JOURNAL OF HAZARDOUS MATERIALS
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2021
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IF 10.588
Hailong Zhang,Jianying Qi,Fang Liu,Zhangxin Wang,Xiaoming Ma,Di He
Thallium (Tl) often enters the environment via mineral exploitation and utilization. The main restriction of Tl removal is the interference of high concentrations of coexisting ions in wastewater, therefore, enhancing the selectivity for Tl is essential to its treatment. Magnetic Prussian blue particles (Fe 3 O 4 @PB), an ion-sieving material with an open structure, were synthesized through a “one-pot” method at room temperature for the highly selective removal of Tl + . The removal percentage of Tl + was over 92% even when the concentration of coexisting ions (e.g. Zn 2+ , Cd 2+ , Cu 2+ , and Pb 2+ ) were 10,000 times higher than the initial concentration of Tl + . The maximal experimental removal capacity was 528 mg Tl/g Fe 3 O 4 @PB, and the removal percentage remained steady at pH 3–10. The high selectivity of Fe 3 O 4 @PB for Tl + is attributed to the fact that hydrated Tl + has a smaller hydrated diameter and a lower hydration free energy than other coexisting ions, while the rapid adsorption kinetics of Tl + results from the negative surface charge and the network of nanocapillaries of the Fe 3 O 4 @PB. Overall, a new low-cost material that is easy to synthesize and has superior Tl + removal capacity with extremely high selectivity for Tl + was obtained for effective magnetic removal of thallium from wastewater.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Jinjie Wang,Shuyi Ma,Jicun Ren,Jinxia Yang,Yi Qu,Derun Ding,Min Zhang,Guang Yang
Keratins are a group of cysteine-rich structural proteins found abundant in hair, wool, feathers, etc. In this work, a highly luminescent gold nanocluster (AuNCs-Ag@Keratin) was synthesized for the first time by using keratin as the template, followed by a simple modification with silver(I) ions. The prepared AuNCs-Ag@Keratin could exhibit dramatically enhanced red fluorescence (λ em = 725 nm), which was about 5-folds higher than that of common AuNCs@Keratin. The interactions of AuNCs with silver(I) ions were systematically characterized by fluorescence measurements, fluorescence correlation spectroscopy (FCS) and X-ray photoelectron spectroscopy (XPS). It was demonstrated that the “silver effect” could not only enhance the fluorescence intensity of AuNCs, but also improved the particles’ dispersion and stability. The as-prepared AuNCs-Ag@Keratin was applied to detect Hg 2+ in a wide detection range (2.44–2500 nM) and low detection limit (2.31 nM).
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2018
·
IF 3.412
Jingjing Luo,Xiaofeng Meng,Jianyu Su,Hang Ma,Wen Wang,Liming Fang,Huade Zheng,Yexia Qin,Tianfeng Chen
15,16-Dihydrotanshinone I (DI), a natural compound isolated from a traditional Asian functional food Salvia Miltiorrhiza Bunge, is known for its anticancer activity. However, poor solubility of DI limits its desirable anticancer application. Herein, polylactic-co-glycolic acid (PLGA) was functionalized with polyethylene glycol (PEG) and biotin to form copolymers PEG-PLGA (PPA) and biotin-PEG-PLGA (BPA). DI was encapsulated in copolymers PPA and BPA to obtain DI-PPA-NPs (NPs = nanoparticles) and DI-BPA-NPs, respectively. The particle size and its distribution, encapsulation efficiency, and in vitro releasing capacity of DI-BPA-NPs were characterized by biophysical methods. MTT assay was used to evaluate the antiproliferative activity of free DI, DI-PPA-NPs, and DI-BPA-NPs in human cervical cancer Hela cells. DI-BPA-NPs showed the highest cytotoxicity on Hela cells with an IC50 value of 4.55 ± 0.631 μM, while it was 8.20 ± 0.849 and 6.14 ± 0.312 μM for DI and DI-PPA-NPs in 72 h, respectively. The superior antiproliferative activity was supported by the fact that DI-BPA-NPs could be preferentially internalized by Hela cells, owing to their specific interaction between biotin and overexpressed biotin receptors. In addition, DI-BPA-NPs effectively inhibited Hela cell proliferation by inducing G2/M phase cycle arrest and decreasing the intracellular reactive oxygen species (ROS) level by 31.50 ± 2.29% in 5 min. In summary, DI-BPA-NPs shows improved antiproliferative activity against human cervical cancer as comparing with free DI, demonstrating its application potential in cancer therapy.
