Friction
·
2022
·Vol. 11
·期 6
·911-926
·
IF 4.924
Yu Hongxiang,Chen Haijie,Zheng Zhiwen,Qiao Dan,Feng Dapeng,Gong Zhenbin,Dong Guojun
Nine organic compounds were utilized as model lubricants to investigate the impact of functional groups on tribological performances. Nonanoic Acid with carboxyl showed the best lubrication properties, and fluid film and tribofilm were coexistent in its friction test, bringing a low friction coefficient and wear rate. In addition, the lubricant with low friction coefficient corresponded to high adsorption energy in density functional theory (DFT) calculations. And the lubricant forming adsorption film with large surface energy displayed small wear rate in friction test. Moreover, adsorption energies positively correlated surface energies. Based on the experimental results, the action mechanism of functional groups on tribological properties of lubricants was proposed. Various functional groups make lubricant molecules show different adsorption energies and surface energies. Lubricant molecules with high adsorption energy are more likely to adsorb on substrates and form a vertical monolayer, which can maintain a regular molecular brush structure during friction and bring a low friction coefficient. And lubricant molecules with high surface energy may be more prone having tribochemical reactions during friction and forming protective tribofilm, which leads to a low wear rate.
✓ 已验证
产品关联
DOI
高影响因子
Progress in Biomaterials
·
2022
·Vol. 11
·期 3
·253-261
·
IF 4.878
Lv Yarong,Han Yufen,Yu Zhongxun,Chen Jia,Li Chenxi,Wang Ce,Hu Ping,Liu Yong
Currently, the treatment of burns poses a significant challenge to clinical surgical. The use of nanofibers combined with drugs provides an entirely new option for treating burns. Alum-borneol combination has been shown as a promising alternative in clinical burn treatment. However, the utilization of the alum-borneol combination is not optimistic due to the low solubility of borneol. In this study, alum-borneol incorporated polyvinyl pyrrolidone fibers with a core–shell structure were fabricated through coaxial electrospinning. In vitro Borneol release behavior of fibers with different ratios of alum to borneol was explored. Scanning electron microscopy, transmission electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimeter, in vitro drug release, and in vitro release mechanism were evaluated. The results showed that the fiber membranes maintained an integrated morphology. In vitro dissolution data showed an improved solubility of borneol, which reached more than 82% at 240 min in alum-borneol fibers. It was 4.8 times higher than borneol powder, and the ratio of alum to borneol was 2:1 for the best results. Therefore, alum-borneol incorporated polyvinyl pyrrolidone fibers can significantly improve the dissolution rate of borneol, which opens up a new way for the combined application of the alum and borneol.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACTA PHARMACOLOGICA SINICA
·
2022
·Vol. 44
·期 1
·234-243
·
IF 7.169
Jiang Kai-long,Liu Chang-mei,Nie Li-tong,Jiang Hai-ni,Xu Lei,Zhang Kun-zhi,Fan Li-xia,Gao An-hui,Lin Lu-ling,Wang Xiang-yu,Tan Ming-jia,Zhang Qi-qing,Zhou Yu-bo,Li Jia
Inositol-requiring enzyme 1α (IRE1α) is the most conserved endoplasmic reticulum (ER) stress sensor with two catalytic domains, kinase and RNase, in its cytosolic portion. IRE1α inhibitors have been used to improve existing clinical treatments against various cancers. In this study we identified toxoflavin (TXF) as a new-type potent small molecule IRE1α inhibitor. We used luciferase reporter systems to screen compounds that inhibited the IRE1α-XBP1s signaling pathway. As a result, TXF was found to be the most potent IRE1α RNase inhibitor with an IC 50 value of 0.226 μM. Its inhibitory potencies on IRE1α kinase and RNase were confirmed in a series of cellular and in vitro biochemical assays. Kinetic analysis showed that TXF caused time- and reducing reagent-dependent irreversible inhibition on IRE1α, implying that ROS might participate in the inhibition process. ROS scavengers decreased the inhibition of IRE1α by TXF, confirming that ROS mediated the inhibition process. Mass spectrometry analysis revealed that the thiol groups of four conserved cysteine residues (CYS-605, CYS-630, CYS-715 and CYS-951) in IRE1α were oxidized to sulfonic groups by ROS. In molecular docking experiments we affirmed the binding of TXF with IRE1α, and predicted its binding site, suggesting that the structure of TXF itself participates in the inhibition of IRE1α. Interestingly, CYS-951 was just near the docked site. In addition, the RNase IC 50 and ROS production in vitro induced by TXF and its derivatives were negative correlated ( r = −0.872). In conclusion, this study discovers a new type of IRE1α inhibitor that targets a predicted new alternative site located in the junction between RNase domain and kinase domain, and oxidizes conserved cysteine residues of IRE1α active sites to inhibit IRE1α. TXF could be used as a small molecule tool to study IRE1α’s role in ER stress.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2022
