JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·Vol. 27
·期 3
·753-761
·
IF 2.5
Chu Youqun,Zhang Huixuan,Zhou Huihui,Xu Tengfei,Yan Hui,Huang Zhangkao,Zhao Fengming
The nano-Ag–TiO 2 hollow microsphere precursors were prepared by the one-pot solvothermal method using L-tyrosine as the template agent and reducing agent. Subsequently, the nano-Ag–TiN hollow microsphere composites were formed by reducing nitride in an ammonia-filled atmosphere. The esterification of ethanol solvent and L-tyrosine microdroplet template generates traces of water in situ for the hydrolysis of alkane titanium. As the L-tyrosine microdroplet templates are sacrificed and incorporated into the titanium dioxide matrix, a hybridized hollow structure is formed. With the help of L-tyrosine, the surface of Ag–TiO 2 hollow microsphere precursors appeared folded rough surface, and the nanosilver was mostly distributed in the TiO 2 spherical shell. The constructed Ag–TiO 2 hollow microsphere demonstrated a good linear relationship between the current response value and the concentration in the range of 0.2–220 μM of H 2 O 2 , with the lowest detection limit of 0.04 μM. In the same concentration range, whereas the lowest detection limit of Ag–TiN hollow microsphere was 0.02 μM. The detection results of H 2 O 2 revealed that the Ag–TiN/HMS electrode has outstanding interference resistance, stability, and repeatability.
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Scientific Reports
·
2022
·Vol. 12
·期 1
·1-13
·
IF 4.996
Zhou Bin,Sha Shanshan,Tao Juan,Li Jun,Shen Chen,Zhu Jinjin,Tan Lulu,Dong Liyun,Huang Changzheng
Cutaneous melanoma (CM, hereafter referred to as melanoma) is a highly malignant tumor that typically undergoes early metastasis. Pyroptosis, as a special programmed cell death process that releases inflammatory factors and has been widely studied in tumors, but its role in melanoma has not been fully elucidated. In this study, we examined the relationship between pyroptosis and the prognosis of melanoma through bioinformatic analysis of RNA-sequencing data. Our results demonstrated that pyroptosis is a protective factor associated with melanoma prognosis. A higher pyroptosis score was associated with a more favorable overall survival. We used weighted gene co-expression networks analysis (WGCNA) to establish an effective prognosis model based on 12 pyroptosis-related genes. We then validated it in two independent cohorts. Furthermore, a nomogram combining clinicopathological characteristics and a pyroptosis-related gene signature (PGS) score was designed to effectively evaluate the prognosis of melanoma. Additionally, we analyzed the potential roles of pyroptosis in the tumor immune microenvironment and drug response. Interestingly, we found that the elevated infiltration of multiple immune cells, such as CD4 + T cells, CD8 + T cells, dendritic cells, and M1 macrophages, may be associated with the occurrence of pyroptosis. Pyroptosis was also related to a better response of melanoma to interferon-α, paclitaxel, cisplatin and imatinib. Through Spearman correlation analysis of the 12 pyroptosis-related genes and 135 chemotherapeutic agents in the Genomics of Drug Sensitivity in Cancer database, we identified solute carrier family 31 member 2 ( SLC31A2 ) and collagen type 4 alpha 5 chain ( COL4A5 ) as being associated with resistance to most of these drugs. In conclusion, this PGS is an effective and novelty prognostic indicator in melanoma, and also has an association with the melanoma immune microenvironment and melanoma treatment decision-making.
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Nano Research
·
2022
·Vol. 16
·期 6
·8417-8424
·
IF 10.269
Li Wanxia,Jie Yulin,Chen Yunhua,Yang Ming,Chen Yawei,Li Xinpeng,Guo Youzhang,Meng Xianhui,Cao Ruiguo,Jiao Shuhong
Enhancing the cut-off voltage of high-nickel layered oxide cathodes is an efficient way to obtain higher energy density of lithium-metal batteries (LMBs). However, the phase transition of the cathode materials and the uncontrolled decomposition of the electrolytes at high voltage can lead to irreversible dissolution of transition metal ions, which might cause the crossover effects on the lithium metal anodes. Nonetheless, the mechanism and electrolyte dependence of the crossover effects for Li metal anodes are still unclear. Herein, we investigate the crossover effects between LiNi 0.8 Mn 0.1 Co 0.1 O 2 and Li-metal anode in two electrolyte systems. For ether-based electrolyte, its poor oxidation stability results in massive dissolution of transition metal ions, leading to dendrite growth on anode and rapid cells failure. Conversely, ester-based electrolyte exhibits good electrochemical performances at 4.5 V with little crossover effect. This study provides an idea for electrolyte systems selection for high-voltage LMBs, and verifies that the crossover effect should not be neglected in LMBs.
