CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Xiuqin Fang,Chang Wang,Hong-Hui Shu,Sheng-Li Han,Cheng-Mei Liu
Bisphenol A (BPA), a prominent endocrine-disrupting compound, has garnered considerable attention due to its urgent need for rapid removal from water. Herein, we first used a novel reactive phosphine oxide containing tertiary amines as crosslinker to prepare water-insoluble crosslinked β-cyclodextrin (β-CD) adsorbent via radical-mediated thiol–ene polymerization. Owing to the synergistic hydrogen-bond (H-bond) interactions of functional groups (tertiary amine and P O groups) toward BPA, the resulted adsorbents showed fast adsorption kinetics to BPA with an adsorption equilibrium time of 5 min. After six adsorption–desorption cycles, the removal efficiency of BPA was 92.5 %, indicating its excellent reusability. Due to the presence of the C S bonds, the β-CD -derived bio-adsorbents offered binding sites for Cu 2+ ions, resulting in a maximum adsorption capacity of 113.89 mg g −1 .
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Materials Today Chemistry
·
2024
·
IF 6.7
Jian Gou,Yousong Hu,Luxin Xing,Jun Xu,Fengzhi Yue,Lina Zhang,Lei Jia
Traditional luminescent materials for anti-counterfeiting usually adopt encryption of low-level systems with limited security, which seriously hinders their application in preventing counterfeiting and information leakage. Therefore, it is urgent to develop materials for higher-level anti-counterfeiting. In this work, a stimulus-responsive intelligent luminescent material (AC@CDs-Eu-MOFs) was prepared by co-loading green-fluorescence CDs and red-fluorescence Eu-MOFs on Amino clay (AC). 5D security barcodes, which were easy to observe while difficult to clone, were ulteriorly designed based on the nanocomposite owing to the tunable fluorescence by optical stimulation and chemical stimulus. Owing to the large capacity, low cost, and easy authentication, the 5D security barcodes possess enormous potential in optical data storage and multi-dimensional information encryption. In addition, the chemical stimulus-response enables the nanocomposite achievable in detection of Cu 2+ and Bacillus anthracis. Particularly, quantitative determination of copper in environmental water samples could be realized with a detection limit as low as 10.67 nM. Therefore, the material shows potential for detection of environmental pollutants besides advanced anti-counterfeiting.
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ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Yiqiang Yu,Xuejing Li,Qiao Ying,Zhanwei Zhang,Weicai Liu,Jiansheng Su
The primary pathology of periodontitis involves the gradual deterioration of periodontal tissues resulting from the inflammatory reaction triggered by bacterial infection. In this study, a novel drug for periodontal pocket injection, known as the Shed-Cu-HA hydrogel, was developed by incorporating copper ions (Cu2+) and Shed-derived exosomes (Shed-exo) inside the hyaluronic acid (HA) hydrogel. Suitable concentrations of Cu2+ and Shed-exo released from Shed-Cu-HA enhanced cell viability and cell proliferation of human periodontal ligament stem cells. Additionally, the Shed-Cu-HA demonstrated remarkable antibacterial effects against the key periodontal pathogen (Aa) owing to the synergistic effect of Cu2+ and HA. Furthermore, the material effectively suppressed macrophage inflammatory response via the IL-6/JAK2/STAT3 pathway. Moreover, the Shed-Cu-HA, combining the inflammation-regulating properties of HA with the synergistic osteogenic activity of Shed-exo and Cu2+, effectively upregulated the expression of genes and proteins associated with osteogenic differentiation. The experimental findings from a mouse periodontitis model demonstrated that the administration of Shed-Cu-HA effectively reduced the extent of inflammatory cell infiltration and bacterial infections in gingival tissues and facilitated the regeneration of periodontal bone tissues and collagen after 2 and 4 weeks of injection. Consequently, it holds significant prospects for future applications in periodontitis treatment.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Xiaolun Peng,Jiaxin Zheng,Ting Bao,Wei Wen,Xiuhua Zhang,Shengfu Wang
