JOURNAL OF NANOBIOTECHNOLOGY
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2025
·Vol. 23
·期 1
·1-21
·
IF 12.6
Zhang Fenglan,Wang Tianyi,Wang Wenqiao,Lv Yaqian,Qu Yingshan,Liu Danping,Sun Xiaoyue,Kong Xiaoying,Wang Changyuan,Shi Jinsheng
As an important component of sunscreen products for sensitive skin, the potential damage mechanism of ZnO nanoparticles on skin surface with barrier structure or function defect caused by Cutibacterium acnes (C. acnes) has not been elucidated, which poses a serious challenge for reasonable selection of sunscreen products for acne-infected skin. In this work, we demonstrated for the first time that C. acnes induced significant changes in the membrane permeability and intracellular pH of fibroblasts through lipase up-regulation and lipid peroxidation, promoting endocytosis and ionization of ZnO NPs. High amounts of Zn2 + further delayed acne wound healing and aggravated scar hyperplasia by intervening matrix metalloproteinase-9 (MMP-9) and TGF-β1/Smad pathway. MMP9 was confirmed to be the key target of ZnO in delaying acne wound healing by the wound regulatory effects of MMP9 agonist and MMP9 inhibitor. In summary, this work clarified the interaction mechanism between ZnO NPs and acne skins, providing guideline for the application of physical sunscreens for special skins.Graphical abstract
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yapeng Li,Qinghong Pan,Huiting Shi,Youyou Du,Ailing Yang,Da-Peng Yang
The quantitative determination of cholesterol in foods, drugs, and biological fluids holds significant importance due to its potential health risks. Herein, a self-powered photoelectrochemical (PEC) sensor was developed for cholesterol detection. The photoelectrochemical system was constructed by modifying fluorine-doped tin oxide (FTO) electrodes with ZnO/C (serving as the photoanode) and iron-modified CuBi 2 O 4 (denoted as CBFO, functioning as the photocathode) through a controlled deposition process. To enhance detection selectivity, molecularly imprinted polymers (MIPs) were electrodeposited on the photocathode surface. The optimized sensor exhibited a linear detection range of 1–1000 nmol L −1 and a detection limit of 0.26 nmol L −1 (S/N = 3). Practical application of the sensor for cholesterol detection in milk samples demonstrated satisfactory recovery rates (98.6 %–107 %) with relative standard deviations (RSD) ranging from 2.38 % to 4.25 %. These results underscore the potential of this self-powered PEC sensor as a robust platform for rapid and accurate cholesterol determination in food products, pharmaceuticals, and environmental samples.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2017
·Vol. 28
·期 1
·1-8
·
IF 2.325
Wang Shilei,Wu Jie,Yang Hao,Liu Xiangyu,Huang Qiaomu,Lu Zhong
Dental caries is a widespread disease mainly caused by the anaerobic oral pathogen Streptococcus mutans ( S. mutans ). Ag/ZnO nanocomposite is an efficient antibacterial agent because of its high antibacterial activity and low cytotoxicity. In this study, rod-like Ag/ZnO nanocomposite was synthesized through a deposition-precipitation method and characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. The activity of Ag/ZnO nanocomposite against S. mutans was evaluated by determining the minimal inhibitory concentration, minimum bactericidal concentration and growth inhibition curve. The results showed that Ag/ZnO nanocomposite displayed higher activity against S. mutans compared with pure ZnO nanorods. Moreover, the antibacterial mechanism was investigated by determining the bacterial membrane potential, release of K + , intracellular reactive oxygen generation and lipid peroxidation. Disruption of membrane function and oxidation of biomacromolecules played important role in the antibacterial action of Ag/ZnO nanocomposite. This work proposes a potentially effective dental antibacterial agent against the dental caries-causing S. mutans .
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Journal of CO2 Utilization
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2022
·
IF 8.321
Xin Zong,Yingmin Jin,Yumeng Li,Xuebai Zhang,Shiji Zhang,Haijiao Xie,Jinqiu Zhang,Yueping Xiong
Electrochemical CO 2 reduction (ECR) is a promising approach to realize carbon neutral and energy sustainability , which is still impeded by the low selectivity and activity for application. Defect engineering of electrocatalysts , especially oxygen vacancy introduction into metal oxide materials has been proved to be an effective strategy to satisfy thermodynamic condition and improve kinetics for ECR. Herein, we synthesize oxygen vacancy-enriched ZnO nanoparticle catalysts for efficient ECR through electrospinning technique using particular precursor. Characterizations reveal that the utilization of Zn(CH 3 COO) 2 precursor contributes to the generation of oxygen vacancies in ZnO catalysts which enhances CO 2 adsorption and stabilizes the intermediate. In a flow cell configuration, a current density of 150 mA cm −2 and a CO Faradic efficiency > 80% can be obtained for ZnO nanoparticle catalysts (p-ZnO-800), which is meaningful for industry.