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WATER AIR AND SOIL POLLUTION
·
2023
·Vol. 234
·期 2
·1-12
·
IF 2.9
Wang Ke,Huang Changjiang,Tang Jun,Liu Shuai,Miao Yuqing,Liu Yuntong,Wu Chuansheng
Bisphenol A (BPA) reportedly exerts concentration-dependent effects on plant growth, based on hydroponic exposure experiments. However, this pattern might differ in soil substrate, and the effects of different BPA concentrations in soil on crop germination as well as symbiotic relationship with rhizobia remain largely unclear. In this study, we evaluated the effects of different BPA concentrations (0, 10, 20, 40, 80, 160, and 320 mg/kg air-dry soil) on soybean growth index, germination, and root nodule by soil culture experiments. Results showed that low-dose BPA (10 mg/kg) treatment resulted in a 38.0 and 59.4% increase in total biomass and yield, respectively, while germination time was shortened by 10.1%. Conversely, high-dose BPA treatment significantly inhibited total biomass, yield, and germination time by an average of 39.9, 35.4, and 31.3% in 160 and 320 mg/kg, respectively. Root nodule biomass decreased in all BPA treatments, especially significantly decreased evenly by 66.6% in high concentrations of 160 and 320 mg/kg. Furthermore, germination time significantly explained variations of total biomass and yield by 19.2 and 18.3%, whereas nodule biomass significantly explained by 40.4 and 26.2%, respectively. The structural equation modeling revealed that BPA inhibited soybean total biomass and yield by prolonging germination time and inhibiting soybean nodule formation, while nodule biomass exhibited a larger path coefficient (0.553 and 0.475) than germination time (− 0.252 and − 0.280), suggesting a more important role of soybean nodule. Collectively, these findings provide invaluable insights into the mechanisms underlying the effects of BPA on crop growth.
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Nature Nanotechnology
·
2023
·Vol. 18
·期 3
·299-306
·
IF 38.3
Wei Pengfei,Gao Dunfeng,Liu Tianfu,Li Hefei,Sang Jiaqi,Wang Chao,Cai Rui,Wang Guoxiong,Bao Xinhe
Tuning catalyst microenvironments by electrolytes and organic modifications is effective in improving CO 2 electrolysis performance. An alternative way is to use mixed CO/CO 2 feeds from incomplete industrial combustion of fossil fuels, but its effect on catalyst microenvironments has been poorly understood. Here we investigate CO/CO 2 co-electrolysis over CuO nanosheets in an alkaline membrane electrode assembly electrolyser. With increasing CO pressure in the feed, the major product gradually switches from ethylene to acetate, attributed to the increased CO coverage and local pH. Under optimized conditions, the Faradaic efficiency and partial current density of multicarbon products reach 90.0% and 3.1 A cm −2 , corresponding to a carbon selectivity of 100.0% and yield of 75.0%, outperforming thermocatalytic CO hydrogenation. The scale-up demonstration using an electrolyser stack achieves the highest ethylene formation rate of 457.5 ml min –1 at 150 A and acetate formation rate of 2.97 g min –1 at 250 A.
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JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 2
·1-12
·
IF 2.8
Shi Gege,Zhan Tianyu,Hu Yufang,Guo Zhiyong,Wang Sui
Conductive hydrogels possess both the physicochemical properties of hydrogels and the electrical properties of intrinsically conductive polymers. It is a versatile material that is widely used in various fields, such as supercapacitors, flexible energy storage, electronic devices, and sensors. Conductive hydrogels with self-adhesion properties can realize self-adhesion on the surface of the detected object to ensure the stability of detection signals. Inspired by the adhesion mechanism of mussels, tannic acid (TA) was modified on carbon nanotubes (TA-CNTs) were prepared on the surface of (MWCNT), which reduced the aggregation of carbon nanotubes, increased the dispersibility of carbon nanotubes in the hydrogel, and achieved good electrical conductivity and self-adhesion of the hydrogel, sodium alginate (SA), TA-CNTs synthesized a stretchable, self-adhesive, conductive double-network hydrogel by one-pot thermal initiation with stability. Hydrogen bonds between PAM and SA, which helps to construct the hydrogel networks with strong mechanical properties. The synthesized hydrogels have high strength, pliable adhesion, and strain sensitivity, showing great development potential in monitoring human motion and personal healthcare applications.
