVD degeneration.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Wenjie Ye,Jianfeng Xi,Yan Sun,Liucheng Meng,Huiyang Bian,Huining Xiao,Weibing Wu
Elastic and hydrophobic aerogels have received a lot of attention in dealing with the increasing oil pollution due to their recyclable properties. Herein, we present an ultralight and superelastic aerogel with highly oriented polygon structure based on chitin nanofibril (ChNF) and chitosan (CS) by directional freezing. The chemical cross-linking enables good mechanical strength at low aerogel density. After 500 compression-release cycles, the aerogel can retain the deformation recovery rate of 88 % in air, demonstrating the excellent resilience. The bio-based aerogel has high absorption capacity (52-114 g/g) for various oils and organic solvents , and it is able to achieve the absorption retention of 90 % even after 20 absorption-extrusion cycles. Moreover, owing to the good elasticity, the pore size of the aerogel can be adjusted by compression to selectively separate water-in-oil emulsions of different particle sizes with separation efficiencies higher than 99.5 %. The bio-based aerogel with good cycle performance has broad application prospects in the field of oil-water separation.
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CARBOHYDRATE POLYMERS
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2023
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IF 11.2
Sizhao Zhang,Yanrong Liao,Kunming Lu,Zhao Wang,Jing Wang,Linzhe Lai,Wangwang Xin,Yunyun Xiao,Shixian Xiong,Feng Ding
Chitosan aerogels could be applied potentially in thermal insulation for energy-saving buildings, separation/adsorption, and catalysis. However, disadvantages of chitosan aerogels include their hydrophilicity and low insufficient mechanical strength. Here we propose a silica-phase hybriding route to create chitosan/silica hybrid aerogels with a synergistic capability for favourable hydrophobicity and superior mechanical strength, demonstrating an emergent finding (hydrophobicity optimised with the improved mechanical strength). The aerogels exhibit low drying shrinkage (as low as 13.41 %), lightweight (lowest to 0.149 g cm −1 ), high-efficient thermal insulation (thermal conductivity as low as to 0.024 W m −1 K −1 at room temperature and normal pressure) either under cryogenic (−196 °C) or high-temperature conditions, exceptional fire-retardancy (self-extinguishing in 1.8 s) and environmentally friendly characteristic (initial mineralisation after 10 d). High hydrophobic property (water contact angle up to 142°) of the aerogels were achieved depending upon 1H, 1H, 2H, 2H-perfluorodecyltriethoxysilane of vapor deposition, presenting a discovery concerning substantial improvement of mechanical properties (up to 0.188 MPa at 5 % strain, increased by 25 %). Furthermore, we demonstrate that a plausible mechanism for simultaneous hydrophobic and mechanical enhancement is depending upon the modulation of networking skeletons at the nanoscale.
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International Journal of Nanomedicine
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2022
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IF 7.033
Zi Chao Wu,Xin Yu Liu,Jia Yan Liu,Jing Shu Piao,Ming Guan Piao
Aim: Liver fibrosis is mainly characterized by the formation of fibrous scars. Galactosylated chitosan (GC) has gained increasing attention as a liver-targeted drug carrier in recent years. The present study aimed to investigate the availability of betulinic acid-loaded GC nanoparticles (BA-GC-NPs) for liver protection. Covalently-conjugated galactose, recognized by asialoglycoprotein receptors exclusively expressed in hepatocytes, was employed to target the liver.Materials and Methods: Galactose was coupled to chitosan by chemical covalent binding. BA-GC-NPs were synthesized by wrapping BA into NPs via ion-crosslinking method. The potential advantage of BA-GC-NP as a liver-targeting agent in the treatment of liver fibrosis has been demonstrated in vivo and in vitro.Results: BA-GC-NPs with diameters Conclusion: The findings showed that BA-GC-NPs form a safe and effective anti-hepatic fibrosis medication delivery strategy.