·Vol. 26
·期 10
·2219-2229
·
IF 2.747
Kang Xianyu,Qiao Xingxing,Zhao Jingchuang,Li Yancai,Lü Jian
In this work, mesoporous carbons (MCs) were synthesized by a template method, and the schwertmannites (Schs) were prepared by a calcination method. They were mixed uniformly by ultrasound and obtained the Schs/MCs nanocomposites. The Schs/MCs/GCE can be used to detect paracetamol (PA) and dopamine (DA) simultaneously. Under the best terms, it exhibits wide linear range of 1.0 to 300 µM for PA and 1.0 to 400 µM for DA. The determination limits are 0.33 µM for PA and 0.24 µM for DA ( S / N = 3), respectively. Besides, the sensor is expected to be used for detect PA and DA in pharmaceutical samples.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 24
·11274-11288
·
IF 4.682
Yang Bin,Yang Yingdong,Xu Xiang,Ke Yuchao,Pan Yang,Su Lifen,Wang Yingying,Wang Shuqing,Qian Jiasheng,Xia Ru,Fu Enfa
Lithium-ion batteries (LIBs) have attracted more and more attention in recent years because of their renewable, clean energy and high-cost performance. Polyvinylidene fluoride (PVDF) and polymethyl methacrylate (PMMA) were expected to be used in the preparation of LIB separator due to their excellent comprehensive properties. In this work, a series of PVDF/PMMA LIB separators were prepared by thermally-induced phase separation (TIPS), which is a simple method of fabricating microporous films. In order to improve the comprehensive performance, SiO 2 was adopted to modify the composite films with various filling proportions by solution method. Results of DSC and XRD tests showed that SiO 2 nanoparticles could significantly reduce the crystallinity of the films, but hardly changed the morphology of PVDF. With an increase in SiO 2 content, both porosity and electrolyte uptake rate for the composite films increased, but an excessive loading of SiO 2 tended to agglomerate inside the films. The porosity and electrolyte uptake rate for composite film containing 3% SiO 2 were found to be the highest. As SiO 2 loading increased, both first charge–discharge capacity and efficiency of the composite films were enhanced with the discharge cycle stability enhanced simultaneously. When 3% SiO 2 was incorporated, the PVDF/PMMA/SiO 2 composite film displayed the best comprehensive performance of the battery among all film samples examined. This study presents a facile way of manufacturing LIB separators with relatively ideal overall battery performance.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POROUS MATERIALS
·
2022
·Vol. 29
·期 5
·1489-1505
·
IF 2.523
Chang Ziling,Li Huafei,Yang Yuxiang,Yuan Hongming,Huang Yan,Yao Pingping,Ni Chaoying
Herein, we developed the dual-function template method to fabricate hollow magnetic nano-spheres (denoted as HMFe–Si–C n , n = 16, 18) with a mesoporous shell and hollow interior structure using alkyl chain trimethoxysilane templating. The shorter chain template directed formation of HMFe–Si–C 16 with size of 119 nm, having disordered inkbottle type mesopores and saturation magnetization of 50.01 emu/g higher than that of HMFe–Si–C 18 with cylindrical type mesopores. In addition, the HMFe–C n loaded with MMC diaplays a pH and magnetic dual responsive drug release behavior. By contrast, Mitomycin C (MMC) loading efficiency of HMFe–Si–C 16 was higher owing to the fact that the pore size, surface area, and pore volume of HMFe–Si–C 16 were larger than those of HMFe–Si–C 18 . Besides, MMC loaded HMFe–Si–C n hollow spheres showed a clear pH-dependent drug release behavior, having a higher release rate in acidic environments of pH 5.7. For the pH 5.7 and 7.4 release, the release kinetic for HMFe–Si–C 16 –MMC composites follows pseudo-first-order attributable to its special pore structure. With Fe(0) as a core, HMFe–Si–C n is distinguished for higher magnetic properties, and it is more conducive to magnetic targeted treatment of cancer cells and can release drugs through external magnetic field. In addition, HMFe–Si–C n has lower cytotoxicity and better biocompatibility. For this reason the inner cavity of HMFe–Si–C 16 could be labeled with radioisotope 99 Tc m to study the magnetic targeting distribution of HMFe–Si–C 16 in vivo, and its cytotoxicity against in vitro HeLa cells was also studied. These results indicate the potential of HMFe–Si–C 16 in the magnetic targeted drug delivery system.