A novel dual-amplified electrochemical biosensor based on Exonuclease III (Exo III) and Cu(II)-dependent DNAzymes (Cu 2+ -DNAzymes) was developed for ultrasensitive electrochemical evaluation of pyrophosphatase (PPase) activity with the help of one-step synthesis of BSA-directed gold nanoclusters-manganese dioxide (AuNCs-MnO 2 ) nanoflakes with peroxidase-like characteristics as a catalytic platform. For biosensor preparation, under the catalytic hydrolysis of the PPase, copper ion (Cu 2+ ) was released from the Cu 2+ -coordinated pyrophosphate ions (Cu 2+ –PPi) complex which was formed by the coordination reaction of copper ion (Cu 2+ ) and pyrophosphate ions (PPi). The released Cu 2+ , acting as an indispensable cofactor, could activate Cu 2+ -DNAzymes to turn on the amplification process and then generated the single-stranded product (S1) that hybridized to the hairpin-type capture probe (HP1). Subsequently, the addition of Exonuclease III (Exo III) enabled the reuse of S1 and produced the final cleavage fragment, which closely linked the functionalized AuNCs-MnO 2 nanoflakes to the electrode surface. The superior peroxidase-like characteristics of nanoflakes provided stable catalytic signal output and realized electrochemical monitoring of PPase activity with a detection limit of 0.0058 mU/mL. Importantly, the biosensor also had a good performance in inhibitors screening of target PPase. The use of AuNCs-MnO 2 nanoflakes instead of natural enzymes combined with DNAzymes amplification strategy offered more possibilities for the detection of various biomolecules.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Xu Chen,Mengjun Qiu,LiPing Liu,Qin Ji,Zushun Xu,Zhifan Xiong,Shengli Yang
A novel nanoplatform that supports multimodal imaging has been designed for deep tumor therapy. In this study, Bi 2 Se 3 @Cu 2−x Se heterojunction nanocomposites with tunable spectral absorption, effective electron–hole separation and high photothermal conversion efficiency were prepared for the combination therapy of phototherapy (PT), chemodynamic therapy (CDT) and radiotherapy (RT). By adjusting the doping ratio, the heterojunction nanoparticles show obvious tunable ability of local surface plasmon resonance and the ability to promote electron-hole separation with significantly enhanced reactive oxygen species production capacity. The band structure and charge density difference calculated by density functional theory further reveal that the change of band gap and the decrease of free carriers can regulate the spectral absorption of nanomaterials and promote electron-hole separation. In addition, the photothermal conversion properties of low carrier density semiconductors are related to their inherent deep level defects. The formation of heterojunctions making the Se atoms deviate from the Bi 2 Se 3 lattice, resulting in more deep level defects and stronger photothermal conversion properties. Meanwhile, this nanoplatform presented features similar to catalase activities and glutathione (GSH) consumption characteristics, which was capable of effectively alleviate the tumor-specific hypoxia environment to enhance the efficacy of O 2 -dependent photodynamic therapy (PDT) and radiotherapy (RT) and depletion GSH to prevent the reduction of therapeutic efficacy due to the clearance of reactive oxygen species. In addition to therapeutic enhancement, heterojunction nanomaterials have excellent nuclear magnetic resonance imaging (MRI), infrared thermal imaging (IR) and computed tomography (CT) properties due to their significant paramagnetism and excellent photothermal conversion and X-ray attenuation capacities. In conclusion, our findings provide a new strategy for designing multi-function and efficient nanoplatform to treat tumor.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
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IF 9.038
Abdur Raheem Aleem,Jin Liu,Jing Wang,Jing Wang,Yue Zhao,Yao Wang,Yanxin Wang,Wei Wang,Faisal UL Rehman,Matt J. Kipper,Jianguo Tang
Fluorescent lanthanide complexes have favorable features for fluorescence-based sensors compared to organic fluorophores and quantum dots. They exhibit very long fluorescence lifetimes, sharp emission bands, and stability with respect to photo-bleaching, without blinking. However, these complexes are usually hydrophobic, and many are excited by UV light, making them hazardous and incompatible with aqueous environments and biological samples. In this work, the strong fluorescent Eu 3+ -induced aggregates of polysaccharides (EIAP) was used to improve their aqueous solubility, and to tune the appropriate excitation wavelength in the visible range for avoiding toxicity of UV light in biological applications. The complexes exhibit bright fluorescence with an excitation maximum in the visible range, near 405 nm. EIAP 3 also exhibit rapid quenching response in the presence of transition metal ions. This enables the detection of Cu 2+ and Fe 3+ below 1 ppm. The reverse of quenching response of copper by the addition of a chelating agent makes it possible to recover the fluorescence property. Successfully, the EIAP exhibit cytocompatibility with mammalian cells. Thus, these new polysaccharide-based complexes have the potential for rapid, sensitive and selective metal ion sensors for the environmental systems.