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Nanomaterials
·
2018
·Vol. 8
·期 10
·835
·
IF 3.504
Jiaqi Chen,Shaolong Huang,Yaojia Long,Jiahao Wu,Hui Li,Zhao Li,Yu-Jia Zeng,Shuangchen Ruan
Photocatalysis is a green technique that can convert solar energy to chemical energy, especially in H2production from water splitting. In this study, ZnO and red phosphorus (ZnO/RP) heterostructures were fabricated through a facile calcination method for the first time, which showed the considerable photocatalytic activity of H2evolution. The photocatalytic activities of heterostructures with different ratios of RP have been investigated in detail. Compared to bare ZnO, ZnO/RP heterostructures exhibit a 20.8-fold enhancement for H2production and furthermore overcome the photocorrosion issue of ZnO. The improved photocatalytic activities highly depend on the synergistic effect of the high migration efficiency of photo-induced electron–hole pairs with the inhibited charge carrier recombination on the surface. The presented strategy can also be applied to other semiconductors for various optoelectronics applications.Keywords:photocatalysis;H2evolution;red P;ZnO;heterostructure
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POLYMER TESTING
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2021
·
IF 4.282
Youmei Du,Dequan Ma,Jie Mao,Jianqi Yao,Qin Ma,Jing Lu,Faliang Luo,Chunhui Luo,Lei Li
In the current work, the polypropylene composites filled with a M-T-ZnOw@Ag filler with antibacterial and antistatic properties was firstly synthesized. The composites and the fabricated nanocomposites were characterized using SEM, TEM, XRD, FTIR and XPS techniques. With the addition of M-T-ZnOw@Ag, the antibacterial and antistatic properties of composite materials are greatly improved by the synergistic effect of AgNPs and T-ZnOw. When the filler content is 10 wt%, the antibacterial activity of the composite material against Gram negative ( Escherichia coli ) and Gram positive ( Staphylococcus aureus ) bacterial were 100%. And the surface resistivity was reduced to 5.5 × 10 10 Ω, fell by nearly 7 orders of magnitude compare with the neat PP. Furthermore, the composites showed better mechanical properties . The maximum impact strength of the composites is 56.3% higher than the neat PP. We believe the composite material with antibacterial and antistatic properties could greatly expand the application range of polypropylene materials.
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TALANTA
·
2022
·
IF 6.556
Haohua Yang,Xueqi Zhao,Ziwei Zhang,Pinyi Ma,Xinghua Wang,Daqian Song,Ying Sun
SPR is a mature optical biosensor technology for detecting biomolecular interactions without fluorescence or enzyme labeling. In this paper, we acquire a sensitive SPR biosensor based on [email protected] nanomaterial , and the classical sandwich strategy using biotin-streptavidin for secondary signal amplification system was used to detect human IgG (hIgG). Nano-zinc oxide (ZnO) has the dual characteristics of nanocomposite and traditional zinc oxide, with large specific surface area and high chemical activity. Besides, the gold-coated ZnO nanocrystals improve the optical properties of ZnO and enlarge the loading capacity with better biocompatibility. Therefore, a sensing platform based on [email protected] nanomaterial was constructed on gold film modified with mercaptan. Meanwhile, the biotin-avidin system in SPR sensor field has been rapidly developed and applied. Due to the highly selection of streptavidin (SA) and biotin interact with each other, GNRs-SA-biotin-Ab 2 (GSAB-Ab 2 ) were constructed to obtain the secondary enhancement of SPR signal. The influences of experimental conditions were also discussed. With optimal experimental conditions, introducing GSAB-Ab 2 conjugate combined with a sandwich format, the resulting SPR biosensor provides a favourable range for hIgG determination of 0.0375–40 μg mL −1 . The minimum detection concentration of hIgG that can be obtained by this method is approximately 67-fold lower than the conventional SPR sensor based on gold film. The sensitivity of SPR biosensor is significantly improved in a certain range.
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JOURNAL OF MOLECULAR STRUCTURE
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2020
·
IF 2.463
Jing Liu,Weiyan Sun,Jie Bai,Chunping Li
Nitrogen-enriched carbon nanofibers carried Sn and Zn bimetallic composites with outstanding storage capacity and superior mechanical strength were facilely fabricated by electrospinning technology, amidoximation reaction modified polymer fiber, ion coordination technique introduced Zn 2+ and carbonization of composite nanofibers. The introduction of amidoxime groups not only enhanced the coordination ability with Zn 2+ , but also increased the content of nitrogen element. In addition, due to the different thermal stability of amidoxime groups, the regulation of different types of nitrogen content can be achieved by changing the carbonization temperature, and the influence of nitrogen on the electrochemical performance was explained. At the same time, due to the role of carbothermal reduction , tin in different valence ratios was obtained and its contribution to the energy storage performance of supercapacitors was explored. Benefiting from high nitrogen-enriched level, mutation between Sn 2+ and Sn 4+ oxidation state and synergistic mechanism of ZnO-SnO x bimetal, the prepared composite had a high specific capacitance of 810.89 F g −1 at a current density of 0.5 A g −1 , outstanding cycling stability of 119% over 5000 cycles in 4 M KOH electrolyte. What’s more, we conducted a two-electrode test with the energy density of 50 Wh kg −1 at a power density of 374 W kg −1 . In consequence, this novel design is believed to have great potential in high energy and power density of energy storage devices in the future.