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JOURNAL OF ELECTRONIC MATERIALS
·
2023
·Vol. 52
·期 4
·2794-2806
·
IF 2.1
Li Shengnan,Meng Haoyan,Fan Wentao,Shen Junqing,Xu Shengang,Liu Yingliang,Cao Shaokui
Abstract Woven resistive random access memory (RRAM) is a promising subject in flexible wearable electronic devices. In this work, polyvinylammonium iodate (PVAm·HI) is added to the FAPbI 3 perovskite precursor solution to fabricate a flexible fibrous woven RRAM array by improving the flexibility and stability of FAPbI 3 perovskite. The long carbochain polymer backbone of PVAm serves as nucleation sites and a growth template to improve the perovskite crystallization process, and to in situ crosslink the perovskite grains at the crystal interface. The functional Al@FAPbI 3 :PVAm fibers are then prepared by solution dip-coating to assemble the fibrous crosspoint RRAM device with the structure of Al@FAPbI 3 :PVAm/Al by crossing bare aluminum (Al) fibers with functional fibers. Compared to a pristine device, the PVAm-modified devices exhibit a considerable improvement in the ON/OFF ratio and environmental stability. Specifically, the 2% PVAm-modified FAPbI 3 RRAM devices show an evident bipolar resistive switching (RS) behavior with a high ON/OFF ratio of 10 9 , which can easily achieve multilevel storage by setting the compliance current ( I cc ) to increase the storage density in the crosspoint array. Interestingly, a 100-times bent plastics-encapsulated device still exhibits a good RS behavior. This work provides a facile approach to achieve high-density storage in flexible wearable electronic devices.
Graphical Abstract
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 3
·1-11
·
IF 2.8
Zhu Shuangbao,Li Weizhen,Yuan Weichao,Meng Yiming,Chu Zhongyang,Gan Wenjun
Polymer materials with high thermal conductivity (TC) are from the request of current development in thermal management. The formation of three-dimensional (3D) thermally conductive networks of fillers in polymers matrix can substantially improve the TC of composites. Here, epoxy composites with dual conductive networks were prepared by combining two-dimensional boron nitride nanosheets (2D BNNS), one-dimensional silver nanowires (1D AgNW) and 3D nickel foam (NF). The obtained nanocomposites BNNS/AgNW/NF/EP exhibited a maximum TC of 1.23 W m −1 K −1 , an improvement of 583% in comparison with neat epoxy resin. The storage modulus E′ and glass transition temperature T g of the composites had also been improved significantly. At the same time, the presence of NF could impart the nanocomposites excellent electrical conductivity about ~ 10 5 Sm −1 . This dual-networks strategy can be applied to the preparation of both thermally and electrically conductive nanocomposites for specific multi-functionalized thermal management materials.
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MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 2
·1-8
·
IF 5.7
Li Shenghua,Xiao Lingyu,Xiao Longqian,Tan Hongliang
The potential of coordination polymers (CPs) as a host of integrating multiple guest species to construct a fluorescence resonance energy transfer (FRET) nanoprobe was demonstrated. The ZnCPs built from zinc(II) and adenine was employed as a model of CPs to integrate carbon dot (CD) and phenol red (PR) for producing the FRET nanoprobe (CD/PR@ZnCPs). Benefiting from the confinement effect of ZnCPs, the integrated CD and PR can be brought in close proximity to favor the occurrence of FRET process from CD to PR, which leads to the quenching of CD fluorescence. However, the FRET process was disrupted upon the red-shift of PR absorption from 428 to 562 nm in alkaline medium, and consequently switches on the fluorescence of CD/PR@ZnCPs. Based on this finding, by utilizing urease to hydrolyze urea and mediate medium pH, a turn-on fluorescent method was established for the detection of urease activity. This fluorescent method has a linear response that covers 5 to 150 U/L urease with a detection limit of 0.74 U/L and exhibits an excellent selectivity over other enzymes. The successful determination of urease in saliva samples demonstrates the applicability of the fluorescent nanoprobe in complex biological matrix. Graphical Abstract
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2023
·Vol. 34
·期 2
·1-11
·
IF 2.8
Wu Xiaoping,Chen Long,Hu Haihua,Song Changsheng,Jiang Qi,Wang Peng,Xu Lingbo,Lin Ping,Cui Can