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CRYSTENGCOMM
·
2023
·Vol. 25
·期 8
·1232-1239
·
IF 3.1
Gui-Mei Huang,Shuang Li,Meng-Xia Ma,Shi-Ming Li,Wen-Qiang Li,Qing-Ling Ni,Liu-Cheng Gui,Xiu-Jian Wang
Four MOFs with mixed ligands, [Zn3(3-BABA)2(bpa)2(H2O)2]n (1), [Cd3(3-BABA)2(bpa)2]n (2), [Cd3(3-BABA)2(bpe)2]n (3), and {[Cd3(3-BABA)2(bib)(DMA)2]·H2O}n (4) (where 3-H3BABA = 4′,4′′′-(((2-carboxyphenyl)azanediyl)bis(methylene))bis(([1,1′-biphenyl]-2-carboxylic acid)), bpa = 4,4′-azopyridine, bpe = 1,2-bis(pyridin-4-yl)ethane, and bib = 1,4-bis(imidazole)butane), have been synthesized. They are characterized by single crystal X-ray diffraction, X-ray powder diffraction (XRPD), thermogravimetric analysis (TGA) and Fourier transform infrared (FT-IR) spectroscopy. In 1, two 3-BABA and two bpa bridge three Zn2+ ions to form a bicyclic [Zn3(3-BABA)2(bpa)2] unit which is further bridged by carboxylate groups with its adjacent units, resulting in a one-dimensional chain. In 2, 3 and 4, the [Cd3(CO2)6] units are bridged by six 3-BABA ligands into a three-dimensional structure. However, the adjacent [Cd3(CO2)6] units in 2 and 3 are doubly-bridged simultaneously by corresponding pyridyl ligands, while the adjacent [Cd3(CO2)6] units in 4 are singly-bridged simultaneously by corresponding pyridyl ligands. The luminescence sensing investigation indicates that compound 1 exhibits extremely sensitive and selective detection of Cu2+ with a detection limit of 0.363 μM, and compounds 2–4 show extremely sensitive and selective detection of Fe3+ with detection limits of 0.539 μM, 0.265 μM, and 0.748 μM, respectively. Competitive experiments in the presence of interfering cations with 1–4 revealed no major change in the quenching efficiency.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yiji Chen,Liang He,Shirong Ai,Hang Yao,Aihua Xiong,Li Li,Jiang Li,Zhongshou Liu,Yansha Gao,Ruimei Wu,Limin Lu
Simultaneous and accurate analysis of multiple heavy metals (HMs) in environment by electrochemical method still faces huge challenges, such as complex experimental process, low detection efficiency and the interference arising from electrochemical interactions between different HMs. To address these issues, we propose a sensing platform combining S-TiO 2 @Ti 3 C 2 MXene with machine learning strategies for simultaneous electrochemical detection of Cu 2+ and Hg 2+ in water samples. Specifically, surface morphology and crystal structure of S-TiO 2 @Ti 3 C 2 were characterized via SEM, XRD, and XPS. Electrochemical behaviors were systematically investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Orthogonal test-based multi-objective optimization method integrated with comprehensive balance approach were employed to determine the optimal sensing parameters, which were identified pH of 4.5, deposition time of 210 s, and deposition potential of −1.5 V. The fabricated sensor exhibited high sensitivities of 44.122 and 143.795 μA·L·mg −1 , low limits of detection of 0.392 and 0.093 μg·L −1 , and broad linear ranges of 0.001–1000 μg·L −1 for Cu 2+ and Hg 2+ , respectively. Furthermore, machine learning strategy was introduced to resolve the poor accuracy issue associated with traditional calibration curve analysis for the simultaneous detection of Cu 2+ and Hg 2+ across the entire linear range. The results indicated that minimum Redundancy Maximum Relevance (mRMR) algorithm effectively extracted valuable and critical information of Cu 2+ and Hg 2+ from the full voltammetric curves, and the constructed support vector machine (SVM) model remarkably improved detection accuracy. The reliability of the proposed SVM model was validated through simultaneous detection of HMs in actual environmental water samples, yielding favorable recovery rates.
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TALANTA
·
2016
·
IF 4.035
Haiyang Liu,Bibo Zhang,Chunyan Tan,Feng Liu,Jiakun Cao,Ying Tan,Yuyang Jiang
A simple Schiff base (BMSA) prepared from salicylaldehyde and 2-(1H-benzo[ d ]imidazol-2-yl)aniline was evaluated as an efficient fluorescent chemosensor for the selective recognition of Al 3+ and Cu 2+ over other common metal ions . This sensor could detect Al3 + in CH 3 OH/PBS with distinct emission red-shift (the detection limit 0.31 μM)and Cu 2+ in CH 3 OH/Tris-HCL (the detection limit 0.54 μM) with obvious fluorescence quenching . The obtained BMSA-Al 3+ and BMSA-Cu 2+ complexes could act as cascade sensors for detecting F − and S 2− , respectively. The recognizing behavior of BMSA toward Al 3+ and Cu 2+ has been investigated in detail through Job's Plot, FT-IR NMR , and HRMS analysis. Moreover, this chemosensor was verified to be of low cytotoxicity and good imaging characteristics for the detection of Al 3 + and Cu 2+ , and further for the recognition of F − and S 2− in living cells, suggesting that BMSA was proved to be a useful tool for tracking Al3 + /Cu 2+ and F − /S 2− ions in vivo .