✓ 已验证
产品关联
DOI
高影响因子
Bioresources and Bioprocessing
·
2022
·Vol. 9
·期 1
·1-17
·
IF 4.983
Fan Jie,Yu Qiongfen,Li Ming,Chen Jie,Wang Yunfeng,Zhang Ying,Li Guoliang,Ma Xun,Zhong Hao,Yu Yamei
Lignin is a renewable bioresource that can be used for a variety of value-added applications. However, the effective separation of lignin from lignocellulosic biomass remains an ongoing challenge. In this study, lignin was extracted from waste palm fiber and successfully converted into a dehumidifying material. The following four process parameters of lignin extraction from palm fiber were optimized systematically and comprehensively using the response surface methodology: reaction time, extraction temperature, ethanol concentration and solid/liquid ratio. The results revealed that under the optimum processing conditions (111 min of extraction at 174 °C using 73% ethanol at 1/16 g/mL solid/liquid ratio), the extraction yield of lignin was 56.2%. The recovery of ethanol solvent was as high as 91.8%. Further, the lignin could be directly used without purification to produce lignin-based activated carbon fibers (LACFs) with specific surface area and total pore volume of 1375 m2/g and 0.881 cm3/g, respectively. Compared with the commercial pitch-based activated carbon fiber, the LACF has a higher specific area and superior pore structure parameters. This work provides a feasible route for extracting lignin from natural palm fiber and demonstrates its use in the preparation of activated carbon fiber with a remarkable performance as a solid dehumidification agent.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF POROUS MATERIALS
·
2022
·Vol. 29
·期 5
·1463-1477
·
IF 2.523
Tao Jianghui,He Juan,Wang Yanni,Wang Yabin
As for supported noble metal catalysts, the aggregation, leaching, and migration of the noble metals are fatal to their catalytic performances. Up to now, it is still challengeable to not only highly load and finely disperse noble metal nanopartcicles (NPs) onto the support platforms, but also maintain the physicochemical state of the already anchored NPs. Herein, for the first time, we have found that hybrid dendritic mesoporous silica&titania nanospheres (DMSTNs) and the coupled mercapto groups (–SH) on their surface could remarkably load and disperse ultrafine silver (Ag) NPs simultaneously. The as-prepared DMSTNs-SH-Ag composite catalyst exhibits more superior abilities for photocatalytic water splitting, p -nitrophenol reduction without light irritation, and antibacteria, in comparison to pure dendritic mesoporous silica nanospheres (DMSNs)-based catalysts like DMSNs-SH-Ag or amino groups (–NH 2 ) functionalized ones (e.g., DMSTNs-NH 2 -Ag and DMSNs-NH 2 -Ag). The improvement can be attributed to the unique physicochemical and structural advantages of DMSTNs-SH supports that bring about desirable loading and dispersion of Ag NPs, the decreased recombination rate of the photo-generated electron–hole pair, the longer route of electron migration, etc. DMSTNs-SH-Ag also exhibit stable recycling and leaching-resistant abilities. The access to DMSTNs-SH-Ag is simple, facile, and economical, which could be versatile for anchoring other noble metals as well theoretically.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2022
·Vol. 26
·期 8
·1605-1612
·
IF 2.747
Hu Jie,Li Jingying,Wei Zhengnan,Zhang Shuying
“Rocking-chair” zinc-ion batteries (ZIBs) are potential commercial energy storage devices because of their high energy density and safety. However, using appropriate cathode materials with weak polarization effect and tolerating the rapid insertion/extraction of zinc ions are still the huge challenges. Here, a WSe 2 nano-flower cathode material with hierarchical structure is successfully prepared by a facile solvent thermal strategy. The electrochemical data confirm that the WSe 2 cathode has high specific discharge capacity (545 mA h g −1 at 0.1 A g −1 ), excellent rate performance, and stable cyclic performance (81% after 100 cycles), which are superior to most reported electrode materials. The layered structure is beneficial to increase the specific surface area and conductivity of the electrode material and improve the battery discharge performance. This study opens new opportunities to promote the commercialization of rechargeable aqueous ZIBs.