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APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Xiangjia Liu,Jin Li
In this study, a ZnO/NiS@NiO/rGO (ZNNG) composite was characterized using X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), and scanning electron microscopy (SEM). Compared with simple ZnO, ZNNG exhibited stronger green emissions, but no ultraviolet (UV) emission peak was observed. Through a comprehensive analysis of ultraviolet–visible (UV–vis) absorption spectra, Mott Schottky (MS) plots, electron paramagnetic resonance (EPR) spectra, and X-ray photoelectron spectroscopy (XPS) results, it was proved that the stable green emissions of ZnO and its composites originated from the quenching of electrons between Zn interstitial ( Zn i ) and surface oxygen defects. The introduction of NiS@NiO caused the conduction band (CB) and valence band (VB) of ZnO to change to lower energy states, effectively increasing the absorption intensities of ZnO in the visible light, while introducing numerous oxygen-related defects on the surface of ZnO. Further addition of rGO effectively promoted the migration of electrons from the CB to the Fermi energy (E f ). These effects effectively increased the green emission of ZnO and reduced the UV emission. Finally, a proper mechanism for the near-zero band gap NiS@NiO/rGO that can significantly enhance the green emission of ZnO was proposed.
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Journal of Materials Chemistry C
·
2025
·
IF 5.1
Yuanjie Teng,Jie Li,Yantao Lou,Xingchen Zhang,Ze Wang,Naiwen Zhang,V. Balasubramani,Tianyu Hu,Zaifa Pan
Surface-enhanced Raman scattering (SERS) offers single-molecule sensitivity, but its practical use is constrained by the high cost and instability of noble-metal substrates. Semiconductor based SERS substrates are more stable and scalable, but typically suffer from weak charge transfer due to wide band gaps. Here we report a rare-earth doping strategy to boost the SERS activity of wide-band-gap ZnO. By introducing Er3+ with multielectron 4f orbitals into Zn1−xErxO (x = 0–8 mol%), the carrier density was simultaneously increased and new defect states were created that collaboratively enhance electromagnetic and chemical contributions. The optimized Er3+-doped ZnO substrate enables sensitive and reproducible detection of rhodamine 6G, achieving a detection limit of 2.4 × 10−8 M, an enhancement factor of 1.73 × 105, and excellent uniformity (RSD = 1.39%). Mott–Schottky analysis confirms carrier density increase upon Er doping, while DFT calculations attribute the dominant contribution to Er d-states and the introduction of 4f-induced surface defect levels that promote charge transfer. This work establishes rare-earth doping as an effective route to engineer semiconductor based SERS substrates and offers a mechanistic framework for designing non-metal SERS systems with synergistic electromagnetic and chemical enhancement.
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高影响因子
NANO
·
2019
·
IF 1.293
Chol-Nam Ri,Chol-Jun Kim,Song-Gol Kim,Myong-Hak Kim
The composite oxide additive containing Mn, Ni, Cr and Co elements for the ZnO varistor was successfully synthesized through the low-temperature combustion synthesis approach. The combustion reaction was carried out using nitrate mixtures of Mn, Ni, Cr and Co as oxidants and hydrazine as fuel. Herein, hydrazine acts as a bidentate bridge ligand, and it forms a complex with metal nitrate. Controlling the pH value of reactant solution by adding the hydrazine had a considerable effect on the combustion characteristics of the precursor and the final synthesized powder properties. The results of the XRD, FT-IR, SEM and TEM analysis indicated that the suitable pH value for synthesizing the composite additive powder with fine grain size and good crystallinity was 7. The precursor prepared at pH = 7 exhibited steady and slow combustion characteristics, and its yield rate achieved ca. 100%. With this method, the composite additive fine powder suitable for improvement of the electrical characteristics of ZnO varistor can be synthesized simultaneously on a large scale.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Jinyu Huang,Jiaxi Zhou,Zhenhua Liu,Xuejin Li,Youfu Geng,Xiaoqing Tian,Yu Du,Zhengfang Qian
ZnO nanorods doped by different amount of Au and Pd were successfully synthesized via one-step microwave-assisted hydrothermal method. The structure, morphology and composition of the as-synthesized products were characterized by X-ray diffraction (XRD), field-emission electron microscopy (FESEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). Gas sensors based on ZnO and Au/Pd-doped ZnO nanorods were fabricated and their gas sensing properties were tested for various gases. The results indicate that the incorporation of Au and Pd elements can greatly enhance the gas sensing properties of ZnO sensors. Specifically, the sensor based on 2.0 wt% Au-doped ZnO exhibits the highest response, quickest response and recovery characteristics, best selectivity, low operating temperature, as well as good long-term stability towards acetone. After incorporation of Au (2.0 wt%), the detection limit of Au-doped ZnO sensor decreases to 5 ppb and the response increases to 17 under 1 ppm acetone at 150℃, which is more than triple the responses of ZnO sensor. The results demonstrate that the developed Au-doped ZnO sensor has great potential for ppb-level acetone detection in human breath for diagnosing diabetes.
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