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INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Yi-Heng Wang,Yang Liu,Jin Tong,Shu-Yan Yu
The cyclometalated Ir(III) complex, Ir(ppy) 2 (phen-dipzH 2 ) ( Ir-1 ), was synthesized using the ligand 3,8-di(1H-pyrazol-4-yl)-1,10-phenanthroline (phen-dipzH 2 ) and the auxiliary ligand 2-phenylpyridine (ppy). Crystal structure analysis reveals that each {Ir(ppy) 2 } + unit is coordinated by a neutral phen-dipzH 2 ligand in Ir-1 . The packing arrangement of Ir-1 displays aromatic stacking interactions and [C–H…N] hydrogen bonding interactions between the [Ir(ppy) 2 (phen-dipzH 2 )] + cations. In solution, Ir-1 exhibits emission switching induced by acid/base changes, with the emission wavelength shifting from 562 nm (yellow color) in the neutral state to 618 nm (pink color) under acidic conditions and to 528 nm (gray color) under basic conditions. These shifts are attributed to the protonation and deprotonation of the pyrazole units, which is confirmed by 1 H NMR spectra. Additionally, Ir-1 demonstrates high selectivity and sensitivity toward Cu 2+ ions, with a detection limit as low as 9.47 μM compared to other metal ions. The acid/base-responsive phosphorescence of Ir-1 has also been successfully utilized in the development of paper strip-based devices for urea detection.
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ANALYTICA CHIMICA ACTA
·
2023
·
IF 6.2
Weiqing Xu,Farid Ahmed,Hai Xiong
A rhodamine hydrazide conjugating uridine moiety (RBH-U) is firstly synthesized by screening different synthetic routes, and then developed as a fluorescence probe for selective detection of Fe 3+ ions in an aqueous solution, accompanied by visual color change with naked eyes. Upon the addition of Fe 3+ in a 1:1 stoichiometry , a 9-fold enhancement in the fluorescence intensity of the RBH-U was observed with an emission wavelength of 580 nm. In the presence of other metal ions , the “turn-on” fluorescent probe with pH-independent (value 5.0 to 8.0) is remarkably specific for Fe 3+ with a detection limit as low as 0.34 μM. Further, the enhanced fluorescence intensity of RBH-U- Fe 3+ can be quenched as a switch-off sensor to assist in the recognition of Cu 2+ ions. Additionally, the colocalization assay demonstrated that RBH-U containing uridine residue can be used as a novel mitochondria-targeted fluorescent probe with rapid reaction time. Cytotoxicity and cell imaging of RBH-U probe in live NIH-3T3 cells suggest that it can be a potential candidate for clinical diagnosis and Fe 3+ tracking toll for the biological system due to its biocompatibility and nontoxicity in NIH-3T3 cells even up to 100 μM.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Xiaoshi Lang,Ruiyin Ren,Xinxi Wang,Lan Li,Kedi Cai
Lithium-sulfur batteries are considered as promising energy storage systems owing to rather high theoretical specific capacity (1675 mAh.g −1 ) and low cost. Nevertheless, the practical prospect is always limited owing to some short-comings, such as sulfur insulation, volume alternation and shuttle effect. To solve these problems, Cu 2+ regulated Fe 2 O 3 nanospheres (Fe 1−x Cu x O 1.5-δ ) as high-performance matrixes for sulfur composite cathodes of lithium-sulfur batteries are constructed via a facile hydrothermal method . It indicates that Cu 2+ regulation can increase the lattice size and exhibit uniform nanospheres micromorphology with less serious agglomeration. Moreover, as sulfur loading material can realize the joint effect on the physical and chemical confinement and some dissociate excess Cu 2+ with sulfur also can directly compose some Cu-S structures, further stabilizing the structure of sulfur composite cathode. In addition, Fe 0.6 Cu 0.4 O 1.5-δ /S composite cathode with sulfur loading mass ratio to 1:3 has fast electrochemical reaction kinetics with the low charge transfer resistance (25.54 Ω) and the high lithium-ion transfer efficiency (D Li+ =2.59 ×10 −12 cm 2 ·s −1 ) and the initial specific discharge capacities and ideal capacity retention accompanied by a charge and discharge voltage platform with small fluctuation.
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