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PEPTIDES
·
2018
·
IF 2.851
Fengjing Jia,Yi Zhang,Jiayi Wang,Jinxiu Peng,Ping Zhao,Lishi Zhang,Haiyan Yao,Jingman Ni,Kairong Wang
Antimicrobial peptides (AMPs) are believed to be a promising class of antimicrobial agents against bacteria and fungi. To promote the clinical use of AMPs, their antimicrobial activity and susceptibility to protease degradation should be further improved. The antimicrobial peptide Jelleine-I was originally isolated from the royal jelly of honeybees ( Apis mellifera ) with a short sequence of PFKLSLHL-NH 2 (953.24 Da). Here, a series of halogenated derivatives of the antimicrobial peptide Jelleine-I were designed and synthesized. The results showed that the in vitro antimicrobial activity, antibiofilm activity and in vivo antimicrobial efficacy were enhanced 1-8-fold after halogenation. Additionally, the proteolytic stability of Jelleine-I was improved 10-100-fold by halogenation. Meanwhile, the halogenated derivatives retained negligible hemolytic activity and cytotoxicity. Among these derivatives, the antimicrobial activity and antibiofilm activity of chlorine-Jelleine-I (Cl-J-I), bromine-Jelleine-I (Br-J-I), and iodine-Jelleine-I (I-J-I) were better than those of fluorine-Jelleine-I (F-J-I). The stabilities of Br-J-I and I-J-I against the degradation of enzymes and the serum were better than those of F-J-I and Cl-J-I. In conclusion, this study may offer a useful strategy to enhance antimicrobial efficacy and proteolytic stability by halogenation. The halogenated derivatives Cl-J-I, Br-J-I and I-J-I may be considered as potential antimicrobial agents against microbial infection.
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MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 10
·1-6
·
IF 5.705
Ma Liang,Guo Ting,Pan Shuli,Zhang Yuhao
A fluorometric patulin (PAT) assay is presented that is based on the use of magnetic reduced graphene oxide (rGO) and DNase I. The fluorescence of the PAT aptamer labelled with 6-carboxyfluorescein (FAM) is quenched by magnetized reduced graphene oxide (rGO-Fe 3 O 4 ) due to fluorescence resonance energy transfer (FRET). However, in the presence of PAT, the labelled aptamer is stripped off from rGO-Fe 3 O 4 . The rGO-Fe 3 O 4 is then magnetically separated so that the fluorescence of free labelled PAT aptamer is restored. DNase I cannot hydrolyze the aptamer on rGO-Fe 3 O 4 , but it can cleave the free aptamer-PAT complex. This will release FAM and PAT which can undergo a number of additional cycles to trigger the cleavage of abundant aptamer. Recycling of DNase I-assisted target therefore leads to a strong amplification of fluorescence and consequently to an assay with low limit of detection. The detection limit for PAT is as low as 0.28 μg L −1 which is about 13 times lower than that without using DNase I. The method offers a new approach towards rapid, sensitive and selective detection based on an aptamer. Conceivably, it has a wide scope in that it may be applied to numerous other analytes if appropriate aptamers are available.
Schematic of a fluorometric assay based on the use of magnetic graphene oxide and DNase I. It was applied to the determination of patulin. DNase I was introduced for recycling amplification. The detection limit is about 13 times lower than that without using DNase I. Figure a contains poor quality of text in image. Otherwise, please provide replacement figure file.Thank you. I will provide the figure file.
