JOURNAL OF NANOBIOTECHNOLOGY
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2021
·Vol. 19
·期 1
·1-19
·
IF 10.435
Guo Weihong,Chen Zhian,Feng Xiaoli,Shen Guodong,Huang Huilin,Liang Yanrui,Zhao Bingxia,Li Guoxin,Hu Yanfeng
Background Paclitaxel (PTX) has been suggested to be a promising front-line drug for gastric cancer (GC), while P-glycoprotein (P-gp) could lead to drug resistance by pumping PTX out of GC cells. Consequently, it might be a hopeful way to combat drug resistance by inhibiting the out-pumping function of P-gp.Results In this study, we developed a drug delivery system incorporating PTX onto polyethylene glycol (PEG)-modified and oxidized sodium alginate (OSA)-functionalized graphene oxide (GO) nanosheets (NSs), called PTX@GO-PEG-OSA. Owing to pH/thermal-sensitive drug release properties, PTX@GO-PEG-OSA could induced more obvious antitumor effects on GC, compared to free PTX. With near infrared (NIR)-irradiation, PTX@GO-PEG-OSA could generate excessive reactive oxygen species (ROS), attack mitochondrial respiratory chain complex enzyme, reduce adenosine-triphosphate (ATP) supplement for P-gp, and effectively inhibit P-gp’s efflux pump function. Since that, PTX@GO-PEG-OSA achieved better therapeutic effect on PTX-resistant GC without evident toxicity.Conclusion sIn conclusion, PTX@GO-PEG-OSA could serve as a desirable strategy to reverse PTX’s resistance, combined with chemo/photothermal/photodynamic therapy.Graphic Abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2021
·Vol. 56
·期 21
·12212-12223
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IF 4.22
Lu Qi-Lin,Wu Jiayin,Li Yonggui,Li Lu,Huang Biao
The use of lignocellulosic materials for extracting functionalized cellulose nanocrystals (FCNs) in a green and sustainable method under mild conditions is limited owing to the strong hydrogen bonding in cellulose. A facile, green, and high-efficient avenue was developed to produce FCNs with high yield through the mechanochemistry synergetic effect of recyclable p-toluenesulfonic acid (PTSA)-catalyzed deep eutectic solvent (PDES) and microwave- solvothermal (MWS). FCNs with a high charge density of 1.59 e nm −2 , a crystallinity of 81%, a better thermostability and dispersibility were obtained at a high yield of 87.6% by the one-step processing. The PDES could be easily recycled, and thus was beneficial to cost reduction and waste liquor treatment. Generated FCNs could be used to develop functional bionanocomposites due to their enhanced effect. When a loading of 1 wt% FCNs was added into gelatin matrix, the tensile strength and Young’s modulus of the bionanocomposites increased 188 and 131%, respectively, suggesting their remarkable stress transfer potential. Thus, the study demonstrates a green and cost-effective approach for the mass production of FCNs, contributing to strong potential in building high-performance bionanocomposites.
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 32
·43815-43830
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IF 4.223
Liu Yaxin,Ma Yongwen,Wan Jinquan,Wang Yan,Sun Jian,Xue Yangyang
In this work, Co-Ce-Zr/γ-Al 2 O3 3 particle electrodes were prepared for the efficient degradation of ciprofloxacin (CIP). Co-Ce-Zr/γ-Al 2 O 3 particle electrodes were analyzed with a scanning electron microscope (SEM), X-Ray Diffraction (XRD), X-Ray Fluorescence Spectrometer (XRF), X-ray photoelectron spectroscopy (XPS), and energy-dispersive X-ray spectroscopy (EDS). According to the results, significant amounts of Co 3 O 4 , CeO 2 , and ZrO 2 were formed on the Co-Ce-Zr/γ-Al 2 O 3 particle electrodes. It was shown that when the conditions of the reaction system were at pH=6, conductivity of 4 ms/cm, current of 0.2 A, initial pollutant concentration of 100 mg/L, and material dosage of 15 g, CIP could be completely degraded within 40 min, and the energy consumed in the reaction was 41.3 kWh/kg CIP. The rate of total organic carbon (TOC) removal by Co-Ce-Zr/γ-Al 2 O 3 particle electrodes was recorded to be approximately 52.6%. Using a response surface methodology, we explored the optimal operating conditions. At the same time, we also explored the influence of inorganic anions in water and actual water medium on the rate of CIP removal. In addition, the ESR data proved that the main active substance in the reaction system was ·OH. The degradation intermediates were investigated, and the possible mechanism was proposed. Thus, this research provided a new solution for the treatment of antibiotic-containing wastewater.
