COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Mingming Sun,Wei Guo,Jiesheng Tian,Xin Chen,Qiuyu Zhang
Gold nanoflowers (Au NFs) have received great attention for surface-enhanced Raman scattering (SERS) applications, due to the high surface area, availability of conjugation sites on surface and the localized surface plasmon resonance . However, their further application is much hampered by the complicated and time-consuming synthesis process, which remains better responded. Herein, we propose a novel & straightforward interface-modified reverse microdroplet strategy to configure homogeneously dispersed Au NFs within two hours, where Au 3+ was reduced by excess aniline as two-in-one medium of reductant and solvent. It is demonstrated that the reaction system is robustly directed by the dynamic built-in reaction interface, thanks to the capping effect of the in-situ formed polyaniline (PANI) and polyvinyl pyrrolidone (PVP). It is further identified that the final morphology of Au NFs is strongly determined by the nucleation & growth rates. Consequently, such a well-tailored microstructure endows the Au NFs with sound performance for SERS applications. When using methylene blue (MB) as a molecular probe , a high SERS enhancement factor above 10 5 is delivered. This work provides a feasible interface-assisted methodology to investigate multi-level structures, and sheds light toward simply advancing versatile nanomaterials for broad applications.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 4
·2080
·
IF 6.208
Zhaoqian Fan,Yukun Qin,Song Liu,Ronge Xing,Huahua Yu,Kecheng Li,Pengcheng Li
The exploration of novel, environmentally friendly, and efficient nematicides is essential, and modifying natural biomacromolecules is one feasible approach. In this study, 6-O-(trifluorobutenyl-oxadiazol)-chitosan oligosaccharide derivative was synthesized and characterized by FTIR, NMR, and TG/DTG. Its bioactivity and action mode against root-knot nematodeM. incognitawere estimated. The results show that the derivative shows high nematicidal activity against J2s, and egg hatching inhibitory activity at 1 mg/mL. The derivative may affect nematode ROS metabolism and further damage intestinal tissue to kill nematode. Meanwhile, by synergism with improving crop resistance, the derivative performed a high control effect on the nematode with low phytotoxicity. These findings suggested that chitosan oligosaccharide derivatives bearing fluoroalkenyl groups are promising green nematicides.Keywords:chitosan oligosaccharide;nematicide;Meloidogyne incognita;trifluorobutenyl group
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Advanced Materials Technologies
·
2022
·Vol. 7
·期 6
·2101131
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IF 8.856
Cong Huang,Zhuang Hao,Ziran Wang,Hao Wang,Xuezeng Zhao,Yunlu Pan
An ultraflexible and transparent graphene-based field-effect transistors (GFET) wearable nanosensor is presented for detection of body fluid-biomarkers. The nanosensor is functionalized with a receptor that can specifically bind with the biomarker, resulting in a detectable change in the carrier concentration of the graphene. After recovery from 100 cycles of deformations (bending at radii 175 µm, folding at 150 ° , and shrinking at 50%), no visible mechanical damage is observed, and electrical properties of the nanosensor are also highly consistent. L-cysteine, associated with various diseases, is chosen as the biomarker to demonstrate the detection capability of the sensor. The nanosensor is capable of consistently and reliably detecting L-cysteine with a limit of detection of 0.022 × 10 −6 m in undiluted human sweat and 0.043 × 10 −6 m in artificial tears. The sensor is fabricated from the 1 µm transparent polyethylene glycol terephthalate substrate and WO 3 /Au/WO 3 electrode (transparency of 81%), and it can be mounted on the eyeball in tear detection without visual influence. These results demonstrate that the ultraflexible and transparent GFET wearable nanosensor can potentially be helpful in medical detection applications.