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ACS Applied Materials & Interfaces
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2018
·
IF 8.097
Yu-Xia Li,Yu-Nong Ji,Meng-Meng Jin,Shi-Chao Qi,Shuai-Shuai Li,Ding-Ming Xue,Ming Bo Yue,Xiao-Qin Liu,Lin-Bing Sun
Here, we designed a double-solvent/host–guest redox combined strategy to construct Cu+ sites in metal–organic frameworks (MOFs) for the first time. As a proof of concept, a representative MOF MIL-100(Fe) with tunable valence states of cations was employed as the host. The combined strategy realizes selective introduction of Cu2+ precursors to the interior pores of MIL-100(Fe), remarkably minimizing the aggregation of Cu2+ and subsequently formed Cu+ species. Owing to the proper reducibility of in situ formed Fe2+ in the frameworks, controlled conversation of Cu2+ to Cu+ with ∼100% yield is achieved in the absence of any additional reducing agents. These characteristics make the obtained materials Cu+-modified MIL-100(Fe) highly active in selective CO adsorption. The CO adsorption capacity is up to 3.75 mmol·g–1 at 298 K and 1 bar, which is superior to all other Cu+-containing adsorbents reported so far such as CuCl/activated carbon (2.5 mmol·g–1), CuCl/γ-Al2O3 (1.0 mmol·g–1), and CuCl/SBA-15 (0.50 mmol·g–1). The same adsorbent also exhibits quite high selectivity of CO over N2, and the ideal adsorption solution theory selectivity reaches 424. The outstanding CO adsorption performance make the present adsorbents great potential in separation of CO from various mixtures.
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CHEMISTRY OF MATERIALS
·
2018
·
IF 9.89
Ying Liu,Fei Li,Quanlin Liu,Zhiguo Xia
All inorganic cesium lead halide CsPbX3 (X = Cl, Br, I) perovskite nanocrystals (NCs) are generally considered to be sensitive and even decompose when exposed to ambient humidity. Herein, we perform a well-controlled investigation of the effect of postsynthetic water treatment of the as-prepared CsPbX3 NCs on the photoluminescence quantum yields (PLQYs) and stability, and one can find that the surface defective layer of CsPbX3 NCs can be dissolved into water and we can further separate the supernatant CsPbX3 NCs hexane solution from the water, which improves the PLQYs of CsPbCl3, CsPbBr3, CsPbI3 from 5%, 69.3%, 68.1% to 78.5%, 95.5%, 91%, respectively. As a synergetic effect, a trace amount of residual water facilitated the hydrolysis of tetramethyl orthosilicate, leading to the formation of SiO2-coated CsPbX3 NCs with high stability. The stable green-emitting CsPbBr3/SiO2 composite is used as an example to combine with red K2SiF6:Mn4+ to fabricate the light-emitting diodes device on the blue InGaN chip, which displays wide color gamut (128% of National Television Standard Committee standard), providing the possibility for liquid-crystal display backlight utilization.
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Analytical Methods
·
2013
·Vol. 6
·期 5
·1517-1522
·
IF 1.855
Dong-Sheng Lin,Jia-Ping Lai,Hui Sun,Zhou Yang,Yue Zuo
In this paper, a fluorescein spirolactam derivative, ((E)-3′,6′-dihydroxy-2-((thiazol-2-ylmethylene)aminospiro[isoindoline-1,9′-xanthen]-3-one) (HTMIX), was synthesized and used as a turn-on fluorescence probe for the detection of silver ion in aqueous solution. The binding mechanism of HTMIX to Ag+ was evaluated using the Hildebrand–Benesi equation based on a 1 : 1 binding model with R = 0.9993. And the influence of sixteen common metal ions on the fluorescence intensities of HTMIX–Ag+ solution was investigated in detail. The results show that HTMIX exhibited high selectivity towards Ag+ in a 20% ethanol solution. The obtained fluorescence probe was used for the quantitative determination of Ag+ with a good linear range from 0.1 μM to 10 μM (R = 0.9969) and a satisfactory detection limit of 0.08 μM. In addition, the present probe has been further used for the detection of Ag+ in tap water, river water and lake water. And the accuracy of the results obtained by the proposed method was in good agreement with that obtained by flame atomic absorption spectrometry.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2015
·
IF 2.729
Meiling Wang,Zhengnian Chen,Yaomin Chen,Chunjin Zhan,Jianwei Zhao
Positively charged gold nanoparticles (AuNPs) were self-assembled onto the surfaces of 1-allyl-3-methylimidazolium chloride (AMIM-Cl) functionalized reduced graphene oxide sheets (RGO) here. The AMIM-Cl functionalized RGO (ILRGO) loaded with AuNPs (ILRGO@AuNPs) modified glass carbon electrodes (GCEs) possess larger effective specific surface areas which can favor the adsorption of more Sudan I into the working electrode . So the ILRGO@AuNPs composites were successfully used for the fabrication of a facile and sensitive sensor for the determination of Sudan I. And the prepared sensor exhibits a broad linear range for Sudan I spanned 4 orders of magnitude from 1.0 × 10 − 10 to 1.0 × 10 − 6 M and a detection limit as low as 5.0 × 10 − 11 M (S/N = 3). It is expected that this green sensor can be applied in the determination of other similar dyes.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Ling Wang,Ran Yang,Jianjun Li,Lingbo Qu,Peter de B. Harrington
In this work, a very sensitive electrochemical sensor for Sudan I was established based on nanohybrids of graphene-ZnSe quantum dots . Positively charged cetyltrimethyl-ammonium bromide (CTAB) functionalized graphene was used as a template-directed building block to self-assemble negatively charged ZnSe quantum dots (QDs). The hybrids of ZnSe-CTAB-graphene exhibited strong enrichment effect on Sudan I and gave superior electrocatalytic activity towards the oxidation of Sudan I. Applying differential pulse voltammetry (DPV), the peak current of Sudan I is proportional to its concentration in the range from 0.004 to 2.0 μM and 2.0 to 15.0 μM. This report is the first on applying graphene-ZnSe hybrids for electrochemical sensing.