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高影响因子
Nano Research
·
2021
·Vol. 14
·期 10
·3576-3584
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IF 8.897
Wei Chuanliang,Wang Yusheng,Zhang Yuchan,Tan Liwen,Qian Yi,Tao Yuan,Xiong Shenglin,Feng Jinkui
Lithium metal (Li) is believed to be the ultimate anode for lithium-ion batteries (LIBs) owing to the advantages of high theoretical capacity, the lowest electrochemical potential, and light weight. Nevertheless, issues such as uncontrollable growth of Li dendrites, large volume changes, high chemical reactivity, and unstable solid electrolyte interphase (SEI) hinder its rapid development and practical application. Herein a stable and dendrite-free Li-metal anode is obtained by designing a flexible and freestanding MXene/COF framework for metallic Li. COF-LZU1 microspheres are distributed among the MXene film framework. Lithiophilic COF-LZU1 microspheres as nucleation seeds can promote uniform Li nucleation by homogenizing the Li + flux and lowering the nucleation barrier, finally resulting in dense and dendrite-free Li deposition. Under the regulation of the COF-LZU1 seeds, the Coulombic efficiency of the MXene/COF-LZU1 framework and electrochemical stability of corresponding symmetric cells are obviously enhanced. Li-S full cells with the modified Li-metal anode and sulfurized polyacrylonitrile (S@PAN) cathode also exhibited a superior electrochemical performance.
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高影响因子
BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
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2021
·Vol. 38
·期 2
·265-272
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IF 1.232
Wang Jianfeng,Zhao Make,Lu Xiaoli,Gu Hongbing,Liu Baoquan
Glucose dehydrogenase, as an important biocatalyst, has been widely used in biosensors, especially in measuring blood glucose levels. The low stability of the enzyme limits its applications in clinics and industry. To improve the stability, graphene oxide nanoparticles were fabricated, characterized, and used to immobilize of glucose dehydrogenase. The nanoparticles were characterized by FTIR. The enzyme was covalently immobilized on the nanoparticles with the activation of glutaraldehyde. After optimizing the immobilization conditions, an immobilization yield of 92% and the activity recovery of 91% were achieved. The immobilized GDH was characterized and compared with the free enzyme. It showed 6.9-fold higher stability than that of the free enzyme after the immobilization. And after 25 cycles, the immobilized GDH remained 50% of the initial activity. These results indicated that the immobilization could broaden the applications of the GDH in the industry and clinic.
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JOURNAL OF ELECTRONIC MATERIALS
·
2021
·Vol. 50
·期 6
·3078-3083
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IF 1.938
Wu Wanyi,Wang Mengkun,Huang Huihui,Gu Wenxian,Yan Chengzhan,Chen Guang,Yin Dewu,Jin Huile,Wang Jichang,Wang Shun
In this work, hierarchically porous carbon spheres co-doped by iron and nitrogen were synthesized via in situ dehalogenation. The rich porous structure and relatively high specific surface area (210 m 2 /g) facilitate the formation of an ultra-fine Fe 2 N active phase and FeN 4 active centers within the carbon matrix. Transmission electron microscopy and X-ray photoelectron spectroscopy analysis further reveal the presence of a dominant Fe 2 N phase and minor FeN 4 bonds in the as-prepared Fe-N-C-pd-800 samples. Because of this, the oxygen reduction reaction (ORR) process can more readily take place on Fe 2 N than on FeN 4 , and the Fe 2 N phase enriched Fe-N-C-pd-800 carbon spheres exhibit a promising onset potential ( E onset =1.02 V) and half-wave potential ( E 1/2 =0.86 V) in alkaline media. In addition, Fe-N-C-pd-800 also shows excellent methanol resistance and long-cycling stability.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 29
·39199-39209
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IF 4.223
Peng Yecan,Ye Guirong,Du Yangliu,Zeng Lingyu,Hao Jiawen,Wang Shuangfei,Zhou Jinghong