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Journal of Cleaner Production
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2022
·
IF 11.072
Lei Zhang,Xuexiu Jia,Yusen Ai,Renliang Huang,Wei Qi,Zhimin He,Jiří Jaromír Klemeš,Rongxin Su
Cellulose nanocrystals (CNCs) are usually prepared by sulphuric acid hydrolysis in industrial production, resulting in a large amount of alkaline and water consumption. In this paper, three acid-CNCs separation methods, including gravity settling, centrifugation and microfiltration , are used to directly separate sulphuric acid from hydrolysate mixture to reduce alkaline and water consumption. Microfiltration was selected as the best method for acid-CNCs separation. Using microfiltration, the highest sulphuric acid recovery ratio was about 65.0%, with an acid concentration range of 8–10 wt% in the pilot-scale CNCs production. Continuous centrifugation was introduced to replace gravity settling to separate CNCs from the neutralised mixture for faster production and reducing water consumption. The consumption of alkaline and water decreased by 63.0% and 68.0%, and the cost was reduced by 26%. The result of life cycle assessment (LCA) showed that the process with acid-CNCs separation using microfiltration achieved a reduction of 33.4% in aquatic ecotoxicity, 38.1% in terrestrial ecotoxicity , 47.9% in aquatic acidification, 55.8% in aquatic eutrophication , 40.0% in global warming potential and 47.8% in non-renewable energy consumptions. This study provided a promising approach for separating sulphuric acid from hydrolysate mixture and reducing consumption of alkaline and water. Such clean and economic process has great potential in the industrial production of CNCs.
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ACS Applied Polymer Materials
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2022
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IF 4.855
Yingjun Yang,Xiaoqiang Hou,Shufang Ma,Siyuan Huang,Jingyi Chen,Zejian Fang,Guanjian Nie,Bingshe Xu,Christophe A. Serra,Shukai Ding
AIEgens have attracted intensive interest because of the unusual fluorescence feature. Although AIEgen-based materials have been developed for responding to the diverse ex-stimuli, such as mechano-, electro-, and thermal-stimuli, the practical application of AIEgen-based thermoluminescence is hampered for the following reasons: (1) high cost attributed to the complicated chemical modification, (2) low contrast and responsiveness resulting from the chromophoric property of the thermal functional group. In this contribution, a facile encapsulation technology-based strategy without any chemical modifications is developed to form the encapsulated TPE nanogels for the preparation of the AIEgen-based thermoluminescence. Thanks to the coexistence of the liquid and solid phases, the nanogel-based AIEgens can not only attain the transparent feature but also a reversible transformation between the single-molecule and aggregated state by ex-thermal stimuli. In the nanogel, the two aggregated states of TPE molecules are observed that result from being tangled by poly-TPGDA and from being self-assembled, respectively. Furthermore, the nanogels prepared at different temperatures demonstrate the controllable fluorescence intensity. The higher preparation temperature results in more aggregated TPE and higher fluorescence intensity. Finally, the nanogels are easily formed into the transparent film thermometers because of their flowability, which shows a switchable and stable fluorescence by ex-thermal stimuli. The transparent film thermometer demonstrates high potential in anticounterfeiting technology and biological imaging.
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JOURNAL OF POWER SOURCES
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2022
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IF 9.794
Hongliang Xie,Zhiyuan Chen,Peng Chu,Jie Wang,Zehao Li,Hailei Zhao
Liquid metal battery (LMB) with low cost, excellent cycle performance and flexible scalability is developed as a promising solution for large-scale energy storage. However, the high melting point of the electrolyte necessitates an elevated operating temperature, which provokes aggravated hermetic seal and corrosion issues, seriously inhibiting the advancement of LMBs. Herein, we elaborately design a novel LiCl–LiBr–KBr electrolyte system based on the mass triangle model to overcome this obstacle. The LiCl and LiBr components can provide required lithium ionic conduction, while the KBr plays a dual role of decreasing the melting point and suppressing metal lithium dissolution. The designed LiCl–LiBr–KBr (33:29:38 mol%) electrolyte possesses low melting point (T m = 327 °C), and high ionic conductivity (1.573 S cm −1 at 420 °C), which enables the Li||Bi battery to work efficiently at 420 °C with high energy efficiency (83%), excellent rate capability, superior cycling stability and freeze/thaw performance. This represents an 80–130 °C decrease in operating temperature compared to most reported LMBs. The unique performance combination together with its low cost makes the designed electrolyte extremely attractive for low-temperature LMB.