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Asia-Pacific Journal of Chemical Engineering
·
2016
·Vol. 11
·期 2
·305-313
·
IF 0.728
Xing Li,Lei Bei,Zhi Sun,Kun Liu,Xu Zhang,Xiaozhao Han
The study aimed at investigating the addition effects of P, K, and micronutrient fertilizers on the permeability of N-nutrient fertilizer urea through a representative polymer membrane, which is of great importance in polymer-coated compound fertilizer. Specifically, the permeability of urea through polystyrene membrane was determined experimentally at the nominal temperature of 298 K using the Ussing chamber method for fertilizer solutions of urea–water, urea–NaH 2 PO 4 –water, urea–Ca(H 2 PO 4 ) 2 –water, urea–KCl–water, and urea–NaCl–water. The experimental data showed that the addition effects of NaH 2 PO 4 , KCl, and NaCl on urea permeability were pronounced and could be promotion or suppression depending on the amounts added. The variation of urea permeability with additive concentration could be explained by the ‘solution–diffusion’ model, suggesting that the specific intermolecular and interionic interactions in the permeation solution were an important factor determining the permeability. Using the saturated urea–water solution as basis, the addition of saturated KCl increased the urea permeability by 2.5 times, while the addition of saturated Ca(H 2 PO 4 ) 2 and NaH 2 PO 4 decreased the permeability by 41% and 76%, respectively. © 2016 Curtin University of Technology and John Wiley & Sons, Ltd.
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JOURNAL OF BIOLOGICAL CHEMISTRY
·
2017
·Vol. 292
·期 12
·4789-4800
·
IF 4.125
Yun-Bin Han,Liu-Qing Chen,Zhuo Li,Yu-Meng Tan,Yan Feng,Guang-Yu Yang
Endoglycoceramidases (EGCases) specifically hydrolyze the glycosidic linkage between the oligosaccharide and the ceramide moieties of various glycosphingolipids, and they have received substantial attention in the emerging field of glycosphingolipidology. However, the mechanism regulating the strict substrate specificity of these GH5 glycosidases has not been identified. In this study, we report a novel EGCase I from Rhodococcus equi 103S (103S_EGCase I) with remarkably broad substrate specificity. Based on phylogenetic analyses, the enzyme may represent a new subfamily of GH5 glycosidases. The X-ray crystal structures of 103S_EGCase I alone and in complex with its substrates monosialodihexosylganglioside (GM3) and monosialotetrahexosylganglioside (GM1) enabled us to identify several structural features that may account for its broad specificity. Compared with EGCase II from Rhodococcus sp. M-777 (M777_EGCase II), which possesses strict substrate specificity, 103S_EGCase I possesses a longer α7-helix and a shorter loop 4, which forms a larger substrate-binding pocket that could accommodate more extended oligosaccharides. In addition, loop 2 and loop 8 of the enzyme adopt a more open conformation, which also enlarges the oligosaccharide-binding cavity. Based on this knowledge, a rationally designed experiment was performed to examine the substrate specificity of EGCase II. The truncation of loop 4 in M777_EGCase II increased its activity toward GM1 (163%). Remarkably, the S63G mutant of M777_EGCase II showed a broader substrate spectra and significantly increased activity toward bulky substrates (up to >1370-fold for fucosyl-GM1). Collectively, the results presented here reveal the exquisite substrate recognition mechanism of EGCases and provide an opportunity for further engineering of these enzymes.
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