This study focused on the feasibility of using Fe 3 O 4 /graphene oxide (FGO) nanocomposites as heterogeneous catalysts for the advanced treatment of real industrial wastewater. FGO nanocomposites with different graphene oxide (GO) ratios were synthesized by coprecipitating iron salts onto GO sheets in basic solution. The characterization of the resulting material structures and functionalities was performed using a range of analytical techniques. A low GO loading afforded a good Fe 3 O 4 nanoparticle dispersibility and resulted in a higher Brunauer–Emmett–Teller surface area and pore volume. The FGO nanocomposites and pure Fe 3 O 4 were used to treat papermaking wastewater in a heterogeneous photo-Fenton process. The results suggested that the nanocomposite designated FGO1 (GO loading of 25 mg) exhibits a higher photocatalytic efficiency than other FGO nanocomposites and pure Fe 3 O 4 . A maximum chemical oxygen demand degradation efficiency of 89.6% was achieved in 80 min with 1.5 g L −1 FGO1 at pH 3. The degradation of different pollutants present in wastewater was evaluated with the aid of gas chromatography–mass spectrometry and 3D excitation–emission-matrix analysis. Inductively coupled plasma atomic emission spectroscopy and magnetic measurements confirmed that the FGO1 nanocomposites possess a low iron leachability and a high reusability. Thus, a comprehensive advanced treatment of real industrial wastewater using a magnetic FGO catalyst is demonstrated.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 37
·期 2
·286-292
·
IF 1.307
Hu Tao,Yang Weiwei,Wang Cheng,Bu Yali,Jin Feng,Zhang Dongwen,Gu Min,Liu Wenhui,Liang Qinghua,Liu Ruiqing,Feng Xiaomiao,Ma Yanwen
Sodiumion batteries(SIBs) have attracted intensive attention as promising alternative to lithium-ionbatteries(LIBs) for large scale energy storage systems because of low cost of sodium, similar energy storage mechanism and the reasonable performance. However, it is still a great challenge to search and design a robust structure of anode materials with excellent cycling stability and high rate capability for SIBs. Herein, multilayer porous vanadium nitride (VN) microsheets are synthesized through a facile and scalable hydrothermal synthesis-nitrogenization strategy as an effective anode material for SIBs. The multilayer porous VN microsheets not only offer more active sites for fast Na + insertion/extraction process and short diffusion pathway, but also effectively buffer the volume change of anode due to more space in the multilayer porous structure. The large proportions of capacitive behavior imply that the Na + charge storage depends on the intercalation pseudocapacitive mechanism. The multilayer porous VN microsheets electrodes manifest excellent cycling stability and rate capability, delivering a discharge capacity of 156.1 mA·h/g at 200 mA/g after 100 cycles, and a discharge capacity of 111.9 mA·h/g at 1.0 A/g even after 2300 cycles with the Coulombic efficiency of nearly 100%.
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CELLULOSE
·
2021
·Vol. 28
·期 7
·4039-4051
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IF 5.044
Yang Jirui,Wang Xiaoqi,Shen Feng,Qi Xinhua
Pretreatment is a necessary process in biorefineries to overcome recalcitrance of biomass and enhance its conversion efficiency for further transformation. NaOH activation of Na 2 S 2 O 8 , which merges alkaline pretreatment and advanced oxidation processes (AOPs) into one process, was performed at room temperature (25 °C) within a short duration (60 min). High concentration of NaOH plays a critically important role in NaOH–Na 2 S 2 O 8 pretreatment, which not only selectively removed hemicellulose in the lignocellulosic feedstock, but also activated Na 2 S 2 O 8 to produce strong oxidative radicals, leading to disruption of lignin matrix. The surface area and porosity for the pretreated feedstock were significantly increased compared with those of the pristine counterpart. After pretreatment by 5.12 M NaOH and 0.85 M Na 2 S 2 O 8 , the maximum glucose yield of the feedstock was increased by 47.4% compared with that of pristine counterpart (60.3% vs. 40.9%). This study provides an effective and easily-realizable pretreatment method for the utilization of lignocellulosic biomass. Graphic abstract
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JOURNAL OF NANOBIOTECHNOLOGY
·
2021
·Vol. 19
·期 1
·1-19
·
IF 10.435
Li Yuzhan,Liang Luxin,Li Wu,Ashraf Umair,Ma Lin,Tang Xiangru,Pan Shenggang,Tian Hua,Mo Zhaowen