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FOOD CHEMISTRY
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2022
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IF 9.231
Chunhua Wu,Zijian Zhi,Mengxia Duan,Jishuang Sun,Haixin Jiang,Jie Pang
To improve the sustainable antibacterial active of nisin, nisin-loaded carboxymethyl chitosan (CMCS-nisin) nanogels (CN NGs) are prepared via a combination method of electrostatic self-assembly and chemical cross-linking. The as-prepared CN NGs are profiled using dynamic light scattering, zeta potential, transmission electron microscopy, fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS). We found CN NGs to be spherical and well dispersed, with an average particle diameter of 45 ± 5.62 nm. Besides, the molecular interactions (electrostatic interactions and hydrogen bonding) between nisin and CMCS are the main driving force in the formation of CN NGs, which is demonstrated by FT-IR, XPS and molecular dynamic simulation analysis. Additionally, the CN NGs showed a great nisin-controlled release behavior and the excellent antimicrobial activity against food-borne bacteria. These results suggested that CN NGs have the potential to be used as a promising bio-preservative in food industry.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Liqiu Chu,Zhiyu Zhou,Zhipan Feng,Xinqi Zhao,Huimin Tan,Yu Chen
To explore a novel solution to the challenges in constructing polymer coated magnetic fluorescent nanoparticles , HTCC/Fe 3 O 4 /CdTe magnetic fluorescent nanoparticles (MFCNPs) that can be well dispersed in water were prepared via the electrostatic interaction of the cationic N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC) and the anion precoated water-soluble cadmium telluride (CdTe) quantum dots (QDs) and the sodium citrate-coated Fe 3 O 4 (SC-Fe 3 O 4 ) magnetic nanoparticles (MNPs), which overcame the performance defects of hydrophobic polymer for surface coating and the possible toxicity of cross-linking agent induced by the hydrophilic polymer coating materials . The structural characterizations by FTIR, XRD and XPS reveal that the surfaces of SC-Fe 3 O 4 MNPs and CdTe QDs are coated with HTCC. TEM imaging suggests that the MFCNPs are spherical particles with the diameters of ∼15–20 nm. The MFCNPs exhibit good biocompatibility. Further investigation suggests that the UV-Vis and fluorescence spectral properties and surface electrical properties of HTCC/Fe 3 O 4 /CdTe MFCNPs are mainly affected by the relative ratios of SC-Fe 3 O 4 MNPs, CdTe QDs and HTCC. The adsorption and release properties of the MFCNPs were studied using bovine serum albumin (BSA) as the model. The results indicate that the chitosan-based magnetic fluorescent composite is a promising delivery carrier candidate with excellent comprehensive properties for both magnetic response and fluorescence imaging.
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CARBOHYDRATE POLYMERS
·
2022
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IF 10.723
Xiaoli Zhang,Qingli Qu,Anquan Yang,Jing Wang,Weixia Cheng,Yankang Deng,Aying Zhou,Tao Lu,Ranhua Xiong,Chaobo Huang
The emergence, spread and difficult removal of bacteria biofilm, represent an ever-increasing persistent infections and medical complications challenge worldwide. Herein, a self-propelled system Prussian blue micromotor (PB MMs) were constructed by gas-shearing technology for efficient degradation of biofilms by combining chemodynamic therapy (CDT) and photothermal therapy (PTT). With the interpenetrating network crosslinked by alginate , chitosan (CS) and metal ions as the substrate, PB was generated and embedded in the micromotor at the same time of crosslinking. The micromotors are more stable and could capture bacteria with the addition of CS. The micromotors show excellent performance, containing photothermal conversion, reactive oxygen species (ROS) generation and bubble produced by catalyzing Fenton reaction for motion, which served as therapeutic agent could chemically kill bacteria and physically destroy biofilm. This research work opens a new path of an innovative strategy to efficiently remove biofilm.
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FOOD HYDROCOLLOIDS
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2022
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IF 11.504
Danmin Yang,Qun Liu,Yahui Gao,Shoumei Wan,Fanrong Meng,Wuyin Weng,Yucang Zhang
Sliver nanoparticles (AgNPs) were loaded on chitosan (CS) and incorporated into polyvinyl alcohol (PVA) to develop novel active food packaging films. AgNPs were fabricated by liquid phase chemical reduction method using CS and sodium citrate friendly reductant of AgNO 3 . The silver we prepared was found to be nanoscale by transmission electron microscopy (TEM) and AgNPs were homogeneously dispersed in the matrix by scanning electron microscopy (SEM). The composite film exhibited excellence mechanical properties with tensile strength of 49.97 MPa and elongation at break of 275.90%. When the concentration of AgNPs was 0.019% (w/w), the diameter of filter paper was 5.00 mm and the inhibition zone against Escherichia coli reached 16.07 mm at 37 °C for 8 h. The water vapor permeability and water solubility of the Ag@CS/PVA films decreased with the incorporation of AgNPs, and this was beneficial for food preservation. Especially, Ag@CS/PVA films could reduce the weight loss of strawberries and avoid microbial infection at 25 ± 1 °C and 50 ± 5% RH. Benefiting for good mechanical properties, antibacterial property, flexibility and high transparency, Ag@CS/PVA films showed its great potential in fruit storage and transportation application.
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