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Advanced Optical Materials
·
2022
·Vol. 10
·期 14
·2102709
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IF 10.05
Yinghua Liu,Jianfeng Zeng,Qing Li,Minqian Miao,Zhuorun Song,Min Zhao,Qingqing Miao,Mingyuan Gao
Developing smart molecular probes for assisting surgeons to precisely detect cancerous tissues and to completely remove all of them during the surgery is urgently required. Conventional fluorescent probes allow for tumor detection but with limited signal-to-noise ratio. Herein, an aminopeptidase N/CD13 (APN)-activated chemiluminescent probe (APN-ACLP) is reported for sensitive imaging and precise resection of malignant tumors. The APN-ACLP probe is based on acryl-substituted phenoxy-dioxetane that is coupled with an APN-cleavable substrate via a self-immolative linker. Upon activation by APN through specific hydrolysis reaction, APN-ACLP generates spontaneously chemiluminescence signal, which offers a possibility to sensitively search tumors by simply spraying APN-ACLP on the suspicious sites. Animal imaging studies reveal that a sufficient signal contrast between the cancerous tissues and the normal counterparts can be achieved within 5 min, which can allow for rapid detection and surgical resection of tumors, particularly tiny metastatic lesions in mice model, under the guidance of chemiluminescence imaging, well manifesting its potential for image-guided surgery of malignant tumors.
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Journal of Materials Chemistry B
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2022
·Vol. 10
·期 40
·8274-8281
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IF 7.571
Yahui He,Zheng Zhou,Yuting Huang,Wenxiang Zhu,Ning He,Xiaolong Zhu,Xiaoxiao Han,Hairong Liu
The limited availability of bioinks has hindered the application of 3D bioprinting to tissue engineering, and bacterial infection is a serious threat to these applications. Aiming to solve this problem, a novel ε-poly-L-lysine (EPL)-derived antibacterial bioink has been developed for 3D bioprinting and tissue-engineering applications. Three glycidyl methacrylate (GMA)-modified EPL products, EPLGMA-1, EPLGMA-2, and EPLGMA-3, were prepared by reacting 3, 4, and 5 mL GMA with 5 g EPL, respectively. EPLGMA-1, EPLGMA-2, and EPLGMA-3 were photocurable and their corresponding photo-crosslinked hydrogels, EPLGMA-1H, EPLGMA-2H, and EPLGMA-3H, all exhibited very high antibacterial rates, good biocompatibility, good degradability, and promising mechanical properties. After EPLGMA-1H, EPLGMA-2H, and EPLGMA-3H with encapsulated chondrocytes were incubated for 4 weeks, EPLGMA-3H was the best one among them for tissue-engineering applications due to its most efficient tissue regeneration. Carrying chondrocytes, the EPLGMA-3 solution was printed into hydrogel products with high-fidelity shapes and high cell viability using a projection-based 3D bioprinter. Following the implantation of chondrocyte-loaded EPLGMA-3H samples into nude mice for 4 weeks, cartilage-like tissue was regenerated, suggesting that EPLGMA-3 is a promising antibacterial bioink for 3D bioprinting and tissue-engineering applications.
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高影响因子
Nanoscale
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2022
·Vol. 14
·期 17
·6465-6470
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IF 8.307
Zhixiang Li,Xueyan Feng,Wenping Hu,Lele Li
Apoptosis plays an important role in the life cycle of multicellular organisms. The development of techniques for sensitive monitoring of apoptosis-related key molecules can be used to assess not only disease progression but also its therapeutic interventions. However, there is still a lack of an imaging probe amenable for simultaneously detecting multiple biomarkers during drug-induced apoptosis. Herein, a novel activatable DNA nanodevice was designed to image apoptosis-related dual proteins in real time. The turn-on and specific recognition properties of our probe allow the spatially selective detection of apoptotic-related marker cytochrome c and apurinic/apyrimidinic endonuclease 1 in living cells. We demonstrated that the DNA nanodevice has the ability to monitor apoptosis and evaluate the efficacy of apoptosis-related drugs, which potentially can be used as a tool to evaluate the molecular mechanism of apoptosis regulation or to screen apoptotic drugs.