Background Cadmium (Cd) is amongst the most toxic heavy metals that severely affects crop growth, whereas application of nanoparticles (NPs) to negate the toxic effects of heavy metals could be an effective management approach. In the present study, the seeds of two fragrant rice varieties i.e., Yuxiangyouzhan and Xiangyaxiangzhan under normal and Cd stress conditions i.e., 0 and 100 mg L− 1 applied with four levels of ZnO NPs i.e., 0, 25, 50, and 100 mg L− 1.Results Seed priming with ZnO NPs had no significant effect on the seed germination (p > 0.05) however, it substantially improved the seedling growth and other related physiological attributes under the Cd stress. The mean fresh weight of the shoot, and whole seedling was increased by 16.92–27.88% and by 16.92–27.88% after ZnO NPs application. The root fresh weight, root-shoot length was also substantially improved under ZnO NPs treatment. Moreover, application of ZnO NPs induced modulations in physiological and biochemical attributes e.g., the superoxide dismutase (SOD) activity in root and shoot, the peroxidase (POD) activity and metallothionein contents in root were increased under low levels of ZnO NPs. The α-amylase and total amylase activity were improved by ZnO NPs application under Cd Stress. Besides, modulation in Zn concentration and ZnO NPs uptake in the seedling were detected. The metabolomic analysis indicated that various pathways such as alanine, aspartate and glutamate metabolism, phenylpropanoid biosynthesis, and taurine and hypotaurine metabolism were possibly important for rice response to ZnO NPs and Cd.Conclusion Overall, application of ZnO NPs substantially improved the early growth and related physio-biochemical attributes in rice. Our findings provide new insights regarding the effects of ZnO NPs on seed germination, and early growth of rice, and its potential applications in developing crop resilience against Cd contaminated soils.
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高影响因子
JOURNAL OF POLYMERS AND THE ENVIRONMENT
·
2021
·Vol. 29
·期 10
·3252-3262
·
IF 3.667
Aljohny Bassam Oud,Almaliki Abdullah Abdulaziz Ali,Anwar Yasir,Ul-Islam Mazhar,Kamal Tahseen
In this research work, a green method of using Saussurea costus extract for the synthesis of silver nanoparticles (AgNPs) is developed. Analysis of the synthesized AgNPs showed that the hydroxyl and carbonyl functionalities of the Saussurea costus extract are playing major roles in their synthesis. X-ray diffraction revealed that the AgNP has face-centered cubic crystal structure. Field emission scanning electron microscopy suggested that the AgNP nanoparticles has a spherical shape with sizes ranging ~ 45 ± 15 nm. Furthermore, these green synthesized AgNPs were applied in the catalysis as well as biomedical fields. AgNPs were embedded in a crosslinked thin polyvinyl alcohol sheet and repeatedly used in the 4-nitrophenol (4-NP) reduction for 8 times. A high activity was observed for the Saussurea costus extract synthesized AgNP (S.C./AgNP) where the rate constant was 0.441 min − 1 . The antibacterial studies on Escherichia coli , and Acinetobacter baumannii (gram negative) and Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA) (gram positive) bacterial strains showed a good potential of the S.C./AgNP in killing these pathogens at a concentration of 1 µg/ml.
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Advanced Fiber Materials
·
2021
·Vol. 3
·期 2
·138-146
·
IF 0
Li Chen,Ren Lipei,Zhang Chunhua,Xu Weilin,Liu Xin
Polypropylene (PP) membrane has been widely used in water purification and other fields owing to special pore structure, excellent mechanical properties and resistance to acids, alkalis and organic solvents. However, it is difficult for PP to introduce the hydrophilic chemical compositions for oil–water separation. Herein, superhydrophilic and underwater superoleophobic PP membranes were prepared by ALD for efficient gravity-driven oil–water separation. Owing to synergistic effect, oil contact angle of TiO 2 coated PP membrane under water can reach above 150°. Hence, TiO 2 coated PP membrane has great oil-repelling performance. Because of the superwetting property, TiO 2 coated PP membrane can easily separate oil–water mixture and have high separation efficiency (more than 95%). The outstanding recyclability and mechanical stability of TiO 2 coated PP membrane suggest the promising potential application in practical oil–water separation.
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