Cu 2 O@SnS 2 heterojunction photocatalysts with one-dimensional hierarchical nanostructure were prepared by the solvothermal method. The Cu 2 O@SnS 2 hierarchical nanostructure is composed of Cu 2 O nanowire core as well as in situ grown ultra-thin SnS 2 nanosheets on Cu 2 O nanowires. The hierarchical Cu 2 O@SnS 2 composite shows higher catalytic activity, and the degradation ratio of MB reaches nearly 100% at 80 min. The first-order reaction kinetic constant of Cu 2 O@SnS 2 is 0.045 min − 1 , which is much higher than that of Cu 2 O (0.003 min − 1 ) and SnS 2 (0.014 min − 1 ). The improvement in photocatalytic performance is mainly due to the formation of typical heterojunction between Cu 2 O and SnS 2 . Photo-induced electrons in the CB of Cu 2 O react with oxygen to form superoxide radicals (·O 2− ) with strong oxidation ability. At the same time, the photo-induced holes in the VB of SnS 2 also have strong oxidation ability, and the two can synergistically induce the degradation of pollutants. In addition, SnS 2 nanosheets not only provide a large number of reaction sites for photocatalytic degradation, but also facilitate the migration of photo-induced carrier to the surface. The unique hierarchical Cu 2 O@SnS 2 microstructure can also promote multiple light scattering within the material to enhance light absorption. Thus, the one-dimensional hierarchical Cu 2 O@SnS 2 is a promising new visible light catalyst, which has potential application prospect in environmental protection and wastewater treatment.
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EXPERIMENTAL AND MOLECULAR MEDICINE
·
2023
·Vol. 55
·期 1
·183-195
·
IF 12.8
Wu Zhuhua,Zhu Li,Nie Xinran,Wei Li,Qi Yong
Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disease characterized by pulmonary vascular remodeling. Excessive growth and migration of pulmonary artery smooth muscle cells (PASMCs) are believed to be major contributors to pulmonary vascular remodeling. Ubiquitin-specific protease 15 (USP15) is a vital deubiquitinase that has been shown to be critically involved in many pathologies. However, the effect of USP15 on PH has not yet been explored. In this study, the upregulation of USP15 was identified in the lungs of PH patients, mice with SU5416/hypoxia (SuHx)-induced PH and rats with monocrotaline (MCT)-induced PH. Moreover, adeno-associated virus-mediated functional loss of USP15 markedly alleviated PH exacerbation in SuHx-induced mice and MCT-induced rats. In addition, the abnormal upregulation and nuclear translocation of YAP1/TAZ was validated after PH modeling. Human pulmonary artery smooth muscle cells (hPASMCs) were exposed to hypoxia to mimic PH in vitro, and USP15 knockdown significantly inhibited cell proliferation, migration, and YAP1/TAZ signaling in hypoxic hPASMCs. Rescue assays further suggested that USP15 promoted hPASMC proliferation and migration in a YAP1/TAZ-dependent manner. Coimmunoprecipitation assays indicated that USP15 could interact with YAP1, while TAZ bound to USP15 after hypoxia treatment. We further determined that USP15 stabilized YAP1 by inhibiting the K48-linked ubiquitination of YAP1. In summary, our findings reveal the regulatory role of USP15 in PH progression and provide novel insights into the pathogenesis of PH.
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FOOD SCIENCE AND BIOTECHNOLOGY
·
2022
·Vol. 32
·期 3
·361-369
·
IF 3.231
Su Anxiang,Ma Gaoxing,Ma Ning,Pei Fei,Yang Wenjian,Hu Qiuhui
Flammulina velutipes polysaccharides (FVP) exhibit many biological activities, but the effects on gut microflora and metabolism were still unclear. Here, we explored the composition of FVP, their influence on human gut microflora composition and metabolites. FVP were used to vitro fermentation through human fecal inoculums. In addition, 16S rRNA sequencing were used to assess the effects of FVP on the gut microbiota. The metabolic profiles were investigated using untargeted metabolomics approaches in the LC-MS platform. The results showed that FVP was mainly consisted of glucose, mannose, xylose, fucose and galactose. FVP is shown to increase the relative abundances of Bifidobacteriaceae , as well as Bacteroidaceae and remarkably decrease the numbers of genera Lachnospiraceae coupled with Enterococcaceae . The differential metabolites were identified and mainly involved the metabolism of glycerophospholipid, linoleic acid and synthesis of unsaturated fatty acids. FVP may exhibit biological activity function by regulating gut microflora composition and metabolites.
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