✓ 已验证
产品关联
DOI
高影响因子
Biomass Conversion and Biorefinery
·
2022
·
IF 4.05
Liao Jun,He Xiaoshan,Zhang Yong,Zhang Lin,He Zhibing
The purpose of this study was to develop a carbon material with excellent adsorption performance of uranium, which could effectively reduce the risk of damage to the water environment caused by pig manure (PM) and uranium-containing wastewater. Three kinds of biochars (PMBC-300, PMBC-500, and PMBC-700) were successfully constructed with pig manure as the precursor at different carbonization temperature (300, 500, and 700 °C) for removing uranium from the solution. Meanwhile, various adsorption isotherm and kinetics models were applied to deeply discuss the adsorption performances and mechanism of pig manure-derived biochar for uranium. The results showed that the surface charge and active sites of PMBC were the important parameters to affect the removal of uranium. The adsorption capacity of PMBC-500 reached 376.5 mg/g (m/V = 0.1 g/L, pH = 4, and T = 298 K) due to the abundant active sites (phosphate, carbonate, and oxygen-containing groups), which was much higher than that of other reported carbon materials. Therefore, it could be considered that the conversion of PM into PMBC was a feasible method, which would effectively remove uranium from the solution and reduce the pollution of PM to the environment. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
Communications Chemistry
·
2022
·Vol. 5
·期 1
·1-10
·
IF 7.211
Wang Fengkai,Han Shurui,Zhang Yanli,Gao Lei,Li Xu,Zhao Lizhi,Ye Hui,Li Hong,Xin Qingping,Zhang Yuzhong
Membrane technology is an effective strategy for gas dehumidification and fuel cell humidification. In this study, cerium fluoride oxide (F-Ce) two-dimensional (2D) mesoporous nanosheets and their composite with 1-ethyl-3-methylimidazolium dicyanamide ([Emim][DCA]) ionic liquids (ILs) (IL@F-Ce) are introduced as fillers into polyether block amide (PEBAX® 1074) to fabricate mixed matrix membranes (MMMs). The slit-shaped mesoporous structure of the nanosheets facilitates the construction of water vapor rapid transport channels in MMMs. The permeability and selectivity of water vapor for MMMs loaded with F-Ce nanosheets are greatly improved, and the performance of MMMs loaded with IL@F-Ce nanosheets are much better than the former. Particularly, the MMM with IL@F-Ce content of 4 wt.% achieves the highest H 2 O permeability of 4.53 × 10 5 Barrer, which is more than twice that of the pure PEBAX membrane, and the selectivity is increased by 83%. Thus, the MMMs based on 2D mesoporous nanosheets have considerable potential application in industrial-scale dehydration and humidification processes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Light-Science & Applications
·
2022
·Vol. 11
·期 1
·1-10
·
IF 20.257
Xie Yao,Song Yapai,Sun Guotao,Hu Pengfei,Bednarkiewicz Artur,Sun Lining
The continuously growing importance of information storage, transmission, and authentication impose many new demands and challenges for modern nano-photonic materials and information storage technologies, both in security and storage capacity. Recently, luminescent lanthanide-doped nanomaterials have drawn much attention in this field because of their photostability, multimodal/multicolor/narrowband emissions, and long luminescence lifetime. Here, we report a multimodal nanocomposite composed of lanthanide-doped upconverting nanoparticle and EuSe semiconductor, which was constructed by utilizing a cation exchange strategy. The nanocomposite can emit blue and white light under 365 and 394 nm excitation, respectively. Meanwhile, the nanocomposites show different colors under 980 nm laser excitation when the content of Tb 3+ ions is changed in the upconversion nanoparticles. Moreover, the time-gating technology is used to filter the upconversion emission of a long lifetime from Tb 3+ or Eu 3+ , and the possibilities for modulating the emission color of the nanocomposites are further expanded. Based on the advantage of multiple tunable luminescence, the nanocomposites are designed as optical modules to load optical information. This work enables multi-dimensional storage of information and provides new insights into the design and fabrication of next-generation storage materials.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）