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JOURNAL OF NUTRITIONAL BIOCHEMISTRY
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2022
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IF 6.117
Hui-jian Chen,Xi-yue Yan,Ao Sun,Li Zhang,Jing Zhang,You-e Yan
Obesity and metabolic disorders are threats to human health . Extracellular matrix (ECM) is an important member of adipose microenvironment . ECM remodeling contributes to obesity and insulin resistance, but the roles of every single ECM component is still not fully understood. We observed glucose and lipids metabolic disorders in high-fat diet (HFD)-fed mice and humans with obesity. Higher levels of inflammatory factors and hormones existed in serum of HFD-fed mice. Multiple collagens , laminins , fibronectin , nidogen , and Hspg2 were upregulated in obese white adipose tissue (WAT) from mice and humans. These effects were stronger in subcutaneous WAT than visceral WAT in mice, but the fat depot difference was reversed in humans. The ECM structure and the morphology of adipocytes seeded on ECM were changed in the HFD group. In human visceral WAT, ECM genes showed positive correlations with blood lipids and glucose. In vitro , collagen I/IV and LAMA4 proteins showed similar changes with C/EBPα during the differentiation of adipocytes. Macromolecular crowders (MMC) promoted partial collagen and non-collagen gene expression. Oleic acid (OA) and MMC upregulated collagen I/IV and LAMA4 proteins, and the effects of MMC were stronger than that of OA. Moreover, MMC promoted the differentiation of adipocytes, but OA increased the size of lipid droplets . Positive correlations were observed between ECM genes and adipogenesis-related genes in adipocytes. In conclusion, some obesogens (such as HFD) induce ECM remodeling, and the upregulation of ECM components is closely related to adipogenesis , suggesting that adipose ECM deposition is an indicator of obesity and metabolic disorders.
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SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Haiyan Zhang,Fei Feng,Yangyang Zhao,Bin Zhao,Lei Li,Dan Zheng,Xinxin Li
Increasing the aspect ratio of the microchannels of microfabricated gas chromatographic columns (μGCCs) can allow analytes to quickly reach equilibrium between the stationary phase and mobile phase , which helps improve their separation performance. In this paper, an all-silicon microfabricated gas chromatographic column (AS-μGCC) with a high aspect ratio was proposed and fabricated using deep reactive-ion etching (DRIE) and silicon direct bonding. Two AS-μGCCs with the lengths of 2 m and the aspect ratios of 6.6 (100 µm-width × 660 µm-depth) and 25 (30 µm-width × 750 µm-depth) were successfully fabricated. The effects of different aspect ratios on the column efficiency of AS-μGCCs were studied. A separation experiment showed that the column efficiency of the AS-μGCC with an aspect ratio of 25 (AS-μGCC-25) was 12 times higher than that of the AS-μGCC with an aspect ratio of 6.6 (AS-μGCC-6.6). The column efficiency of the AS-μGCC-25 was 1961 plates/m, and a heavy hydrocarbon mixture (C8–C20) could be separated using AS-μGCC-25 within 4.5 min
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FOOD CHEMISTRY
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2022
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IF 9.231
Ying Wan,Jian Li,Jitong Ma,Yanan Li,Ren Wang,Zhengxing Chen,Tao Wang
In this study, co-assembled protein-polysaccharide complexes (ZCs) were prepared by fixing zein nanoparticles at the fibrillar carboxymethyl cellulose (CMC) by pH-driven anti-solvent precipitation. The complexation boosted the dispersity of zein from 17.3% to 88.6%. Scanning electron microscopy and atomic force microscopy confirmed the formation of network structures where the fibrous polysaccharides inserted into the interval of granular proteins. Circular dichroism spectrum, fluorescence spectrum, and X-ray diffraction verified the electrostatic interaction pattern between zein and CMC. Besides, the ZCs presented favorable amphiphilic properties, and the electrostatic interaction between zein and CMC can be fine-tuned by the substitution degree (DS) of carboxymethyl in CMC. Therefore, the Pickering emulsions stabilized by ZCs had controllable size and long-term stability using DS as a stimulus. Our study offers a novel strategy developing bio-based materials as novel stabilizers of Pickering emulsions.
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